CZ299290B6 - Zpusob výroby beta-laktamové slouceniny, zpusob prípravy a/nebo zlepšení vláknitého mikrobiálního kmene a použití chemicky definovaného fermentacníhomédia - Google Patents

Zpusob výroby beta-laktamové slouceniny, zpusob prípravy a/nebo zlepšení vláknitého mikrobiálního kmene a použití chemicky definovaného fermentacníhomédia Download PDF

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CZ299290B6
CZ299290B6 CZ0295499A CZ295499A CZ299290B6 CZ 299290 B6 CZ299290 B6 CZ 299290B6 CZ 0295499 A CZ0295499 A CZ 0295499A CZ 295499 A CZ295499 A CZ 295499A CZ 299290 B6 CZ299290 B6 CZ 299290B6
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chemically defined
fermentation
medium
strain
lactam compound
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CZ0295499A
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CZ295499A3 (cs
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Laat@Wilhelmus Theodorus Antonius Maria De
Cornelis Gerardus Preusting@Johannes
Pieter Koekman@Bertus
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Dsm Ip Assets B.V.
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Publication of CZ295499A3 publication Critical patent/CZ295499A3/cs
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    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
    • C12N9/2408Glucanases acting on alpha -1,4-glucosidic bonds
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    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
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    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
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    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
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    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
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    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • C12P7/6445Glycerides
    • C12P7/6472Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor

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  • Biomedical Technology (AREA)
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  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
CZ0295499A 1997-02-20 1998-02-20 Zpusob výroby beta-laktamové slouceniny, zpusob prípravy a/nebo zlepšení vláknitého mikrobiálního kmene a použití chemicky definovaného fermentacníhomédia CZ299290B6 (cs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97200494 1997-02-20

Publications (2)

Publication Number Publication Date
CZ295499A3 CZ295499A3 (cs) 2000-04-12
CZ299290B6 true CZ299290B6 (cs) 2008-06-11

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CZ0295499A CZ299290B6 (cs) 1997-02-20 1998-02-20 Zpusob výroby beta-laktamové slouceniny, zpusob prípravy a/nebo zlepšení vláknitého mikrobiálního kmene a použití chemicky definovaného fermentacníhomédia

Country Status (17)

