DD274766A5 - Verfahren zur herstellung einer pharmazeutischen formulierung - Google Patents
Verfahren zur herstellung einer pharmazeutischen formulierung Download PDFInfo
- Publication number
- DD274766A5 DD274766A5 DD87320503A DD32050387A DD274766A5 DD 274766 A5 DD274766 A5 DD 274766A5 DD 87320503 A DD87320503 A DD 87320503A DD 32050387 A DD32050387 A DD 32050387A DD 274766 A5 DD274766 A5 DD 274766A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- compound
- formula
- group
- active ingredient
- evaporated
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Silicon Polymers (AREA)
- Developing Agents For Electrophotography (AREA)
- Apparatus For Radiation Diagnosis (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB868629892A GB8629892D0 (en) | 1986-12-15 | 1986-12-15 | Antiviral compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
DD274766A5 true DD274766A5 (de) | 1990-01-03 |
Family
ID=10609013
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DD87320503A DD274766A5 (de) | 1986-12-15 | 1987-12-14 | Verfahren zur herstellung einer pharmazeutischen formulierung |
DD87310427A DD264924A5 (de) | 1986-12-15 | 1987-12-14 | Verfahren zur herstellung von pyrimidin-nucleosiden |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DD87310427A DD264924A5 (de) | 1986-12-15 | 1987-12-14 | Verfahren zur herstellung von pyrimidin-nucleosiden |
Country Status (30)
Country | Link |
---|---|
US (1) | US5079235A (ko) |
EP (3) | EP0486477A3 (ko) |
JP (2) | JPS63165397A (ko) |
KR (1) | KR880007521A (ko) |
CN (2) | CN87108265A (ko) |
AT (1) | ATE88713T1 (ko) |
AU (2) | AU601529B2 (ko) |
CA (1) | CA1319143C (ko) |
CS (3) | CS275402B6 (ko) |
DD (2) | DD274766A5 (ko) |
DE (1) | DE3785651T2 (ko) |
DK (2) | DK654287A (ko) |
ES (1) | ES2054693T3 (ko) |
FI (2) | FI875487A (ko) |
GB (1) | GB8629892D0 (ko) |
HU (4) | HU200932B (ko) |
IE (2) | IE930470L (ko) |
IL (3) | IL95141A (ko) |
LT (1) | LT2064B (ko) |
LV (1) | LV5273A3 (ko) |
MC (1) | MC1882A1 (ko) |
MX (1) | MX9203216A (ko) |
NO (1) | NO167576C (ko) |
NZ (1) | NZ222898A (ko) |
PH (2) | PH24104A (ko) |
PL (3) | PL160321B1 (ko) |
PT (1) | PT86356B (ko) |
RU (1) | RU2036199C1 (ko) |
SU (1) | SU1731064A3 (ko) |
ZA (1) | ZA879382B (ko) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ225176A (en) * | 1987-06-24 | 1990-09-26 | Florey Howard Inst | Nucleoside derivatives |
US4954485A (en) * | 1987-10-20 | 1990-09-04 | Sanyo-Kokusaku Pulp Co., Ltd. | 2',3'-dideoxy-4-thio-uridine derivatives, process for their preparation and antivirus agents using them |
EP0346108A3 (en) * | 1988-06-09 | 1991-04-24 | The Wellcome Foundation Limited | Anti-infective nucleosides |
US5157114A (en) * | 1988-08-19 | 1992-10-20 | Burroughs Wellcome Co. | 2',3'-dideoxy-3'-fluoro-5-ethyngluridine |
GB8827339D0 (en) * | 1988-11-23 | 1988-12-29 | Wellcome Found | Antiviral compounds |
US5006646A (en) * | 1989-02-22 | 1991-04-09 | Yuki Gosei Kogyo Co., Ltd. | Process for preparing 2'-deoxy-5-trifluoromethyl-beta-uridine |
IE902574A1 (en) * | 1989-07-17 | 1991-02-27 | Univ Birmingham | Antiviral pyrimidine nucleosides |
