|
US3205220A
(en)
|
1961-10-26 |
1965-09-07 |
Lilly Co Eli |
Leurosidine and leurocristine and their production
|
|
US4762949A
(en)
|
1979-06-20 |
1988-08-09 |
University Of Illinois Foundation |
Acyl and carbamimidoyl alkanediamines
|
|
GB2058047B
(en)
|
1979-07-11 |
1983-09-21 |
Asahi Chemical Ind |
Amides and amidines
|
|
FR2461995A1
(fr)
|
1979-07-20 |
1981-02-06 |
Lcc Cice Cie Europ Compo Elect |
Transducteur magneto-electrique pour systeme d'enregistrement magnetique, et systeme d'enregistrement comportant un tel transducteur
|
|
US4950649A
(en)
|
1980-09-12 |
1990-08-21 |
University Of Illinois |
Didemnins and nordidemnins
|
|
US5137870A
(en)
|
1980-09-12 |
1992-08-11 |
The Board Of Trustees Of The University Of Illinois |
Didemnins and nordidemnins
|
|
US4782135A
(en)
|
1980-09-12 |
1988-11-01 |
Board Of Trustees, University Of Illinois |
Composition of matter and process
|
|
US4493796A
(en)
|
1980-09-12 |
1985-01-15 |
Board Of Trustees, Univ. Of Ill. |
Didemnins A, B, C, and derivatives thereof, as antiviral agents
|
|
DE3161556D1
(en)
|
1980-09-12 |
1984-01-05 |
Univ Illinois |
Novel antibiotics, derivatives thereof, processes for their extraction, and compositions containing them
|
|
US4548814A
(en)
|
1980-12-18 |
1985-10-22 |
The Board Of Trustees Of The University Of Illinois |
Composition of matter and process
|
|
JPS5922518A
(ja)
|
1982-07-29 |
1984-02-04 |
余合住金産業株式会社 |
洋服タンス
|
|
IT1153974B
(it)
|
1982-09-23 |
1987-01-21 |
Erba Farmitalia |
Composizioni farmacologiche a base di cisplatino e metodo per il loro ottenimento
|
|
US4855086A
(en)
|
1982-10-15 |
1989-08-08 |
Burroughs Wellcome Co. |
Novel pesticides, preparation and use
|
|
US4537883A
(en)
|
1982-11-12 |
1985-08-27 |
Mead Johnson & Company |
Lyophilized cyclophosphamide
|
|
JPS59225189A
(ja)
|
1983-06-03 |
1984-12-18 |
Shionogi & Co Ltd |
キノナミン誘導体およびその製造法
|
|
US4631149A
(en)
|
1983-07-25 |
1986-12-23 |
University Of Illinois |
Antiviral eudistomins from a marine tunicate
|
|
JPS6084288A
(ja)
|
1983-10-13 |
1985-05-13 |
Shionogi & Co Ltd |
シアノキノナミンアセテ−ト類およびその製造法
|
|
US4567253A
(en)
|
1984-02-03 |
1986-01-28 |
Tony Durst |
2-Substituted derivatives of podophyllotoxin and etoposide
|
|
JPS61109717A
(ja)
|
1984-11-02 |
1986-05-28 |
Teruhiko Beppu |
抗腫瘍剤
|
|
ATE68186T1
(de)
|
1984-12-28 |
1991-10-15 |
Conpharm Ab |
Verwendung von podophyllotoxin und dessen derivaten.
|
|
US4644072A
(en)
|
1985-04-12 |
1987-02-17 |
Bristol-Myers Company |
Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof
|
|
DE3684868D1
(de)
|
1985-09-20 |
1992-05-21 |
Cernitin Sa |
Verwendung von pflanzenpollenextrakten zur herstellung von das wachstum von tumorzellen hemmenden pharmazeutischen praeparaten und verfahren zu ihrer herstellung.
