LT2064B - Pirimidininiu nukleozidu gavimo budas - Google Patents
Pirimidininiu nukleozidu gavimo budasInfo
- Publication number
- LT2064B LT2064B LTRP271A LTRP271A LT2064B LT 2064 B LT2064 B LT 2064B LT RP271 A LTRP271 A LT RP271A LT RP271 A LTRP271 A LT RP271A LT 2064 B LT2064 B LT 2064B
- Authority
- LT
- Lithuania
- Prior art keywords
- nucleosid
- pyrimidin
- price
- reception
- cytomegalovirus
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Silicon Polymers (AREA)
- Developing Agents For Electrophotography (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB868629892A GB8629892D0 (en) | 1986-12-15 | 1986-12-15 | Antiviral compounds |
SU874355176A SU1731064A3 (ru) | 1986-12-15 | 1987-12-14 | Способ получени пиримидиновых нуклеозидов |
Publications (1)
Publication Number | Publication Date |
---|---|
LT2064B true LT2064B (lt) | 1993-06-15 |
Family
ID=10609013
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LTRP271A LT2064B (lt) | 1986-12-15 | 1992-12-30 | Pirimidininiu nukleozidu gavimo budas |
Country Status (30)
Country | Link |
---|---|
US (1) | US5079235A (lt) |
EP (3) | EP0417560A1 (lt) |
JP (2) | JPS63165397A (lt) |
KR (1) | KR880007521A (lt) |
CN (2) | CN87108265A (lt) |
AT (1) | ATE88713T1 (lt) |
AU (2) | AU601529B2 (lt) |
CA (1) | CA1319143C (lt) |
CS (3) | CS275398B2 (lt) |
DD (2) | DD274766A5 (lt) |
DE (1) | DE3785651T2 (lt) |
DK (2) | DK654287A (lt) |
ES (1) | ES2054693T3 (lt) |
FI (2) | FI875487A (lt) |
GB (1) | GB8629892D0 (lt) |
HU (4) | HU199867B (lt) |
IE (2) | IE930471L (lt) |
IL (3) | IL95141A (lt) |
LT (1) | LT2064B (lt) |
LV (1) | LV5273A3 (lt) |
MC (1) | MC1882A1 (lt) |
MX (1) | MX9203216A (lt) |
NO (1) | NO167576C (lt) |
NZ (1) | NZ222898A (lt) |
PH (2) | PH24104A (lt) |
PL (3) | PL158050B1 (lt) |
PT (1) | PT86356B (lt) |
RU (1) | RU2036199C1 (lt) |
SU (1) | SU1731064A3 (lt) |
ZA (1) | ZA879382B (lt) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE113059T1 (de) * | 1987-06-24 | 1994-11-15 | Florey Howard Inst | Nukleosid-derivate. |
US4954485A (en) * | 1987-10-20 | 1990-09-04 | Sanyo-Kokusaku Pulp Co., Ltd. | 2',3'-dideoxy-4-thio-uridine derivatives, process for their preparation and antivirus agents using them |
EP0346108A3 (en) * | 1988-06-09 | 1991-04-24 | The Wellcome Foundation Limited | Anti-infective nucleosides |
US5157114A (en) * | 1988-08-19 | 1992-10-20 | Burroughs Wellcome Co. | 2',3'-dideoxy-3'-fluoro-5-ethyngluridine |
GB8827339D0 (en) * | 1988-11-23 | 1988-12-29 | Wellcome Found | Antiviral compounds |
US5006646A (en) * | 1989-02-22 | 1991-04-09 | Yuki Gosei Kogyo Co., Ltd. | Process for preparing 2'-deoxy-5-trifluoromethyl-beta-uridine |
NZ234534A (en) * | 1989-07-17 | 1994-12-22 | Univ Birmingham | Pyrimidine 4'-thionucleoside derivatives and their preparation; intermediates therefor |
DD293498A5 (de) * | 1989-07-20 | 1991-09-05 | Zi Fuer Molekularbiologie Der Adw,De | Verfahren zur herstellung eines mittels fuer die behandlung oder prophylaxe von hepatits-infektionen bei mensch und tier |
US6337209B1 (en) | 1992-02-26 | 2002-01-08 | Glaxo Wellcome Inc. | Molecular constructs containing a carcinoembryonic antigen regulatory sequence |
