DD157190A5 - Verfahren zur herstellung neuer sulfonamide - Google Patents
Verfahren zur herstellung neuer sulfonamide Download PDFInfo
- Publication number
- DD157190A5 DD157190A5 DD81226847A DD22684781A DD157190A5 DD 157190 A5 DD157190 A5 DD 157190A5 DD 81226847 A DD81226847 A DD 81226847A DD 22684781 A DD22684781 A DD 22684781A DD 157190 A5 DD157190 A5 DD 157190A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- acid
- ethyl
- group
- general formula
- yield
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Devices That Are Associated With Refrigeration Equipment (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19803000377 DE3000377A1 (de) | 1980-01-07 | 1980-01-07 | Neue sulfonamide, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
DD157190A5 true DD157190A5 (de) | 1982-10-20 |
Family
ID=6091629
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DD81226847A DD157190A5 (de) | 1980-01-07 | 1981-01-06 | Verfahren zur herstellung neuer sulfonamide |
Country Status (22)
Country | Link |
---|---|
US (1) | US4443477A (fr) |
EP (1) | EP0031954B1 (fr) |
JP (1) | JPS56100757A (fr) |
AT (1) | ATE6641T1 (fr) |
AU (1) | AU538993B2 (fr) |
CA (1) | CA1241341A (fr) |
CS (1) | CS238611B2 (fr) |
DD (1) | DD157190A5 (fr) |
DE (2) | DE3000377A1 (fr) |
ES (1) | ES498308A0 (fr) |
FI (1) | FI73667C (fr) |
GR (1) | GR72486B (fr) |
HK (1) | HK68887A (fr) |
IE (1) | IE50657B1 (fr) |
IL (1) | IL61834A (fr) |
PH (1) | PH18739A (fr) |
PL (1) | PL127050B1 (fr) |
PT (1) | PT72305B (fr) |
SG (1) | SG2387G (fr) |
SU (1) | SU1088664A3 (fr) |
YU (1) | YU42995B (fr) |
ZA (1) | ZA8132B (fr) |
Families Citing this family (62)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4401663A (en) * | 1981-06-30 | 1983-08-30 | The Procter & Gamble Company | Novel sulfonamide derivatives |
AU567140B2 (en) * | 1984-01-06 | 1987-11-12 | Shionogi & Co., Ltd. | Sulphonamido-benzamide derivatives |
EP0194548A3 (fr) * | 1985-03-12 | 1988-08-17 | Dr. Karl Thomae GmbH | Composés sulfonylaminoéthyl, médicament contenant ces composés et leur procédé de préparation |
DE3535167A1 (de) * | 1985-10-02 | 1987-04-09 | Boehringer Mannheim Gmbh | Neue sulfonyl-phenyl(alkyl)amine, verfahren zu ihrer herstellung sowie arzneimittel |
US4689182A (en) * | 1985-12-20 | 1987-08-25 | Warner-Lambert Company | Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity |
FR2598412B1 (fr) * | 1986-03-12 | 1988-10-21 | Sanofi Sa | Nouveaux derives de diarylcetones et leurs procedes de preparation et les compositions pharmaceutiques les contenant |
IL83230A (en) * | 1986-08-06 | 1992-06-21 | Tanabe Seiyaku Co | Phenoxyacetic acid derivatives,their preparation and pharmaceutical compositions containing them |
DE3629929A1 (de) * | 1986-09-03 | 1988-03-10 | Thomae Gmbh Dr K | Neue sulfonamido-aethylverbindungen, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
JPH01503233A (ja) * | 1986-10-28 | 1989-11-02 | スミス・クライン・アンド・フレンチ・ラボラトリース・リミテッド | 製薬活性化合物 |
GB8708233D0 (en) * | 1987-04-07 | 1987-05-13 | Smith Kline French Lab | Pharmaceutically active compounds |
KR880012221A (ko) * | 1987-04-13 | 1988-11-26 | 사노 가즈오 | 에스테르 또는 아미드를 활성성분으로 함유하는 약제 조성물 |
CA1294974C (fr) * | 1987-05-08 | 1992-01-28 | Sanji Hagishita | Derives de sulfonamide bicycliques et leur procede de preparation |
US4752616A (en) * | 1987-06-29 | 1988-06-21 | E. R. Squibb & Sons, Inc. | Arylthioalkylphenyl carboxylic acids, compositions containing same and method of use |
GB8717374D0 (en) * | 1987-07-22 | 1987-08-26 | Smith Kline French Lab | Pharmaceutically active compounds |