|
|
US4731377A
(en)
|
1986-01-31 |
1988-03-15 |
Harbor Branch Oceanographic Institute, Inc. |
Antitumor cyclic peroxides
|
|
US5256663A
(en)
|
1986-06-09 |
1993-10-26 |
The Board Of Trustees Of The University Of Illinois |
Compositions comprising ecteinascidins and a method of treating herpes simplex virus infections therewith
|
|
US5089273A
(en)
|
1986-06-09 |
1992-02-18 |
Board Of Trustees Of The University Of Illinois |
Ecteinascidins 729, 743, 745, 759A, 759B and 770
|
|
AU589282B2
(en)
|
1986-06-09 |
1989-10-05 |
University Of Illinois |
Ecteinascidins 729, 743, 745, 759a, 759b and 770
|
|
US5149804A
(en)
|
1990-11-30 |
1992-09-22 |
The Board Of Trustees Of The University Of Illinois |
Ecteinascidins 736 and 722
|
|
US4816450A
(en)
|
1986-09-15 |
1989-03-28 |
Duke University |
Inhibition of protein kinase C by long-chain bases
|
|
US4737510A
(en)
|
1986-09-30 |
1988-04-12 |
The Board Of Trustees Of The University Of Illinois |
Bioactive metabolites from the caribbean sponge agelas coniferin
|
|
US5093330A
(en)
|
1987-06-15 |
1992-03-03 |
Ciba-Geigy Corporation |
Staurosporine derivatives substituted at methylamino nitrogen
|
|
US4847246A
(en)
|
1987-09-11 |
1989-07-11 |
Wilson George R |
Antiviral compositions derived from fireflies and their methods of use
|
|
FR2623504B1
(fr)
|
1987-11-25 |
1990-03-09 |
Adir |
Nouveaux derives n-(vinblastinoyl-23) d'acide amino-1 methylphosphonique, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
|
|
US5559145A
(en)
|
1988-06-01 |
1996-09-24 |
Oxaco S.A. |
1,2,4-trioxane derivatives
|
|
EP0358418B1
(en)
|
1988-09-05 |
1992-12-16 |
Sankyo Company Limited |
Cyclic peptide, its preparation and its use in the treatment of cardiovascular disorders
|
|
WO1990005731A1
(en)
|
1988-11-24 |
1990-05-31 |
University Of Queensland |
Cytotoxic macromolecules
|
|
US5190876A
(en)
|
1988-12-27 |
1993-03-02 |
Emory University |
Method of modifying cellular differentiation and function and compositions therefor
|
|
CA2007507C
(en)
|
1989-02-03 |
1998-05-19 |
Yasuyuki Igarashi |
Sphingosine and n-methyl-sphingosine as inhibitor of cell growth
|
|
US5583160A
(en)
|
1989-02-03 |
1996-12-10 |
The Biomembrane Institute |
Methylsphingosine used to treat apoptosis
|
|
US4948791A
(en)
|
1989-04-10 |
1990-08-14 |
The Board Of Trustees Of The University Of Illinois |
Novel Cytotoxic cyclic depsipeptides from the tunicate trididemnum solidum
|
|
US4986988A
(en)
|
1989-05-18 |
1991-01-22 |
Arizona Board Of Regents |
Isolation and structural elucidation of the cytostatic linear depsipeptides dolastatin 13 and dehydrodolastatin 13
|
|
US20030148933A1
(en)
|
1990-10-01 |
2003-08-07 |
Pharma Mar S.A. |
Derivatives of dehydrodidemnin B
|
|
GB8922026D0
(en)
|
1989-09-29 |
1989-11-15 |
Pharma Mar Sa |
Novel anti-viral and cytotoxic agent
|
|
US5053559A
(en)
|
1989-12-29 |
1991-10-01 |
Oxaco S.A. |
Cleavage of 1,2,4-trioxanes
|
|
KR910014122A
(ko)
|
1990-01-19 |
1991-08-31 |
디께다 가즈히꼬 |
에토포시드-2-디메틸아미노 화합물의 동결건조 제제
|
|
JPH0539283A
(ja)
|
1991-01-31 |
1993-02-19 |
Suntory Ltd |
新規物質Ｓ−５９９１７ａ及びその製造方法
|
|
US5721352A
(en)
|
1991-02-19 |
1998-02-24 |
University Of Florida Research Foundation |
Entomopoxvirus expression system
|
|
DE4120327A1
(de)
|
1991-06-20 |
1992-12-24 |
Basf Ag |
Neue peptide, ihre herstellung und verwendung
|
|
US5336669A
(en)
|
1991-12-10 |
1994-08-09 |
Erbamont, Inc. |
Cyclophosphamide monohydrate and lactose
|
|
JPH05247055A
(ja)
|
1992-03-03 |
1993-09-24 |
Meiji Seika Kaisha Ltd |
スタウロスポリン誘導体及びそれを含有する抗腫瘍効果増強剤
|
|
GB9206244D0
(en)
|
1992-03-23 |
1992-05-06 |
Pharma Mar Sa |
Cytotoxic compound from a marine sponge
|
|
GB9212000D0
(en)
|
1992-06-05 |
1992-07-15 |
Univ Madrid Complutense |
New synthetic antitumoral compound
|
|
CA2140653A1
(en)
|
1992-08-12 |
1994-03-03 |
Irene Abraham |
Protein kinase inhibitors and related compounds combined with taxol
|
|
US5756734A
(en)
|
1992-09-11 |
1998-05-26 |
Pharmamar, S.A. |
Crambescidins: new antiviral and cytotoxic compounds from the sponge crambe crambe
|
|
ES2059259B1
(es)
|
1992-09-22 |
1995-10-01 |
Pharma Mar S A Pharmar |
Procedimiento de obtencion de nuevos areno (e)indoles utiles como intermedios en la sintesis de productos con actividad antitumoral.
