DK654287A - Antivirale forbindelser - Google Patents
Antivirale forbindelserInfo
- Publication number
- DK654287A DK654287A DK654287A DK654287A DK654287A DK 654287 A DK654287 A DK 654287A DK 654287 A DK654287 A DK 654287A DK 654287 A DK654287 A DK 654287A DK 654287 A DK654287 A DK 654287A
- Authority
- DK
- Denmark
- Prior art keywords
- antiviral
- relations
- cytomegalovirus
- prophylaxis
- pharmaceutically acceptable
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Developing Agents For Electrophotography (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Silicon Polymers (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB868629892A GB8629892D0 (en) | 1986-12-15 | 1986-12-15 | Antiviral compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
DK654287D0 DK654287D0 (da) | 1987-12-14 |
DK654287A true DK654287A (da) | 1988-06-16 |
Family
ID=10609013
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK654287A DK654287A (da) | 1986-12-15 | 1987-12-14 | Antivirale forbindelser |
DK169991A DK168323B1 (da) | 1986-12-15 | 1991-10-04 | Anvendelse af visse pyrimidinnucleosider til fremstilling af et lægemiddel mod VZV-infektioner; hidtil ukendte pyrimidinnucleosider, sådanne forbindelser til anvendelse i human terapi samt fremgangsmåde til fremstilling af forbindelserne |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK169991A DK168323B1 (da) | 1986-12-15 | 1991-10-04 | Anvendelse af visse pyrimidinnucleosider til fremstilling af et lægemiddel mod VZV-infektioner; hidtil ukendte pyrimidinnucleosider, sådanne forbindelser til anvendelse i human terapi samt fremgangsmåde til fremstilling af forbindelserne |
Country Status (30)
Country | Link |
---|---|
US (1) | US5079235A (da) |
EP (3) | EP0272065B1 (da) |
JP (2) | JPS63165397A (da) |
KR (1) | KR880007521A (da) |
CN (2) | CN87108265A (da) |
AT (1) | ATE88713T1 (da) |
AU (2) | AU601529B2 (da) |
CA (1) | CA1319143C (da) |
CS (3) | CS342591A3 (da) |
DD (2) | DD264924A5 (da) |
DE (1) | DE3785651T2 (da) |
DK (2) | DK654287A (da) |
ES (1) | ES2054693T3 (da) |
FI (2) | FI875487A (da) |
GB (1) | GB8629892D0 (da) |
HU (4) | HU199867B (da) |
IE (2) | IE930471L (da) |
IL (3) | IL84810A (da) |
LT (1) | LT2064B (da) |
LV (1) | LV5273A3 (da) |
MC (1) | MC1882A1 (da) |
MX (1) | MX9203216A (da) |
NO (1) | NO167576C (da) |
NZ (1) | NZ222898A (da) |
PH (2) | PH24104A (da) |
PL (3) | PL158050B1 (da) |
PT (1) | PT86356B (da) |
RU (1) | RU2036199C1 (da) |
SU (1) | SU1731064A3 (da) |
ZA (1) | ZA879382B (da) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU598946B2 (en) * | 1987-06-24 | 1990-07-05 | Howard Florey Institute Of Experimental Physiology And Medicine | Nucleoside derivatives |
US4954485A (en) * | 1987-10-20 | 1990-09-04 | Sanyo-Kokusaku Pulp Co., Ltd. | 2',3'-dideoxy-4-thio-uridine derivatives, process for their preparation and antivirus agents using them |
EP0346108A3 (en) * | 1988-06-09 | 1991-04-24 | The Wellcome Foundation Limited | Anti-infective nucleosides |
US5157114A (en) * | 1988-08-19 | 1992-10-20 | Burroughs Wellcome Co. | 2',3'-dideoxy-3'-fluoro-5-ethyngluridine |
GB8827339D0 (en) * | 1988-11-23 | 1988-12-29 | Wellcome Found | Antiviral compounds |
US5006646A (en) * | 1989-02-22 | 1991-04-09 | Yuki Gosei Kogyo Co., Ltd. | Process for preparing 2'-deoxy-5-trifluoromethyl-beta-uridine |