GB8919607D0 (en) * | 1989-08-30 | 1989-10-11 | Wellcome Found | Novel entities for cancer therapy |
GB9008696D0 (en) * | 1990-04-18 | 1990-06-13 | Wellcome Found | Anti-viral compounds |
GB9012899D0 (en) * | 1990-06-09 | 1990-08-01 | Wellcome Found | Anti-hbv pyrimidine nucleoside |
GB9014618D0 (en) * | 1990-06-30 | 1990-08-22 | Wellcome Found | Process for the preparation of pyrimidine nucleosides |
DK0539442T3 (da) * | 1990-07-19 | 1998-09-07 | Wellcome Found | Enzyminaktivatorer |
US5643913A (en) * | 1990-07-19 | 1997-07-01 | Glaxo Wellcome Inc. | Pharmaceutical compositions of 5-substituted uracil compounds |
GB9020930D0 (en) | 1990-09-26 | 1990-11-07 | Wellcome Found | Pharmaceutical combinations |
GB9104165D0 (en) * | 1991-02-27 | 1991-04-17 | Wellcome Found | Novel entities for hiv therapy |
GB9111580D0 (en) * | 1991-05-30 | 1991-07-24 | Wellcome Found | Nucleoside derivative |
US5580858A (en) * | 1991-06-10 | 1996-12-03 | Alberta Research Council | Immunosuppressive and tolerogenic modified Lewisx compounds |
US5646123A (en) * | 1991-06-10 | 1997-07-08 | Alberta Research Council | Time dependent administration of oligosaccharide glycosides related to blood group determinants having a type I or type II core structure in reducing inflammation in a sensitized mammal arising form exposure to an antigen |
HU207524B (en) * | 1991-11-22 | 1993-04-28 | Mta Koezponti Kemiai Kutato In | Industrial process for producing 5-alkyl-2'-deoxy-beta-uridines with stereoselective synthesis |
US5484908A (en) * | 1991-11-26 | 1996-01-16 | Gilead Sciences, Inc. | Oligonucleotides containing 5-propynyl pyrimidines |
ATE226093T1 (de) * | 1991-11-26 | 2002-11-15 | Isis Pharmaceuticals Inc | Gesteigerte bildung von triple- und doppelhelices aus oligomeren mit modifizierten pyrimidinen |
TW393513B (en) * | 1991-11-26 | 2000-06-11 | Isis Pharmaceuticals Inc | Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines |
US6235887B1 (en) | 1991-11-26 | 2001-05-22 | Isis Pharmaceuticals, Inc. | Enhanced triple-helix and double-helix formation directed by oligonucleotides containing modified pyrimidines |
EP0643718A4 (en) * | 1992-05-26 | 1998-08-05 | Alberta Res Council | IMMUNOSUPPRESIVE AND TOLEROGENIC MODIFIED LEWIS C AND LacNac CONNECTIONS. |
CA2119315A1 (en) * | 1993-03-18 | 1994-09-19 | Tsujiaki Hata | Nucleoside derivatives and anti-herpes composition |
US6432924B1 (en) | 1993-12-26 | 2002-08-13 | East Carolina University | Method of treating disorders characterized by overexpression of cytidine deaminase or deoxycytidine deaminase |
EP0876149A4 (en) * | 1995-12-22 | 2001-09-26 | Univ East Carolina | PROCESS FOR THE TREATMENT OF CHARACTERIZED DISORDERS BY OVEREXPRESSION OF CYTIDINE-DESAMINASE OR DESOXYCYTIDINE-DESAMINASE |
WO1997027849A1 (fr) * | 1996-02-02 | 1997-08-07 | Showa Shell Sekiyu K.K. | Medicaments pour traiter les infections provoquees par le virus de l'herpes et compositions preventives pour empecher un retour de l'infection, contenant tous les deux des derives triterpeniques comme principe actif |
US6653318B1 (en) | 1999-07-21 | 2003-11-25 | Yale University | 5-(E)-Bromovinyl uracil analogues and related pyrimidine nucleosides as anti-viral agents and methods of use |