|
|
US5580871A
(en)
|
1992-11-20 |
1996-12-03 |
The Dupont Merck Pharmaceutical Company |
4-Heteroaryl- 1,4-dihydropyridine compounds with calcium agonist and alpha1 -antagonist activity
|
|
GB9302046D0
(en)
|
1993-02-03 |
1993-03-24 |
Pharma Mar Sa |
Antiumoral compound-v
|
|
GB9302044D0
(en)
|
1993-02-03 |
1993-03-24 |
Pharma Mar Sa |
Cytotoxic compounds i
|
|
US6274551B1
(en)
|
1994-02-03 |
2001-08-14 |
Pharmamar, S.A. |
Cytotoxic and antiviral compound
|
|
US5569757A
(en)
|
1993-03-30 |
1996-10-29 |
Rinehart; Kenneth L. |
9-deazaadenosine and its 5'-α-D-glycopyranoside isolated from the cyanobacterium anabaena affinis strain VS-1
|
|
GB9308111D0
(en)
|
1993-04-20 |
1993-06-02 |
Pharma Gen S A |
Active compound from a stonge
|
|
US5556777A
(en)
|
1993-09-09 |
1996-09-17 |
Pharmamar, S.A. |
Immunosuppressive pharmaceutical compositions new biological activity from a marine agrobacterium sp.
|
|
US5478932A
(en)
|
1993-12-02 |
1995-12-26 |
The Board Of Trustees Of The University Of Illinois |
Ecteinascidins
|
|
US5462726A
(en)
|
1993-12-17 |
1995-10-31 |
Bristol-Myers Squibb Company |
Method of inhibiting side effects of solvents containing ricinoleic acid or castor oil or derivatives thereof employing a thromboxane A2 receptor antagonist and pharmaceutical compositions containing such solvents
|
|
US20040059112A1
(en)
|
1994-02-18 |
2004-03-25 |
Rinehart Kenneth L. |
Ecteinascidins
|
|
US5514708A
(en)
|
1994-02-18 |
1996-05-07 |
Pharmamar, S.A. |
Cytotoxic metabolites from Myriapora truncata
|
|
US5681813A
(en)
|
1994-04-06 |
1997-10-28 |
Pharma Mar, S.A. |
Thiodepsipeptide isolated from a marine actinomycete
|
|
ES2100124B1
(es)
|
1994-08-01 |
1998-04-01 |
Pharma Mar Sa |
Perfeccionamientos introducidos en la p.i. 9401697 por terpeno-quinonas con actividad antitumoral.
|
|
US5514705A
(en)
|
1994-09-07 |
1996-05-07 |
Pharmamar, S.A. |
Epidioxymanadic acids A and B
|
|
US5523456A
(en)
|
1994-09-29 |
1996-06-04 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
|
GB9422947D0
(en)
|
1994-11-14 |
1995-01-04 |
Univ Salamanca |
Immunosuppressive cyclolignan derivatives
|
|
GB9422946D0
(en)
|
1994-11-14 |
1995-01-04 |
Univ Salamanca |
Antineoplastic cyclolignan derivatives
|
|
GB9504662D0
(en)
|
1995-03-08 |
1995-04-26 |
Pharma Mar Sa |
Antitumour isocoumarins
|
|
US20010039041A1
(en)
|
1995-06-07 |
2001-11-08 |
Pharma Mar, S.A. |
Immunosuppressive sesbanimide compositions and methods of treatment using same
|
|
US5661175A
(en)
|
1995-06-20 |
1997-08-26 |
Kashman; Yoel |
Hemiasterlin and geodiamolide TA
|
|
US5852033A
(en)
|
1995-06-29 |
1998-12-22 |
Pharma Mar, S.A. |
Methods of treatment using lamellarin-class alkaloids
|
|
ES2102322B1
(es)
|
1995-07-13 |
1998-03-01 |
Pharma Mar Sa |
Procedimiento de preparacion de didemnina a.
