ATE63747T1 - Antivirale verbindungen. - Google Patents
Antivirale verbindungen.Info
- Publication number
- ATE63747T1 ATE63747T1 AT86305297T AT86305297T ATE63747T1 AT E63747 T1 ATE63747 T1 AT E63747T1 AT 86305297 T AT86305297 T AT 86305297T AT 86305297 T AT86305297 T AT 86305297T AT E63747 T1 ATE63747 T1 AT E63747T1
- Authority
- AT
- Austria
- Prior art keywords
- antiviral compounds
- ethynyluridine
- deoxy
- prophylaxis
- processes
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 230000000840 anti-viral effect Effects 0.000 title 1
- CDEURGJCGCHYFH-DJLDLDEBSA-N 5-ethynyl-2'-deoxyuridine Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C(C#C)=C1 CDEURGJCGCHYFH-DJLDLDEBSA-N 0.000 abstract 1
- 206010011831 Cytomegalovirus infection Diseases 0.000 abstract 1
- 241000701085 Human alphaherpesvirus 3 Species 0.000 abstract 1
- 208000005181 Varicella Zoster Virus Infection Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
- 208000010531 varicella zoster infection Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB858517402A GB8517402D0 (en) | 1985-07-10 | 1985-07-10 | Treatment of viral infections |
| EP86305297A EP0208550B1 (de) | 1985-07-10 | 1986-07-09 | Antivirale Verbindungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE63747T1 true ATE63747T1 (de) | 1991-06-15 |
Family
ID=10582066
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86305297T ATE63747T1 (de) | 1985-07-10 | 1986-07-09 | Antivirale verbindungen. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4863906A (de) |
| EP (1) | EP0208550B1 (de) |
| JP (1) | JPS6212793A (de) |
| AT (1) | ATE63747T1 (de) |
| AU (1) | AU581329B2 (de) |
| DE (1) | DE3679353D1 (de) |
| DK (1) | DK326586A (de) |
| ES (1) | ES2000323A6 (de) |
| GB (1) | GB8517402D0 (de) |
| NZ (1) | NZ216798A (de) |
| ZA (1) | ZA865130B (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8629892D0 (en) * | 1986-12-15 | 1987-01-28 | Wellcome Found | Antiviral compounds |
| US5215971A (en) * | 1986-12-19 | 1993-06-01 | Medivir Ab | Antiviral pharmaceutical composition comprising 5-substituted pyrimidine nucleosides |
| US5215970A (en) * | 1987-04-16 | 1993-06-01 | Medivir Ab | Nucleosides and nucleotide analogues, pharmaceutical composition and processes for the preparation of the compounds |
| JP2828642B2 (ja) * | 1987-06-24 | 1998-11-25 | ハワード フローレイ インスティテュト オブ イクスペリメンタル フィジオロジー アンド メディシン | ヌクレオシド誘導体 |
| CA1301166C (en) * | 1987-07-21 | 1992-05-19 | John Nicholas Freskos | Process for preparing 2-deoxynucleosides |
| US5028596A (en) * | 1987-12-14 | 1991-07-02 | Burroughs Wellcome Co. | 1-(β-D-arabinofuranosyl)-5-propynyluracil for treatment of VZV infections |
| EP0346108A3 (de) * | 1988-06-09 | 1991-04-24 | The Wellcome Foundation Limited | Anti-infektiöse Nukleoside |
| US5157114A (en) * | 1988-08-19 | 1992-10-20 | Burroughs Wellcome Co. | 2',3'-dideoxy-3'-fluoro-5-ethyngluridine |
| HU207524B (en) * | 1991-11-22 | 1993-04-28 | Mta Koezponti Kemiai Kutato In | Industrial process for producing 5-alkyl-2'-deoxy-beta-uridines with stereoselective synthesis |
| EP0828750B1 (de) * | 1995-06-02 | 2013-07-17 | EC Technology LLC | Palladiumkatalysierte verfahren zur modifikation von nukleosiden unter verwendung von nukleophilen und kohlenmonoxid |
| US20080096817A1 (en) * | 1998-07-30 | 2008-04-24 | Regenerx Biopharmaceuticals, Inc. | METHODS OF TREATING DISORDERS OF THE EYE AND SURROUNDING TISSUE WITH THYMOSIN BETA 4 (Tbeta4), ANALOGUES, ISOFORMS AND OTHER DERIVATIVES |