US7019129B1 (en) | 2000-05-09 | 2006-03-28 | Biosearch Technologies, Inc. | Dark quenchers for donor-acceptor energy transfer |
EP1569658A4 (en) * | 2001-12-20 | 2007-05-30 | Pharmassett Ltd | TREATMENT OF EPSTEIN-BARR VIRUS, INFECTION WITH KAPOSI-ASSOCIATED SARCOMA HERPESVIRUS AND ABNORMAL CELL PROLIFERATION |
CN102441170A (zh) | 2004-12-03 | 2012-05-09 | 阿迪赫里克斯技术公司 | 与5-fu和5-fu前药组合施用dpd抑制剂的方法 |
DK2757091T3 (en) | 2008-04-01 | 2017-08-14 | Biosearch Tech Inc | PROBLEMS FOR STABILIZED NUCLEIC ACID DARK-QUENCHER FLUOROPHOR |
CN101768197A (zh) * | 2008-12-29 | 2010-07-07 | 北京德众万全药物技术开发有限公司 | 一种奈拉滨的制备方法 |
CA2777546C (en) | 2009-10-14 | 2019-11-05 | Adherex Technologies, Inc. | Treating neurotoxicity associated with combinations of 5-fu or its prodrugs and dpd inhibitors |
US9598456B2 (en) * | 2014-03-30 | 2017-03-21 | Cepheid | Modified cytosine polynucleotide oligomers and methods |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1601020A (en) * | 1978-04-24 | 1981-10-21 | Stichting Grega Vzw | 2'-deoxy-5 (2-halogenovinyl)-uridines |
US4211773A (en) * | 1978-10-02 | 1980-07-08 | Sloan Kettering Institute For Cancer Research | 5-Substituted 1-(2'-Deoxy-2'-substituted-β-D-arabinofuranosyl)pyrimidine nucleosides |
US4247544A (en) * | 1979-07-02 | 1981-01-27 | The Regents Of The University Of California | C-5 Substituted uracil nucleosides |
US4267171A (en) * | 1979-07-02 | 1981-05-12 | The Regents Of The University Of California | C-5 Substituted cytosine nucleosides |
US4274544A (en) * | 1980-03-11 | 1981-06-23 | The Continental Group, Inc. | Single-piece plastic closure having integral seal forming means |
EP0082667A1 (en) * | 1981-12-18 | 1983-06-29 | Beecham Group Plc | Pharmaceutical compositions |
EP0082668A1 (en) * | 1981-12-18 | 1983-06-29 | Beecham Group Plc | 5-(2-Halogenovinyl)-2'-deoxyuridine derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in treating viral infections |
EP0095294A1 (en) * | 1982-05-22 | 1983-11-30 | Beecham Group Plc | Deoxyuridine compounds, methods for preparing them and their use in medicine |
EP0097039A1 (en) * | 1982-06-16 | 1983-12-28 | Beecham Group Plc | 5-(E-2-halovinyl)-2'-deoxyuridine derivatives, processes for their preparation, pharmaceutical compositions containing them, and their use in treating viral infections |
GB8517402D0 (en) * | 1985-07-10 | 1985-08-14 | Wellcome Found | Treatment of viral infections |
DK167377B1 (da) * | 1985-09-17 | 1993-10-25 | Wellcome Found | 3'-azidopyrimidinnucleosider eller farmaceutisk acceptable salte eller estere deraf til anvendelse ved behandling af eller profylakse for en human retrovirusinfektion |
SE8701605D0 (sv) * | 1987-04-16 | 1987-04-16 | Astra Ab | Novel medicinal compounds |
-
1986
- 1986-12-15 GB GB868629892A patent/GB8629892D0/en active Pending
-
1987
- 1987-12-14 PL PL1987269462A patent/PL158050B1/pl unknown
- 1987-12-14 IL IL95141A patent/IL95141A/xx unknown
- 1987-12-14 MC MC871936A patent/MC1882A1/xx unknown
- 1987-12-14 HU HU875642A patent/HU199867B/hu not_active IP Right Cessation
- 1987-12-14 EP EP90116634A patent/EP0417560A1/en not_active Withdrawn
