FI880439A - Nytt uttryckningssystem. - Google Patents

Nytt uttryckningssystem. Download PDF

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Publication number
FI880439A
FI880439A FI880439A FI880439A FI880439A FI 880439 A FI880439 A FI 880439A FI 880439 A FI880439 A FI 880439A FI 880439 A FI880439 A FI 880439A FI 880439 A FI880439 A FI 880439A
Authority
FI
Finland
Prior art keywords
hosts
preparation
recombinant dna
dna molecules
vectors
Prior art date
Application number
FI880439A
Other languages
English (en)
Other versions
FI105484B (fi
FI880439A0 (fi
Inventor
Jutta Heim
Christof Gysler
Jacob Visser
Cornelis Maria Kester
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10611694&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI880439(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI880439A0 publication Critical patent/FI880439A0/fi
Publication of FI880439A publication Critical patent/FI880439A/fi
Application granted granted Critical
Publication of FI105484B publication Critical patent/FI105484B/fi

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/815Protease inhibitors from leeches, e.g. hirudin, eglin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/145Fungal isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
    • C12N9/2408Glucanases acting on alpha -1,4-glucosidic bonds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/645Fungi ; Processes using fungi
    • C12R2001/66Aspergillus
    • C12R2001/685Aspergillus niger

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Complex Calculations (AREA)
  • Image Generation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Multi-Process Working Machines And Systems (AREA)
FI880439A 1987-02-04 1988-02-01 Pektiinilyaasin ilmentämisjärjestelmää koodittava yhdistelmä-DNA-molekyyli FI105484B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878702475A GB8702475D0 (en) 1987-02-04 1987-02-04 Expression system
GB8702475 1987-02-04

Publications (3)

Publication Number Publication Date
FI880439A0 FI880439A0 (fi) 1988-02-01
FI880439A true FI880439A (fi) 1988-08-05
FI105484B FI105484B (fi) 2000-08-31

Family

ID=10611694

Family Applications (1)

Application Number Title Priority Date Filing Date
FI880439A FI105484B (fi) 1987-02-04 1988-02-01 Pektiinilyaasin ilmentämisjärjestelmää koodittava yhdistelmä-DNA-molekyyli

Country Status (23)

Country Link
EP (2) EP0278355B2 (fi)
JP (1) JP2633885B2 (fi)
KR (1) KR970001116B1 (fi)
AT (1) ATE133706T1 (fi)
AU (1) AU625773B2 (fi)
CA (1) CA1327330C (fi)
DD (3) DD267511A5 (fi)
DE (1) DE3854947T3 (fi)
DK (1) DK175569B1 (fi)
ES (1) ES2082746T5 (fi)
FI (1) FI105484B (fi)
GB (1) GB8702475D0 (fi)
GR (1) GR3018863T3 (fi)
HU (1) HU214005B (fi)
IE (2) IE960902L (fi)
IL (1) IL85293A (fi)
MX (1) MX10286A (fi)
NO (1) NO179078C (fi)
NZ (1) NZ223392A (fi)
PH (1) PH26106A (fi)
PT (1) PT86684B (fi)
YU (1) YU21688A (fi)
ZA (1) ZA88757B (fi)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5618920A (en) * 1985-11-01 1997-04-08 Xoma Corporation Modular assembly of antibody genes, antibodies prepared thereby and use
US5576195A (en) * 1985-11-01 1996-11-19 Xoma Corporation Vectors with pectate lyase signal sequence
US5447862A (en) * 1987-02-04 1995-09-05 Ciba-Geigy Corporation Pectin lyase genes of aspergillus niger
AU627443B2 (en) * 1988-01-11 1992-08-27 Xoma Corporation Novel plasmid vector with pectate lyase signal sequence
DE68926882T2 (de) * 1988-01-11 1997-02-13 Xoma Corp Plasmidvektor mit pectatlyase-signalsequenz
DE68913846T3 (de) * 1988-07-28 2002-10-02 Novartis Ag Expressionssystem.
EP0421919A3 (en) * 1989-09-02 1992-04-15 Ciba-Geigy Ag Polygalacturonase encoding fungal expression system
US5624834A (en) * 1992-12-24 1997-04-29 Gist-Brocades, B.V. Cloning and expression of the exo-polygalacturonase gene from aspergillus
WO1994021786A1 (en) * 1993-02-16 1994-09-29 Novo Nordisk A/S An enzyme with pectin lyase activity
US5674728A (en) * 1993-11-03 1997-10-07 Novartis Corporation Aspergillus niger vacuolar aspartyl protease
US6027888A (en) * 1996-04-05 2000-02-22 Board Of Regents, The University Of Texas System Methods for producing soluble, biologically-active disulfide-bond containing eukaryotic proteins in bacterial cells
US6083715A (en) * 1997-06-09 2000-07-04 Board Of Regents, The University Of Texas System Methods for producing heterologous disulfide bond-containing polypeptides in bacterial cells
WO1999027083A1 (en) * 1997-11-24 1999-06-03 Novo Nordisk A/S PECTIN DEGRADING ENZYMES FROM $i(BACILLUS LICHENIFORMIS)
US6187580B1 (en) 1997-11-24 2001-02-13 Novo Nordisk A/S Pectate lyases
US6165769A (en) * 1997-11-24 2000-12-26 Novo Nordisk A/S Pectin degrading enzymes from Bacillus licheniformis
EP1187925B1 (en) * 1999-06-02 2005-03-30 Novozymes A/S Pectate lyase fusion for expression and secretion of polypeptides
US8765442B2 (en) 2008-12-19 2014-07-01 Dupont Nutrition Biosciences Aps Process for production of an enzyme product
TR201809053T4 (tr) 2012-08-16 2018-07-23 Bangladesh Jute Res Institute Macrophomina phaseolina'dan elde edilen pektin parçalama enzimleri ve bunların kullanımları.
WO2023225459A2 (en) 2022-05-14 2023-11-23 Novozymes A/S Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4885249A (en) 1984-12-05 1989-12-05 Allelix, Inc. Aspergillus niger transformation system
ATE161881T1 (de) 1985-04-15 1998-01-15 Gist Brocades Nv Verwendung von promotoren von filamentösen pilzen
DE68913846T3 (de) * 1988-07-28 2002-10-02 Novartis Ag Expressionssystem.