NZ234534A (en) * | 1989-07-17 | 1994-12-22 | Univ Birmingham | Pyrimidine 4'-thionucleoside derivatives and their preparation; intermediates therefor |
DD293498A5 (de) * | 1989-07-20 | 1991-09-05 | Zi Fuer Molekularbiologie Der Adw,De | Verfahren zur herstellung eines mittels fuer die behandlung oder prophylaxe von hepatits-infektionen bei mensch und tier |
US6337209B1 (en) | 1992-02-26 | 2002-01-08 | Glaxo Wellcome Inc. | Molecular constructs containing a carcinoembryonic antigen regulatory sequence |
GB8919607D0 (en) * | 1989-08-30 | 1989-10-11 | Wellcome Found | Novel entities for cancer therapy |
GB9008696D0 (en) * | 1990-04-18 | 1990-06-13 | Wellcome Found | Anti-viral compounds |
GB9012899D0 (en) * | 1990-06-09 | 1990-08-01 | Wellcome Found | Anti-hbv pyrimidine nucleoside |
GB9014618D0 (en) * | 1990-06-30 | 1990-08-22 | Wellcome Found | Process for the preparation of pyrimidine nucleosides |
WO1992001452A1 (en) | 1990-07-19 | 1992-02-06 | The Wellcome Foundation Limited | Enzyme inactivators |
US5643913A (en) * | 1990-07-19 | 1997-07-01 | Glaxo Wellcome Inc. | Pharmaceutical compositions of 5-substituted uracil compounds |
GB9020930D0 (en) * | 1990-09-26 | 1990-11-07 | Wellcome Found | Pharmaceutical combinations |
GB9104165D0 (en) * | 1991-02-27 | 1991-04-17 | Wellcome Found | Novel entities for hiv therapy |
GB9111580D0 (en) * | 1991-05-30 | 1991-07-24 | Wellcome Found | Nucleoside derivative |
US5580858A (en) * | 1991-06-10 | 1996-12-03 | Alberta Research Council | Immunosuppressive and tolerogenic modified Lewisx compounds |
US5646123A (en) * | 1991-06-10 | 1997-07-08 | Alberta Research Council | Time dependent administration of oligosaccharide glycosides related to blood group determinants having a type I or type II core structure in reducing inflammation in a sensitized mammal arising form exposure to an antigen |
HU207524B (en) * | 1991-11-22 | 1993-04-28 | Mta Koezponti Kemiai Kutato In | Industrial process for producing 5-alkyl-2'-deoxy-beta-uridines with stereoselective synthesis |
TW393513B (en) * | 1991-11-26 | 2000-06-11 | Isis Pharmaceuticals Inc | Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines |
CA2122365C (en) * | 1991-11-26 | 2010-05-11 | Brian Froehler | Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines |
US5484908A (en) * | 1991-11-26 | 1996-01-16 | Gilead Sciences, Inc. | Oligonucleotides containing 5-propynyl pyrimidines |
US6235887B1 (en) | 1991-11-26 | 2001-05-22 | Isis Pharmaceuticals, Inc. | Enhanced triple-helix and double-helix formation directed by oligonucleotides containing modified pyrimidines |
WO1993024506A1 (en) * | 1992-05-26 | 1993-12-09 | Alberta Research Council | IMMUNOSUPPRESSIVE AND TOLEROGENIC MODIFIED LEWISC AND LacNAc COMPOUNDS |
CA2119315A1 (en) * | 1993-03-18 | 1994-09-19 | Tsujiaki Hata | Nucleoside derivatives and anti-herpes composition |
US6432924B1 (en) | 1993-12-26 | 2002-08-13 | East Carolina University | Method of treating disorders characterized by overexpression of cytidine deaminase or deoxycytidine deaminase |
KR19990076695A (ko) * | 1995-12-22 | 1999-10-15 | 리차드 알. 이킨 | 시티딘 데아미나제 혹은 데옥시시티딘 데아미나제의 과발현과연관된 질병들을 치료하기 위한 활성제_및 방법 |