US4752613A (en) * | 1987-08-03 | 1988-06-21 | E. R. Squibb & Sons, Inc. | Sulphonamidothienylcarboxylic acid compounds |
US4783473A (en) * | 1987-09-02 | 1988-11-08 | E. R. Squibb & Sons, Inc. | Geminally substituted cyclic ether carboxylic acids, derivatives thereof, compositions containing same and method of use |
US4931460A (en) * | 1987-09-17 | 1990-06-05 | E. R. Squibb & Sons, Inc. | Post-ischemic myocardial dysfunction using thromboxane A2 antagonists |
JPH01175962A (ja) * | 1987-12-28 | 1989-07-12 | Tanabe Seiyaku Co Ltd | フェニル酢酸誘導体 |
EP0325245B1 (fr) * | 1988-01-19 | 1993-10-20 | Tanabe Seiyaku Co., Ltd. | Dérivés de l'acide phénoxyacétique, leur préparation, compositions pharmaceutiques les contenant et leurs utilisation |
US5066480A (en) * | 1988-04-11 | 1991-11-19 | E. R. Squibb & Sons, Inc. | Method of preventing or reducing adverse reactions to protamine using a thromboxane a2 receptor antagonist |
DE3819052A1 (de) * | 1988-06-04 | 1989-12-07 | Basf Ag | Neue sulfonamid-derivate, ihre herstellung und verwendung |
DE3829455A1 (de) * | 1988-08-31 | 1990-03-15 | Boehringer Mannheim Gmbh | Sulfonamidoalkyl-cyclohexan-verbindungen, verfahren zu ihrer herstellung sowie arzneimittel |
US4925873A (en) * | 1988-09-01 | 1990-05-15 | E. R. Squibb & Sons, Inc. | Method of treating skin injuries using thromboxane A2 receptor antagonists |
US5280043A (en) * | 1988-10-10 | 1994-01-18 | Smith Kline & French Laboratories Ltd. | Sulphonamido containing phenylalkanoic acids as thromboxane A2 antagonists |
GB8823731D0 (en) * | 1988-10-10 | 1988-11-16 | Smith Kline French Lab | Biologically active compounds |
US4959383A (en) * | 1988-10-31 | 1990-09-25 | E. R. Squibb & Sons, Inc. | Phenylsulfone alkenoic acids, derivatives thereof, compositions containing same and method of use |
US5006542A (en) * | 1988-10-31 | 1991-04-09 | E. R. Squibb & Sons, Inc. | Arylthioalkylphenyl carboxylic acids, derivatives thereof, compositions containing same and method of use |
US5070099A (en) * | 1988-10-31 | 1991-12-03 | E. R. Squibb & Sons, Inc. | Arylthioalkylphenyl carboxylic acids, derivatives thereof, compositions containing same method of use |
US5106991A (en) * | 1989-06-02 | 1992-04-21 | E. R. Squibb & Sons, Inc. | Geminally substituted thiaheterocyclic carboxylic acids and derivatives thereof |
US4975452A (en) * | 1989-06-02 | 1990-12-04 | E. R. Squibb & Sons, Inc. | Geminally substituted thiaheterocyclic carboxylic acids and derivatives thereof |
US5153214A (en) * | 1989-06-28 | 1992-10-06 | Ciba-Geigy Corporation | Certain (arylsulfonamido- and imidazolyl-)-substituted carboxylic acids and derivatives thereof and use for suppressing thromboxane activity |
US5025025A (en) * | 1989-06-28 | 1991-06-18 | Ciba-Geigy Corporation | (Arylsulfonamido- and pyridyl-)-substituted carboxylic acids and derivatives thereof and use for suppressing thromboxane activity |
DE4010536A1 (de) * | 1990-04-02 | 1991-10-10 | Boehringer Mannheim Gmbh | Pharmazeutische waessrige loesung von 4-(2-(benzolsulfonylamino)-ethyl)-phenoxyessigsaeure |
FR2665440B1 (fr) * | 1990-07-31 | 1994-02-04 | Lipha | Nouveaux cycloalkylsulfonamides substitues, procedes de preparation et medicaments les contenant. |
US5189211A (en) * | 1990-08-01 | 1993-02-23 | Taisho Pharmaceutical Co., Ltd. | Sulfonamide derivatives |
US5409959A (en) * | 1991-01-29 | 1995-04-25 | Genelabs Incorporated | Antithrombotic treatment with calix(n)arene compounds |