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US (3) US20020039758A1 (enExample)
EP (4) EP0970236B1 (enExample)
JP (4) JP4217277B2 (enExample)
KR (1) KR100576576B1 (enExample)
CN (2) CN100351386C (enExample)
AT (1) ATE327340T1 (enExample)
AU (1) AU6400098A (enExample)
BR (1) BR9807362A (enExample)
CZ (1) CZ299290B6 (enExample)
DE (1) DE69834630T2 (enExample)
ES (1) ES2262228T3 (enExample)
ID (1) ID23995A (enExample)
PL (1) PL335227A1 (enExample)
PT (1) PT970236E (enExample)
RU (1) RU99120113A (enExample)
SI (1) SI0970236T1 (enExample)
WO (1) WO1998037179A2 (enExample)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5340742A (en) 1988-09-07 1994-08-23 Omegatech Inc. Process for growing thraustochytrium and schizochytrium using non-chloride salts to produce a microfloral biomass having omega-3-highly unsaturated fatty acids
KR100576576B1 (ko) * 1997-02-20 2006-05-04 디에스엠 아이피 어셋츠 비.브이. 화학적 합성 배지를 이용하는 가치있는 화합물들의 산업적 규모의 발효적 생산
US6004784A (en) * 1998-09-14 1999-12-21 General Electric Co. Fermentation medium and method for producing α, ω -alkanedicarboxylic acids
US6440708B1 (en) * 1998-09-29 2002-08-27 Dsm N.V. Fermentation of clavulanic acid at a controlled level of ammonia
CN101519679B (zh) 2000-01-28 2013-11-13 Dsmip资产公司 通过在发酵罐中高密度培养真核微生物来增加含有多烯脂肪酸的脂质的产生
DE10106493B4 (de) * 2001-02-13 2010-11-04 Plasmidfactory Gmbh & Co. Kg Verfahren zur Herstellung von Nukleinsäuren
CN100529066C (zh) 2002-07-01 2009-08-19 诺维信公司 在发酵过程中加入单丙二醇
KR100454508B1 (ko) * 2002-07-05 2004-11-03 허명준 소취기능과 다제내성균에 대한 멸균력을 갖는 자연기능수및 그의 제조방법
US6955892B2 (en) * 2002-11-12 2005-10-18 Akzo Nobel N.V. Feeding processes for fermentation
DE10317877A1 (de) * 2003-04-17 2004-11-18 Consortium für elektrochemische Industrie GmbH Verfahren zur Herstellung von Sporidiobolus ruineniae Stämmen mit verbesserter Coenzym Q10-Produktion
WO2004106347A1 (en) 2003-05-28 2004-12-09 Dsm Ip Assets B.V. Cephem compound
WO2005078115A1 (en) 2004-02-04 2005-08-25 Merck & Co., Inc. Process for large scale production of plasmid dna by e. coli fermentation
US20080050779A1 (en) * 2004-06-16 2008-02-28 Aurelia Defachelles Fermentation Process Using Faba Beans as Nitrogen Source
CN103589650A (zh) 2005-03-18 2014-02-19 米克罗比亚公司 产油酵母和真菌中类胡萝卜素的产生
KR101283288B1 (ko) * 2005-03-24 2013-07-11 디에스엠 아이피 어셋츠 비.브이. 유용한 화합물의 미생물적 제조 방법
US7990102B2 (en) * 2006-02-09 2011-08-02 Karl Frederick Scheucher Cordless power supply
KR100839874B1 (ko) * 2006-07-07 2008-06-19 자연과생명기술(주) 분말 발효제 제조 방법
US8691555B2 (en) 2006-09-28 2014-04-08 Dsm Ip Assests B.V. Production of carotenoids in oleaginous yeast and fungi
US20100120154A1 (en) 2007-03-21 2010-05-13 Dsm Ip Assets B.V. Method for homologous recombination
BRPI0816290A2 (pt) * 2007-09-05 2014-10-14 Microbia Inc Isolamento de micro-organismos formadores de péletes
EP2310487A2 (en) 2008-08-05 2011-04-20 DSM IP Assets B.V. Adipoyl-7-adca producing strains
EP2213723A1 (en) 2009-01-30 2010-08-04 Novozymes A/S Isomaltose for fungus fermentation
EP2401371A1 (en) 2009-02-27 2012-01-04 Novozymes A/S Mutant cells having reduced expression of metallopeptidase, suitable for recombinant polypeptide production
BR112012000078A2 (pt) 2009-07-03 2017-03-01 Dsm Ip Assets Bv cepas de talaromyces e composições de enzima.
CA2779796A1 (en) 2009-11-04 2011-05-12 Dsm Ip Assets B.V. Talaromyces transformants
EP2552934B1 (en) 2010-03-30 2015-07-15 Novozymes A/S Crystal metabolite recovery
KR101013456B1 (ko) * 2010-11-24 2011-02-14 주식회사 그린바이오텍 심플리실리움 라멜리콜라 bcp 균주 배양용 배지 조성물 및 이의 배양방법
WO2012088276A2 (en) * 2010-12-21 2012-06-28 J3H, Inc Phospholipid production and composition manipulation through media manipulation
CA2823270A1 (en) 2011-01-31 2012-08-09 Novozymes A/S Use of browned glucose as a feed substrate
EP2683732B1 (en) 2011-03-11 2016-08-24 DSM IP Assets B.V. Vector-host system
US10160989B2 (en) * 2011-05-02 2018-12-25 Renewuel Llc System and method of co-cultivating microalgae with fungus
EP2742145A1 (en) 2011-08-12 2014-06-18 Novozymes A/S Reduction of culture viscosity by manganese addition
US20150197760A1 (en) 2012-06-19 2015-07-16 Dsm Ip Assets B.V. Promoters for expressing a gene in a cell
BR112014029846A2 (pt) 2012-07-06 2017-06-27 Novozymes As método de inativação da célula hospedeira microbiana em um caldo de fermentação
