DD267511A5 - Neues Expressionssystem - Google Patents

Neues Expressionssystem Download PDF

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Publication number
DD267511A5
DD267511A5 DD31263288A DD31263288A DD267511A5 DD 267511 A5 DD267511 A5 DD 267511A5 DD 31263288 A DD31263288 A DD 31263288A DD 31263288 A DD31263288 A DD 31263288A DD 267511 A5 DD267511 A5 DD 267511A5
Authority
DD
German Democratic Republic
Prior art keywords
dna
recombinant dna
dna molecule
gene
prepared
Prior art date
Application number
DD31263288A
Other languages
German (de)
English (en)
Inventor
Jutta Heim
Christof Gysler
Jacob Visser
Hermanus C M Kester
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10611694&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DD267511(A5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DD267511A5 publication Critical patent/DD267511A5/de

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/815Protease inhibitors from leeches, e.g. hirudin, eglin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/145Fungal isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
    • C12N9/2408Glucanases acting on alpha -1,4-glucosidic bonds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/645Fungi ; Processes using fungi
    • C12R2001/66Aspergillus
    • C12R2001/685Aspergillus niger

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Image Generation (AREA)
  • Complex Calculations (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hardware Redundancy (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DD31263288A 1987-02-04 1988-02-03 Neues Expressionssystem DD267511A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878702475A GB8702475D0 (en) 1987-02-04 1987-02-04 Expression system

Publications (1)

Publication Number Publication Date
DD267511A5 true DD267511A5 (de) 1989-05-03

Family

ID=10611694

Family Applications (3)

Application Number Title Priority Date Filing Date
DD88327825A DD283837A5 (de) 1987-02-04 1988-02-03 Verfahren zur herstellung eines rekombinanten dna-molekuels
DD31263288A DD267511A5 (de) 1987-02-04 1988-02-03 Neues Expressionssystem
DD88327826A DD283838A5 (de) 1987-02-04 1988-02-03 Verfahren zur herstellung eines polypeptids

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DD88327825A DD283837A5 (de) 1987-02-04 1988-02-03 Verfahren zur herstellung eines rekombinanten dna-molekuels

Family Applications After (1)

Application Number Title Priority Date Filing Date
DD88327826A DD283838A5 (de) 1987-02-04 1988-02-03 Verfahren zur herstellung eines polypeptids

Country Status (23)

