DE1518361B1 - L-Ornithin-L-asparaginat und Verfahren zu seiner Herstellung - Google Patents

L-Ornithin-L-asparaginat und Verfahren zu seiner Herstellung

Info

Publication number
DE1518361B1
DE1518361B1 DE19631518361 DE1518361A DE1518361B1 DE 1518361 B1 DE1518361 B1 DE 1518361B1 DE 19631518361 DE19631518361 DE 19631518361 DE 1518361 A DE1518361 A DE 1518361A DE 1518361 B1 DE1518361 B1 DE 1518361B1
Authority
DE
Germany
Prior art keywords
ornithine
aspartic acid
asparaginate
methanol
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19631518361
Other languages
German (de)
English (en)
Inventor
Kyuji Abe
Mitsutaka Kawazu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Pharma Corp
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Publication of DE1518361B1 publication Critical patent/DE1518361B1/de
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/20Synthetic spices, flavouring agents or condiments
    • A23L27/21Synthetic spices, flavouring agents or condiments containing amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05Dipeptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE19631518361 1962-04-23 1963-04-22 L-Ornithin-L-asparaginat und Verfahren zu seiner Herstellung Pending DE1518361B1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1654062 1962-04-23

Publications (1)

Publication Number Publication Date
DE1518361B1 true DE1518361B1 (de) 1969-11-13

Family

ID=11919082

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19631518361 Pending DE1518361B1 (de) 1962-04-23 1963-04-22 L-Ornithin-L-asparaginat und Verfahren zu seiner Herstellung

Country Status (7)

Country Link
AT (1) AT246344B (https=)
BR (1) BR6348588D0 (https=)
CH (1) CH434285A (https=)
DE (1) DE1518361B1 (https=)
DK (1) DK109694C (https=)
FR (1) FR4048M (https=)
GB (1) GB965637A (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE789856A (fr) * 1971-10-13 1973-02-01 Tixier Georges Medicament a base de derives de la lysine susceptibles de stimuler differents metabolismes, en particulier la genese des leucocytes
US3832465A (en) * 1971-12-09 1974-08-27 H Ghadimi Injectable amino acid composition commensurate to the anabolic need of the body and method of using same
FR2495608A1 (fr) * 1980-12-04 1982-06-11 Morelle Jean Nouveaux derives de l'acide aspartique et leurs usages
US4972634A (en) * 1989-01-19 1990-11-27 Dresden Gregory M Portable walling
ATE116285T1 (de) * 1990-09-28 1995-01-15 Kyowa Hakko Kogyo Kk Verfahren zur herstellung von kristallen eines salzes von sauerer aminosäure und basischer aminosäure.
SG158073A1 (en) 2004-11-26 2010-01-29 Ucl Business Plc Compositions comprising ornithine and phenylacetate or phenylbutyrate for treating hepatic encephalopathy
CA2757373C (en) 2009-04-03 2018-05-08 Ocera Therapeutics, Inc. L-ornithine phenyl acetate and methods of making thereof
EA201691430A1 (ru) 2009-06-08 2017-02-28 ЮСиЭл БИЗНЕС ПиЭлСи Лечение портальной гипертензии и восстановление функции печени с помощью l-орнитинфенилацетата
MX360062B (es) 2010-10-06 2018-10-22 Ocera Therapeutics Inc Metodos de elaboracion de fenilacetato de l-ornitina.
CN102993037B (zh) * 2012-11-20 2015-03-04 南京工业大学 一种l-鸟氨酸苯乙酸盐的制备方法
US10039735B2 (en) 2014-11-24 2018-08-07 Ucl Business Plc Treatment of diseases associated with hepatic stellate cell activation using ammonia-lowering therapies
BR112018001410A2 (pt) * 2015-07-24 2018-09-11 Evonik Technochemie Gmbh formulações efervescentes de aspartato de ornitina
EP3337473A4 (en) 2015-08-18 2019-04-17 Ocera Therapeutics, Inc. TREATMENT AND PREVENTION OF MUSCLE WOUND BY L-ORNITHIN IN COMBINATION WITH AT LEAST ONE PHENYL ACETATE AND PHENYL BUTYRATE
WO2018208677A1 (en) 2017-05-11 2018-11-15 Ocera Therapeutics, Inc. Processes of making l-ornithine phenylacetate

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
None *

Also Published As

Publication number Publication date
FR4048M (https=) 1966-04-04
BR6348588D0 (pt) 1973-07-03
CH434285A (de) 1967-04-30
AT246344B (de) 1966-04-12
DK109694C (da) 1968-06-10
GB965637A (en) 1964-08-06

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