EP0878193A1 (en) * | 1996-02-02 | 1998-11-18 | Showa Shell Sekiyu K.K. | Remedies for herpesvirus infection caused by herpesvirus and preventives for recurrence of the infection both containing triterpene derivatives as the active ingredient |
US6653318B1 (en) | 1999-07-21 | 2003-11-25 | Yale University | 5-(E)-Bromovinyl uracil analogues and related pyrimidine nucleosides as anti-viral agents and methods of use |
US7019129B1 (en) | 2000-05-09 | 2006-03-28 | Biosearch Technologies, Inc. | Dark quenchers for donor-acceptor energy transfer |
EP1569658A4 (en) * | 2001-12-20 | 2007-05-30 | Pharmassett Ltd | TREATMENT OF EPSTEIN-BARR VIRUS, INFECTION WITH KAPOSI-ASSOCIATED SARCOMA HERPESVIRUS AND ABNORMAL CELL PROLIFERATION |
MX2007006646A (es) | 2004-12-03 | 2007-11-16 | Adherex Technologies Inc | Metodos para administrar inhibidores de dihidropirimidina deshidrogenasa en combinacion con 5-fluorouracilo y profarmacos de 5-fluorouracilo. |
PL2757091T3 (pl) | 2008-04-01 | 2017-10-31 | Biosearch Tech Inc | Stabilizowane ciemne wygaszające sondy fluoroforowe kwasu nukleinowego |
CN101768197A (zh) * | 2008-12-29 | 2010-07-07 | 北京德众万全药物技术开发有限公司 | 一种奈拉滨的制备方法 |
CN102811721A (zh) | 2009-10-14 | 2012-12-05 | 阿迪赫里克斯技术公司 | 治疗与5-fu或5-fu前药联合的dpd抑制剂给药相关的神经毒性的方法 |
WO2015153510A1 (en) * | 2014-03-30 | 2015-10-08 | Cepheid | Modified cytosine polynucleotide oligomers and methods |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1601020A (en) * | 1978-04-24 | 1981-10-21 | Stichting Grega Vzw | 2'-deoxy-5 (2-halogenovinyl)-uridines |
US4211773A (en) * | 1978-10-02 | 1980-07-08 | Sloan Kettering Institute For Cancer Research | 5-Substituted 1-(2'-Deoxy-2'-substituted-β-D-arabinofuranosyl)pyrimidine nucleosides |
US4267171A (en) * | 1979-07-02 | 1981-05-12 | The Regents Of The University Of California | C-5 Substituted cytosine nucleosides |
US4247544A (en) * | 1979-07-02 | 1981-01-27 | The Regents Of The University Of California | C-5 Substituted uracil nucleosides |
US4274544A (en) * | 1980-03-11 | 1981-06-23 | The Continental Group, Inc. | Single-piece plastic closure having integral seal forming means |
EP0082667A1 (en) * | 1981-12-18 | 1983-06-29 | Beecham Group Plc | Pharmaceutical compositions |
EP0082668A1 (en) * | 1981-12-18 | 1983-06-29 | Beecham Group Plc | 5-(2-Halogenovinyl)-2'-deoxyuridine derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in treating viral infections |
EP0095294A1 (en) * | 1982-05-22 | 1983-11-30 | Beecham Group Plc | Deoxyuridine compounds, methods for preparing them and their use in medicine |
EP0097039A1 (en) * | 1982-06-16 | 1983-12-28 | Beecham Group Plc | 5-(E-2-halovinyl)-2'-deoxyuridine derivatives, processes for their preparation, pharmaceutical compositions containing them, and their use in treating viral infections |
GB8517402D0 (en) * | 1985-07-10 | 1985-08-14 | Wellcome Found | Treatment of viral infections |
EP0217580A3 (en) * | 1985-09-17 | 1990-11-07 | The Wellcome Foundation Limited | Therapeutic nucleosides |
SE8701605D0 (sv) * | 1987-04-16 | 1987-04-16 | Astra Ab | Novel medicinal compounds |
-
1986
- 1986-12-15 GB GB868629892A patent/GB8629892D0/en active Pending
-
1987
- 1987-12-14 NZ NZ222898A patent/NZ222898A/en unknown
- 1987-12-14 EP EP87310951A patent/EP0272065B1/en not_active Expired - Lifetime
- 1987-12-14 HU HU875642A patent/HU199867B/hu not_active IP Right Cessation