DE4109735A1 (de) * | 1991-03-25 | 1992-10-01 | Boehringer Mannheim Gmbh | Neue sulfonamide, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten |
US5280034A (en) * | 1991-08-23 | 1994-01-18 | E. R. Squibb & Sons, Inc. | Bis-heterocyclic prostaglandin analogs |
US5827868A (en) * | 1991-10-07 | 1998-10-27 | E. R. Squibb & Sons, Inc. | Prostaglandin analogs |
TW219358B (fr) * | 1991-12-20 | 1994-01-21 | Hokuriku Pharmaceutical | |
GB9220137D0 (en) * | 1992-09-23 | 1992-11-04 | Pfizer Ltd | Therapeutic agents |
JPH0753505A (ja) * | 1992-10-01 | 1995-02-28 | Hokuriku Seiyaku Co Ltd | ベンゼンスルホンアミド誘導体及びその用途 |
DK0896533T3 (da) * | 1996-02-22 | 2004-01-26 | Tularik Inc | Pentafluorbenzensulfonamider og analoger |
BR9710737A (pt) * | 1996-07-19 | 2000-01-11 | Tularik Inc | Pentafluorobenzenosulfonamidas e análogos. |
GB9702194D0 (en) * | 1997-02-04 | 1997-03-26 | Lilly Co Eli | Sulphonide derivatives |
FR2760235B1 (fr) * | 1997-02-28 | 1999-04-09 | Adir | Nouveaux derives de benzenesulfonylamine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
UA67754C2 (uk) * | 1997-10-10 | 2004-07-15 | Пфайзер, Інк. | Агоністи простагландину, фармацевтична композиція на їх основі (варіанти), спосіб нарощення та збереження кісткової маси у хребетних та спосіб лікування (варіанти) |
US6693137B1 (en) * | 1998-07-31 | 2004-02-17 | Eli Lilly And Company | Sulphonamide derivatives |
CZ20022048A3 (cs) | 1999-12-22 | 2004-03-17 | Pfizer Products Inc. | Selektivní agonisty receptoru EP4 při léčení osteoporosy |
US20050250854A1 (en) * | 2000-11-03 | 2005-11-10 | Amgen Inc. | Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents |
WO2002039958A2 (fr) | 2000-11-03 | 2002-05-23 | Tularik Inc. | Therapies combinees a base de pentafluorobenzenesulfonamides et d'agents antineoplasiques |
BRPI0517263A (pt) * | 2004-10-29 | 2008-10-07 | Astrazeneca Ab | novos derivados de sulfonamida como moduladores do receptor de glicocorticóide para o tratamento de doenças inflamatórias |
TW200829578A (en) | 2006-11-23 | 2008-07-16 | Astrazeneca Ab | Chemical compounds 537 |
JO2754B1 (en) | 2006-12-21 | 2014-03-15 | استرازينكا ايه بي | Amylendazoleil derivatives for the treatment of glucocorticoid-mediated disorders |
WO2008132154A1 (fr) * | 2007-04-27 | 2008-11-06 | Tibotec Pharmaceuticals Ltd. | Procédés pour la préparation de dérivés de n-isobutyl-n-(2-hydroxy-3-amino-4-phénylbutyl)-p-nitrobenzènesulfonylamide |
UY31831A (es) * | 2008-05-20 | 2010-01-05 | Astrazeneca Ab | Derivados de indazoles sustituidos con fenilo o piridinilo |
MX2011000051A (es) * | 2008-07-07 | 2011-07-28 | Fasgen Inc | Nuevos compuestos, composiciones farmaceuticas que contienen los mismos, metodos para usar los mismos, y metodos para preparar los mismos. |
US10207989B2 (en) | 2012-09-20 | 2019-02-19 | Temple University—Of the Commonwealth System of Higher Education | Substituted alkyl diaryl derivatives, methods of preparation and uses |
AU2015258805B2 (en) | 2014-05-16 | 2018-05-10 | Cumberland Pharmaceuticals, Inc. | Compositions and methods of treating cardiac fibrosis with ifetroban |
JP7033454B2 (ja) | 2015-06-30 | 2022-03-10 | カンバーランド ファーマシューティカルズ,インコーポレーテッド | Aerd/喘息におけるトロンボキサン受容体拮抗薬 |
WO2017023912A1 (fr) | 2015-08-03 | 2017-02-09 | Temple University - Of The Commonwealth System Of Higher Education | 2,4,6-trialcoxystyrylarylsulfones, sulfonamides et carboxamides, et procédés de préparation et d'utilisation |
CN109152767B (zh) | 2016-05-11 | 2022-10-21 | 坎伯兰医药品股份有限公司 | 用血栓烷-a2受体拮抗剂治疗肌营养不良的组合物和方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE542184A (fr) * | 1954-10-21 | |||
