DE60035421D1 - Chitosanpulver enthaltende feste zubereitungen und verfahren zu deren herstellung - Google Patents

Chitosanpulver enthaltende feste zubereitungen und verfahren zu deren herstellung

Info

Publication number
DE60035421D1
DE60035421D1 DE60035421T DE60035421T DE60035421D1 DE 60035421 D1 DE60035421 D1 DE 60035421D1 DE 60035421 T DE60035421 T DE 60035421T DE 60035421 T DE60035421 T DE 60035421T DE 60035421 D1 DE60035421 D1 DE 60035421D1
Authority
DE
Germany
Prior art keywords
medicament
large intestine
chitosan powder
containing solid
chitosal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60035421T
Other languages
English (en)
Other versions
DE60035421T2 (de
Inventor
Norihito Shimono
Masaaki Mori
Yutaka Higashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Pharma Co Ltd
Original Assignee
Sumitomo Dainippon Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Dainippon Pharma Co Ltd filed Critical Sumitomo Dainippon Pharma Co Ltd
Application granted granted Critical
Publication of DE60035421D1 publication Critical patent/DE60035421D1/de
Publication of DE60035421T2 publication Critical patent/DE60035421T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DE60035421T 1999-08-09 2000-08-07 Chitosanpulver enthaltende feste zubereitungen und verfahren zu deren herstellung Expired - Lifetime DE60035421T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP22477799 1999-08-09
JP22477799 1999-08-09
PCT/JP2000/005279 WO2001010467A1 (fr) 1999-08-09 2000-08-07 Preparations solides contenant de la poudre de chitosane et procede de production associe

Publications (2)

Publication Number Publication Date
DE60035421D1 true DE60035421D1 (de) 2007-08-16
DE60035421T2 DE60035421T2 (de) 2008-03-13

Family

ID=16819059

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60035421T Expired - Lifetime DE60035421T2 (de) 1999-08-09 2000-08-07 Chitosanpulver enthaltende feste zubereitungen und verfahren zu deren herstellung

Country Status (12)

Country Link
US (1) US7604820B1 (de)
EP (1) EP1203590B1 (de)
JP (1) JP4659316B2 (de)
KR (1) KR20020015721A (de)
CN (1) CN1162183C (de)
AT (1) ATE366119T1 (de)
AU (1) AU778049B2 (de)
CA (1) CA2378265C (de)
DE (1) DE60035421T2 (de)
ES (1) ES2288152T3 (de)
HK (1) HK1044286A1 (de)
WO (1) WO2001010467A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10332160A1 (de) * 2003-07-15 2005-02-03 Röhm GmbH & Co. KG Multipartikuläre Arzneiform, enthaltend mucoadhaesiv formulierte Peptid- oder Protein-Wirkstoffe, sowie ein Verfahren zur Herstellung der Arzneiform
WO2005030173A1 (en) * 2003-09-25 2005-04-07 Ranbaxy Laboratories Limited Colon-specific drug delivery using interpolymer complexations
DE102004059792A1 (de) 2004-12-10 2006-06-14 Röhm GmbH & Co. KG Multipartikuläre Arzneiform, enthaltend mucoadhaesiv formulierte Nukleinsäure-Wirkstoffe, sowie ein Verfahren zur Herstellung der Arzneiform
GB0607534D0 (en) * 2006-04-13 2006-05-24 Univ London Pharmacy Colonic drug delivery formulation
JP5386176B2 (ja) * 2006-12-21 2014-01-15 フロイント産業株式会社 キトサン溶液及び該溶液から形成されたキトサンコーティング製剤
JP2009191036A (ja) * 2008-02-15 2009-08-27 Ss Pharmaceut Co Ltd 時限放出製剤
JP5496616B2 (ja) * 2009-11-18 2014-05-21 フロイント産業株式会社 大腸ドラッグデリバリーシステム製剤
EP2371356B1 (de) * 2010-03-12 2012-12-19 Phoeme GmbH Pharmazeutische Mehrfachpartikelformulierung zur Kolonabsorption
JP5087167B2 (ja) * 2010-12-28 2012-11-28 フロイント産業株式会社 ビフィズス菌大腸デリバリーカプセル及びその製造方法
US10799460B2 (en) * 2011-09-07 2020-10-13 Roland SAUR-BROSCH Formulation for the controlled release of one or several substances in the digestive tract of a mammal
EP2765998A1 (de) 2011-10-11 2014-08-20 Ranbaxy Laboratories Limited Gastroretentives dosiersystem und verfahren zu seiner herstellung
JP5102401B1 (ja) 2012-03-30 2012-12-19 森下仁丹株式会社 大腸特異崩壊性カプセル
JP6062802B2 (ja) * 2012-08-23 2017-01-18 日清ファルマ株式会社 キトサン含有組成物及びキトサンコーティング組成物
WO2014097664A1 (ja) * 2012-12-21 2014-06-26 日清ファルマ株式会社 大腸送達カプセル及びその製造方法
CN115192537B (zh) * 2022-07-27 2024-03-26 康普药业股份有限公司 一种甲磺酸萘莫司他组合物及其制备方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5188840A (en) * 1985-09-26 1993-02-23 Chugai Seiyaku Kabushiki Kaisha Slow-release pharmaceutical agent
DE3721574A1 (de) * 1987-06-30 1989-01-12 Kettelhack Riker Pharma Gmbh Arzneimittel in form von pellets mit enzymatisch kontrollierter arzneistoff-freisetzung
US5744166A (en) * 1989-02-25 1998-04-28 Danbiosyst Uk Limited Drug delivery compositions
JPH064531B2 (ja) * 1990-06-04 1994-01-19 アイセロ化学株式会社 大腸崩壊性硬質カプセル
JP2773959B2 (ja) * 1990-07-10 1998-07-09 信越化学工業株式会社 大腸内放出性固形製剤
CA2049524A1 (en) 1990-08-30 1992-03-01 Jakob Silbiger Compositions comprising a hydrophillic polymer and a hydrophillic material different therefrom
JP3181062B2 (ja) 1991-01-31 2001-07-03 帝國製薬株式会社 下部消化管崩壊経口製剤
JP3282832B2 (ja) 1991-02-19 2002-05-20 帝國製薬株式会社 持続性錠剤
JP3122478B2 (ja) 1991-02-19 2001-01-09 帝國製薬株式会社 下部消化管放出型経口製剤
JP3592723B2 (ja) 1991-02-19 2004-11-24 帝國製薬株式会社 非崩壊・持続性カプセル製剤
TW209174B (de) * 1991-04-19 1993-07-11 Takeda Pharm Industry Co Ltd
JP2521229B2 (ja) 1993-06-17 1996-08-07 アイセロ化学株式会社 大腸崩壊性組成物及びその製造法
DE69528583T2 (de) 1994-04-22 2003-07-10 Yamanouchi Pharmaceutical Co., Ltd. Kolon-spezifisches arzneistofffreisetzungssystem
US5840332A (en) * 1996-01-18 1998-11-24 Perio Products Ltd. Gastrointestinal drug delivery system
DK1021171T3 (da) 1997-10-09 2003-08-25 Dexcel Pharma Technologies Ltd Lægemiddelfremførelsessystem til forsinket, fuldstændig frigivelse gastrointestinalt
US6197322B1 (en) * 1997-12-23 2001-03-06 Kimberly-Clark Worldwide, Inc. Antimicrobial structures

