MC1882A1 - Composes anti-viraux - Google Patents
Composes anti-virauxInfo
- Publication number
- MC1882A1 MC1882A1 MC871936A MC1936A MC1882A1 MC 1882 A1 MC1882 A1 MC 1882A1 MC 871936 A MC871936 A MC 871936A MC 1936 A MC1936 A MC 1936A MC 1882 A1 MC1882 A1 MC 1882A1
- Authority
- MC
- Monaco
- Prior art keywords
- viral compounds
- cytomegalovirus
- prophylaxis
- pharmaceutically acceptable
- processes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Developing Agents For Electrophotography (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Silicon Polymers (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB868629892A GB8629892D0 (en) | 1986-12-15 | 1986-12-15 | Antiviral compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
MC1882A1 true MC1882A1 (fr) | 1989-01-24 |
Family
ID=10609013
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MC871936A MC1882A1 (fr) | 1986-12-15 | 1987-12-14 | Composes anti-viraux |
Country Status (30)
Country | Link |
---|---|
US (1) | US5079235A (ko) |
EP (3) | EP0486477A3 (ko) |
JP (2) | JPS63165397A (ko) |
KR (1) | KR880007521A (ko) |
CN (2) | CN87108265A (ko) |
AT (1) | ATE88713T1 (ko) |
AU (2) | AU601529B2 (ko) |
CA (1) | CA1319143C (ko) |
CS (3) | CS275402B6 (ko) |
DD (2) | DD264924A5 (ko) |
DE (1) | DE3785651T2 (ko) |
DK (2) | DK654287A (ko) |
ES (1) | ES2054693T3 (ko) |
FI (2) | FI875487A (ko) |
GB (1) | GB8629892D0 (ko) |
HU (4) | HU199867B (ko) |
IE (2) | IE930470L (ko) |
IL (3) | IL95141A (ko) |
LT (1) | LT2064B (ko) |
LV (1) | LV5273A3 (ko) |
MC (1) | MC1882A1 (ko) |
MX (1) | MX9203216A (ko) |
NO (1) | NO167576C (ko) |
NZ (1) | NZ222898A (ko) |
PH (2) | PH24104A (ko) |
PL (3) | PL160321B1 (ko) |
PT (1) | PT86356B (ko) |
RU (1) | RU2036199C1 (ko) |
SU (1) | SU1731064A3 (ko) |
ZA (1) | ZA879382B (ko) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2828642B2 (ja) * | 1987-06-24 | 1998-11-25 | ハワード フローレイ インスティテュト オブ イクスペリメンタル フィジオロジー アンド メディシン | ヌクレオシド誘導体 |
US4954485A (en) * | 1987-10-20 | 1990-09-04 | Sanyo-Kokusaku Pulp Co., Ltd. | 2',3'-dideoxy-4-thio-uridine derivatives, process for their preparation and antivirus agents using them |
EP0346108A3 (en) * | 1988-06-09 | 1991-04-24 | The Wellcome Foundation Limited | Anti-infective nucleosides |
US5157114A (en) * | 1988-08-19 | 1992-10-20 | Burroughs Wellcome Co. | 2',3'-dideoxy-3'-fluoro-5-ethyngluridine |
GB8827339D0 (en) * | 1988-11-23 | 1988-12-29 | Wellcome Found | Antiviral compounds |
US5006646A (en) * | 1989-02-22 | 1991-04-09 | Yuki Gosei Kogyo Co., Ltd. | Process for preparing 2'-deoxy-5-trifluoromethyl-beta-uridine |
NZ234534A (en) * | 1989-07-17 | 1994-12-22 | Univ Birmingham | Pyrimidine 4'-thionucleoside derivatives and their preparation; intermediates therefor |
DD293498A5 (de) * | 1989-07-20 | 1991-09-05 | Zi Fuer Molekularbiologie Der Adw,De | Verfahren zur herstellung eines mittels fuer die behandlung oder prophylaxe von hepatits-infektionen bei mensch und tier |
GB8919607D0 (en) | 1989-08-30 | 1989-10-11 | Wellcome Found | Novel entities for cancer therapy |
US6337209B1 (en) | 1992-02-26 | 2002-01-08 | Glaxo Wellcome Inc. | Molecular constructs containing a carcinoembryonic antigen regulatory sequence |