EP2889369B1 (en) * 2012-08-24 2020-03-25 Yamaguchi University Yeast culture medium
CN104797590A (zh) 2012-11-01 2015-07-22 诺维信公司 用于去除dna的方法
EP3447136B1 (en) 2013-02-04 2020-05-13 DSM IP Assets B.V. Carbohydrate degrading polypeptide and uses thereof
US9943545B2 (en) 2013-03-15 2018-04-17 Fate Therapeutics, Inc. Stem cell culture media and methods of enhancing cell survival
WO2014202620A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202624A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202622A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202621A1 (en) 2013-06-20 2014-12-24 Dsm Ip Assets B.V. Carbohydrate degrading polypeptide and uses thereof
EP2826384A1 (de) 2013-07-16 2015-01-21 Evonik Industries AG Verfahren zur Trocknung von Biomasse
JP6393898B2 (ja) * 2014-08-03 2018-09-26 国立大学法人 奈良先端科学技術大学院大学 酵母の培養方法
CA2958439C (en) 2014-10-02 2022-09-20 Evonik Industries Ag Feedstuff of high abrasion resistance and good stability in water, containing pufas
BR112017005388B1 (pt) 2014-10-02 2022-09-13 Evonik Operations Gmbh Alimento para animais contendo biomassa de aurantiochytrium
DK3200606T3 (da) 2014-10-02 2021-06-21 Evonik Operations Gmbh Fremgangsmåde til fremstilling af et fodermiddel, der indeholder pufa'er, ved ekstrusion af en biomasse, der indeholder pufa'er, af typen labyrinthulomycetes
BR112017006838B1 (pt) 2014-10-02 2021-07-06 Evonik Operations Gmbh Processo para produzir um alimento para animais compreendendo biomassa contendo pufa, alimento para animais e método para criar animais
WO2017097869A1 (en) 2015-12-09 2017-06-15 Basf Se Method of purifying a protein from fermentation solids under desorbing conditions
CN105505829A (zh) * 2016-01-20 2016-04-20 黑龙江省中医药科学院 发酵类中药优势菌群选择性培养基及其制备方法和发酵类中药优势菌的筛选方法
MA44657A (fr) 2016-04-12 2019-02-20 Wim De Laat Consultancy B V Souches de pseudomonas et consortiums correspondantes destinées à être utilisées dans la protection contre des maladies de plante
US20190292514A1 (en) 2016-07-14 2019-09-26 Basf Se Fermentation medium comprising chelating agent
JP2018023356A (ja) * 2016-08-04 2018-02-15 三洋化成工業株式会社 有用物質の生産方法
KR102435384B1 (ko) 2016-08-11 2022-08-24 더 프로틴 브루어리 비.브이. 호열성 균류(thermophilic fungi)로부터의 단세포 단백질
CN111032856A (zh) 2017-08-07 2020-04-17 诺维信公司 基于pH的FCA控制的用途
CN110452945B (zh) * 2018-05-07 2023-06-23 华东理工大学 利用红色糖多孢菌发酵生产红霉素的方法
WO2020169563A1 (en) 2019-02-20 2020-08-27 Basf Se Industrial fermentation process for bacillus using defined medium and magnesium feed
CN114127256A (zh) * 2019-02-20 2022-03-01 巴斯夫欧洲公司 用确定成分培养基和微量元素补料的芽孢杆菌工业发酵工艺
FI3983425T3 (fi) 2019-06-13 2025-11-19 Basf Se Menetelmä proteiinin talteen ottamiseksi käymisliemestä käyttämällä divalenttista kationia
CN110283854B (zh) * 2019-08-08 2021-07-16 内蒙古金达威药业有限公司 一种发酵培养基及其应用和利用三孢布拉霉菌发酵制备番茄红素的方法
JP2023506284A (ja) 2019-12-19 2023-02-15 ビーエーエスエフ ソシエタス・ヨーロピア ファインケミカルを生成する際の空時収率、炭素変換効率、及び炭素基質適応性の増加
MX2022007714A (es) 2019-12-20 2022-07-19 Basf Se Disminucion de la toxicidad de terpenos y aumento de la posible produccion en microorganismos.
KR102264895B1 (ko) * 2019-12-27 2021-06-15 명지대학교 산학협력단 메탄올을 소비하는 Aspergillus 균주를 이용한 유기산 생산 공정
US20230212634A1 (en) 2020-01-14 2023-07-06 The Protein Brewery B.V. Expression of Ovalbumin and its Natural Variants
WO2021148592A1 (en) 2020-01-23 2021-07-29 The Protein Brewery B.V. Use of a defoamer for maintaining dispersed morphology in submerged fungal fermentation
MX2022011034A (es) 2020-03-06 2022-10-13 The Protein Brewery B V Pasteurizacion de biomasa microbiana apta para aplicaciones alimentarias.
US20230139404A1 (en) 2020-03-06 2023-05-04 The Protein Brewery B.V. Improved single-cell protein production using antioxidants
CN111548944B (zh) * 2020-06-05 2022-06-14 福建省农业科学院植物保护研究所 一种促进莱氏绿僵菌产孢的固体发酵培养基及其制备方法和应用
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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3700558A (en) * 1967-11-20 1972-10-24 Lepetit Spa Production of l-tryptophan by fermentation
FR2280709A1 (fr) * 1974-07-30 1976-02-27 Ici Ltd Production de glucose isomerase
US4556559A (en) * 1974-04-20 1985-12-03 Beecham Group P.L.C. Antibiotics
US5494808A (en) * 1994-09-15 1996-02-27 Merck & Co., Inc. Defined medium OMPC fermentation process