Also Published As

Publication number Publication date
AU778049B2 (en) 2004-11-11
HK1044286A1 (en) 2002-10-18
ATE366119T1 (de) 2007-07-15
AU6472300A (en) 2001-03-05
CN1162183C (zh) 2004-08-18
DE60035421T2 (de) 2008-03-13
CN1377281A (zh) 2002-10-30
EP1203590B1 (de) 2007-07-04
CA2378265C (en) 2007-11-20
WO2001010467A1 (fr) 2001-02-15
KR20020015721A (ko) 2002-02-28
CA2378265A1 (en) 2001-02-15
EP1203590A1 (de) 2002-05-08
ES2288152T3 (es) 2008-01-01
JP4659316B2 (ja) 2011-03-30
EP1203590A4 (de) 2005-01-19
US7604820B1 (en) 2009-10-20

Similar Documents

Publication Publication Date Title
DE60035421D1 (de) Chitosanpulver enthaltende feste zubereitungen und verfahren zu deren herstellung
DE69915184D1 (de) Pharmazeutische Formulierung und Dosierform bestehend aus Polysacchariden zur kontrollierten Wirkstoff-Freisetzung im Dickdarm
ATE222487T1 (de) Brausemittel und dessen herstellung
CA2312710A1 (en) Sustained release formulation containing three different types of polymers and tablet formed therefrom
DK0820300T3 (da) Biologisk nedbrydelige nanopartikler med kontrolleret frigivelse indeholdende insulin
DK0754452T3 (da) Farmaceutisk præparat i form af en overtrukket kapsel, der frigives i den nedre del af fordøjelsessystemet
MX9704910A (es) Formula de liberacion controlada (albuterol).
EP0871435A4 (de) Drei verschiedene polymertypen enthaltende formulierung mit verzögerter freigabe
ATE213936T1 (de) Pharmazeutische dosisform mit mehrfacher darmlöslicher polymerbeschichtung zur wirkstoffabgabe im kolon
DK0752245T3 (da) Biokompatible og bionedbrydelige nanopartikler udviklet til absorption og afgivelse af proteinholdige lægemidler
DE69630375D1 (de) Pharmazeutische dosierungsform zur freisetzung im colon
HUP9904174A2 (hu) Bőrön át történő adagoláshoz szánt gyógyszerkészítmények
ATE322513T1 (de) Milchsäurepolymer und verfahren zu dessen herstellung
AU4800999A (en) Preparation capable of releasing drug at target site in intestine
HUT53813A (en) Coating material controlling release of medicaments
IL84167A (en) Oral delivery of bioactive agents to and through the peyer's patch by use of microencapsulation
DE69519685D1 (de) Oral anzuwendende arzneizubereitung mit verzögerter wirkstoffabgabe
CA2156726A1 (en) Bisacodyl Dosage Form
HK1068282A1 (en) Method for the preparation of a pharmaceutical composition comprising 5-aminosalicyclic acid for usein treatment of ulcerative colitis and crohn's di sease
EP1138333A4 (de) Arzneimittel zur oralen verabreichung
EP0425298A3 (en) Sustained-release preparation of basic medical agent hydrochloride
KR100624499B1 (ko) 나노졸을 함유한 의약제제
DE4406139A1 (de) Magnetische Depotarzneimittel für die perorale Applikation mit verbesserter Resorption der Wirkstoffe
TH57760A3 (th) การลำเลียงแบบเอนเทอริกและโคโลนิก โดยใช้แคปซูลชนิด hpmc
BR9612800A (pt) Forma de dosagem farmacêutica para distribuição colÈnica.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition