DD216012A5 - Verfahren zur herstellung von aryl-thiazolidindion-derivaten - Google Patents

Verfahren zur herstellung von aryl-thiazolidindion-derivaten Download PDF

Info

Publication number
DD216012A5
DD216012A5 DD84259419A DD25941984A DD216012A5 DD 216012 A5 DD216012 A5 DD 216012A5 DD 84259419 A DD84259419 A DD 84259419A DD 25941984 A DD25941984 A DD 25941984A DD 216012 A5 DD216012 A5 DD 216012A5
Authority
DD
German Democratic Republic
Prior art keywords
meaning
item
methyl
carried out
hydrogen
Prior art date
Application number
DD84259419A
Other languages
German (de)
English (en)
Inventor
Rodney C Schnur
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DD216012A5 publication Critical patent/DD216012A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/20Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/225Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/513Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an etherified hydroxyl group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34Oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Paints Or Removers (AREA)
DD84259419A 1983-01-17 1984-01-16 Verfahren zur herstellung von aryl-thiazolidindion-derivaten DD216012A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45868483A 1983-01-17 1983-01-17

Publications (1)

Publication Number Publication Date
DD216012A5 true DD216012A5 (de) 1984-11-28

Family

ID=23821708

Family Applications (1)

Application Number Title Priority Date Filing Date
DD84259419A DD216012A5 (de) 1983-01-17 1984-01-16 Verfahren zur herstellung von aryl-thiazolidindion-derivaten

Country Status (26)

Country Link
EP (1) EP0117035B1 (pt)
JP (1) JPS59137474A (pt)
KR (1) KR870001267B1 (pt)
AT (1) ATE45574T1 (pt)
AU (1) AU539921B2 (pt)
CA (1) CA1233470A (pt)
CS (1) CS241149B2 (pt)
DD (1) DD216012A5 (pt)
DE (1) DE3479419D1 (pt)
DK (1) DK17984A (pt)
EG (1) EG16563A (pt)
ES (1) ES8506663A1 (pt)
FI (1) FI840155A (pt)
GR (1) GR79763B (pt)
GT (1) GT198400006A (pt)
HU (1) HU191265B (pt)
IE (1) IE56842B1 (pt)
IL (1) IL70690A (pt)
NO (1) NO162462C (pt)
NZ (1) NZ206845A (pt)
PH (1) PH18882A (pt)
PL (1) PL142152B1 (pt)
PT (1) PT77958B (pt)
SU (1) SU1189341A3 (pt)
YU (1) YU43336B (pt)
ZA (1) ZA84305B (pt)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0397453A1 (en) * 1989-05-09 1990-11-14 Beecham Group p.l.c. Novel bis-2,4-dioxothiazolidines

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986007056A1 (en) 1985-05-21 1986-12-04 Pfizer Inc. Hypoglycemic thiazolidinediones
JPH04210683A (ja) * 1990-12-06 1992-07-31 Terumo Corp チアゾリジン−2,4−ジオン誘導体およびこれを含有する糖尿病合併症治療薬
JP3053490B2 (ja) * 1991-02-25 2000-06-19 杏林製薬株式会社 チアゾリジン−2,4−ジオン誘導体とその塩及び製造法
CA3053956C (en) * 2017-03-03 2024-04-23 Gilead Sciences, Inc. Processes for preparing acc inhibitors and solid forms thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2263296A1 (de) * 1972-12-23 1974-06-27 Bayer Ag 4-alkyl-thiazol-2-one, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
JPS56104876A (en) * 1980-01-24 1981-08-20 Takeda Chem Ind Ltd Thiazolidine derivative
JPS5728075A (en) * 1980-07-29 1982-02-15 Takeda Chem Ind Ltd Thiazolidine derivative
AU6610081A (en) * 1980-01-24 1981-07-30 Senju Pharmaceutical Co., Ltd. Thiazolidine derivatives
JPS5728073A (en) * 1980-07-29 1982-02-15 Takeda Chem Ind Ltd Inhibitor for aldose reducing enzyme
JPS57123175A (en) * 1981-01-26 1982-07-31 Takeda Chem Ind Ltd Preparation of thiazolidine derivative

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0397453A1 (en) * 1989-05-09 1990-11-14 Beecham Group p.l.c. Novel bis-2,4-dioxothiazolidines