|
|
US5681847A
(en)
|
1995-12-05 |
1997-10-28 |
Harbor Branch Oceanographic Institution, Inc. |
Methods of using discodermolide compounds
|
|
EP0821068A3
(en)
|
1996-03-29 |
1999-06-02 |
Rohm And Haas Company |
Novel sphingolipids and a process thereto
|
|
GB9608010D0
(en)
|
1996-04-18 |
1996-06-19 |
Pharma Mar Sa |
Trunkamide A
|
|
US6156724A
(en)
|
1996-06-07 |
2000-12-05 |
Rinehart; Kenneth L. |
Uses of didemnins as immunomodulating agents
|
|
US5721362A
(en)
|
1996-09-18 |
1998-02-24 |
President And Fellows Of Harvard College |
Process for producing ecteinascidin compounds
|
|
DE69723728T2
(de)
|
1996-10-24 |
2004-06-03 |
The Board Of Trustees For The University Of Illinois, Urbana |
Totalsynthese des amino hip analogen von didemnin a
|
|
WO1998017275A1
(en)
|
1996-10-24 |
1998-04-30 |
The Board Of Trustees Of The University Of Illinois |
Semi-synthetic studies toward didemnin analogues
|
|
GB9622427D0
(en)
|
1996-10-28 |
1997-01-08 |
Pharma Mar Sa |
Antimalarial drugs
|
|
US6028077A
(en)
|
1997-04-15 |
2000-02-22 |
Rinehart; Kenneth L. |
Crambescidin compounds
|
|
US6034058A
(en)
|
1997-04-15 |
2000-03-07 |
Rinehart; Kenneth L. |
Semi-synthetic alanyl dilemnin analogs
|
|
US6107520A
(en)
|
1997-04-15 |
2000-08-22 |
The Board Of Trustees Of The University Of Illinois |
Spisulosine compounds
|
|
US5985876A
(en)
|
1997-04-15 |
1999-11-16 |
Univ Illinois |
Nucleophile substituted ecteinascidins and N-oxide ecteinascidins
|
|
USRE38793E1
(en)
|
1997-04-15 |
2005-09-06 |
Rinehart Kenneth L |
Spisulosine compounds
|
|
US6800661B1
(en)
|
1997-04-15 |
2004-10-05 |
Board Of Trustees Of The University Of Illinois |
Spisulosine compounds
|
|
AUPO656597A0
(en)
|
1997-05-02 |
1997-05-29 |
Australian National University, The |
Preparation of therapeutic compounds
|
|
EP0981352B8
(en)
|
1997-05-07 |
2009-06-17 |
Pharma Mar, S.A. |
Use of aplidine for the treatment of cardiovascular diseases
|
|
GB9723206D0
(en)
|
1997-11-03 |
1998-01-07 |
Inst Biomar Sa |
New cytotoxic pyridoacridine alkaloids
|
|
US6420357B1
(en)
|
1997-12-23 |
2002-07-16 |
Instituto Biomar, S.A. |
Cytotoxic alkaloid derivatives including Asmarine A and B isolated from a sponge
|
|
GB9727301D0
(en)
|
1997-12-23 |
1998-02-25 |
Inst Biomar Sa |
Asmarine A and B: New cytotoxic alkaloids
|
|
GB9801741D0
(en)
|
1998-01-27 |
1998-03-25 |
Inst Biomar Sa |
New cytotoxic tris (oxazole)-containing macrolides
|
|
GB9803448D0
(en)
|
1998-02-18 |
1998-04-15 |
Pharma Mar Sa |
Pharmaceutical formulation
|
|
BR9909488B1
(pt)
|
1998-04-06 |
2011-02-08 |
|
ecteinascidinas semi-sintéticas e composição farmacêutica.
|
|
US6656948B2
(en)
|
1998-04-29 |
2003-12-02 |
Universidad Complutense De Madrid |
Cytotoxic compounds: derivatives of the pyrido[2,3,4-kl]acridine ring system
|
|
WO1999056535A1
(en)
|
1998-05-05 |
1999-11-11 |
Pharma Mar, S.A. |
Culture of sessile marine animals
|
|
RU2225864C2
(ru)
*
|
1998-05-11 |
2004-03-20 |
Фарма Мар, С.А. |
Метаболиты эктейнасцидина-743, фармацевтическая композиция на их основе и способы лечения
|
|
GB9810998D0
(en)
|
1998-05-21 |
1998-07-22 |
Univ Madrid Complutense |
Antitumour 1,5-diazaanthraquinones
|
|
US6124292A
(en)
|
1998-09-30 |
2000-09-26 |
President And Fellows Of Harvard College |
Synthetic analogs of ecteinascidin-743
|
|
