HRP20171579T8 - Antigljivična sredstva i njihova upotreba - Google Patents

Antigljivična sredstva i njihova upotreba

Info

Publication number
HRP20171579T8
HRP20171579T8 HRP20171579TT HRP20171579T HRP20171579T8 HR P20171579 T8 HRP20171579 T8 HR P20171579T8 HR P20171579T T HRP20171579T T HR P20171579TT HR P20171579 T HRP20171579 T HR P20171579T HR P20171579 T8 HRP20171579 T8 HR P20171579T8
Authority
HR
Croatia
Prior art keywords
antifungal agents
antifungal
agents
Prior art date
Application number
HRP20171579TT
Other languages
English (en)
Inventor
Kenneth Duke James
Christopher Patrick Laudeman
Navdeep Balkrishna Malkar
Balasingam Radhakrishnan
Original Assignee
Cidara Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cidara Therapeutics, Inc. filed Critical Cidara Therapeutics, Inc.
Publication of HRP20171579T1 publication Critical patent/HRP20171579T1/hr
Publication of HRP20171579T8 publication Critical patent/HRP20171579T8/hr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/60Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Otolaryngology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HRP20171579TT 2011-03-03 2017-10-17 Antigljivična sredstva i njihova upotreba HRP20171579T8 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161448807P 2011-03-03 2011-03-03
PCT/US2012/027451 WO2012119065A2 (en) 2011-03-03 2012-03-02 Antifungal agents and uses thereof
EP12751994.0A EP2680873B1 (en) 2011-03-03 2012-03-02 Antifungal agents and uses thereof

Publications (2)

Publication Number Publication Date
HRP20171579T1 HRP20171579T1 (hr) 2018-02-09
HRP20171579T8 true HRP20171579T8 (hr) 2018-12-14

Family

ID=46758514

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20171579TT HRP20171579T8 (hr) 2011-03-03 2017-10-17 Antigljivična sredstva i njihova upotreba

Country Status (18)

Country Link
US (5) US8722619B2 (hr)
EP (2) EP2680873B1 (hr)
JP (4) JP5809296B2 (hr)
CN (2) CN106279369B (hr)
CA (2) CA3053850A1 (hr)
CY (1) CY1119709T1 (hr)
DK (1) DK2680873T3 (hr)
ES (1) ES2645074T3 (hr)
FI (1) FIC20240022I1 (hr)
HR (1) HRP20171579T8 (hr)
HU (1) HUE036778T2 (hr)
LT (1) LT2680873T (hr)
NO (1) NO2680873T3 (hr)
PL (1) PL2680873T3 (hr)
PT (1) PT2680873T (hr)
RS (1) RS56426B1 (hr)
SI (1) SI2680873T1 (hr)
WO (1) WO2012119065A2 (hr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS56426B1 (sr) 2011-03-03 2018-01-31 Cidara Therapeutics Inc Antigljivična sredstva i njihova upotreba
JP6117907B2 (ja) * 2012-03-19 2017-04-19 シダラ セラピューティクス インコーポレーテッド エキノキャンディン系化合物のための投与レジメン
US20160213742A1 (en) * 2013-09-04 2016-07-28 Cidara Therapeutics, Inc. Compositions and methods for the treatment of fungal infections
EP3136864A4 (en) * 2014-04-28 2017-12-27 University of Central Florida Research Foundation, Inc. Compositions, methods of making a composition, and methods of use
WO2016201283A1 (en) * 2015-06-12 2016-12-15 Cidara Therapeutics, Inc. Antifungal agents
US20180256673A1 (en) * 2015-09-16 2018-09-13 Cidara Therapeutics, Inc. Methods for treating fungal infections
CN106674333B (zh) * 2015-11-06 2020-10-27 博瑞生物医药(苏州)股份有限公司 一种环肽类抗真菌化合物及其制备方法
US10369188B2 (en) 2016-01-08 2019-08-06 Cidara Therapeutics, Inc. Methods for preventing and treating pneumocystis infections
EP3430400B1 (en) 2016-03-16 2023-06-21 Cidara Therapeutics, Inc. Dosing regimens for treatment of fungal infections
US20210002346A1 (en) * 2016-11-29 2021-01-07 Cidara Therapeutics, Inc Methods for preventing fungal infections
WO2018144600A1 (en) * 2017-01-31 2018-08-09 Cidara Therapeutics, Inc. Methods for treating fungal infections
CA3069423A1 (en) * 2017-07-12 2019-01-17 Cidara Therapeutics, Inc. Formulations for the treatment of fungal infections
JP7373508B2 (ja) * 2018-06-15 2023-11-02 シダラ セラピューティクス インコーポレーテッド エキノカンジン抗真菌剤の合成
WO2020086931A1 (en) * 2018-10-25 2020-04-30 Cidara Therapeutics, Inc. Polymorph of echinocandin antifungal agent
EP4063381A4 (en) 2019-12-06 2023-04-26 Shanghai Senhui Medicine Co., Ltd. ECHINOCANDIN ANALOGS AND METHOD FOR PREPARING THEM
WO2022253297A1 (zh) 2021-06-03 2022-12-08 上海森辉医药有限公司 一种阿尼芬净衍生物的制备方法
CN116903706B (zh) * 2023-06-13 2024-05-17 深圳市祥根生物有限公司 一种棘白菌素类药物及其制备方法和用途

