CY1117889T1 - Πολυμερες γαλακτικου οξεος και διεργασια για την παραγωγη αυτου - Google Patents

Πολυμερες γαλακτικου οξεος και διεργασια για την παραγωγη αυτου

Info

Publication number
CY1117889T1
CY1117889T1 CY20161100791T CY161100791T CY1117889T1 CY 1117889 T1 CY1117889 T1 CY 1117889T1 CY 20161100791 T CY20161100791 T CY 20161100791T CY 161100791 T CY161100791 T CY 161100791T CY 1117889 T1 CY1117889 T1 CY 1117889T1
Authority
CY
Cyprus
Prior art keywords
weight
lactic acid
producing
processing
sustained
Prior art date
Application number
CY20161100791T
Other languages
English (en)
Inventor
Kohei Yamamoto
Takashi Aoki
Tsutomu Tani
Yoshio Hata
Original Assignee
Wako Pure Chemichal Industries, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=18729814&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1117889(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wako Pure Chemichal Industries, Ltd. filed Critical Wako Pure Chemichal Industries, Ltd.
Publication of CY1117889T1 publication Critical patent/CY1117889T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/88—Post-polymerisation treatment
    • C08G63/89—Recovery of the polymer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • C08G63/08—Lactones or lactides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/88—Post-polymerisation treatment
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/91—Polymers modified by chemical after-treatment
    • C08G63/912—Polymers modified by chemical after-treatment derived from hydroxycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Ένα φαρμακευτικό σκεύασμα, π.χ. ένα σκεύασμα μικροκάψουλας παρατεταμένης αποδέσμευσης, που περιλαμβάνει ένα πολυμερές γαλακτικού οξέος με 15.000 έως 50.000 μέσο κατά βάρος μοριακό βάρος, όπου το περιεχόμενο πολυμερών υλικών που δεν έχουν περισσότερο από 5.000 μέσο κατά βάρος μοριακό βάρος μέσα σε αυτό δεν είναι περισσότερο από 5% κατά βάρος. Το σκεύασμα μικροκάψουλας παρατεταμένης αποδέσμευσης που ενκαψυλιώνει μία φυσιολογικώς δραστική ουσία μπορεί να αποτρέψει πλήρως την αρχική υπερβολική αποδέσμευση της φυσιολογικώς δραστικής ουσίας από τις μικροκάψουλες και να διατηρήσει ένα σταθερό ρυθμό αποδέσμευσης επί μία μεγάλη χρονική περίοδο.
CY20161100791T 2000-08-07 2016-08-10 Πολυμερες γαλακτικου οξεος και διεργασια για την παραγωγη αυτου CY1117889T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000238051 2000-08-07
EP01954447A EP1310517B2 (en) 2000-08-07 2001-08-06 Lactic acid polymer and process for producing the same

Publications (1)

Publication Number Publication Date
CY1117889T1 true CY1117889T1 (el) 2017-05-17

Family

ID=18729814

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20161100791T CY1117889T1 (el) 2000-08-07 2016-08-10 Πολυμερες γαλακτικου οξεος και διεργασια για την παραγωγη αυτου

Country Status (15)

Country Link
US (3) US7019106B2 (el)
EP (2) EP1693054B1 (el)
JP (2) JP5046447B2 (el)
KR (1) KR100772950B1 (el)
CN (1) CN1269870C (el)
AT (1) ATE322513T1 (el)
AU (1) AU2001276733A1 (el)
CA (1) CA2419065C (el)
CY (1) CY1117889T1 (el)
DE (1) DE60118575T3 (el)
DK (1) DK1310517T4 (el)
ES (2) ES2577389T3 (el)
HK (1) HK1095526A1 (el)
PT (2) PT1693054T (el)
WO (1) WO2002012369A1 (el)

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EP1666518B1 (en) * 2003-09-08 2018-03-28 Chugai Seiyaku Kabushiki Kaisha Hyaluronic acid modification products and drug carriers using them
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Also Published As

Publication number Publication date
CA2419065C (en) 2009-12-22
KR20030046405A (ko) 2003-06-12
DK1310517T4 (da) 2011-01-17
HK1095526A1 (zh) 2007-05-11
KR100772950B1 (ko) 2007-11-02
EP1693054A3 (en) 2007-07-11
DE60118575T3 (de) 2011-05-19
ES2256276T5 (es) 2011-02-22
ES2577389T3 (es) 2016-07-14
JP5046447B2 (ja) 2012-10-10
DE60118575T2 (de) 2006-08-24
AU2001276733A1 (en) 2002-02-18
US20070259036A1 (en) 2007-11-08
EP1310517B2 (en) 2010-11-17
WO2002012369A9 (fr) 2003-04-24
EP1310517A4 (en) 2005-01-05
EP1310517B1 (en) 2006-04-05
US7019106B2 (en) 2006-03-28
DE60118575D1 (de) 2006-05-18
CN1269870C (zh) 2006-08-16
WO2002012369A1 (fr) 2002-02-14
CN1461321A (zh) 2003-12-10
ATE322513T1 (de) 2006-04-15
EP1693054A2 (en) 2006-08-23
US20060128938A1 (en) 2006-06-15
EP1693054B1 (en) 2016-05-25
DK1310517T3 (da) 2006-07-24
US20030153724A1 (en) 2003-08-14
ES2256276T3 (es) 2006-07-16
PT1693054T (pt) 2016-07-07
CA2419065A1 (en) 2002-02-14
PT1310517E (pt) 2006-05-31
US8092830B2 (en) 2012-01-10
JP5622760B2 (ja) 2014-11-12
JP2012107256A (ja) 2012-06-07
JP2002121272A (ja) 2002-04-23
EP1310517A1 (en) 2003-05-14

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