CS241025B2 - Method of fussed pyrimidine-4-ons' dihalogenated derivatives production - Google Patents

Method of fussed pyrimidine-4-ons' dihalogenated derivatives production Download PDF

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Publication number
CS241025B2
CS241025B2 CS803258A CS325880A CS241025B2 CS 241025 B2 CS241025 B2 CS 241025B2 CS 803258 A CS803258 A CS 803258A CS 325880 A CS325880 A CS 325880A CS 241025 B2 CS241025 B2 CS 241025B2
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CS
Czechoslovakia
Prior art keywords
formula
compound
hydrogen
compounds
group
Prior art date
Application number
CS803258A
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Czech (cs)
English (en)
Other versions
CS325880A2 (en
Inventor
Istvan Hermecz
Tibor Breining
Lelle Vasvari
Agnes Horvath
Zoltan Meszaros
Istvan Bitter
Jozsef Koekoese
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of CS325880A2 publication Critical patent/CS325880A2/cs
Publication of CS241025B2 publication Critical patent/CS241025B2/cs

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B62/00Reactive dyes, i.e. dyes which form covalent bonds with the substrates or which polymerise with themselves

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
CS803258A 1979-05-11 1980-05-08 Method of fussed pyrimidine-4-ons' dihalogenated derivatives production CS241025B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU79CI1932A HU179443B (en) 1979-05-11 1979-05-11 Process for producing substituted geminal dihalogeno-derivatives of pyrido-square bracket-1,2-a-square closed-pyrimidines,pyrrolo-square bracket-1,2-a-square bracket closed-pyrimidines and pyrimido-square bracket-1,2,-a-square bracket closed-asepines

Publications (2)

Publication Number Publication Date
CS325880A2 CS325880A2 (en) 1985-06-13
CS241025B2 true CS241025B2 (en) 1986-03-13

Family

ID=10994747

Family Applications (1)

Application Number Title Priority Date Filing Date
CS803258A CS241025B2 (en) 1979-05-11 1980-05-08 Method of fussed pyrimidine-4-ons' dihalogenated derivatives production

Country Status (24)

Country Link
JP (1) JPS5615286A (it)
AT (1) AT377261B (it)
BE (1) BE883217A (it)
CA (1) CA1141379A (it)
CH (1) CH646971A5 (it)
CS (1) CS241025B2 (it)
DD (1) DD150605A5 (it)
DE (1) DE3017564A1 (it)
DK (1) DK204680A (it)
ES (1) ES491896A0 (it)
FI (1) FI68825C (it)
FR (1) FR2456101A1 (it)
GB (1) GB2051048B (it)
GR (1) GR68518B (it)
HU (1) HU179443B (it)
IL (1) IL59967A (it)
IT (1) IT1133085B (it)
LU (1) LU82437A1 (it)
NL (1) NL8002678A (it)
NO (1) NO152607C (it)
PL (1) PL124035B1 (it)
PT (1) PT71213A (it)
SE (1) SE441747B (it)
SU (1) SU1151210A3 (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU178453B (en) * 1979-05-11 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 9-hydrazino-4-oxo-6,7,8,9-tetrahydro-4h-p-pyrido-square bracket-1,2-a-square bracket closed-pyrimidine derivatives
US4395549A (en) 1981-10-02 1983-07-26 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. 6-Hydrazono-pyrido[2,1-b] quinazoline-11 ones
IL69274A (en) * 1982-08-05 1986-08-31 Erba Farmitalia (substituted amino)derivatives of 3-benzylidene-pyrrolo(2,1-b)quinazolin-9-ones and 6-benzylidene-pyrido(2,1-b)quinazolin-11-ones,their preparation and pharmaceutical compositions containing them
US5158952A (en) * 1988-11-07 1992-10-27 Janssen Pharmaceutica N.V. 3-[2-[4-(6-fluoro-1,2-benzisoxozol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9 tetrahydro-9-hydroxy-2-methyl-4H-pyrido [1,2-a]pyrimidin-4-one, compositions and method of use
UA72189C2 (uk) 1997-11-17 2005-02-15 Янссен Фармацевтика Н.В. Фармацевтична композиція, що містить водну суспензію субмікронних ефірів 9-гідроксирисперидон жирних кислот

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH538494A (de) * 1966-11-02 1973-06-30 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung neuer Homopyrimidazol-Derivate
HU178496B (en) * 1977-12-29 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 6,7,8,9-tetrahydro-4h-pyrido/1,2-a/pyrimidine derivatives with antiallergic activity

Also Published As

Publication number Publication date
IL59967A (en) 1984-05-31
SU1151210A3 (ru) 1985-04-15
NO801378L (no) 1980-11-12
SE8003479L (sv) 1980-11-12
ES8102570A1 (es) 1981-02-16
PT71213A (en) 1980-06-01
BE883217A (fr) 1980-09-01
DD150605A5 (de) 1981-09-09
CS325880A2 (en) 1985-06-13
AT377261B (de) 1985-02-25
PL224163A1 (it) 1981-02-13
IL59967A0 (en) 1980-07-31
HU179443B (en) 1982-10-28
FI68825B (fi) 1985-07-31
NL8002678A (nl) 1980-11-13
LU82437A1 (fr) 1980-07-31
GR68518B (it) 1982-01-11
GB2051048A (en) 1981-01-14
GB2051048B (en) 1983-01-19
FR2456101A1 (fr) 1980-12-05
FI801512A (fi) 1980-11-12
IT1133085B (it) 1986-07-09
DK204680A (da) 1980-11-12
JPS5615286A (en) 1981-02-14
FI68825C (fi) 1985-11-11
CH646971A5 (de) 1984-12-28
SE441747B (sv) 1985-11-04
NO152607B (no) 1985-07-15
ES491896A0 (es) 1981-02-16
IT8067719A0 (it) 1980-05-09
DE3017564A1 (de) 1980-11-13
PL124035B1 (en) 1982-12-31
NO152607C (no) 1985-10-23
CA1141379A (en) 1983-02-15
ATA247580A (de) 1984-07-15
FR2456101B1 (it) 1985-04-05

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