US3027405A (en) * | 1959-07-29 | 1962-03-27 | Geigy Chem Corp | Nu-(alkylarylsulfonyl)-amino acids and salts thereof |
US3991106A (en) * | 1974-09-13 | 1976-11-09 | Merck & Co., Inc. | 16-Ethers of 8-aza-9-dioxothia-11,12-seco-prostaglandins |
DK148576A (da) * | 1975-04-18 | 1976-10-19 | Boehringer Mannheim Gmbh | Fenylalkankarbonsyrederivater og fremgangsmade til deres fremstilling |
US4112236A (en) * | 1977-04-04 | 1978-09-05 | Merck & Co., Inc. | Interphenylene 8-aza-9-dioxothia-11,12-secoprostaglandins |
GB1572201A (en) * | 1977-04-05 | 1980-07-23 | Bristol Myers Co | Cephalosporins |
DE2809377A1 (de) * | 1978-03-04 | 1979-09-13 | Boehringer Mannheim Gmbh | Phenoxyalkylcarbonsaeure-derivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel |
DE3000519A1 (de) * | 1979-02-01 | 1980-08-14 | Byk Gulden Lomberg Chem Fab | Sulfonamido-alkansaeuren, ihre verwendung und herstellung sowie sie enthaltende arzneimittel |
-
1980
- 1980-01-07 DE DE19803000377 patent/DE3000377A1/de not_active Withdrawn
- 1980-12-17 CA CA000366994A patent/CA1241341A/fr not_active Expired
- 1980-12-24 DE DE8080108207T patent/DE3067068D1/de not_active Expired
- 1980-12-24 EP EP80108207A patent/EP0031954B1/fr not_active Expired
- 1980-12-24 AT AT80108207T patent/ATE6641T1/de not_active IP Right Cessation
- 1980-12-29 GR GR63765A patent/GR72486B/el unknown
- 1980-12-31 FI FI804085A patent/FI73667C/fi not_active IP Right Cessation
- 1980-12-31 CS CS809599A patent/CS238611B2/cs unknown
- 1980-12-31 IL IL61834A patent/IL61834A/xx not_active IP Right Cessation
-
1981
- 1981-01-02 ZA ZA00810032A patent/ZA8132B/xx unknown
- 1981-01-02 PT PT72305A patent/PT72305B/pt not_active IP Right Cessation
- 1981-01-03 ES ES498308A patent/ES498308A0/es active Granted
- 1981-01-04 SU SU813223600A patent/SU1088664A3/ru active
- 1981-01-05 IE IE6/81A patent/IE50657B1/en not_active IP Right Cessation
- 1981-01-05 PH PH25051A patent/PH18739A/en unknown
- 1981-01-05 AU AU65974/81A patent/AU538993B2/en not_active Ceased
- 1981-01-06 YU YU8/81A patent/YU42995B/xx unknown
- 1981-01-06 DD DD81226847A patent/DD157190A5/de unknown
- 1981-01-06 PL PL1981229072A patent/PL127050B1/pl unknown
- 1981-01-07 JP JP54081A patent/JPS56100757A/ja active Granted
-
1982
- 1982-07-07 US US06/395,882 patent/US4443477A/en not_active Expired - Lifetime
-
1987
- 1987-01-15 SG SG23/87A patent/SG2387G/en unknown
- 1987-09-24 HK HK688/87A patent/HK68887A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
CS238611B2 (en) | 1985-12-16 |
JPS6352625B2 (fr) | 1988-10-19 |
GR72486B (fr) | 1983-11-14 |
ES8200655A1 (es) | 1981-12-01 |
ATE6641T1 (de) | 1984-03-15 |
PL127050B1 (en) | 1983-09-30 |
IE810006L (en) | 1981-07-07 |
DE3000377A1 (de) | 1981-07-09 |
US4443477A (en) | 1984-04-17 |
IL61834A0 (en) | 1981-01-30 |
HK68887A (en) | 1987-10-02 |
FI73667B (fi) | 1987-07-31 |
FI804085L (fi) | 1981-07-08 |
PH18739A (en) | 1985-09-16 |
CA1241341A (fr) | 1988-08-30 |
PT72305B (de) | 1981-12-17 |
DE3067068D1 (en) | 1984-04-19 |
EP0031954B1 (fr) | 1984-03-14 |
IL61834A (en) | 1984-06-29 |
ES498308A0 (es) | 1981-12-01 |
AU538993B2 (en) | 1984-09-06 |
AU6597481A (en) | 1981-07-16 |
SG2387G (en) | 1987-11-13 |
PT72305A (de) | 1981-02-01 |
PL229072A1 (fr) | 1982-04-26 |
SU1088664A3 (ru) | 1984-04-23 |
YU881A (en) | 1983-10-31 |
ZA8132B (en) | 1982-02-24 |
IE50657B1 (en) | 1986-06-11 |
YU42995B (en) | 1989-02-28 |
JPS56100757A (en) | 1981-08-12 |
EP0031954A2 (fr) | 1981-07-15 |
FI73667C (fi) | 1987-11-09 |
EP0031954A3 (en) | 1981-11-11 |
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