GB9821975D0
(en)
|
1998-10-08 |
1998-12-02 |
Pharma Mar Sa |
New cytotoxic alkaloids
|
|
US6245759B1
(en)
|
1999-03-11 |
2001-06-12 |
Merck & Co., Inc. |
Tyrosine kinase inhibitors
|
|
MY164077A
(en)
|
1999-05-13 |
2017-11-30 |
Pharma Mar Sa |
Compositions and uses of et743 for treating cancer
|
|
GB9918178D0
(en)
|
2000-05-15 |
1999-10-06 |
Pharma Mar Sa |
Synthetic methods
|
|
AR035842A1
(es)
|
1999-05-14 |
2004-07-21 |
Pharma Mar Sa |
Metodo de hemisintesis para la formacion de compuestos intermediarios y derivados y de estructuras relacionadas con la ecteinascidina y de tetrahidroisoquinolinfenoles y compuestos intermediarios de aplicacion en dicho metodo
|
|
GB9915069D0
(en)
|
1999-06-28 |
1999-08-25 |
Inst Biomar Sa |
New indolocarbazole alkaloids from a marine actinomycete
|
|
US6635677B2
(en)
|
1999-08-13 |
2003-10-21 |
Case Western Reserve University |
Methoxyamine combinations in the treatment of cancer
|
|
NZ518847A
(en)
|
1999-11-15 |
2004-02-27 |
Pharma Mar S |
Aplidine treatment of cancers
|
|
US6686470B2
(en)
|
2000-01-19 |
2004-02-03 |
The Trustees Of Columbia University In The City Of New York |
Compounds of the saframycin-ecteinascidin series, uses, and synthesis thereof
|
|
GB0002952D0
(en)
|
2000-02-09 |
2000-03-29 |
Pharma Mar Sa |
Process for producing kahalalide F compounds
|
|
JP2003523338A
(ja)
|
2000-02-16 |
2003-08-05 |
ファルマ・マール・ソシエダード・アノニマ |
抗腫瘍活性を有するオキシ−及びアミノ−置換テトラヒドロフリル誘導体
|
|
US20030187075A1
(en)
|
2000-03-20 |
2003-10-02 |
Junichi Tanaka Keith |
Sponge antitumor compounds
|
|
BR0109958A
(pt)
|
2000-04-07 |
2003-05-27 |
Univ Pennsylvania |
Análogos de didemnina e tamandarina e métodos de preparação e uso deles
|
|
US6509315B1
(en)
|
2000-04-07 |
2003-01-21 |
The Trustees Of The University Of Pennsylvania |
Didemnin analogs and fragments and methods of making and using them
|
|
US7919493B2
(en)
|
2000-04-12 |
2011-04-05 |
Pharma Mar, S.A. |
Anititumoral ecteinascidin derivatives
|
|
PT1280809E
(pt)
|
2000-04-12 |
2005-11-30 |
Pharma Mar Sa |
Derivados antitumorais de ecteinascidina
|
|
GB0010799D0
(en)
|
2000-05-04 |
2000-06-28 |
Inst Biomar Sa |
Stolonoxides
|
|
MXPA02011319A
(es)
|
2000-05-15 |
2003-06-06 |
Pharma Mar Sa |
Analogos antitumorales de ecteinascidina 743.
|
|
US7420051B2
(en)
|
2000-05-15 |
2008-09-02 |
Pharma Mar, S.A. |
Synthetic process for the manufacture of an ecteinaschidin compound
|
|
GB0011927D0
(en)
|
2000-05-17 |
2000-07-05 |
Inst Biomar Sa |
New use of citreamicins
|
|
DE60131076T2
(de)
|
2000-06-06 |
2008-07-31 |
Pharma Mar, S.A., Tres Cantos |
Antitumorale verbindungen
|
|
GB0016020D0
(en)
|
2000-06-29 |
2000-08-23 |
Inst Biomar Sa |
New polyciclic xanthones and their use
|
|
UA76718C2
(uk)
|
2000-06-30 |
2006-09-15 |
Фарма Мар, С.А. |
Протипухлинні похідні аплідину
|
|
EP1299388B1
(en)
|
2000-07-11 |
2009-05-13 |
Pharma Mar, S.A. |
Variolin derivatives as anti-cancer agents
|
|
EP2275174B1
(en)
|
2000-07-13 |
2016-04-20 |
ReCor Medical, Inc. |
Thermal treatment apparatus with ultrasound energy application
|
|
GB0019117D0
(en)
|
2000-08-03 |
2000-09-27 |
Univ Barcelona |
Derivatives of variolin B
|
|
KR20030038812A
(ko)
|
2000-10-12 |
2003-05-16 |
파르마 마르, 에스.에이. |
암 치료 방법
|
|
MXPA03003230A
(es)
|
2000-10-12 |
2004-12-03 |
Pharma Mar Sa |
Tratamiento de canceres.