- 1987-12-14 AT AT87310951T patent/ATE88713T1/de not_active IP Right Cessation
- 1987-12-14 IE IE930471A patent/IE930471L/xx unknown
- 1987-12-14 DD DD87310427A patent/DD264924A5/de not_active IP Right Cessation
- 1987-12-14 IL IL84810A patent/IL84810A/xx not_active IP Right Cessation
- 1987-12-14 CS CS913425A patent/CS342591A3/cs unknown
- 1987-12-14 EP EP19920103712 patent/EP0486477A3/en not_active Withdrawn
- 1987-12-14 JP JP62315960A patent/JPS63165397A/ja active Granted
- 1987-12-14 IL IL95141A patent/IL95141A/xx unknown
- 1987-12-14 DE DE87310951T patent/DE3785651T2/de not_active Expired - Fee Related
- 1987-12-14 NO NO875209A patent/NO167576C/no unknown
- 1987-12-14 PT PT86356A patent/PT86356B/pt not_active IP Right Cessation
- 1987-12-14 SU SU874355176A patent/SU1731064A3/ru active
- 1987-12-14 ZA ZA879382A patent/ZA879382B/xx unknown
- 1987-12-14 CS CS877675A patent/CS275402B6/cs unknown
- 1987-12-14 AU AU82521/87A patent/AU601529B2/en not_active Ceased
- 1987-12-14 KR KR870014274A patent/KR880007521A/ko not_active Application Discontinuation
- 1987-12-14 DD DD87320503A patent/DD274766A5/de not_active IP Right Cessation
- 1987-12-14 CS CS879161A patent/CS275398B2/cs unknown
- 1987-12-14 PH PH36211A patent/PH24104A/en unknown
- 1987-12-14 CA CA000554258A patent/CA1319143C/en not_active Expired - Fee Related
- 1987-12-14 PL PL1987269462A patent/PL158050B1/pl unknown
- 1987-12-14 HU HU893368A patent/HU200932B/hu not_active IP Right Cessation
- 1987-12-14 PL PL1987277927A patent/PL160322B1/pl unknown
- 1987-12-14 CN CN198787108265A patent/CN87108265A/zh active Pending
- 1987-12-14 EP EP90116634A patent/EP0417560A1/en not_active Withdrawn
- 1987-12-14 HU HU903829A patent/HU207735B/hu not_active IP Right Cessation
- 1987-12-14 FI FI875487A patent/FI875487A/fi not_active Application Discontinuation
- 1987-12-14 MC MC871936A patent/MC1882A1/xx unknown
- 1987-12-14 PL PL1987277926A patent/PL160321B1/pl unknown
- 1987-12-14 ES ES87310951T patent/ES2054693T3/es not_active Expired - Lifetime
- 1987-12-14 DK DK654287A patent/DK654287A/da not_active Application Discontinuation
- 1987-12-14 HU HU893367A patent/HU202112B/hu not_active IP Right Cessation
- 1987-12-14 IE IE930470A patent/IE930470L/xx unknown
-
1988
- 1988-07-05 PH PH37174A patent/PH24870A/en unknown
-
1989
- 1989-05-26 RU SU894614158A patent/RU2036199C1/ru active
-
1990
- 1990-01-16 US US07/465,552 patent/US5079235A/en not_active Expired - Lifetime
- 1990-07-20 IL IL95141A patent/IL95141A0/xx unknown
- 1990-07-26 AU AU59890/90A patent/AU626041B2/en not_active Ceased
- 1990-10-08 JP JP2270325A patent/JPH03141292A/ja active Pending
-
1991
- 1991-10-04 DK DK169991A patent/DK168323B1/da not_active IP Right Cessation
-
1992
- 1992-06-24 MX MX9203216A patent/MX9203216A/es unknown
- 1992-12-18 LV LV920338A patent/LV5273A3/xx unknown
- 1992-12-30 LT LTRP271A patent/LT2064B/xx unknown
-
1993
- 1993-02-27 CN CN93102155A patent/CN1080292A/zh active Pending
-
1994
- 1994-03-31 FI FI941523A patent/FI941523A0/fi not_active Application Discontinuation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK169991A (da) | Antivirale forbindelser | |
DE3679353D1 (de) | Antivirale verbindungen. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHB | Application shelved due to non-payment |