Also Published As

Publication number Publication date
IE56842B1 (en) 1992-01-01
GR79763B (pt) 1984-10-31
PH18882A (en) 1985-10-22
AU539921B2 (en) 1984-10-25
CS38584A2 (en) 1985-07-16
IL70690A0 (en) 1984-04-30
GT198400006A (es) 1985-07-06
PL245745A1 (en) 1984-10-22
CS241149B2 (en) 1986-03-13
SU1189341A3 (ru) 1985-10-30
EG16563A (en) 1989-06-30
DK17984D0 (da) 1984-01-16
PL142152B1 (en) 1987-09-30
NZ206845A (en) 1986-09-10
PT77958B (en) 1986-06-18
DK17984A (da) 1984-07-18
IE840079L (en) 1984-07-17
JPH0329073B2 (pt) 1991-04-23
KR840007223A (ko) 1984-12-06
ZA84305B (en) 1985-08-28
AU2328784A (en) 1984-07-19
NO162462B (no) 1989-09-25
FI840155A (fi) 1984-07-18
YU43336B (en) 1989-06-30
DE3479419D1 (en) 1989-09-21
ATE45574T1 (de) 1989-09-15
JPS59137474A (ja) 1984-08-07
EP0117035A2 (en) 1984-08-29
YU6184A (en) 1986-06-30
EP0117035B1 (en) 1989-08-16
CA1233470A (en) 1988-03-01
PT77958A (en) 1984-02-01
ES528887A0 (es) 1985-08-01
EP0117035A3 (en) 1987-01-14
NO840144L (no) 1984-07-18
FI840155A0 (fi) 1984-01-16
NO162462C (no) 1990-01-03
HU191265B (en) 1987-01-28
ES8506663A1 (es) 1985-08-01
IL70690A (en) 1989-01-31
KR870001267B1 (ko) 1987-06-30

Similar Documents

Publication Publication Date Title
DE2933441C2 (de) Spiro-[4H-2,3-dihydrobenzopyran(4,5')oxazolidin]-2',4'-dione und solche Verbindungen enthaltende Arzneimittel
DE2733868A1 (de) Neue 1,2,4,5-tetrahydro-3h-2-benzazepin-3-one, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
US4617312A (en) Aldose reductase inhibiting 5-(2-alkoxyphenyl) thiazolidinediones
DE69018876T2 (de) Pyridazinon-Derivate.
DE2746244A1 (de) Spiro-hydantoin-verbindungen und ihre verwendung
DE69204041T2 (de) Thiazolidinverbindeungen, deren Herstellung und therapeutische Verwendung.
DE2516554A1 (de) Thienyl- und thiaethylverbindungen
DE69225123T2 (de) Thiazolidinederivate, die eine Quinone-Gruppe enthalten, ihre Herstellung und therapeutische Anwendung
DE2816785A1 (de) Neue cinnamoyl-piperazine und homo-piperazine, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
EP0185909B1 (de) 5-Alkyl-1-phenyl-2-piperazinoalkylpyrazolin-3-on-Verbindungen sowie Verfahren und Zwischenprodukte zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2814321A1 (de) Interphenylen-8-aza-9-dioxothia- 11,12-secoprostaglandine
DE3784835T2 (de) Chinoxalinon-derivate.
DD216012A5 (de) Verfahren zur herstellung von aryl-thiazolidindion-derivaten
DE3813531A1 (de) Neue 2-aminoalkyl-4-benzyl-1-(2h)-phthalazinon-derivate
EP0075140B1 (de) Tricyclische Thiazolyloxamidsäuren und Derivate, Verfahren zu ihrer Herstellung und diese enthaltende therapeutische Mittel
EP0072960B1 (de) 1,5-Diphenylpyrazolin-3-on-Verbindungen sowie Verfahren und Zwischenprodukte zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DD251972A5 (de) Verfahren zur herstellung von spiroimidazolidinen
CH651302A5 (de) In 6-stellung substituierte 6h-dibenzo-(b,d)-pyranderivate und verfahren zu ihrer herstellung.
DE69503890T2 (de) Benzisothiazol-derivate als inhibitoren der 5-lipoxygenase biosynthese
DE1670248A1 (de) Verfahren zur Herstellung von substituierten Isothiazolen
DE2442210A1 (de) N-heterocyclische pulvinsaeureamide und arzneimittel
DE2814168A1 (de) Neue 1- eckige klammer auf 3-(3,4,5- trimethoxyphenoxy)-2-hydroxypropyl eckige klammer zu -4-aryl-piperazin-derivate und verfahren zu ihrer herstellung
DE69101937T2 (de) Antiallergische und antiinflammatorische Mittel auf der Basis von Benzoquinon.
DE3726633A1 (de) Neue 1,2-diamino-verbindungen, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
EP0594036A1 (de) Arylalkoxythiocumarine, Verfahren zu ihrer Herstellung und diese enthaltende therapeutische Mittel