|
|
WO2002036145A2
(en)
|
2000-10-31 |
2002-05-10 |
Pharma Mar, S.A. |
Kahalalide f formulation
|
|
NZ525730A
(en)
|
2000-11-06 |
2004-12-24 |
Pharma Mar S |
Compositions for antitumour treatments containing Ecteinascidin 743
|
|
GB0030417D0
(en)
|
2000-12-13 |
2001-01-24 |
Pharma Mar Sa |
An anticancer lead compound isolated from a New Zealand ascidian
|
|
WO2002058688A1
(de)
|
2001-01-24 |
2002-08-01 |
Mestex Ag |
Verwendung von neurotoxischen substanzen für die herstellung eines mittels zur behandlung von gelenkschmerzen
|
|
IL156580A0
(en)
|
2001-01-25 |
2004-01-04 |
Bristol Myers Squibb Co |
A method for formulating an epothilone analog for parenteral use and pharmaceutical preparations including an epothilone analog
|
|
EP1360337A1
(en)
|
2001-02-09 |
2003-11-12 |
The Regents Of The University Of California |
Ecteinascidin family compounds: compositions and methods
|
|
GB0105745D0
(en)
|
2001-03-08 |
2001-04-25 |
Pharma Gen S A |
Immobilisation of ligands
|
|
GB0108234D0
(en)
|
2001-04-02 |
2001-05-23 |
Pharma Mar Sa |
Process for producing trunkamide A compounds
|
|
GB0116966D0
(en)
|
2001-07-11 |
2001-09-05 |
Pharma Mar Sa |
Anittumoral compounds
|
|
GB0117402D0
(en)
|
2001-07-17 |
2001-09-05 |
Pharma Mar Sa |
New antitumoral derivatives of et-743
|
|
GB0119243D0
(en)
|
2001-08-07 |
2001-10-03 |
Pharma Mar Sa |
Antitumoral analogs of ET-743
|
|
EP1435988A4
(en)
|
2001-10-19 |
2008-01-09 |
Pharmamar Sa |
IMPROVED USE OF ANTI-TUMORAL COMPOUND IN THE TREATMENT OF CANCER
|
|
WO2003033012A1
(en)
|
2001-10-19 |
2003-04-24 |
Pharma Mar, S.A. |
Kahalalide compounds for use in cancer therapy
|
|
US20050054555A1
(en)
|
2001-10-19 |
2005-03-10 |
Jose Jimeno |
Kahalalide compounds for use in cancer therapy
|
|
US20050004012A1
(en)
|
2001-10-19 |
2005-01-06 |
Ramon Mangues |
Use of aplidine for the treatment of pancreatic cancer
|
|
GB0202544D0
(en)
|
2002-02-04 |
2002-03-20 |
Pharma Mar Sa |
The synthesis of naturally occuring ecteinascidins and related compounds
|
|
US20040019027A1
(en)
|
2002-04-12 |
2004-01-29 |
Barry Forman |
Method of treating cerebrotendinous xanthomatosis
|
|
GB0217638D0
(en)
|
2002-07-30 |
2002-09-11 |
Pharma Mar Sa |
Total synthesis of myriaporones
|
|
ES2544527T3
(es)
|
2002-07-31 |
2015-09-01 |
Seattle Genetics, Inc. |
Conjugados de fármacos y su uso para tratar el cáncer, una enfermedad autoinmune o una enfermedad infecciosa
|
|
GB0218816D0
(en)
|
2002-08-13 |
2002-09-18 |
Pharma Mar Sa |
Antitumoral analogs of lamellarins
|
|
GB0218813D0
(en)
|
2002-08-13 |
2002-09-18 |
Pharma Mar Sa |
DNA sequences from an endosymbiont and their uses
|
|
US20040033940A1
(en)
|
2002-08-16 |
2004-02-19 |
Pharma Mar, S.A. |
Cyclic hepta-peptide derivative from colonial ascidians, lissoclinum SP
|
|
NZ539093A
(en)
|
2002-10-18 |
2007-10-26 |
Pharma Mar Sau |
4-methylhexanoic kahalaide F compound
|
|
GB0304367D0
(en)
|
2003-02-26 |
2003-04-02 |
Pharma Mar Sau |
Methods for treating psoriasis
|
|
GB0229793D0
(en)
|
2002-12-20 |
2003-01-29 |
Pharma Mar Sa |
The gene cluster involved in safracin biosynthesis and its uses for genetic engineering
|
|
GB0303940D0
(en)
|
2003-02-20 |
2003-03-26 |
Pharma Mar Sau |
Solid phase synthesis of antitumoral compounds
|
|
JP5356648B2
(ja)
|
2003-02-20 |
2013-12-04 |
シアトル ジェネティックス， インコーポレイテッド |
抗ｃｄ７０抗体−医薬結合体、ならびに癌および免疫障害の処置のためのそれらの使用
|
|
US7507708B2
(en)
|
2003-02-26 |
2009-03-24 |
Pharma Mar, S.A.U. |
Antitumoral compounds
|
|
CN100409895C
(zh)
|
2003-03-12 |
2008-08-13 |
法马马有限公司 |
用于治疗白血病和淋巴瘤的阿普立定组合
|
|
WO2004080477A1
(en)
|
2003-03-12 |
2004-09-23 |
Dana-Farber Cancer Institute, Inc. |