| US20040067227A1 (en) * | 2001-11-02 | 2004-04-08 | Goldstein Allan L. | Inhibition or reversal of skin aging by actin-sequestering peptides |
| EP2311485A1 (de) * | 1998-07-30 | 2011-04-20 | The Government of the United States of America, as represented by the Secretary of Health and Human Services | Thymosin beta 4 stimuliert Wundheilung |
| US6653318B1 (en) * | 1999-07-21 | 2003-11-25 | Yale University | 5-(E)-Bromovinyl uracil analogues and related pyrimidine nucleosides as anti-viral agents and methods of use |
| US6624096B2 (en) * | 2001-08-20 | 2003-09-23 | Cna Holdings, Inc. | Textile fabric for the outer shell of a firefighters's garmet |
| CA3103422A1 (en) * | 2018-06-13 | 2019-12-19 | Wilian Holding Company | Heavy duty spanning forms and related systems and methods |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1601020A (en) * | 1978-04-24 | 1981-10-21 | Stichting Grega Vzw | 2'-deoxy-5 (2-halogenovinyl)-uridines |
| US4247544A (en) * | 1979-07-02 | 1981-01-27 | The Regents Of The University Of California | C-5 Substituted uracil nucleosides |
| HU183567B (en) * | 1981-09-07 | 1984-05-28 | Mta Koezponti Kemiai Kutato In | Process for preparing /e/-5-/2-bromo-vinyl/-uridine and derivatives thereof |
| EP0082668A1 (de) * | 1981-12-18 | 1983-06-29 | Beecham Group Plc | 5-(2-Halogenvinyl)-2'-Deoxyuridinderivate, Verfahren zu ihrer Herstellung, die sie enthaltende pharmazeutische Präparate und ihre Verwendung bei der Bekämpfung von viralen Infektionen |
| US4782142A (en) * | 1982-01-05 | 1988-11-01 | The Research Foundation Of State University Of New York | Novel 5-substituted 2-pyrimidinone nucleosides and methods of use |
| US4594339A (en) * | 1982-04-06 | 1986-06-10 | Sloan-Kettering Institute For Cancer Research | Anti-herpes virus compositions containing 5-substituted 1-2'(deoxy-2-'-substituted-β-d-arabinofuranosyl)pyrimedene nucleosides |
| US4666777A (en) | 1985-12-23 | 1987-05-19 | The Dow Chemical Company | Structured latex core-shell polymer particles suitable for use in the preparation of composite sheets |
-
1985
- 1985-07-10 GB GB858517402A patent/GB8517402D0/en active Pending
-
1986
- 1986-07-09 DK DK326586A patent/DK326586A/da not_active Application Discontinuation
- 1986-07-09 EP EP86305297A patent/EP0208550B1/de not_active Expired - Lifetime
- 1986-07-09 AT AT86305297T patent/ATE63747T1/de not_active IP Right Cessation
- 1986-07-09 AU AU60055/86A patent/AU581329B2/en not_active Ceased
- 1986-07-09 NZ NZ216798A patent/NZ216798A/xx unknown
- 1986-07-09 JP JP61161748A patent/JPS6212793A/ja active Pending
- 1986-07-09 ES ES8600199A patent/ES2000323A6/es not_active Expired
- 1986-07-09 DE DE8686305297T patent/DE3679353D1/de not_active Expired - Fee Related
- 1986-07-09 ZA ZA865130A patent/ZA865130B/xx unknown
- 1986-07-10 US US06/883,913 patent/US4863906A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ZA865130B (en) | 1988-02-24 |
| EP0208550B1 (de) | 1991-05-22 |
| AU581329B2 (en) | 1989-02-16 |
| AU6005586A (en) | 1987-01-15 |
| JPS6212793A (ja) | 1987-01-21 |
| EP0208550A3 (en) | 1988-04-20 |
| DE3679353D1 (de) | 1991-06-27 |
| NZ216798A (en) | 1990-02-26 |
| DK326586D0 (da) | 1986-07-09 |
| US4863906A (en) | 1989-09-05 |
| EP0208550A2 (de) | 1987-01-14 |
| ES2000323A6 (es) | 1988-02-16 |
| DK326586A (da) | 1987-01-11 |
| GB8517402D0 (en) | 1985-08-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX9203216A (es) | Compuestos antivirales. | |
| NL300302I2 (nl) | Antivirale verbindingen. | |
| ATE63747T1 (de) | Antivirale verbindungen. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |