AT377261B - Verfahren zur herstellung von neuen kondensierten pyrimidin-4-on-derivaten und von deren salzen und optischen antipoden - Google Patents

Verfahren zur herstellung von neuen kondensierten pyrimidin-4-on-derivaten und von deren salzen und optischen antipoden

Info

Publication number
AT377261B
AT377261B AT0247580A AT247580A AT377261B AT 377261 B AT377261 B AT 377261B AT 0247580 A AT0247580 A AT 0247580A AT 247580 A AT247580 A AT 247580A AT 377261 B AT377261 B AT 377261B
Authority
AT
Austria
Prior art keywords
derivatives
salts
producing new
optical antipodes
new condensed
Prior art date
Application number
AT0247580A
Other languages
English (en)
Other versions
ATA247580A (de
Inventor
Istvan Dipl Ing Chem D Hermecz
Tibor Dipl Ing Chem Breining
Lelle Dr Vasvari
Agnes Dipl Ing Chem Dr Horvath
Zoltan Dipl Ing Chem Meszaros
Istvan Dipl Ing Chem Dr Bitter
Jozsef Dr Koekoesi
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of ATA247580A publication Critical patent/ATA247580A/de
Application granted granted Critical
Publication of AT377261B publication Critical patent/AT377261B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B62/00Reactive dyes, i.e. dyes which form covalent bonds with the substrates or which polymerise with themselves

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
AT0247580A 1979-05-11 1980-05-09 Verfahren zur herstellung von neuen kondensierten pyrimidin-4-on-derivaten und von deren salzen und optischen antipoden AT377261B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU79CI1932A HU179443B (en) 1979-05-11 1979-05-11 Process for producing substituted geminal dihalogeno-derivatives of pyrido-square bracket-1,2-a-square closed-pyrimidines,pyrrolo-square bracket-1,2-a-square bracket closed-pyrimidines and pyrimido-square bracket-1,2,-a-square bracket closed-asepines

Publications (2)

Publication Number Publication Date
ATA247580A ATA247580A (de) 1984-07-15
AT377261B true AT377261B (de) 1985-02-25

Family

ID=10994747

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0247580A AT377261B (de) 1979-05-11 1980-05-09 Verfahren zur herstellung von neuen kondensierten pyrimidin-4-on-derivaten und von deren salzen und optischen antipoden

Country Status (24)

Country Link
JP (1) JPS5615286A (de)
AT (1) AT377261B (de)
BE (1) BE883217A (de)
CA (1) CA1141379A (de)
CH (1) CH646971A5 (de)
CS (1) CS241025B2 (de)
DD (1) DD150605A5 (de)
DE (1) DE3017564A1 (de)
DK (1) DK204680A (de)
ES (1) ES491896A0 (de)
FI (1) FI68825C (de)
FR (1) FR2456101A1 (de)
GB (1) GB2051048B (de)
GR (1) GR68518B (de)
HU (1) HU179443B (de)
IL (1) IL59967A (de)
IT (1) IT1133085B (de)
LU (1) LU82437A1 (de)
NL (1) NL8002678A (de)
NO (1) NO152607C (de)
PL (1) PL124035B1 (de)
PT (1) PT71213A (de)
SE (1) SE441747B (de)
SU (1) SU1151210A3 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU178453B (en) * 1979-05-11 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 9-hydrazino-4-oxo-6,7,8,9-tetrahydro-4h-p-pyrido-square bracket-1,2-a-square bracket closed-pyrimidine derivatives
US4395549A (en) 1981-10-02 1983-07-26 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. 6-Hydrazono-pyrido[2,1-b] quinazoline-11 ones
IL69274A (en) * 1982-08-05 1986-08-31 Erba Farmitalia (substituted amino)derivatives of 3-benzylidene-pyrrolo(2,1-b)quinazolin-9-ones and 6-benzylidene-pyrido(2,1-b)quinazolin-11-ones,their preparation and pharmaceutical compositions containing them
US5158952A (en) * 1988-11-07 1992-10-27 Janssen Pharmaceutica N.V. 3-[2-[4-(6-fluoro-1,2-benzisoxozol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9 tetrahydro-9-hydroxy-2-methyl-4H-pyrido [1,2-a]pyrimidin-4-one, compositions and method of use
UA72189C2 (uk) 1997-11-17 2005-02-15 Янссен Фармацевтика Н.В. Фармацевтична композиція, що містить водну суспензію субмікронних ефірів 9-гідроксирисперидон жирних кислот

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT302311B (de) * 1966-11-02 1972-09-15 Chinoin Gyogyszer Es Vegyeszet Verfahren zur herstellung von homopyrimidazol-derivaten und deren saeureadditionssalzen und quaternaeren ammoniumsalzen
HU178496B (en) * 1977-12-29 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 6,7,8,9-tetrahydro-4h-pyrido/1,2-a/pyrimidine derivatives with antiallergic activity

Also Published As

Publication number Publication date
JPS5615286A (en) 1981-02-14
DE3017564A1 (de) 1980-11-13
IL59967A (en) 1984-05-31
PT71213A (en) 1980-06-01
GB2051048A (en) 1981-01-14
BE883217A (fr) 1980-09-01
DD150605A5 (de) 1981-09-09
NO801378L (no) 1980-11-12
FI801512A (fi) 1980-11-12
FI68825C (fi) 1985-11-11
CS325880A2 (en) 1985-06-13
PL124035B1 (en) 1982-12-31
CA1141379A (en) 1983-02-15
NO152607C (no) 1985-10-23
SE441747B (sv) 1985-11-04
CH646971A5 (de) 1984-12-28
DK204680A (da) 1980-11-12
PL224163A1 (de) 1981-02-13
LU82437A1 (fr) 1980-07-31
SU1151210A3 (ru) 1985-04-15
FR2456101A1 (fr) 1980-12-05
CS241025B2 (en) 1986-03-13
FI68825B (fi) 1985-07-31
HU179443B (en) 1982-10-28
IL59967A0 (en) 1980-07-31
NL8002678A (nl) 1980-11-13
GR68518B (de) 1982-01-11
ES8102570A1 (es) 1981-02-16
ES491896A0 (es) 1981-02-16
IT1133085B (it) 1986-07-09
GB2051048B (en) 1983-01-19
NO152607B (no) 1985-07-15
SE8003479L (sv) 1980-11-12
IT8067719A0 (it) 1980-05-09
ATA247580A (de) 1984-07-15
FR2456101B1 (de) 1985-04-05

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Legal Events

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ELJ Ceased due to non-payment of the annual fee