Aplidine for multiple myeloma treatment
|
|
CA2519234A1
(en)
|
2003-03-21 |
2004-10-07 |
Madeleine M. Joullie |
Tamandarin analogs and fragments thereof and methods of making and using
|
|
US8088387B2
(en)
|
2003-10-10 |
2012-01-03 |
Immunogen Inc. |
Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
|
|
GB0312407D0
(en)
|
2003-05-29 |
2003-07-02 |
Pharma Mar Sau |
Treatment
|
|
KR20060031809A
(ko)
|
2003-06-09 |
2006-04-13 |
더 리젠츠 오브 더 유니버시티 오브 미시간 |
암 치료 및 진단용 조성물 및 방법
|
|
GB0314726D0
(en)
|
2003-06-24 |
2003-07-30 |
Inst Biomar Sa |
New cytotoxic depsipeptides
|
|
AU2004263287B2
(en)
|
2003-07-25 |
2009-02-12 |
Novartis Ag |
Substituted lactams and their use as anti-cancer agents
|
|
GB0321066D0
(en)
|
2003-09-09 |
2003-10-08 |
Pharma Mar Sau |
New antitumoral compounds
|
|
DE602004018811D1
(de)
|
2003-10-09 |
2009-02-12 |
Abbott Lab |
Pyrrolidinylharnstoffderivate als angiogeneseinhibitoren
|
|
GB0324201D0
(en)
|
2003-10-15 |
2003-11-19 |
Pharma Mar Sau |
Improved antitumoral combinations
|
|
SI1689404T1
(sl)
|
2003-11-13 |
2009-02-28 |
Pharma Mar Sau |
Kombinacija et-743 s 5-fluorouracil pro zdravili za zdravljenje raka
|
|
AU2004291037A1
(en)
*
|
2003-11-14 |
2005-06-02 |
Pharma Mar, S.A. |
Combination therapy comprising the use of ET-743 and paclitaxel for treating cancer
|
|
GB0326486D0
(en)
|
2003-11-14 |
2003-12-17 |
Pharma Mar Sau |
Combination treatment
|
|
DE102004011809A1
(de)
|
2004-03-11 |
2005-09-29 |
Robert Bosch Gmbh |
Magnetsensoranordnung
|
|
GB0408958D0
(en)
|
2004-04-22 |
2004-05-26 |
Pharma Mar Sa |
Convergent synthesis for kahalalide compounds
|
|
WO2005118584A2
(en)
|
2004-05-26 |
2005-12-15 |
Axys Pharmaceuticals, Inc. |
Saframycin analogs as therapeutic agents in the treatment of cancer
|
|
US7446196B2
(en)
|
2004-06-03 |
2008-11-04 |
Kosan Biosciences, Incorporated |
Leptomycin compounds
|
|
JP2008505862A
(ja)
|
2004-07-09 |
2008-02-28 |
ファルマ、マール、ソシエダード、アノニマ |
予後分子マーカー
|
|
CN101068596A
(zh)
|
2004-09-29 |
2007-11-07 |
法马马私人股份有限公司 |
艾可特耐思地作抗炎药
|
|
UA87877C2
(en)
|
2004-10-26 |
2009-08-25 |
Фарма Мар С.А., Сосьедад Униперсональ |
Pegylated liposomal doxorubicin in combination with ecteinescidin 743
|
|
BRPI0517238B1
(pt)
|
2004-10-29 |
2021-11-09 |
Pharma Mar, S.A. |
Composições que compreendem ecteinascidina e um dissacarídeo, método para produzir um frasco que contém a referida composição e para preparar uma solução para infusão intravenosa e uso da referida solução
|
|
EP1817059A2
(en)
|
2004-12-01 |
2007-08-15 |
Genentech, Inc. |
Conjugates of 1,8-bis-naphthalimides with an antibody
|
|
WO2006066183A2
(en)
|
2004-12-16 |
2006-06-22 |
Axys Pharmaceuticals, Inc. |
Novel saframycin analogs as therapeutic agents
|
|
US20100216817A1
(en)
|
2005-05-03 |
2010-08-26 |
Pharma Mar Sa |
Antitumoral Tetrahydro-Pyrimidines
|
|
GB0515673D0
(en)
|
2005-08-01 |
2005-09-07 |
Pharma Mar Sa |
Antitumoral compounds
|
|
CN101278050A
(zh)
|
2005-08-02 |
2008-10-01 |
马尔药品公司 |
参与噻可拉林生物合成的基因和噻可拉林的异源产生
|
|
GB0522082D0
(en)
|
2005-10-31 |
2005-12-07 |
Pharma Mar Sa |
Formulations
|
|
GB0523098D0
(en)
|
2005-11-14 |
2005-12-21 |
Pharma Mar Sa |
Antitumoral compounds
|
|
WO2007062413A2
(en)
|
2005-11-25 |
2007-05-31 |
University Of Medicine And Dentistry Of New Jersey |
Use of parp-1 inhibitors
|
|
ES2276629B1
(es)
|
2005-12-15 |
2009-04-01 |
Pharma Mar, S.A. |
Compuestos antitumorales.
|
|
ES2288107B1
(es)
|
2006-01-27 |
2008-11-01 |
Fundacion Imabis Instituto Mediterraneo Para El Avance De La Biotecnologia Y La Investigacion Sanita |
Derivados aciclicos saturados e insaturados de cadena larga de sulfamidas como activadores especificos de receptores ppar-alfa.