DD293498A5 (de) * | 1989-07-20 | 1991-09-05 | Zi Fuer Molekularbiologie Der Adw,De | Verfahren zur herstellung eines mittels fuer die behandlung oder prophylaxe von hepatits-infektionen bei mensch und tier |
GB8919607D0 (en) * | 1989-08-30 | 1989-10-11 | Wellcome Found | Novel entities for cancer therapy |
US6337209B1 (en) | 1992-02-26 | 2002-01-08 | Glaxo Wellcome Inc. | Molecular constructs containing a carcinoembryonic antigen regulatory sequence |
GB9008696D0 (en) * | 1990-04-18 | 1990-06-13 | Wellcome Found | Anti-viral compounds |
GB9012899D0 (en) * | 1990-06-09 | 1990-08-01 | Wellcome Found | Anti-hbv pyrimidine nucleoside |
GB9014618D0 (en) * | 1990-06-30 | 1990-08-22 | Wellcome Found | Process for the preparation of pyrimidine nucleosides |
US5643913A (en) * | 1990-07-19 | 1997-07-01 | Glaxo Wellcome Inc. | Pharmaceutical compositions of 5-substituted uracil compounds |
EP0539442B1 (en) | 1990-07-19 | 1998-01-07 | The Wellcome Foundation Limited | Enzyme inactivators |
GB9020930D0 (en) * | 1990-09-26 | 1990-11-07 | Wellcome Found | Pharmaceutical combinations |
GB9104165D0 (en) * | 1991-02-27 | 1991-04-17 | Wellcome Found | Novel entities for hiv therapy |
GB9111580D0 (en) * | 1991-05-30 | 1991-07-24 | Wellcome Found | Nucleoside derivative |
US5646123A (en) * | 1991-06-10 | 1997-07-08 | Alberta Research Council | Time dependent administration of oligosaccharide glycosides related to blood group determinants having a type I or type II core structure in reducing inflammation in a sensitized mammal arising form exposure to an antigen |
US5580858A (en) * | 1991-06-10 | 1996-12-03 | Alberta Research Council | Immunosuppressive and tolerogenic modified Lewisx compounds |
HU207524B (en) * | 1991-11-22 | 1993-04-28 | Mta Koezponti Kemiai Kutato In | Industrial process for producing 5-alkyl-2'-deoxy-beta-uridines with stereoselective synthesis |
DE637965T1 (de) * | 1991-11-26 | 1995-12-14 | Gilead Sciences Inc | Gesteigerte bildung von triple- und doppelhelices aus oligomeren mit modifizierten pyrimidinen. |
TW393513B (en) * | 1991-11-26 | 2000-06-11 | Isis Pharmaceuticals Inc | Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines |
US5484908A (en) * | 1991-11-26 | 1996-01-16 | Gilead Sciences, Inc. | Oligonucleotides containing 5-propynyl pyrimidines |
US6235887B1 (en) | 1991-11-26 | 2001-05-22 | Isis Pharmaceuticals, Inc. | Enhanced triple-helix and double-helix formation directed by oligonucleotides containing modified pyrimidines |
CA2118405A1 (en) * | 1992-05-26 | 1993-09-12 | Robert Maurice Ippolito | Immunosuppressive and tolerogenic modified lewisc and lacnac compounds |
CA2119315A1 (en) * | 1993-03-18 | 1994-09-19 | Tsujiaki Hata | Nucleoside derivatives and anti-herpes composition |
US6432924B1 (en) | 1993-12-26 | 2002-08-13 | East Carolina University | Method of treating disorders characterized by overexpression of cytidine deaminase or deoxycytidine deaminase |
CA2241255A1 (en) * | 1995-12-22 | 1997-07-03 | East Carolina University | Method of treating disorders characterized by overexpression of cytidine deaminase or deoxycytidine deaminase |
