FI804085L - Foerfarande foer framstaellning av nya sulfonamider - Google Patents

Foerfarande foer framstaellning av nya sulfonamider

Info

Publication number
FI804085L
FI804085L FI804085A FI804085A FI804085L FI 804085 L FI804085 L FI 804085L FI 804085 A FI804085 A FI 804085A FI 804085 A FI804085 A FI 804085A FI 804085 L FI804085 L FI 804085L
Authority
FI
Finland
Prior art keywords
lower alkyl
sulfonamiders
aryl
frequency refrigeration
aralkenyl
Prior art date
Application number
FI804085A
Other languages
English (en)
Other versions
FI73667C (fi
FI73667B (fi
Inventor
Ernst-Christian Witte
Hans Peter Wolff
Karlheinz Stegmeier
Egon Roesch
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of FI804085L publication Critical patent/FI804085L/fi
Application granted granted Critical
Publication of FI73667B publication Critical patent/FI73667B/fi
Publication of FI73667C publication Critical patent/FI73667C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Devices That Are Associated With Refrigeration Equipment (AREA)
FI804085A 1980-01-07 1980-12-31 Foerfarande foer framstaellning av nya sulfonamider. FI73667C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19803000377 DE3000377A1 (de) 1980-01-07 1980-01-07 Neue sulfonamide, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
DE3000377 1980-01-07

Publications (3)

Publication Number Publication Date
FI804085L true FI804085L (fi) 1981-07-08
FI73667B FI73667B (fi) 1987-07-31
FI73667C FI73667C (fi) 1987-11-09

Family

ID=6091629

Family Applications (1)

Application Number Title Priority Date Filing Date
FI804085A FI73667C (fi) 1980-01-07 1980-12-31 Foerfarande foer framstaellning av nya sulfonamider.

Country Status (22)