Also Published As

Publication number Publication date
HU214005B (hu) 1998-08-28
KR880010126A (ko) 1988-10-07
PH26106A (en) 1992-02-06
AU1123488A (en) 1988-08-18
FI105484B (fi) 2000-08-31
ZA88757B (en) 1988-08-04
GR3018863T3 (en) 1996-05-31
JP2633885B2 (ja) 1997-07-23
NO179078C (no) 1996-07-31
ATE133706T1 (de) 1996-02-15
IL85293A (en) 1992-12-01
DD267511A5 (de) 1989-05-03
NZ223392A (en) 1991-05-28
EP0278355B1 (en) 1996-01-31
DD283837A5 (de) 1990-10-24
CA1327330C (en) 1994-03-01
DE3854947T2 (de) 1996-11-14
MX10286A (es) 1993-12-01
YU21688A (en) 1991-04-30
EP0278355B2 (en) 2002-10-23
PT86684A (pt) 1988-03-01
DK54588A (da) 1988-08-05
DK175569B1 (da) 2004-12-13
IL85293A0 (en) 1988-07-31
EP0278355A3 (en) 1989-12-20
EP0278355A2 (en) 1988-08-17
KR970001116B1 (en) 1997-01-28
ES2082746T5 (es) 2003-06-16
NO880470D0 (no) 1988-02-03
AU625773B2 (en) 1992-07-16
PT86684B (pt) 1992-04-30
DE3854947D1 (de) 1996-03-14
NO880470L (no) 1988-08-05
DE3854947T3 (de) 2003-04-30
DD283838A5 (de) 1990-10-24
IE880292L (en) 1988-08-04
EP0683228A2 (en) 1995-11-22
IE72506B1 (en) 1997-04-23
JPS63273480A (ja) 1988-11-10
ES2082746T3 (es) 1996-04-01
FI880439A0 (fi) 1988-02-01
NO179078B (no) 1996-04-22
IE960902L (en) 1988-08-04
GB8702475D0 (en) 1987-03-11
DK54588D0 (da) 1988-02-03
EP0683228A3 (en) 1996-03-06
HUT46357A (en) 1988-10-28

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Owner name: NOVARTIS AG

FG Patent granted

Owner name: NOVARTIS AG