WO1997027849A1 (fr) * | 1996-02-02 | 1997-08-07 | Showa Shell Sekiyu K.K. | Medicaments pour traiter les infections provoquees par le virus de l'herpes et compositions preventives pour empecher un retour de l'infection, contenant tous les deux des derives triterpeniques comme principe actif |
US6653318B1 (en) * | 1999-07-21 | 2003-11-25 | Yale University | 5-(E)-Bromovinyl uracil analogues and related pyrimidine nucleosides as anti-viral agents and methods of use |
US7019129B1 (en) | 2000-05-09 | 2006-03-28 | Biosearch Technologies, Inc. | Dark quenchers for donor-acceptor energy transfer |
JP4651942B2 (ja) * | 2001-12-20 | 2011-03-16 | フアーマセツト・インコーポレイテッド | Ebv及びkhsv感染並びにそれに伴う異常細胞増殖の治療 |
CN101068549A (zh) | 2004-12-03 | 2007-11-07 | 阿迪赫里克斯技术公司 | 与5-fu和5-fu前药组合施用dpd抑制剂的方法 |
SI2757091T1 (en) | 2008-04-01 | 2018-01-31 | Biosearch Technologies, Inc. | Stabilized nucleic acid black gas-fluorofor probe |
CN101768197A (zh) * | 2008-12-29 | 2010-07-07 | 北京德众万全药物技术开发有限公司 | 一种奈拉滨的制备方法 |
CN102811721A (zh) | 2009-10-14 | 2012-12-05 | 阿迪赫里克斯技术公司 | 治疗与5-fu或5-fu前药联合的dpd抑制剂给药相关的神经毒性的方法 |
AU2015241034B2 (en) * | 2014-03-30 | 2020-02-06 | Cepheid | Modified cytosine polynucleotide oligomers and methods |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1601020A (en) | 1978-04-24 | 1981-10-21 | Stichting Grega Vzw | 2'-deoxy-5 (2-halogenovinyl)-uridines |
US4211773A (en) * | 1978-10-02 | 1980-07-08 | Sloan Kettering Institute For Cancer Research | 5-Substituted 1-(2'-Deoxy-2'-substituted-β-D-arabinofuranosyl)pyrimidine nucleosides |
US4267171A (en) * | 1979-07-02 | 1981-05-12 | The Regents Of The University Of California | C-5 Substituted cytosine nucleosides |
US4247544A (en) * | 1979-07-02 | 1981-01-27 | The Regents Of The University Of California | C-5 Substituted uracil nucleosides |
US4274544A (en) * | 1980-03-11 | 1981-06-23 | The Continental Group, Inc. | Single-piece plastic closure having integral seal forming means |
EP0082668A1 (en) * | 1981-12-18 | 1983-06-29 | Beecham Group Plc | 5-(2-Halogenovinyl)-2'-deoxyuridine derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in treating viral infections |
EP0082667A1 (en) * | 1981-12-18 | 1983-06-29 | Beecham Group Plc | Pharmaceutical compositions |
EP0095294A1 (en) * | 1982-05-22 | 1983-11-30 | Beecham Group Plc | Deoxyuridine compounds, methods for preparing them and their use in medicine |
EP0097039A1 (en) * | 1982-06-16 | 1983-12-28 | Beecham Group Plc | 5-(E-2-halovinyl)-2'-deoxyuridine derivatives, processes for their preparation, pharmaceutical compositions containing them, and their use in treating viral infections |
GB8517402D0 (en) * | 1985-07-10 | 1985-08-14 | Wellcome Found | Treatment of viral infections |
ATE190064T1 (de) * | 1985-09-17 | 2000-03-15 | Wellcome Found | Kombination therapeutische nukleoside mit weiteren therapeutisch wirksamen komponenten. |
SE8701605D0 (sv) * | 1987-04-16 | 1987-04-16 | Astra Ab | Novel medicinal compounds |
-
1986
- 1986-12-15 GB GB868629892A patent/GB8629892D0/en active Pending
-
1987
- 1987-12-14 CS CS877675A patent/CS275402B6/cs unknown
- 1987-12-14 AT AT87310951T patent/ATE88713T1/de not_active IP Right Cessation
- 1987-12-14 ZA ZA879382A patent/ZA879382B/xx unknown