GB9008696D0 (en) * | 1990-04-18 | 1990-06-13 | Wellcome Found | Anti-viral compounds |
GB9012899D0 (en) * | 1990-06-09 | 1990-08-01 | Wellcome Found | Anti-hbv pyrimidine nucleoside |
GB9014618D0 (en) * | 1990-06-30 | 1990-08-22 | Wellcome Found | Process for the preparation of pyrimidine nucleosides |
DK0539442T3 (da) * | 1990-07-19 | 1998-09-07 | Wellcome Found | Enzyminaktivatorer |
US5643913A (en) * | 1990-07-19 | 1997-07-01 | Glaxo Wellcome Inc. | Pharmaceutical compositions of 5-substituted uracil compounds |
GB9020930D0 (en) * | 1990-09-26 | 1990-11-07 | Wellcome Found | Pharmaceutical combinations |
GB9104165D0 (en) * | 1991-02-27 | 1991-04-17 | Wellcome Found | Novel entities for hiv therapy |
GB9111580D0 (en) * | 1991-05-30 | 1991-07-24 | Wellcome Found | Nucleoside derivative |
US5580858A (en) * | 1991-06-10 | 1996-12-03 | Alberta Research Council | Immunosuppressive and tolerogenic modified Lewisx compounds |
US5646123A (en) * | 1991-06-10 | 1997-07-08 | Alberta Research Council | Time dependent administration of oligosaccharide glycosides related to blood group determinants having a type I or type II core structure in reducing inflammation in a sensitized mammal arising form exposure to an antigen |
HU207524B (en) * | 1991-11-22 | 1993-04-28 | Mta Koezponti Kemiai Kutato In | Industrial process for producing 5-alkyl-2'-deoxy-beta-uridines with stereoselective synthesis |
TW393513B (en) * | 1991-11-26 | 2000-06-11 | Isis Pharmaceuticals Inc | Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines |
US6235887B1 (en) | 1991-11-26 | 2001-05-22 | Isis Pharmaceuticals, Inc. | Enhanced triple-helix and double-helix formation directed by oligonucleotides containing modified pyrimidines |
DE69232816T2 (de) * | 1991-11-26 | 2003-06-18 | Isis Pharmaceuticals, Inc. | Gesteigerte bildung von triple- und doppelhelices aus oligomeren mit modifizierten pyrimidinen |
US5484908A (en) * | 1991-11-26 | 1996-01-16 | Gilead Sciences, Inc. | Oligonucleotides containing 5-propynyl pyrimidines |
WO1993024506A1 (en) * | 1992-05-26 | 1993-12-09 | Alberta Research Council | IMMUNOSUPPRESSIVE AND TOLEROGENIC MODIFIED LEWISC AND LacNAc COMPOUNDS |
CA2119315A1 (en) * | 1993-03-18 | 1994-09-19 | Tsujiaki Hata | Nucleoside derivatives and anti-herpes composition |
US6432924B1 (en) | 1993-12-26 | 2002-08-13 | East Carolina University | Method of treating disorders characterized by overexpression of cytidine deaminase or deoxycytidine deaminase |
AU728377C (en) * | 1995-12-22 | 2003-10-30 | East Carolina University | Method of treating disorders characterized by overexpression of cytidine deaminase or deoxycytidine deaminase |
EP0878193A1 (en) * | 1996-02-02 | 1998-11-18 | Showa Shell Sekiyu K.K. | Remedies for herpesvirus infection caused by herpesvirus and preventives for recurrence of the infection both containing triterpene derivatives as the active ingredient |
US6653318B1 (en) | 1999-07-21 | 2003-11-25 | Yale University | 5-(E)-Bromovinyl uracil analogues and related pyrimidine nucleosides as anti-viral agents and methods of use |