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6030944A (en) * 1991-10-01 2000-02-29 Merck & Co., Inc. Cyclohexapeptidyl bisamine compounds
US5399552A (en) 1991-10-17 1995-03-21 Merck & Co, Inc Antibiotic peptides bearing aminoalkylthioether moieties
US5378804A (en) 1993-03-16 1995-01-03 Merck & Co., Inc. Aza cyclohexapeptide compounds
US6268338B1 (en) 1993-04-30 2001-07-31 Merck & Co., Inc. Cyclohexapeptidyl amine compounds
US5948753A (en) 1993-05-04 1999-09-07 Merck & Co., Inc. Cyclohexapeptidyl propanolamine compounds
WO1994025045A1 (en) 1993-05-04 1994-11-10 Merck & Co., Inc. Cyclohexapeptidyl aminoalkyl ethers
AU7874494A (en) * 1993-09-22 1995-04-10 Merck & Co., Inc. Antifungal and anti-pneumocystis compounds, compositions containing such compounds, and methods of use
US5541160A (en) * 1994-04-04 1996-07-30 Merck & Co., Inc. Antifungal and anti-pneumocystis compounds, compositions containing such compounds, and methods of use
US5514651A (en) * 1994-09-16 1996-05-07 Merck & Co., Inc. Aza cyclohexapeptide compounds
US5516756A (en) 1994-10-31 1996-05-14 Merck & Co., Inc. Aza cyclohexapeptide compounds
EP0805685B1 (en) 1995-01-26 2001-09-26 Merck & Co., Inc. Novel antifungal cyclohexapeptides
US5652213A (en) * 1995-05-26 1997-07-29 Eli Lilly And Company Cyclic peptide antifungal agents
ES2272096T3 (es) * 1998-12-09 2007-04-16 Eli Lilly And Company Purificacion de compuestos ciclopeptidicos de equinocandina.
US6248363B1 (en) 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
EP1156784A1 (en) 1999-03-03 2001-11-28 Eli Lilly And Company Processes for making pharmaceutical oral ecb formulations and compositions
US6610822B2 (en) 2000-09-01 2003-08-26 Merck & Co., Inc. Purification process
US6991800B2 (en) 2002-06-13 2006-01-31 Vicuron Pharmaceuticals Inc. Antifungal parenteral products
DE602004010915T2 (de) * 2003-07-22 2008-12-11 Theravance, Inc., South San Francisco Verwendung eines antimykotischen echinocandin-mittels in kombination mit einem antibakteriellen glycopeptid-mittel
WO2007113386A1 (en) * 2006-03-31 2007-10-11 Karyon-Ctt Ltd Peptide conjugates
US20090238867A1 (en) 2007-12-13 2009-09-24 Scott Jenkins Nanoparticulate Anidulafungin Compositions and Methods for Making the Same
GB0817121D0 (en) 2008-09-18 2008-10-29 Univ St Andrews Anti-fungal therapy
WO2010128096A1 (en) * 2009-05-07 2010-11-11 Dsm Ip Assets B.V. Method for the preparation of cyclopeptides
JP2013503179A (ja) 2009-08-27 2013-01-31 シーチェイド ファーマシューティカルズ,インコーポレーテッド エキノキャンディン誘導体
WO2011089214A1 (en) 2010-01-22 2011-07-28 Ascendis Pharma As Carrier-linked carbamate prodrug linkers
RS56426B1 (sr) 2011-03-03 2018-01-31 Cidara Therapeutics Inc Antigljivična sredstva i njihova upotreba

