DE1593099A1 - A-Nor-5 alpha-gonan-Derivate und Verfahren zu ihrer Herstellung - Google Patents

A-Nor-5 alpha-gonan-Derivate und Verfahren zu ihrer Herstellung

Info

Publication number
DE1593099A1
DE1593099A1 DE19661593099 DE1593099A DE1593099A1 DE 1593099 A1 DE1593099 A1 DE 1593099A1 DE 19661593099 DE19661593099 DE 19661593099 DE 1593099 A DE1593099 A DE 1593099A DE 1593099 A1 DE1593099 A1 DE 1593099A1
Authority
DE
Germany
Prior art keywords
gonan
methyl
hydroxy
alkyl
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19661593099
Other languages
German (de)
English (en)
Inventor
Jean Jacques
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE1593099A1 publication Critical patent/DE1593099A1/de
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
DE19661593099 1965-10-21 1966-10-20 A-Nor-5 alpha-gonan-Derivate und Verfahren zu ihrer Herstellung Pending DE1593099A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50034465A 1965-10-21 1965-10-21
US56400566A 1966-07-11 1966-07-11

Publications (1)

Publication Number Publication Date
DE1593099A1 true DE1593099A1 (de) 1970-06-18

Family

ID=27053485

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19661593099 Pending DE1593099A1 (de) 1965-10-21 1966-10-20 A-Nor-5 alpha-gonan-Derivate und Verfahren zu ihrer Herstellung

Country Status (5)

Country Link
BR (1) BR6683858D0 (enExample)
CH (1) CH503010A (enExample)
DE (1) DE1593099A1 (enExample)
GB (1) GB1169739A (enExample)
NL (1) NL6614986A (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3520019A1 (de) * 1984-06-04 1986-01-09 Showa Denko K.K., Tokio/Tokyo Verfahren zur herstellung von epichlorhydrin

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3520019A1 (de) * 1984-06-04 1986-01-09 Showa Denko K.K., Tokio/Tokyo Verfahren zur herstellung von epichlorhydrin

Also Published As

Publication number Publication date
CH503010A (de) 1971-02-15
NL6614986A (enExample) 1967-04-24
GB1169739A (en) 1969-11-05
BR6683858D0 (pt) 1973-12-04

Similar Documents

Publication Publication Date Title
DE2653558A1 (de) 16 beta-alkyloestradiolderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE1543273A1 (de) Verfahren zur Herstellung von 7alpha-Methylsteroiden der Oestranreihe
DE1618980B2 (de) In 17-stellung substituierte 11, 13beta-dialkylgon-4-en-3,17beta-diole und deren ester
DE1568308B2 (de) Verfahren zur herstellung von delta hoch 4,9,11-trienen der 19-nor- androstanreihe, 17-oxygenierte 3-oxo- 7 alpha-methyl-delta hoch 4,9,11-19 nor- androstatriene und diese enthaltende pharmazeutische praeparate sowie 3-oxo-7 alpha -methyl-delta hoch 5 (10), 9 (11) -19-nor- androstadiene
DE1468905C3 (de) Verfahren zur Herstellung von 3 beta, 6 beta-Dihydroxy-(bzw. Diacyloxy> Delta hoch 5(10) -19-nor-Steroiden und einige dieser Verbindungen
DE1593099A1 (de) A-Nor-5 alpha-gonan-Derivate und Verfahren zu ihrer Herstellung
DE1793618C3 (de) 07.03.63 USA 263441 Verfahren zur Herstellung von 3-Hydroxy-1,5-bisdehydrosteroiden der Androstanreihe
US3270007A (en) Process for cyclopentanophenanthrene compounds
DE1468985A1 (de) 17alpha-Alkyl-,17alpha-Alkenyl- und 17alpha-Alkinyl-4,5-epoxy-19-norandrostan-17beta-diole und deren Carbonsaeureester sowie Verfahren zur Herstellung dieser Verbindungen
DE1239306B (de) Verfahren zur Herstellung von Ketosteroiden, die in alpha-Stellung zur Ketogruppe eine gegebenenfalls substituierte Allylgruppe tragen
DE1643005C3 (de) 15,16beta-Methylen-testosterone, Verfahren zu ihrer Herstellung sowie diese Steroide enthaltende Mittel
DE1263000B (de) Neues Verfahren zur Herstellung von Gemischen aus delta 1,3,5(10)-3-Oxysteroiden und delta 1,3,5(10)9(11)-3-Oxysteroiden bzw. von delta 1,3,5(10)-3-Oxysteroiden
DE1240859B (de) Verfahren zur Herstellung von Androstan-1alpha, 3alpha, 17beta-triol und seinen Estern
DE2336431C2 (de) 1.3-oxygenierte 8 alpha-Östratriene, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE1793608B1 (de) 17alpha-Alkyl-,-Alkenyl- oder -Alkinyl-13ss-alkylgon-4-oder-5(10)-en-17ss-ol-3-one
DE1961906C3 (de) 7 a-Methyl-androstenolone, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel
DE1568013C3 (de) 17 alpha - eckige Klammer auf 3'-Furyl eckige Klammer zu -steroide, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE2409991C3 (de) Steroidätherspaltung
DE1593687C (de) Verfahren zur Herstellung von neuen Benzo eckige Klammer auf d,e eckige Klam mer zu steroiden der Androstan und Preg nanreihe
DE1468988C (de) nalpha-Chloräthinyl-lSbeta-äthyl-4-oder-5( 10)- gonen-3 -ketone.'
AT266349B (de) Verfahren zur Herstellung von neuen 9β,10α-Steroiden
DE1493165B2 (de) 1-Hydroxyöstradiol-Derivate, Verfahren zu ihrer Herstellung sowie diese enthaltendes Mittel
DE1203260B (de) Verfahren zur Herstellung von 2-Formyl-A2-androstenderivaten
DE1618960A1 (de) Neue Steroide und Verfahren zu ihrer Herstellung
DE1618063A1 (de) Steroidverbindungen,ihre Herstellung und Verwendung