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3205150A (en) * 1961-11-27 1965-09-07 Ca Nat Research Council Hydroxy fatty acid production
US4164445A (en) * 1975-03-27 1979-08-14 E. R. Squibb & Sons, Inc. Ethanol as the major source of carbon and energy in penicillin production
US4077842A (en) * 1976-03-19 1978-03-07 Cory Robert Paul Stabilized glucose isomerase enzyme concentrate
US4231938A (en) * 1979-06-15 1980-11-04 Merck & Co., Inc. Hypocholesteremic fermentation products and process of preparation
GR69216B (enExample) * 1979-06-15 1982-05-07 Merck & Co Inc
US4348481A (en) * 1979-11-29 1982-09-07 Institute Po Microbiologia Method of obtaining glucose isomerase
US4374929A (en) * 1980-07-14 1983-02-22 Standard Oil Company (Indiana) Production of xanthan gum from a chemically defined medium introduction
JPS59205979A (ja) * 1983-05-11 1984-11-21 Agency Of Ind Science & Technol 微生物菌体の製造方法
AR245221A1 (es) * 1984-10-27 1993-12-30 Beecham Group Plc Un metodo para la produccion de acido clavulanico por fermentacion de s. clavuligerus
JP2746371B2 (ja) * 1987-12-21 1998-05-06 サントリー株式会社 ビスホモ−γ−リノレン酸及びこれを含有する脂質の製造方法
EP0351029B1 (en) * 1988-07-15 2002-03-06 Genencor International, Inc. Novel glucose isomerase enzymes and their use
US5290690A (en) * 1988-07-15 1994-03-01 Plant Genetic Systems Methods and means for controlling the stability of proteins
US5376536A (en) * 1988-07-15 1994-12-27 Gist-Brocades, N.V. Glucose isomerase enzymes and their use
CH680448A5 (enExample) * 1990-01-17 1992-08-31 Nestle Sa
US5658767A (en) * 1991-01-24 1997-08-19 Martek Corporation Arachidonic acid and methods for the production and use thereof
US5318896A (en) * 1991-09-11 1994-06-07 Merck & Co., Inc. Recombinant expandase bioprocess for preparing 7-aminodesacetoxy cephalosporanic acid (7-ADCA)
NZ245713A (en) * 1992-02-10 1994-12-22 Novopharm Ltd Production of the antibiotic lovastatin from genetically engineered aspergillus strains
GB9220670D0 (en) * 1992-09-30 1992-11-11 Unilever Plc Cosmetic composition
FR2700552B1 (fr) * 1993-01-19 1995-04-21 Pernod Ricard Mutants de Phaffia rhodozyma, procédé de production de beta-carotène et utilisation de biomasse riche en beta-carotène.
WO1995004148A1 (en) * 1993-07-30 1995-02-09 Gist-Brocades B.V. Process for the efficient production of 7-adca via 2-(carboxyethylthio)acetyl-7-adca and 3-(carboxymethylthio)propionyl-7-adca
JP2677949B2 (ja) * 1993-08-26 1997-11-17 常盤薬品工業株式会社 アラキドン酸含有健康食品
US5583019A (en) * 1995-01-24 1996-12-10 Omegatech Inc. Method for production of arachidonic acid
US6432468B1 (en) * 1995-05-30 2002-08-13 Suntory Limited Domestic fowl eggs having a high content of highly unsaturated fatty acid, their production process and their use
US5731165A (en) * 1995-06-02 1998-03-24 Gist-Brocades, B.V. Process for the production of 7-ADCA via expandase activity on penicillin G
SI9500238A (en) * 1995-07-27 1997-02-28 Krka Tovarna Zdravil Procedure for the production of lovastatin
US5989877A (en) * 1995-08-03 1999-11-23 Gist-Brocades B.V. Selective process for the deacylation of acylated compounds
US20030143659A1 (en) * 1996-03-28 2003-07-31 Hendrik Louis Bijl Process for the preparation of a granular microbial biomass and isolation of a compound thereform
US6255505B1 (en) * 1996-03-28 2001-07-03 Gist-Brocades, B.V. Microbial polyunsaturated fatty acid containing oil from pasteurised biomass
KR100576576B1 (ko) * 1997-02-20 2006-05-04 디에스엠 아이피 어셋츠 비.브이. 화학적 합성 배지를 이용하는 가치있는 화합물들의 산업적 규모의 발효적 생산
DE69840022D1 (de) * 1997-03-04 2008-10-30 Suntory Ltd Verfahren zur herstellung von hochungesättigten fettsäuren und hochungesättigte fettsäuren enthaltendes lipid

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3700558A (en) * 1967-11-20 1972-10-24 Lepetit Spa Production of l-tryptophan by fermentation
US4556559A (en) * 1974-04-20 1985-12-03 Beecham Group P.L.C. Antibiotics
FR2280709A1 (fr) * 1974-07-30 1976-02-27 Ici Ltd Production de glucose isomerase
US5494808A (en) * 1994-09-15 1996-02-27 Merck & Co., Inc. Defined medium OMPC fermentation process

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Mao, W. et al.: "High production of alkaline protease by Bacillus licheniformis in a fed-batch fermentation using a synthetic medium" Journal of Industrial Microbiology vol.11, 1-6, 1992 *

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