US7019129B1 (en) | 2000-05-09 | 2006-03-28 | Biosearch Technologies, Inc. | Dark quenchers for donor-acceptor energy transfer |
WO2003053360A2 (en) * | 2001-12-20 | 2003-07-03 | Pharmassett Ltd. | Treatment of ebv and khsv infection and associated abnormal cellular proliferation |
MX2007006646A (es) | 2004-12-03 | 2007-11-16 | Adherex Technologies Inc | Metodos para administrar inhibidores de dihidropirimidina deshidrogenasa en combinacion con 5-fluorouracilo y profarmacos de 5-fluorouracilo. |
JP5669721B2 (ja) | 2008-04-01 | 2015-02-12 | バイオサーチ テクノロジーズ,インコーポレイテッド | 安定化核酸ダーククエンチャー−フルオロフォアプローブ |
CN101768197A (zh) * | 2008-12-29 | 2010-07-07 | 北京德众万全药物技术开发有限公司 | 一种奈拉滨的制备方法 |
JP2013508293A (ja) | 2009-10-14 | 2013-03-07 | アドヘレックス テクノロジーズ, インコーポレイテッド | 5−fu又はそのプロドラッグと、dpd阻害剤との組合せに付随した神経毒性の処置 |
CA2944155C (en) * | 2014-03-30 | 2023-08-29 | Cepheid | Modified cytosine polynucleotide oligomers and methods |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1601020A (en) | 1978-04-24 | 1981-10-21 | Stichting Grega Vzw | 2'-deoxy-5 (2-halogenovinyl)-uridines |
US4211773A (en) * | 1978-10-02 | 1980-07-08 | Sloan Kettering Institute For Cancer Research | 5-Substituted 1-(2'-Deoxy-2'-substituted-β-D-arabinofuranosyl)pyrimidine nucleosides |
US4247544A (en) * | 1979-07-02 | 1981-01-27 | The Regents Of The University Of California | C-5 Substituted uracil nucleosides |
US4267171A (en) * | 1979-07-02 | 1981-05-12 | The Regents Of The University Of California | C-5 Substituted cytosine nucleosides |
US4274544A (en) * | 1980-03-11 | 1981-06-23 | The Continental Group, Inc. | Single-piece plastic closure having integral seal forming means |
EP0082667A1 (en) * | 1981-12-18 | 1983-06-29 | Beecham Group Plc | Pharmaceutical compositions |
EP0082668A1 (en) * | 1981-12-18 | 1983-06-29 | Beecham Group Plc | 5-(2-Halogenovinyl)-2'-deoxyuridine derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in treating viral infections |
EP0095294A1 (en) * | 1982-05-22 | 1983-11-30 | Beecham Group Plc | Deoxyuridine compounds, methods for preparing them and their use in medicine |
EP0097039A1 (en) * | 1982-06-16 | 1983-12-28 | Beecham Group Plc | 5-(E-2-halovinyl)-2'-deoxyuridine derivatives, processes for their preparation, pharmaceutical compositions containing them, and their use in treating viral infections |
GB8517402D0 (en) * | 1985-07-10 | 1985-08-14 | Wellcome Found | Treatment of viral infections |
GB2181128A (en) * | 1985-09-17 | 1987-04-15 | Wellcome Found | 3'-azidonucleosides |
SE8701605D0 (sv) * | 1987-04-16 | 1987-04-16 | Astra Ab | Novel medicinal compounds |
-
1986
- 1986-12-15 GB GB868629892A patent/GB8629892D0/en active Pending
-
1987
- 1987-12-14 HU HU875642A patent/HU199867B/hu not_active IP Right Cessation
- 1987-12-14 CS CS877675A patent/CS275402B6/cs unknown
- 1987-12-14 CS CS879161A patent/CS275398B2/cs unknown
- 1987-12-14 PL PL1987277926A patent/PL160321B1/pl unknown
- 1987-12-14 SU SU874355176A patent/SU1731064A3/ru active
- 1987-12-14 PT PT86356A patent/PT86356B/pt not_active IP Right Cessation
- 1987-12-14 HU HU903829A patent/HU207735B/hu not_active IP Right Cessation