Country Link
EP (2) EP0278355B2 (el)
JP (1) JP2633885B2 (el)
KR (1) KR970001116B1 (el)
AT (1) ATE133706T1 (el)
AU (1) AU625773B2 (el)
CA (1) CA1327330C (el)
DD (3) DD283837A5 (el)
DE (1) DE3854947T3 (el)
DK (1) DK175569B1 (el)
ES (1) ES2082746T5 (el)
FI (1) FI105484B (el)
GB (1) GB8702475D0 (el)
GR (1) GR3018863T3 (el)
HU (1) HU214005B (el)
IE (2) IE72506B1 (el)
IL (1) IL85293A (el)
MX (1) MX10286A (el)
NO (1) NO179078C (el)
NZ (1) NZ223392A (el)
PH (1) PH26106A (el)
PT (1) PT86684B (el)
YU (1) YU21688A (el)
ZA (1) ZA88757B (el)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5618920A (en) * 1985-11-01 1997-04-08 Xoma Corporation Modular assembly of antibody genes, antibodies prepared thereby and use
US5576195A (en) * 1985-11-01 1996-11-19 Xoma Corporation Vectors with pectate lyase signal sequence
US5447862A (en) * 1987-02-04 1995-09-05 Ciba-Geigy Corporation Pectin lyase genes of aspergillus niger
AU627443B2 (en) * 1988-01-11 1992-08-27 Xoma Corporation Novel plasmid vector with pectate lyase signal sequence
JP2980626B2 (ja) * 1988-01-11 1999-11-22 ゾーマ・コーポレーション ペクチン酸リアーゼのシグナル配列を含む新規プラスミドベクター
EP0353188B2 (en) * 1988-07-28 2002-03-06 Novartis AG Novel expression system
EP0421919A3 (en) * 1989-09-02 1992-04-15 Ciba-Geigy Ag Polygalacturonase encoding fungal expression system
BR9305957A (pt) * 1992-12-24 1997-10-21 Gist Brocades Nv Clonagem e expressão do gene exo-poligalacturonase do aspergillus
EP0688359A1 (en) * 1993-02-16 1995-12-27 Novo Nordisk A/S An enzyme with pectin lyase activity
US5674728A (en) * 1993-11-03 1997-10-07 Novartis Corporation Aspergillus niger vacuolar aspartyl protease
AU2660397A (en) * 1996-04-05 1997-10-29 Board Of Regents, The University Of Texas System Methods for producing soluble, biologically-active disulfide bond-containing eukaryotic proteins in bacterial cells
US6083715A (en) * 1997-06-09 2000-07-04 Board Of Regents, The University Of Texas System Methods for producing heterologous disulfide bond-containing polypeptides in bacterial cells
US6187580B1 (en) 1997-11-24 2001-02-13 Novo Nordisk A/S Pectate lyases
US6165769A (en) * 1997-11-24 2000-12-26 Novo Nordisk A/S Pectin degrading enzymes from Bacillus licheniformis
WO1999027083A1 (en) * 1997-11-24 1999-06-03 Novo Nordisk A/S PECTIN DEGRADING ENZYMES FROM $i(BACILLUS LICHENIFORMIS)
EP1187925B1 (en) * 1999-06-02 2005-03-30 Novozymes A/S Pectate lyase fusion for expression and secretion of polypeptides
WO2010070146A1 (en) 2008-12-19 2010-06-24 Danisco A/S Process for production of an enzyme product
AU2013302535B2 (en) 2012-08-16 2018-12-06 Bangladesh Jute Research Institute Pectin degrading enzymes from Macrophomina phaseolina and uses thereof
WO2023225459A2 (en) 2022-05-14 2023-11-23 Novozymes A/S Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4885249A (en) 1984-12-05 1989-12-05 Allelix, Inc. Aspergillus niger transformation system
DE3650783T2 (de) 1985-04-15 2004-07-15 Dsm Ip Assets B.V. Verwendung des Glucoamylasepromotors aus Apergillus
EP0353188B2 (en) * 1988-07-28 2002-03-06 Novartis AG Novel expression system

Also Published As

Publication number Publication date
JP2633885B2 (ja) 1997-07-23
DK54588D0 (da) 1988-02-03
IL85293A (en) 1992-12-01
MX10286A (es) 1993-12-01
EP0278355B2 (en) 2002-10-23
PH26106A (en) 1992-02-06
PT86684B (pt) 1992-04-30
NO179078C (no) 1996-07-31
NO880470L (no) 1988-08-05
YU21688A (en) 1991-04-30
AU625773B2 (en) 1992-07-16
KR970001116B1 (en) 1997-01-28
IL85293A0 (en) 1988-07-31
DE3854947T2 (de) 1996-11-14
ES2082746T5 (es) 2003-06-16
DK175569B1 (da) 2004-12-13
FI880439A (fi) 1988-08-05
DE3854947T3 (de) 2003-04-30
GR3018863T3 (en) 1996-05-31
KR880010126A (ko) 1988-10-07
DE3854947D1 (de) 1996-03-14
IE880292L (en) 1988-08-04
HU214005B (hu) 1998-08-28
NO880470D0 (no) 1988-02-03
EP0278355A3 (en) 1989-12-20
GB8702475D0 (en) 1987-03-11
ATE133706T1 (de) 1996-02-15
IE72506B1 (en) 1997-04-23
NZ223392A (en) 1991-05-28
DD283837A5 (de) 1990-10-24
EP0278355A2 (en) 1988-08-17
DD283838A5 (de) 1990-10-24
CA1327330C (en) 1994-03-01
FI105484B (fi) 2000-08-31
ES2082746T3 (es) 1996-04-01
NO179078B (no) 1996-04-22
ZA88757B (en) 1988-08-04
EP0278355B1 (en) 1996-01-31
EP0683228A3 (en) 1996-03-06
EP0683228A2 (en) 1995-11-22
PT86684A (pt) 1988-03-01
DK54588A (da) 1988-08-05
AU1123488A (en) 1988-08-18
JPS63273480A (ja) 1988-11-10
FI880439A0 (fi) 1988-02-01
IE960902L (en) 1988-08-04
HUT46357A (en) 1988-10-28

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