|
|
EP2029155B1
(en)
|
2006-02-28 |
2016-04-13 |
Pharma Mar S.A. |
Improved treatment of multiple myeloma
|
|
EP2023931A2
(en)
|
2006-05-12 |
2009-02-18 |
Pharma Mar S.A. |
Anticancer treatments with a combination of docetaxel and ecteinascidin
|
|
EP1864682A1
(en)
|
2006-06-09 |
2007-12-12 |
Sanofi-Aventis |
Leptomycin derivatives
|
|
PL2032551T3
(pl)
|
2006-06-16 |
2012-01-31 |
Pharma Mar Sa |
Przeciwnowotworowe związki dihydropiran-2-onu
|
|
US20100240595A1
(en)
|
2007-10-19 |
2010-09-23 |
Pharma Mar ,S.A. |
Improved Antitumoral Treatments
|
|
AU2008313634A1
(en)
|
2007-10-19 |
2009-04-23 |
Pharma Mar, S.A. |
Prognostic molecular markers for ET-743 treatment
|
|
NZ584695A
(en)
|
2007-10-19 |
2011-06-30 |
Pharma Mar Sa |
Improved antitumoral treatments using PM02734 and an EGFR tyrosine kinase inhibitor (erlotinib)
|
|
WO2009077401A1
(en)
|
2007-12-14 |
2009-06-25 |
Pharma Mar, S.A. |
Antitumoral compounds
|
|
RU2489429C2
(ru)
|
2007-12-20 |
2013-08-10 |
Фарма Мар, С.А. |
Противоопухолевые соединения
|
|
US20100323021A1
(en)
|
2008-01-30 |
2010-12-23 |
Pharma Mar, S.A. |
Antitumoral treatments
|
|
MX2010009697A
(es)
|
2008-03-07 |
2010-09-30 |
Pharm Mar S A |
Tratamientos anticancerigenos mejorados.
|
|
RU2010140890A
(ru)
|
2008-03-07 |
2012-04-20 |
Фарма Мар, С.А. (Es) |
Улучшенные способы противоопухолевого лечения
|
|
AU2009248039B2
(en)
|
2008-05-16 |
2014-07-31 |
Pharma Mar, S.A. |
Multiple myeloma treatments
|
|
RU2010151602A
(ru)
|
2008-05-16 |
2012-06-27 |
Фарма Мар, С.А. (Es) |
Комбинированная терапия с помощью рм00104 и другого противоопухолевого средства
|
|
SI2294072T1
(sl)
|
2008-05-23 |
2017-05-31 |
Wyeth Llc |
Triazinske spojine kot inhibitorji P13-kinaze in MTOR
|
|
MX2011000144A
(es)
|
2008-07-03 |
2011-02-24 |
Pharma Mar Sa |
Compuestos antitumorales.
|
|
KR101667062B1
(ko)
|
2008-07-15 |
2016-10-17 |
제넨테크, 인크. |
안트라시클린 유도체 접합체, 그의 제조 방법 및 항-종양 화합물로서의 그의 용도
|
|
RU2011105801A
(ru)
|
2008-07-17 |
2012-08-27 |
Фарма Мар, С.А. (Es) |
Противораковые соединения
|
|
CA2745377A1
(en)
|
2008-12-19 |
2010-06-24 |
Pharma Mar, S.A. |
Anticancer compounds
|
|
WO2010149688A2
(en)
|
2009-06-24 |
2010-12-29 |
Pharma Mar, S.A. |
Antitumoral compounds
|
|
PL2563803T3
(pl)
|
2010-04-27 |
2016-08-31 |
Pharma Mar Sa |
Przeciwnowotworowe laktony steroidowe nienasycone w pozycji 7(8)
|
|
US9428524B2
(en)
|
2010-05-25 |
2016-08-30 |
Pharma Mar, S.A. |
Synthetic process for the manufacture of ecteinascidin compounds
|
|
EP2786756B1
(en)
|
2010-11-12 |
2020-03-11 |
Pharma Mar, S.A. |
Combination therapy with a topoisomerase inhibitor
|
|
DE102012211024B4
(de)
|
2012-06-27 |
2024-10-24 |
Robert Bosch Gmbh |
Verfahren zum Betreiben eines Fahrzeuges
|
|
JP5922518B2
(ja)
|
2012-07-20 |
2016-05-24 |
浜松ホトニクス株式会社 |
シンチレータパネル及び放射線検出器
|
|
GB201309807D0
(en)
|
2013-05-31 |
2013-07-17 |
Pharma Mar Sau |
Antibody drug conjugates
|
|
MX2019000536A
(es)
|
2016-07-14 |
2019-04-01 |
Pfizer |
Nuevas pirimidinas carboxamidas como inhibidores de enzima vanina-1.
|
|
JOP20190254A1
(ar)
*
|
2017-04-27 |
2019-10-27 |
Pharma Mar Sa |
مركبات مضادة للأورام
|
|
TWI824043B
(zh)
*
|
2018-10-25 |
2023-12-01 |
西班牙商瑪製藥股份有限公司 |
藥物抗體共軛物
|