DD150605A5 - Verfahren zur herstellung dihalogen-substituierter kondensierter pyrimidin-4-on-derivate - Google Patents

Verfahren zur herstellung dihalogen-substituierter kondensierter pyrimidin-4-on-derivate Download PDF

Info

Publication number
DD150605A5
DD150605A5 DD80221053A DD22105380A DD150605A5 DD 150605 A5 DD150605 A5 DD 150605A5 DD 80221053 A DD80221053 A DD 80221053A DD 22105380 A DD22105380 A DD 22105380A DD 150605 A5 DD150605 A5 DD 150605A5
Authority
DD
German Democratic Republic
Prior art keywords
general formula
compounds
item
meaning
pyrido
Prior art date
Application number
DD80221053A
Other languages
German (de)
English (en)
Inventor
Istvan Hermecz
Tibor Breining
Lelle Vasvari
Agnes Horvath
Zoltan Meszaros
Istvan Bitter
Jozsef Koekoesi
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of DD150605A5 publication Critical patent/DD150605A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B62/00—Reactive dyes, i.e. dyes which form covalent bonds with the substrates or which polymerise with themselves

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
DD80221053A 1979-05-11 1980-05-12 Verfahren zur herstellung dihalogen-substituierter kondensierter pyrimidin-4-on-derivate DD150605A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU79CI1932A HU179443B (en) 1979-05-11 1979-05-11 Process for producing substituted geminal dihalogeno-derivatives of pyrido-square bracket-1,2-a-square closed-pyrimidines,pyrrolo-square bracket-1,2-a-square bracket closed-pyrimidines and pyrimido-square bracket-1,2,-a-square bracket closed-asepines

Publications (1)

Publication Number Publication Date
DD150605A5 true DD150605A5 (de) 1981-09-09

Family

ID=10994747

Family Applications (1)

Application Number Title Priority Date Filing Date
DD80221053A DD150605A5 (de) 1979-05-11 1980-05-12 Verfahren zur herstellung dihalogen-substituierter kondensierter pyrimidin-4-on-derivate

Country Status (24)

Country Link
JP (1) JPS5615286A (it)
AT (1) AT377261B (it)
BE (1) BE883217A (it)
CA (1) CA1141379A (it)
CH (1) CH646971A5 (it)
CS (1) CS241025B2 (it)
DD (1) DD150605A5 (it)
DE (1) DE3017564A1 (it)
DK (1) DK204680A (it)
ES (1) ES491896A0 (it)
FI (1) FI68825C (it)
FR (1) FR2456101A1 (it)
GB (1) GB2051048B (it)
GR (1) GR68518B (it)
HU (1) HU179443B (it)
IL (1) IL59967A (it)
IT (1) IT1133085B (it)
LU (1) LU82437A1 (it)
NL (1) NL8002678A (it)
NO (1) NO152607C (it)
PL (1) PL124035B1 (it)
PT (1) PT71213A (it)
SE (1) SE441747B (it)
SU (1) SU1151210A3 (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU178453B (en) * 1979-05-11 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 9-hydrazino-4-oxo-6,7,8,9-tetrahydro-4h-p-pyrido-square bracket-1,2-a-square bracket closed-pyrimidine derivatives
US4395549A (en) 1981-10-02 1983-07-26 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. 6-Hydrazono-pyrido[2,1-b] quinazoline-11 ones
IL69274A (en) * 1982-08-05 1986-08-31 Erba Farmitalia (substituted amino)derivatives of 3-benzylidene-pyrrolo(2,1-b)quinazolin-9-ones and 6-benzylidene-pyrido(2,1-b)quinazolin-11-ones,their preparation and pharmaceutical compositions containing them
US5158952A (en) * 1988-11-07 1992-10-27 Janssen Pharmaceutica N.V. 3-[2-[4-(6-fluoro-1,2-benzisoxozol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9 tetrahydro-9-hydroxy-2-methyl-4H-pyrido [1,2-a]pyrimidin-4-one, compositions and method of use
UA72189C2 (uk) 1997-11-17 2005-02-15 Янссен Фармацевтика Н.В. Фармацевтична композиція, що містить водну суспензію субмікронних ефірів 9-гідроксирисперидон жирних кислот

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH538494A (de) * 1966-11-02 1973-06-30 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung neuer Homopyrimidazol-Derivate
HU178496B (en) * 1977-12-29 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 6,7,8,9-tetrahydro-4h-pyrido/1,2-a/pyrimidine derivatives with antiallergic activity