- 1987-12-14 NO NO875209A patent/NO167576C/no unknown
- 1987-12-14 DD DD87320503A patent/DD274766A5/de not_active IP Right Cessation
- 1987-12-14 NZ NZ222898A patent/NZ222898A/en unknown
- 1987-12-14 CS CS879161A patent/CS275398B2/cs unknown
- 1987-12-14 CN CN198787108265A patent/CN87108265A/zh active Pending
- 1987-12-14 SU SU874355176A patent/SU1731064A3/ru active
- 1987-12-14 AT AT87310951T patent/ATE88713T1/de not_active IP Right Cessation
- 1987-12-14 FI FI875487A patent/FI875487A/fi not_active Application Discontinuation
- 1987-12-14 PT PT86356A patent/PT86356B/pt not_active IP Right Cessation
- 1987-12-14 HU HU893367A patent/HU202112B/hu not_active IP Right Cessation
- 1987-12-14 PL PL1987277927A patent/PL160322B1/pl unknown
- 1987-12-14 DE DE87310951T patent/DE3785651T2/de not_active Expired - Fee Related
- 1987-12-14 ZA ZA879382A patent/ZA879382B/xx unknown
- 1987-12-14 DD DD87310427A patent/DD264924A5/de not_active IP Right Cessation
- 1987-12-14 HU HU903829A patent/HU207735B/hu not_active IP Right Cessation
- 1987-12-14 AU AU82521/87A patent/AU601529B2/en not_active Ceased
- 1987-12-14 PH PH36211A patent/PH24104A/en unknown
- 1987-12-14 IL IL84810A patent/IL84810A/xx not_active IP Right Cessation
- 1987-12-14 IE IE930471A patent/IE930471L/xx unknown
- 1987-12-14 EP EP87310951A patent/EP0272065B1/en not_active Expired - Lifetime
- 1987-12-14 CS CS877675A patent/CS275402B6/cs unknown
- 1987-12-14 DK DK654287A patent/DK654287A/da not_active Application Discontinuation
- 1987-12-14 CS CS913425A patent/CS342591A3/cs unknown
- 1987-12-14 IE IE930470A patent/IE930470L/xx unknown
- 1987-12-14 EP EP19920103712 patent/EP0486477A3/en not_active Withdrawn
- 1987-12-14 HU HU893368A patent/HU200932B/hu not_active IP Right Cessation
- 1987-12-14 ES ES87310951T patent/ES2054693T3/es not_active Expired - Lifetime
- 1987-12-14 KR KR870014274A patent/KR880007521A/ko not_active Application Discontinuation
- 1987-12-14 JP JP62315960A patent/JPS63165397A/ja active Granted
- 1987-12-14 PL PL1987277926A patent/PL160321B1/pl unknown
- 1987-12-14 CA CA000554258A patent/CA1319143C/en not_active Expired - Fee Related
-
1988
- 1988-07-05 PH PH37174A patent/PH24870A/en unknown
-
1989
- 1989-05-26 RU SU894614158A patent/RU2036199C1/ru active
-
1990
- 1990-01-16 US US07/465,552 patent/US5079235A/en not_active Expired - Lifetime
- 1990-07-20 IL IL95141A patent/IL95141A0/xx unknown
- 1990-07-26 AU AU59890/90A patent/AU626041B2/en not_active Ceased
- 1990-10-08 JP JP2270325A patent/JPH03141292A/ja active Pending
-
1991
- 1991-10-04 DK DK169991A patent/DK168323B1/da not_active IP Right Cessation
-
1992
- 1992-06-24 MX MX9203216A patent/MX9203216A/es unknown
- 1992-12-18 LV LV920338A patent/LV5273A3/xx unknown
- 1992-12-30 LT LTRP271A patent/LT2064B/lt unknown
-
1993
- 1993-02-27 CN CN93102155A patent/CN1080292A/zh active Pending
-
1994
- 1994-03-31 FI FI941523A patent/FI941523A/fi not_active Application Discontinuation
Also Published As
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Publication | Publication Date | Title |
---|---|---|
LT2064B (lt) | Pirimidininiu nukleozidu gavimo budas | |
ATE63747T1 (de) | Antivirale verbindungen. |