DD264429A5 - Verfahren zur herstellung von carbocyclisch und heterocyclisch anellierten dihydropyridinen - Google Patents

Verfahren zur herstellung von carbocyclisch und heterocyclisch anellierten dihydropyridinen Download PDF

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Publication number
DD264429A5
DD264429A5 DD87304137A DD30413787A DD264429A5 DD 264429 A5 DD264429 A5 DD 264429A5 DD 87304137 A DD87304137 A DD 87304137A DD 30413787 A DD30413787 A DD 30413787A DD 264429 A5 DD264429 A5 DD 264429A5
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DD
German Democratic Republic
Prior art keywords
alkyl
hydrogen
substituted
hydroxy
phenyl
Prior art date
Application number
DD87304137A
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German (de)
English (en)
Inventor
Walter Loesel
Gerd Schnorrenberg
Otto Roos
Dietrich Arndts
Ilse Streller
Werner Traunecker
Original Assignee
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Application filed by �������@������������@��k�� filed Critical �������@������������@��k��
Publication of DD264429A5 publication Critical patent/DD264429A5/de

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18Aralkyl radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DD87304137A 1986-06-26 1987-06-24 Verfahren zur herstellung von carbocyclisch und heterocyclisch anellierten dihydropyridinen DD264429A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863621413 DE3621413A1 (de) 1986-06-26 1986-06-26 Verwendung carbocyclisch und heterocyclisch annelierter dihydropyridine als cardioprotektive mittel sowie neue heterocyclisch und carbocyclisch anellierte dihydropyridine, verfahren zu deren herstellung und zwischenstufen fuer deren herstellung

Publications (1)

Publication Number Publication Date
DD264429A5 true DD264429A5 (de) 1989-02-01

Family

ID=6303756

Family Applications (1)

Application Number Title Priority Date Filing Date
DD87304137A DD264429A5 (de) 1986-06-26 1987-06-24 Verfahren zur herstellung von carbocyclisch und heterocyclisch anellierten dihydropyridinen

Country Status (18)

Country Link
EP (1) EP0251194B1 (hu)
JP (1) JPS63258458A (hu)
KR (2) KR890000480A (hu)
AU (1) AU598558B2 (hu)
DD (1) DD264429A5 (hu)
DE (2) DE3621413A1 (hu)
DK (1) DK323887A (hu)
ES (1) ES2053471T3 (hu)
FI (1) FI872827A (hu)
GR (1) GR3007545T3 (hu)
HU (1) HU203752B (hu)
IE (1) IE59546B1 (hu)
IL (1) IL82995A0 (hu)
NO (1) NO872672L (hu)
PL (1) PL159840B1 (hu)
PT (1) PT85169B (hu)
YU (1) YU46216B (hu)
ZA (1) ZA874587B (hu)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2623810B2 (fr) * 1987-02-17 1992-01-24 Sanofi Sa Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant
IL86131A0 (en) * 1987-04-24 1988-11-15 Boehringer Ingelheim Kg Benzo-and thieno-3,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
DE3827727A1 (de) * 1988-08-16 1990-02-22 Boehringer Ingelheim Kg Anellierte tetrahydropyridinessigsaeurederivate, verfahren zu deren herstellung und verwendung solcher verbindungen zur kardioprotektion
GB8921304D0 (en) * 1989-09-20 1989-11-08 Wyeth John & Brother Ltd New method of treatment and heterocyclic compounds used therein
DE9017900U1 (de) 1990-12-22 1993-01-28 Boehringer Ingelheim Kg, 55218 Ingelheim 3,4-Dihydro-1-benzyl-6,7-dimethoxy-α- [di-2-(2,3,4-trimethoxyphenyl)ethyl] aminocarbonyl-isochinolin
CN1056832C (zh) * 1992-06-22 2000-09-27 贝林格尔·英格海姆公司 稠合二氢吡啶衍生物及其制法和含有其的药物组合物
CA2138788A1 (en) * 1992-06-22 1994-01-06 Dietrich Arndts Ring-closed dihydropyridines and their use in the preparation of pharmaceutical compositions
DE4343683A1 (de) * 1993-12-21 1995-06-22 Boehringer Ingelheim Kg Anellierte Dihydropyridine und deren Verwendung für die Herstellung von pharmazeutischen Zubereitungen
FR2724384B1 (fr) * 1994-09-14 1999-04-16 Cemaf Nouveaux derives de la 3,4-dihydro beta-carboline agonistes de la melatonine, leur procede de preparation et leur utilisation a titre de medicament

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2417512A1 (fr) * 1978-02-17 1979-09-14 Parcor Thieno (3,2-c) et thieno (2,3-c) pyridines, leur procede de preparation et leur application en therapeutique
DE3013906A1 (de) * 1980-04-11 1981-10-15 C.H. Boehringer Sohn, 6507 Ingelheim Substituierte (alpha) -aminocarbonyl-l-benzyl-3,4-dihydro-isochinoline, verfahren zu deren herstellung und deren verwendung
DE3309596A1 (de) * 1982-08-05 1984-04-05 Basf Ag, 6700 Ludwigshafen 2-substituierte 1-(3'-aminoalkyl)-1,2,3,4-tetrahydro-ss-carboline, ihre herstellung und verwendung als arzneimittel

Also Published As

Publication number Publication date
IL82995A0 (en) 1987-12-20
PT85169A (de) 1987-07-01
DK323887A (da) 1987-12-27
EP0251194B1 (de) 1993-03-31
GR3007545T3 (hu) 1993-08-31
ES2053471T3 (es) 1994-08-01
IE871689L (en) 1987-12-26
EP0251194A1 (de) 1988-01-07
PL159840B1 (pl) 1993-01-29
ZA874587B (en) 1989-02-22
DK323887D0 (da) 1987-06-25
PL266416A1 (en) 1988-09-01
HUT47932A (en) 1989-04-28
NO872672L (no) 1987-12-28
AU7477587A (en) 1988-01-07
PT85169B (pt) 1990-03-30
YU46216B (sh) 1993-05-28
KR930006639B1 (ko) 1993-07-22
KR890002144A (ko) 1989-04-08
JPS63258458A (ja) 1988-10-25
AU598558B2 (en) 1990-06-28
IE59546B1 (en) 1994-03-09
HU203752B (en) 1991-09-30
FI872827A0 (fi) 1987-06-26
FI872827A (fi) 1987-12-27
DE3621413A1 (de) 1988-01-07
KR890000480A (ko) 1989-03-14
DE3785093D1 (de) 1993-05-06
NO872672D0 (no) 1987-06-25
YU119887A (en) 1988-10-31

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