Country Link
US (1) US4443477A (fi)
EP (1) EP0031954B1 (fi)
JP (1) JPS56100757A (fi)
AT (1) ATE6641T1 (fi)
AU (1) AU538993B2 (fi)
CA (1) CA1241341A (fi)
CS (1) CS238611B2 (fi)
DD (1) DD157190A5 (fi)
DE (2) DE3000377A1 (fi)
ES (1) ES8200655A1 (fi)
FI (1) FI73667C (fi)
GR (1) GR72486B (fi)
HK (1) HK68887A (fi)
IE (1) IE50657B1 (fi)
IL (1) IL61834A (fi)
PH (1) PH18739A (fi)
PL (1) PL127050B1 (fi)
PT (1) PT72305B (fi)
SG (1) SG2387G (fi)
SU (1) SU1088664A3 (fi)
YU (1) YU42995B (fi)
ZA (1) ZA8132B (fi)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
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AU567140B2 (en) * 1984-01-06 1987-11-12 Shionogi & Co., Ltd. Sulphonamido-benzamide derivatives
EP0194548A3 (de) * 1985-03-12 1988-08-17 Dr. Karl Thomae GmbH Neue Sulfonylaminoäthylverbindungen, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
DE3535167A1 (de) * 1985-10-02 1987-04-09 Boehringer Mannheim Gmbh Neue sulfonyl-phenyl(alkyl)amine, verfahren zu ihrer herstellung sowie arzneimittel
US4689182A (en) * 1985-12-20 1987-08-25 Warner-Lambert Company Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity
FR2598412B1 (fr) * 1986-03-12 1988-10-21 Sanofi Sa Nouveaux derives de diarylcetones et leurs procedes de preparation et les compositions pharmaceutiques les contenant
IL83230A (en) * 1986-08-06 1992-06-21 Tanabe Seiyaku Co Phenoxyacetic acid derivatives,their preparation and pharmaceutical compositions containing them
DE3629929A1 (de) * 1986-09-03 1988-03-10 Thomae Gmbh Dr K Neue sulfonamido-aethylverbindungen, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
WO1988003137A1 (en) * 1986-10-28 1988-05-05 Smith Kline & French Laboratories Limited Tetrahydroisoquinolin-2-yl derivatives of carboxylic acids as thromboxane a2 antagonists
GB8708233D0 (en) * 1987-04-07 1987-05-13 Smith Kline French Lab Pharmaceutically active compounds
KR880012221A (ko) * 1987-04-13 1988-11-26 사노 가즈오 에스테르 또는 아미드를 활성성분으로 함유하는 약제 조성물
CA1294974C (en) * 1987-05-08 1992-01-28 Sanji Hagishita Bicyclic sulfonamide derivatives and process therefor
US4752616A (en) * 1987-06-29 1988-06-21 E. R. Squibb & Sons, Inc. Arylthioalkylphenyl carboxylic acids, compositions containing same and method of use
GB8717374D0 (en) * 1987-07-22 1987-08-26 Smith Kline French Lab Pharmaceutically active compounds
US4752613A (en) * 1987-08-03 1988-06-21 E. R. Squibb & Sons, Inc. Sulphonamidothienylcarboxylic acid compounds
US4783473A (en) * 1987-09-02 1988-11-08 E. R. Squibb & Sons, Inc. Geminally substituted cyclic ether carboxylic acids, derivatives thereof, compositions containing same and method of use
US4931460A (en) * 1987-09-17 1990-06-05 E. R. Squibb & Sons, Inc. Post-ischemic myocardial dysfunction using thromboxane A2 antagonists
JPH01175962A (ja) * 1987-12-28 1989-07-12 Tanabe Seiyaku Co Ltd フェニル酢酸誘導体
EP0325245B1 (en) * 1988-01-19 1993-10-20 Tanabe Seiyaku Co., Ltd. Phenoxyacetic acid derivatives, preparation thereof, pharmaceutical compositions comprising them and use
US5066480A (en) * 1988-04-11 1991-11-19 E. R. Squibb & Sons, Inc. Method of preventing or reducing adverse reactions to protamine using a thromboxane a2 receptor antagonist
DE3819052A1 (de) * 1988-06-04 1989-12-07 Basf Ag Neue sulfonamid-derivate, ihre herstellung und verwendung
DE3829455A1 (de) * 1988-08-31 1990-03-15 Boehringer Mannheim Gmbh Sulfonamidoalkyl-cyclohexan-verbindungen, verfahren zu ihrer herstellung sowie arzneimittel
US4925873A (en) * 1988-09-01 1990-05-15 E. R. Squibb & Sons, Inc. Method of treating skin injuries using thromboxane A2 receptor antagonists
GB8823731D0 (en) * 1988-10-10 1988-11-16 Smith Kline French Lab Biologically active compounds
US5280043A (en) * 1988-10-10 1994-01-18 Smith Kline & French Laboratories Ltd. Sulphonamido containing phenylalkanoic acids as thromboxane A2 antagonists
US4959383A (en) * 1988-10-31 1990-09-25 E. R. Squibb & Sons, Inc. Phenylsulfone alkenoic acids, derivatives thereof, compositions containing same and method of use
US5070099A (en) * 1988-10-31 1991-12-03 E. R. Squibb & Sons, Inc. Arylthioalkylphenyl carboxylic acids, derivatives thereof, compositions containing same method of use
US5006542A (en) * 1988-10-31 1991-04-09 E. R. Squibb & Sons, Inc. Arylthioalkylphenyl carboxylic acids, derivatives thereof, compositions containing same and method of use
