DD157345A5 - Ein verfahren zur herstellung einer antibiotischen substanz - Google Patents

Ein verfahren zur herstellung einer antibiotischen substanz Download PDF

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Publication number
DD157345A5
DD157345A5 DD80220468A DD22046880A DD157345A5 DD 157345 A5 DD157345 A5 DD 157345A5 DD 80220468 A DD80220468 A DD 80220468A DD 22046880 A DD22046880 A DD 22046880A DD 157345 A5 DD157345 A5 DD 157345A5
Authority
DD
German Democratic Republic
Prior art keywords
substance
streptomyces
spectrum
active fraction
strain
Prior art date
Application number
DD80220468A
Other languages
German (de)
English (en)
Inventor
Masahito Nakayama
Akio Iwasaki
Shigeru Kimura
Sohei Tanabe
Toshimi Mizoguchi
Akira Murakami
Isamu Watanabe
Masao Okuchi
Hisakatsu Ito
Toshihito Mori
Original Assignee
Kowa Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP4651679A external-priority patent/JPS55139380A/ja
Priority claimed from JP11913979A external-priority patent/JPS5643284A/ja
Application filed by Kowa Co filed Critical Kowa Co
Publication of DD157345A5 publication Critical patent/DD157345A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
    • C12P17/184—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system containing a beta-lactam ring, e.g. thienamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DD80220468A 1979-04-16 1980-04-15 Ein verfahren zur herstellung einer antibiotischen substanz DD157345A5 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4651679A JPS55139380A (en) 1979-04-16 1979-04-16 Antibiotic and its preparation
JP11913979A JPS5643284A (en) 1979-09-17 1979-09-17 Antibiotic and its preparation

Publications (1)

Publication Number Publication Date
DD157345A5 true DD157345A5 (de) 1982-11-03

Family

ID=26386608

Family Applications (1)

Application Number Title Priority Date Filing Date
DD80220468A DD157345A5 (de) 1979-04-16 1980-04-15 Ein verfahren zur herstellung einer antibiotischen substanz

Country Status (12)

Country Link
US (1) US4530791A (da)
AT (1) AT371146B (da)
DD (1) DD157345A5 (da)
DE (1) DE3014434A1 (da)
DK (1) DK161880A (da)
ES (1) ES8104829A1 (da)
FR (1) FR2454441A1 (da)
GB (1) GB2047700B (da)
IT (1) IT1194646B (da)
NL (1) NL8002210A (da)
PT (1) PT71091A (da)
SE (1) SE8002827L (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU534530B2 (en) * 1979-02-02 1984-02-02 Takeda Chemical Industries Ltd. 5-aza-(3.2.0)-heptane derivatives
US4409147A (en) * 1980-03-10 1983-10-11 Takeda Chemical Industries, Ltd. Carbapenem compounds and their production
US4497742A (en) * 1981-03-04 1985-02-05 Takeda Chemical Industries, Ltd. Isomerization of β-lactam compounds
EP0074599A1 (en) * 1981-09-09 1983-03-23 Takeda Chemical Industries, Ltd. 5,6-cis-Carbapenem derivatives, their production and use
WO1983002614A1 (en) * 1982-02-02 1983-08-04 Takeda Chemical Industries Ltd 5,6-cis-carbapenem-3-carboxylic acid derivatives and process for their preparation
WO1983000867A1 (en) * 1981-09-09 1983-03-17 Takeda Chemical Industries Ltd 5,6-cis-carbapenem-3-carboxylic acid derivatives and process for their preparation

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4172129A (en) * 1974-03-28 1979-10-23 Beecham Group Limited Antibiotics
GB1467413A (en) * 1974-03-28 1977-03-16 Beecham Group Ltd Antibiotics
GB1489235A (en) * 1974-03-28 1977-10-19 Beecham Group Ltd Antibiotics
GB1483142A (en) * 1975-03-15 1977-08-17 Beecham Group Ltd Streptomycetal antibiotic
GB1577725A (en) * 1976-06-30 1980-10-29 Beecham Group Ltd Azetidinone derivatives
GB1531141A (en) * 1976-08-17 1978-11-01 Beecham Group Ltd Beta-lactam antibiotics
NL7712091A (nl) * 1976-11-17 1978-05-19 Merck & Co Inc Werkwijze ter bereiding van een nieuw antibiotisch middel.
EP0002564B1 (en) * 1977-11-12 1984-06-20 Beecham Group Plc Derivatives of 7-oxo-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylic acid, their preparation, pharmaceutical compositions containing them and intermediates
US4211707A (en) * 1978-08-10 1980-07-08 Merck & Co., Inc. Process for hydrolytically cleaving O-sulfo thienamycins
EP0008885B1 (en) * 1978-09-09 1983-11-30 Beecham Group Plc Beta-lactam compounds, their preparation and use
US4232036A (en) * 1978-10-24 1980-11-04 Merck & Co., Inc. 6-, 1- and 2-Substituted-1-carbadethiapen-2-em-3-carboxylic acids
AU534530B2 (en) * 1979-02-02 1984-02-02 Takeda Chemical Industries Ltd. 5-aza-(3.2.0)-heptane derivatives

Also Published As

Publication number Publication date
ES490574A0 (es) 1981-04-16
NL8002210A (nl) 1980-10-20
US4530791A (en) 1985-07-23
GB2047700B (en) 1983-06-15
IT1194646B (it) 1988-09-22
PT71091A (en) 1980-05-01
IT8021374A0 (it) 1980-04-15
DE3014434A1 (de) 1981-01-29
SE8002827L (sv) 1980-10-17
ATA205080A (de) 1982-10-15
ES8104829A1 (es) 1981-04-16
DK161880A (da) 1980-10-17
AT371146B (de) 1983-06-10
GB2047700A (en) 1980-12-03
FR2454441A1 (fr) 1980-11-14
FR2454441B1 (da) 1984-10-26

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