Also Published As

Publication number Publication date
IL59967A (en) 1984-05-31
SU1151210A3 (ru) 1985-04-15
NO801378L (no) 1980-11-12
SE8003479L (sv) 1980-11-12
ES8102570A1 (es) 1981-02-16
PT71213A (en) 1980-06-01
BE883217A (fr) 1980-09-01
CS241025B2 (en) 1986-03-13
CS325880A2 (en) 1985-06-13
AT377261B (de) 1985-02-25
PL224163A1 (it) 1981-02-13
IL59967A0 (en) 1980-07-31
HU179443B (en) 1982-10-28
FI68825B (fi) 1985-07-31
NL8002678A (nl) 1980-11-13
LU82437A1 (fr) 1980-07-31
GR68518B (it) 1982-01-11
GB2051048A (en) 1981-01-14
GB2051048B (en) 1983-01-19
FR2456101A1 (fr) 1980-12-05
FI801512A (fi) 1980-11-12
IT1133085B (it) 1986-07-09
DK204680A (da) 1980-11-12
JPS5615286A (en) 1981-02-14
FI68825C (fi) 1985-11-11
CH646971A5 (de) 1984-12-28
SE441747B (sv) 1985-11-04
NO152607B (no) 1985-07-15
ES491896A0 (es) 1981-02-16
IT8067719A0 (it) 1980-05-09
DE3017564A1 (de) 1980-11-13
PL124035B1 (en) 1982-12-31
NO152607C (no) 1985-10-23
CA1141379A (en) 1983-02-15
ATA247580A (de) 1984-07-15
FR2456101B1 (it) 1985-04-05

Similar Documents

Publication Publication Date Title
DE2614406A1 (de) Tetracyclische verbindungen, verfahren zu deren herstellung und arzneimittel, enthaltend diese verbindungen
DE2818676A1 (de) Substituierte 5,6-dimethylpyrrolo 2,3-d pyrimidine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DD202152A5 (de) Verfahren zur herstellung von phenylpiperazinderivaten
DE3442035A1 (de) 6-vinyl-furo-(3,4-c)-pyridin-derivate, verfahren zu deren herstellung, und diese enthaltende pharmazeutische zusammensetzung
DE1695929C3 (de) 1 ^-Dihydro-1 -hydroxy^-imino^-amino-6-methylpyrimidine sowie ein Verfahren zu deren Herstellung
DE2726389A1 (de) Pyrazolo eckige klammer auf 1,5-c eckige klammer zu chinazoline, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
DD150605A5 (de) Verfahren zur herstellung dihalogen-substituierter kondensierter pyrimidin-4-on-derivate
DE3780015T2 (de) Kondensierte heterocyclische tetrahydroaminochinolinole und verwandte verbindungen, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
EP0225522A1 (de) Imidazopyridazinalkensäureamide, Verfahren ihrer Herstellung, Zwischenprodukte zu ihrer Herstellung
DE2928219A1 (de) Optisch aktive oder racemische 10-brom-14-oxo-e-homoeburnanderivate, 1-alkyl-9-bromhexahydroindolochinoliziniumderivate, 1-alkyl-1-(2'-alkoxycarbonylaethyl)-9-brom-1,2,3,4,6,7,12,12b-octahydroindolo eckige klammer auf 2,3-a eckige klammer zu chinolizin- bzw. 1-alkyl-1 -(2'-carboxyaethyl)-9-brom-1,2,3,4,6,7, 12,12b-octahydroindolo eckige klammer auf 2,3-a eckige klammer zu chinolizinderivate und 5-bromtryptamin-2-carbonsaeurederivate, verfahren zur herstellung derselben und von optisch aktiven oder racemischen 10-bromvincaminsaeureesterderivaten und optisch aktive oder racemische 10-bromvincaminsaeureesterderivate sowie erstere oder letztere enthaltende arzneimittel
DE3109769A1 (de) Die erfindung betrifft ein neues verfahren zur herstellung von 5,11-dihydro-6h-pyrido (2,3-b) (1,4) benzodiazepin-6-on-derivaten
CH653032A5 (de) Bicyclische verbindungen, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel.
DE3875031T2 (de) Substituierte dibenzocycloheptenimine.
DE2346466A1 (de) Neue pyrazolopyridobenzodiazepinone mit ihren salzen
DD283392A5 (de) Verfahren zur herstellung von neuen 4-oxo-4h-pyrido[1,2-a]pyrimidin-3-carbonsaeureamid-derivaten und deren verwendung
DE10304141B4 (de) Verfahren zur Herstellung von Chinazolin-Alkaloiden
DD150604A5 (de) Verfahren zur herstellung von 9-amino-6,7-dihydro-4h-pyrido(1,2-a)pyrimidin-4-on-derivaten
DD208805A5 (de) Verfahren zur herstellung von alkoxyvincaminsaeureestern und alkoxyapovincaminsaeureestern
CH641179A5 (de) Heterocyclische verbindungen mit stickstoff im ringsystem und verfahren zur herstellung derselben.
DE2257376A1 (de) Organische verbindungen und verfahren zu ihrer herstellung
DE2813734A1 (de) Pyrazolo eckige klammer auf 1,5-a eckige klammer zu pyrido eckige klammer auf 2,3-d eckige klammer zu pyrimidin-9 (4h)-on-derivate
DE2629877A1 (de) Pyrrolo eckige klammer auf 2,1-b eckige klammer zu eckige klammer auf 3 eckige klammer zu benzazepine
DE2315422A1 (de) Neue pyrido(1,2-a)pyrimidin- und neue pyrido(1,2-a)-(1,3)-diazepin-derivate und verfahren zur herstellung derselben
CH655115A5 (de) Substituierte aethenylderivate von 1h-pyrazolo-(1,5-a)-pyrimidin und verfahren zur herstellung derselben.
DE2222186C3 (de) Verfahren zur Herstellung von Vincamin und analogen Verbindungen