US5106991A (en) * 1989-06-02 1992-04-21 E. R. Squibb & Sons, Inc. Geminally substituted thiaheterocyclic carboxylic acids and derivatives thereof
US4975452A (en) * 1989-06-02 1990-12-04 E. R. Squibb & Sons, Inc. Geminally substituted thiaheterocyclic carboxylic acids and derivatives thereof
US5153214A (en) * 1989-06-28 1992-10-06 Ciba-Geigy Corporation Certain (arylsulfonamido- and imidazolyl-)-substituted carboxylic acids and derivatives thereof and use for suppressing thromboxane activity
US5025025A (en) * 1989-06-28 1991-06-18 Ciba-Geigy Corporation (Arylsulfonamido- and pyridyl-)-substituted carboxylic acids and derivatives thereof and use for suppressing thromboxane activity
DE4010536A1 (de) * 1990-04-02 1991-10-10 Boehringer Mannheim Gmbh Pharmazeutische waessrige loesung von 4-(2-(benzolsulfonylamino)-ethyl)-phenoxyessigsaeure
FR2665440B1 (fr) * 1990-07-31 1994-02-04 Lipha Nouveaux cycloalkylsulfonamides substitues, procedes de preparation et medicaments les contenant.
US5189211A (en) * 1990-08-01 1993-02-23 Taisho Pharmaceutical Co., Ltd. Sulfonamide derivatives
US5409959A (en) * 1991-01-29 1995-04-25 Genelabs Incorporated Antithrombotic treatment with calix(n)arene compounds
DE4109735A1 (de) * 1991-03-25 1992-10-01 Boehringer Mannheim Gmbh Neue sulfonamide, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten
US5280034A (en) * 1991-08-23 1994-01-18 E. R. Squibb & Sons, Inc. Bis-heterocyclic prostaglandin analogs
US5827868A (en) * 1991-10-07 1998-10-27 E. R. Squibb & Sons, Inc. Prostaglandin analogs
TW219358B (fi) * 1991-12-20 1994-01-21 Hokuriku Pharmaceutical
GB9220137D0 (en) * 1992-09-23 1992-11-04 Pfizer Ltd Therapeutic agents
JPH0753505A (ja) * 1992-10-01 1995-02-28 Hokuriku Seiyaku Co Ltd ベンゼンスルホンアミド誘導体及びその用途
DK0896533T3 (da) * 1996-02-22 2004-01-26 Tularik Inc Pentafluorbenzensulfonamider og analoger
CN1147294C (zh) * 1996-07-19 2004-04-28 图拉列克股份有限公司 五氟苯磺酰胺及其类似物
GB9702194D0 (en) * 1997-02-04 1997-03-26 Lilly Co Eli Sulphonide derivatives
FR2760235B1 (fr) * 1997-02-28 1999-04-09 Adir Nouveaux derives de benzenesulfonylamine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
UA67754C2 (uk) * 1997-10-10 2004-07-15 Пфайзер, Інк. Агоністи простагландину, фармацевтична композиція на їх основі (варіанти), спосіб нарощення та збереження кісткової маси у хребетних та спосіб лікування (варіанти)
US6693137B1 (en) * 1998-07-31 2004-02-17 Eli Lilly And Company Sulphonamide derivatives
AP2002002555A0 (en) 1999-12-22 2002-06-30 Pfizer Prod Inc EP4 Receptor selective agonists in the treatment of osteoporosis.
US20050250854A1 (en) * 2000-11-03 2005-11-10 Amgen Inc. Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents
WO2002039958A2 (en) 2000-11-03 2002-05-23 Tularik Inc. Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents
KR20070068432A (ko) * 2004-10-29 2007-06-29 아스트라제네카 아베 염증 질환의 치료를 위한 글루코코르티코이드 수용체조절제로서의 신규 술폰아미드 유도체
TW200829578A (en) 2006-11-23 2008-07-16 Astrazeneca Ab Chemical compounds 537
JO2754B1 (en) 2006-12-21 2014-03-15 استرازينكا ايه بي Amylendazoleil derivatives for the treatment of glucocorticoid-mediated disorders
PT2152667E (pt) * 2007-04-27 2011-04-06 Tibotec Pharm Ltd Processos para a preparação de derivados de n-isobutil-n- (2-hidroxi-3-amino-4-fenilbutil)-p-nitrobenzenosulfonilamida
SA109300309B1 (ar) 2008-05-20 2013-01-22 باير شيرنج فارما ايه جي مشتقات فينيل وبنزو داي أوكسينيل إندازول بها استبدال
CN102395270B (zh) * 2008-07-07 2014-11-12 法斯根公司 化合物、含有其的药物组合物、其使用方法及其制备方法
ES2863538T3 (es) 2012-09-20 2021-10-11 Univ Temple Derivados de alquil diarilo sustituidos, métodos de preparación y usos
US9693998B2 (en) 2014-05-16 2017-07-04 Cumberland Pharmaceuticals, Inc. Compositions and methods of treating cardiac fibrosis with ifetroban
CA2990880A1 (en) 2015-06-30 2017-01-05 Cumberland Pharmaceuticals, Inc. Thromboxane receptor antagonists in aerd/asthma
WO2017023912A1 (en) 2015-08-03 2017-02-09 Temple University - Of The Commonwealth System Of Higher Education 2,4,6-trialkoxystryl aryl sulfones, sulfonamides and carboxamides, and methods of preparation and use
US10064845B2 (en) 2016-05-11 2018-09-04 Cumberland Pharmaceuticals, Inc. Compositions and methods of treating muscular dystrophy with thromboxane-A2 receptor antagonists