Also Published As

Publication number Publication date
RS56426B1 (sr) 2018-01-31
US9217014B2 (en) 2015-12-22
JP5809296B2 (ja) 2015-11-10
US20160075740A1 (en) 2016-03-17
CN103889221A (zh) 2014-06-25
US20150024997A1 (en) 2015-01-22
LT2680873T (lt) 2017-11-27
JP2014516339A (ja) 2014-07-10
EP2680873A2 (en) 2014-01-08
JP2018118977A (ja) 2018-08-02
HUE036778T2 (hu) 2018-07-30
PT2680873T (pt) 2017-11-01
CA2865791A1 (en) 2012-09-07
CN103889221B (zh) 2016-08-31
JP2016029052A (ja) 2016-03-03
CY1119709T1 (el) 2018-06-27
EP2680873B1 (en) 2017-08-09
CA2865791C (en) 2019-10-08
WO2012119065A2 (en) 2012-09-07
EP3192803B1 (en) 2020-12-09
CA3053850A1 (en) 2012-09-07
FIC20240022I1 (fi) 2024-06-19
US8722619B2 (en) 2014-05-13
US20220162263A1 (en) 2022-05-26
ES2645074T8 (es) 2018-09-28
HRP20171579T1 (hr) 2018-02-09
ES2645074T3 (es) 2017-12-04
US9676821B2 (en) 2017-06-13
EP3192803A1 (en) 2017-07-19
EP2680873A4 (en) 2015-08-26
WO2012119065A3 (en) 2014-03-13
NO2680873T3 (hr) 2018-01-06
CN106279369A (zh) 2017-01-04
PL2680873T3 (pl) 2018-01-31
JP2017132770A (ja) 2017-08-03
DK2680873T3 (en) 2017-10-30
JP6302108B2 (ja) 2018-03-28
SI2680873T1 (sl) 2017-12-29
US20170253635A1 (en) 2017-09-07
JP6111447B2 (ja) 2017-04-12
US20130244930A1 (en) 2013-09-19
CN106279369B (zh) 2020-02-11

Similar Documents

Publication Publication Date Title
HRP20171579T8 (hr) Antigljivična sredstva i njihova upotreba
IL233051A0 (en) Anti-phf-tau antibodies and uses thereof
PL2691443T3 (pl) Sprzężone lipomery i ich zastosowania
EP2552953A4 (en) FRIZZLED-BINDING SUBSTANCES AND ITS USES
IL229844B (en) Anti-psgl-1 antibodies and their use
HK1201454A1 (en) Therapeutic agents and uses thereof
HK1191034A1 (en) N-carboxyalkyl-auristatins and use thereof n-
IL231082A (en) Pyrimido compounds - pyridazinone and their use
EP2699272A4 (en) CONTRAST AGENTS AND USES THEREOF
EP2928875A4 (en) FUNGICIDE COMPOUND AND USES THEREOF
EP2688412A4 (en) INSECTICIDES AND APPLICATIONS THEREOF
HK1190713A1 (zh) 外用抗真菌劑
EP2688588A4 (en) FAST AND LONG-TERM IMMUNOLOGICAL THERAPEUTIC
EP2716359A4 (en) COMPLEX AND USES THEREOF
EP2697386A4 (en) DESIGN AND USE OF PEPDUCINE
HK1192116A1 (zh) 殺蟲組合物及其相關方法
GB201111775D0 (en) Compounds and uses thereof
EP2720536A4 (en) NEW AGENTS FOR COMBATING NAILS AND APPLICATIONS THEREOF
GB201106357D0 (en) Composition and uses thereof
EP2776064A4 (en) ANTAGONISTS OF PRO-VASOPRESSIN AND USES THEREOF
EP2693879A4 (en) MIGRASTATINES AND THEIR USES
EP2704579A4 (en) SCRAP CONTROL AND APPLICATIONS THEREOF
HK1254681A1 (zh) 抗真菌劑
EP2605770A4 (en) ANTIFUNGAL AGENTS AND USES THEREOF
HK1201692A1 (en) Antifungal agent