- 1987-12-14 IL IL95141A patent/IL95141A/xx unknown
- 1987-12-14 EP EP19920103712 patent/EP0486477A3/en not_active Withdrawn
- 1987-12-14 EP EP87310951A patent/EP0272065B1/en not_active Expired - Lifetime
- 1987-12-14 JP JP62315960A patent/JPS63165397A/ja active Granted
- 1987-12-14 HU HU893368A patent/HU200932B/hu not_active IP Right Cessation
- 1987-12-14 DE DE87310951T patent/DE3785651T2/de not_active Expired - Fee Related
- 1987-12-14 DD DD87320503A patent/DD274766A5/de not_active IP Right Cessation
- 1987-12-14 IE IE930470A patent/IE930470L/xx unknown
- 1987-12-14 MC MC871936A patent/MC1882A1/xx unknown
- 1987-12-14 IE IE930471A patent/IE930471L/xx unknown
- 1987-12-14 NO NO875209A patent/NO167576C/no unknown
- 1987-12-14 CS CS879161A patent/CS275398B2/cs unknown
- 1987-12-14 DK DK654287A patent/DK654287A/da not_active Application Discontinuation
- 1987-12-14 PL PL1987277926A patent/PL160321B1/pl unknown
- 1987-12-14 PH PH36211A patent/PH24104A/en unknown
- 1987-12-14 PL PL1987277927A patent/PL160322B1/pl unknown
- 1987-12-14 HU HU875642A patent/HU199867B/hu not_active IP Right Cessation
- 1987-12-14 CS CS913425A patent/CS342591A3/cs unknown
- 1987-12-14 FI FI875487A patent/FI875487A/fi not_active Application Discontinuation
- 1987-12-14 ES ES87310951T patent/ES2054693T3/es not_active Expired - Lifetime
- 1987-12-14 SU SU874355176A patent/SU1731064A3/ru active
- 1987-12-14 NZ NZ222898A patent/NZ222898A/en unknown
- 1987-12-14 KR KR870014274A patent/KR880007521A/ko not_active Application Discontinuation
- 1987-12-14 HU HU893367A patent/HU202112B/hu not_active IP Right Cessation
- 1987-12-14 CA CA000554258A patent/CA1319143C/en not_active Expired - Fee Related
- 1987-12-14 IL IL84810A patent/IL84810A/xx not_active IP Right Cessation
- 1987-12-14 PL PL1987269462A patent/PL158050B1/pl unknown
- 1987-12-14 DD DD87310427A patent/DD264924A5/de not_active IP Right Cessation
- 1987-12-14 EP EP90116634A patent/EP0417560A1/en not_active Withdrawn
- 1987-12-14 CN CN198787108265A patent/CN87108265A/zh active Pending
- 1987-12-14 HU HU903829A patent/HU207735B/hu not_active IP Right Cessation
- 1987-12-14 PT PT86356A patent/PT86356B/pt not_active IP Right Cessation
- 1987-12-14 AU AU82521/87A patent/AU601529B2/en not_active Ceased
-
1988
- 1988-07-05 PH PH37174A patent/PH24870A/en unknown
-
1989
- 1989-05-26 RU SU894614158A patent/RU2036199C1/ru active
-
1990
- 1990-01-16 US US07/465,552 patent/US5079235A/en not_active Expired - Lifetime
- 1990-07-20 IL IL95141A patent/IL95141A0/xx unknown
- 1990-07-26 AU AU59890/90A patent/AU626041B2/en not_active Ceased
- 1990-10-08 JP JP2270325A patent/JPH03141292A/ja active Pending
-
1991
- 1991-10-04 DK DK169991A patent/DK168323B1/da not_active IP Right Cessation
-
1992
- 1992-06-24 MX MX9203216A patent/MX9203216A/es unknown
- 1992-12-18 LV LV920338A patent/LV5273A3/xx unknown
- 1992-12-30 LT LTRP271A patent/LT2064B/xx unknown
-
1993
- 1993-02-27 CN CN93102155A patent/CN1080292A/zh active Pending
-
1994
- 1994-03-31 FI FI941523A patent/FI941523A0/fi not_active Application Discontinuation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ENJ | Ceased due to non-payment of renewal fee |