FR2454441A1 - Nouvel antibiotique et son procede de preparation a partir de souches appartenant au genre streptomyces - Google Patents

Nouvel antibiotique et son procede de preparation a partir de souches appartenant au genre streptomyces

Info

Publication number
FR2454441A1
FR2454441A1 FR8008325A FR8008325A FR2454441A1 FR 2454441 A1 FR2454441 A1 FR 2454441A1 FR 8008325 A FR8008325 A FR 8008325A FR 8008325 A FR8008325 A FR 8008325A FR 2454441 A1 FR2454441 A1 FR 2454441A1
Authority
FR
France
Prior art keywords
preparation
genus streptomyces
strains belonging
novel antibiotic
antibiotic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8008325A
Other languages
English (en)
Other versions
FR2454441B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kowa Co Ltd
Original Assignee
Kowa Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP4651679A external-priority patent/JPS55139380A/ja
Priority claimed from JP11913979A external-priority patent/JPS5643284A/ja
Application filed by Kowa Co Ltd filed Critical Kowa Co Ltd
Publication of FR2454441A1 publication Critical patent/FR2454441A1/fr
Application granted granted Critical
Publication of FR2454441B1 publication Critical patent/FR2454441B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
    • C12P17/184—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system containing a beta-lactam ring, e.g. thienamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

NOUVEL ANTIBIOTIQUE. IL REPOND A LA FORMULE: (CF DESSIN DANS BOPI) OU R H OU SOH. APPLICATION THERAPEUTIQUE.
FR8008325A 1979-04-16 1980-04-14 Nouvel antibiotique et son procede de preparation a partir de souches appartenant au genre streptomyces Granted FR2454441A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4651679A JPS55139380A (en) 1979-04-16 1979-04-16 Antibiotic and its preparation
JP11913979A JPS5643284A (en) 1979-09-17 1979-09-17 Antibiotic and its preparation

Publications (2)

Publication Number Publication Date
FR2454441A1 true FR2454441A1 (fr) 1980-11-14
FR2454441B1 FR2454441B1 (fr) 1984-10-26

Family

ID=26386608

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8008325A Granted FR2454441A1 (fr) 1979-04-16 1980-04-14 Nouvel antibiotique et son procede de preparation a partir de souches appartenant au genre streptomyces

Country Status (12)

Country Link
US (1) US4530791A (fr)
AT (1) AT371146B (fr)
DD (1) DD157345A5 (fr)
DE (1) DE3014434A1 (fr)
DK (1) DK161880A (fr)
ES (1) ES490574A0 (fr)
FR (1) FR2454441A1 (fr)
GB (1) GB2047700B (fr)
IT (1) IT1194646B (fr)
NL (1) NL8002210A (fr)
PT (1) PT71091A (fr)
SE (1) SE8002827L (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2477546A1 (fr) * 1980-03-10 1981-09-11 Takeda Chemical Industries Ltd Composes carbapenemes et leurs procedes de preparation

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU534530B2 (en) * 1979-02-02 1984-02-02 Takeda Chemical Industries Ltd. 5-aza-(3.2.0)-heptane derivatives
US4497742A (en) * 1981-03-04 1985-02-05 Takeda Chemical Industries, Ltd. Isomerization of β-lactam compounds
WO1983002614A1 (fr) * 1982-02-02 1983-08-04 Takeda Chemical Industries Ltd Derives de l'acide 5,6-cis-carbapenem-3-carboxylique et leur procede de preparation
WO1983000867A1 (fr) * 1981-09-09 1983-03-17 Takeda Chemical Industries Ltd Derives d'acide 5,6-cis-carbapeneme-3-carboxylique et leur procede de preparation
EP0074599A1 (fr) * 1981-09-09 1983-03-23 Takeda Chemical Industries, Ltd. Dérivés de 5,6-cis-carbapénème, leurs préparation et utilisation

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1467413A (en) * 1974-03-28 1977-03-16 Beecham Group Ltd Antibiotics
DE2751260A1 (de) * 1976-11-17 1978-05-24 Merck & Co Inc Antibiotikum 890 a tief 9
EP0008885A1 (fr) * 1978-09-09 1980-03-19 Beecham Group Plc Composés de bêta-lactame, leur préparation et application

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1489235A (en) * 1974-03-28 1977-10-19 Beecham Group Ltd Antibiotics
US4172129A (en) * 1974-03-28 1979-10-23 Beecham Group Limited Antibiotics
GB1483142A (en) * 1975-03-15 1977-08-17 Beecham Group Ltd Streptomycetal antibiotic
GB1577725A (en) * 1976-06-30 1980-10-29 Beecham Group Ltd Azetidinone derivatives
GB1531141A (en) * 1976-08-17 1978-11-01 Beecham Group Ltd Beta-lactam antibiotics
EP0002564B1 (fr) * 1977-11-12 1984-06-20 Beecham Group Plc Dérivés de l'acide 7-oxo-1-azabicyclo-(3.2.0)-hept-2-ène-2-carboxylique, leur préparation, compositions pharmaceutiques les contenant et produits intermédiaires
US4211707A (en) * 1978-08-10 1980-07-08 Merck & Co., Inc. Process for hydrolytically cleaving O-sulfo thienamycins
US4232036A (en) * 1978-10-24 1980-11-04 Merck & Co., Inc. 6-, 1- and 2-Substituted-1-carbadethiapen-2-em-3-carboxylic acids
AU534530B2 (en) * 1979-02-02 1984-02-02 Takeda Chemical Industries Ltd. 5-aza-(3.2.0)-heptane derivatives

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1467413A (en) * 1974-03-28 1977-03-16 Beecham Group Ltd Antibiotics
DE2751260A1 (de) * 1976-11-17 1978-05-24 Merck & Co Inc Antibiotikum 890 a tief 9
EP0008885A1 (fr) * 1978-09-09 1980-03-19 Beecham Group Plc Composés de bêta-lactame, leur préparation et application

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2477546A1 (fr) * 1980-03-10 1981-09-11 Takeda Chemical Industries Ltd Composes carbapenemes et leurs procedes de preparation

Also Published As

Publication number Publication date
ES8104829A1 (es) 1981-04-16
NL8002210A (nl) 1980-10-20
GB2047700A (en) 1980-12-03
DD157345A5 (de) 1982-11-03
IT8021374A0 (it) 1980-04-15
DK161880A (da) 1980-10-17
GB2047700B (en) 1983-06-15
DE3014434A1 (de) 1981-01-29
ES490574A0 (es) 1981-04-16
US4530791A (en) 1985-07-23
PT71091A (en) 1980-05-01
SE8002827L (sv) 1980-10-17
FR2454441B1 (fr) 1984-10-26
IT1194646B (it) 1988-09-22
ATA205080A (de) 1982-10-15
AT371146B (de) 1983-06-10

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