CY2021010I2 - 4-ιμιδαζοπυριδαζιν-1-υλ-βενζαμιδια και 4-ιμιδαζοτριαζιν-1-υλ-βενζαμιδια ως αναστολεις βτκ - Google Patents

4-ιμιδαζοπυριδαζιν-1-υλ-βενζαμιδια και 4-ιμιδαζοτριαζιν-1-υλ-βενζαμιδια ως αναστολεις βτκ

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Publication number
CY2021010I2
CY2021010I2 CY2021010C CY2021010C CY2021010I2 CY 2021010 I2 CY2021010 I2 CY 2021010I2 CY 2021010 C CY2021010 C CY 2021010C CY 2021010 C CY2021010 C CY 2021010C CY 2021010 I2 CY2021010 I2 CY 2021010I2
Authority
CY
Cyprus
Prior art keywords
benzamides
imidazotriazin
imidazopyridazin
btk inhibitors
btk
Prior art date
Application number
CY2021010C
Other languages
Greek (el)
English (en)
Other versions
CY2021010I1 (el
Original Assignee
Merck Sharp & Dohme B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47557677&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY2021010(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Sharp & Dohme B.V. filed Critical Merck Sharp & Dohme B.V.
Publication of CY2021010I1 publication Critical patent/CY2021010I1/el
Publication of CY2021010I2 publication Critical patent/CY2021010I2/el

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
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  • Obesity (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CY2021010C 2011-07-19 2021-04-21 4-ιμιδαζοπυριδαζιν-1-υλ-βενζαμιδια και 4-ιμιδαζοτριαζιν-1-υλ-βενζαμιδια ως αναστολεις βτκ CY2021010I2 (el)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161509397P 2011-07-19 2011-07-19
EP11174578 2011-07-19
EP12733505.7A EP2734522B1 (en) 2011-07-19 2012-07-11 4-imidazopyridazin-1-yl-benzamides and 4-imidazotriazin-1-yl-benzamides as btk-inhibitors
PCT/EP2012/063552 WO2013010868A1 (en) 2011-07-19 2012-07-11 4 - imidazopyridazin- 1 -yl-benzamides and 4 - imidazotriazin- 1 - yl - benzamides as btk- inhibitors

Publications (2)

Publication Number Publication Date
CY2021010I1 CY2021010I1 (el) 2021-06-25
CY2021010I2 true CY2021010I2 (el) 2021-06-25

Family

ID=47557677

Family Applications (2)

Application Number Title Priority Date Filing Date
CY2021010C CY2021010I2 (el) 2011-07-19 2021-04-21 4-ιμιδαζοπυριδαζιν-1-υλ-βενζαμιδια και 4-ιμιδαζοτριαζιν-1-υλ-βενζαμιδια ως αναστολεις βτκ
CY20211101020T CY1125613T1 (el) 2011-07-19 2021-11-24 4-ιμιδαζοπυριδαζιν-1-υλ-βενζαμιδια και 4- ιμιδαζοτριαζιν-1-υλ-βενζαμιδια ως αναστολεις βτκ

Family Applications After (1)

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CY20211101020T CY1125613T1 (el) 2011-07-19 2021-11-24 4-ιμιδαζοπυριδαζιν-1-υλ-βενζαμιδια και 4- ιμιδαζοτριαζιν-1-υλ-βενζαμιδια ως αναστολεις βτκ

Country Status (38)

Country Link
US (7) US9290504B2 (h)
EP (4) EP3689878B1 (h)
JP (6) JP5826931B2 (h)
KR (2) KR101802689B1 (h)
CN (2) CN103889987B (h)
AU (4) AU2012285987C1 (h)
BR (1) BR112014001255B1 (h)
CA (1) CA2841886C (h)
CL (1) CL2014000130A1 (h)
CO (1) CO6940411A2 (h)
CR (1) CR20140030A (h)
CY (2) CY2021010I2 (h)
DK (2) DK2734522T3 (h)
DO (1) DOP2014000008A (h)
EA (2) EA034558B1 (h)
EC (1) ECSP14013217A (h)
ES (3) ES2904707T3 (h)
GT (1) GT201400009A (h)
HR (2) HRP20212021T1 (h)
HU (3) HUE041987T2 (h)
IL (3) IL230511B (h)
IN (1) IN2014CN00408A (h)
LT (1) LT2734522T (h)
MA (1) MA35348B1 (h)
MX (1) MX342983B (h)
MY (1) MY192354A (h)
PE (1) PE20141681A1 (h)
PH (2) PH12014500148A1 (h)
PL (2) PL2734522T3 (h)
PT (1) PT3689878T (h)
RS (2) RS58177B1 (h)
SG (1) SG10201605913VA (h)
SI (2) SI2734522T1 (h)
SM (2) SMT201900029T1 (h)
TN (1) TN2014000027A1 (h)
UA (1) UA115312C2 (h)
WO (1) WO2013010868A1 (h)
ZA (1) ZA202109164B (h)

Families Citing this family (116)

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US20120101113A1 (en) * 2007-03-28 2012-04-26 Pharmacyclics, Inc. Inhibitors of bruton's tyrosine kinase
MX342405B (es) 2010-06-03 2016-09-28 Pharmacyclics Inc El uso de inhibidores de la tirosina quinasa de bruton (btk).
US9376438B2 (en) 2011-05-17 2016-06-28 Principia Biopharma, Inc. Pyrazolopyrimidine derivatives as tyrosine kinase inhibitors
ES2604191T3 (es) 2011-05-17 2017-03-03 Principia Biopharma Inc. Inhibidores de tirosina quinasas
CA2841080A1 (en) 2011-07-13 2013-01-17 Pharmacyclics, Inc. Inhibitors of bruton's tyrosine kinase
DK2734522T3 (en) * 2011-07-19 2019-02-18 Merck Sharp & Dohme 4-IMIDAZOPYRIDAZIN-1-YL-BENZAMIDES AND 4-IMIDAZOTRIAZIN-1-YL-BENZAMIDES AS BTK INHIBITORS
EP2548877A1 (en) 2011-07-19 2013-01-23 MSD Oss B.V. 4-(5-Membered fused pyridinyl)benzamides as BTK-inhibitors
CA2879570A1 (en) 2012-07-24 2014-01-30 Pharmacyclics, Inc. Mutations associated with resistance to inhibitors of bruton's tyrosine kinase (btk)
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UA115312C2 (uk) 2017-10-25
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