Family Cites Families (8)

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BE542184A (fi) * 1954-10-21
US3027405A (en) * 1959-07-29 1962-03-27 Geigy Chem Corp Nu-(alkylarylsulfonyl)-amino acids and salts thereof
US3991106A (en) * 1974-09-13 1976-11-09 Merck & Co., Inc. 16-Ethers of 8-aza-9-dioxothia-11,12-seco-prostaglandins
DK148576A (da) * 1975-04-18 1976-10-19 Boehringer Mannheim Gmbh Fenylalkankarbonsyrederivater og fremgangsmade til deres fremstilling
US4112236A (en) * 1977-04-04 1978-09-05 Merck & Co., Inc. Interphenylene 8-aza-9-dioxothia-11,12-secoprostaglandins
GB1572201A (en) * 1977-04-05 1980-07-23 Bristol Myers Co Cephalosporins
DE2809377A1 (de) * 1978-03-04 1979-09-13 Boehringer Mannheim Gmbh Phenoxyalkylcarbonsaeure-derivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
DE3000519A1 (de) * 1979-02-01 1980-08-14 Byk Gulden Lomberg Chem Fab Sulfonamido-alkansaeuren, ihre verwendung und herstellung sowie sie enthaltende arzneimittel

Also Published As

Publication number Publication date
DE3067068D1 (en) 1984-04-19
FI73667C (fi) 1987-11-09
PH18739A (en) 1985-09-16
SG2387G (en) 1987-11-13
SU1088664A3 (ru) 1984-04-23
EP0031954A2 (de) 1981-07-15
ATE6641T1 (de) 1984-03-15
ES498308A0 (es) 1981-12-01
JPS56100757A (en) 1981-08-12
EP0031954B1 (de) 1984-03-14
PT72305B (de) 1981-12-17
JPS6352625B2 (fi) 1988-10-19
CA1241341A (en) 1988-08-30
US4443477A (en) 1984-04-17
EP0031954A3 (en) 1981-11-11
DD157190A5 (de) 1982-10-20
FI73667B (fi) 1987-07-31
AU6597481A (en) 1981-07-16
IL61834A0 (en) 1981-01-30
IE810006L (en) 1981-07-07
PL229072A1 (fi) 1982-04-26
ZA8132B (en) 1982-02-24
YU881A (en) 1983-10-31
PL127050B1 (en) 1983-09-30
IL61834A (en) 1984-06-29
AU538993B2 (en) 1984-09-06
GR72486B (fi) 1983-11-14
YU42995B (en) 1989-02-28
PT72305A (de) 1981-02-01
CS238611B2 (en) 1985-12-16
ES8200655A1 (es) 1981-12-01
IE50657B1 (en) 1986-06-11
DE3000377A1 (de) 1981-07-09
HK68887A (en) 1987-10-02

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Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: BOEHRINGER MANNHEIM GMBH