- 1987-12-14 DK DK654287A patent/DK654287A/da not_active Application Discontinuation
- 1987-12-14 AT AT87310951T patent/ATE88713T1/de not_active IP Right Cessation
- 1987-12-14 DD DD87310427A patent/DD264924A5/de not_active IP Right Cessation
- 1987-12-14 MC MC871936A patent/MC1882A1/xx unknown
- 1987-12-14 PH PH36211A patent/PH24104A/en unknown
- 1987-12-14 DD DD87320503A patent/DD274766A5/de not_active IP Right Cessation
- 1987-12-14 EP EP19920103712 patent/EP0486477A3/en not_active Withdrawn
- 1987-12-14 DE DE87310951T patent/DE3785651T2/de not_active Expired - Fee Related
- 1987-12-14 IE IE930470A patent/IE930470L/xx unknown
- 1987-12-14 HU HU893368A patent/HU200932B/hu not_active IP Right Cessation
- 1987-12-14 CN CN198787108265A patent/CN87108265A/zh active Pending
- 1987-12-14 IL IL95141A patent/IL95141A/xx unknown
- 1987-12-14 AU AU82521/87A patent/AU601529B2/en not_active Ceased
- 1987-12-14 JP JP62315960A patent/JPS63165397A/ja active Granted
- 1987-12-14 NZ NZ222898A patent/NZ222898A/en unknown
- 1987-12-14 PL PL1987277927A patent/PL160322B1/pl unknown
- 1987-12-14 FI FI875487A patent/FI875487A/fi not_active Application Discontinuation
- 1987-12-14 PL PL1987269462A patent/PL158050B1/pl unknown
- 1987-12-14 ZA ZA879382A patent/ZA879382B/xx unknown
- 1987-12-14 IE IE930471A patent/IE930471L/xx unknown
- 1987-12-14 EP EP87310951A patent/EP0272065B1/en not_active Expired - Lifetime
- 1987-12-14 CS CS913425A patent/CS342591A3/cs unknown
- 1987-12-14 ES ES87310951T patent/ES2054693T3/es not_active Expired - Lifetime
- 1987-12-14 NO NO875209A patent/NO167576C/no unknown
- 1987-12-14 EP EP90116634A patent/EP0417560A1/en not_active Withdrawn
- 1987-12-14 CA CA000554258A patent/CA1319143C/en not_active Expired - Fee Related
- 1987-12-14 KR KR870014274A patent/KR880007521A/ko not_active Application Discontinuation
- 1987-12-14 HU HU893367A patent/HU202112B/hu not_active IP Right Cessation
- 1987-12-14 IL IL84810A patent/IL84810A/xx not_active IP Right Cessation
-
1988
- 1988-07-05 PH PH37174A patent/PH24870A/en unknown
-
1989
- 1989-05-26 RU SU894614158A patent/RU2036199C1/ru active
-
1990
- 1990-01-16 US US07/465,552 patent/US5079235A/en not_active Expired - Lifetime
- 1990-07-20 IL IL95141A patent/IL95141A0/xx unknown
- 1990-07-26 AU AU59890/90A patent/AU626041B2/en not_active Ceased
- 1990-10-08 JP JP2270325A patent/JPH03141292A/ja active Pending
-
1991
- 1991-10-04 DK DK169991A patent/DK168323B1/da not_active IP Right Cessation
-
1992
- 1992-06-24 MX MX9203216A patent/MX9203216A/es unknown
- 1992-12-18 LV LV920338A patent/LV5273A3/xx unknown
- 1992-12-30 LT LTRP271A patent/LT2064B/xx unknown
-
1993
- 1993-02-27 CN CN93102155A patent/CN1080292A/zh active Pending
-
1994
- 1994-03-31 FI FI941523A patent/FI941523A/fi not_active Application Discontinuation
Also Published As
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Publication | Publication Date | Title |
---|---|---|
MC1882A1 (fr) | Composes anti-viraux | |
DE3679353D1 (de) | Antivirale verbindungen. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
YP | Annual fee paid |