DE69528583T2 - Kolon-spezifisches arzneistofffreisetzungssystem - Google Patents

Kolon-spezifisches arzneistofffreisetzungssystem

Info

Publication number
DE69528583T2
DE69528583T2 DE69528583T DE69528583T DE69528583T2 DE 69528583 T2 DE69528583 T2 DE 69528583T2 DE 69528583 T DE69528583 T DE 69528583T DE 69528583 T DE69528583 T DE 69528583T DE 69528583 T2 DE69528583 T2 DE 69528583T2
Authority
DE
Germany
Prior art keywords
colon
release system
drug release
drug
specific drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69528583T
Other languages
English (en)
Other versions
DE69528583D1 (de
Inventor
Shunsuke Watanabe
Hitoshi Kawai
Masataka Katsuma
Muneo Fukui
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Inc
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Publication of DE69528583D1 publication Critical patent/DE69528583D1/de
Application granted granted Critical
Publication of DE69528583T2 publication Critical patent/DE69528583T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/282—Organic compounds, e.g. fats
    • A61K9/2826—Sugars or sugar alcohols, e.g. sucrose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
DE69528583T 1994-04-22 1995-04-19 Kolon-spezifisches arzneistofffreisetzungssystem Expired - Lifetime DE69528583T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP8511494 1994-04-22
PCT/JP1995/000766 WO1995028963A1 (fr) 1994-04-22 1995-04-19 Systeme de liberation de medicament specifique au colon

Publications (2)

Publication Number Publication Date
DE69528583D1 DE69528583D1 (de) 2002-11-21
DE69528583T2 true DE69528583T2 (de) 2003-07-10

Family

ID=13849609

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69528583T Expired - Lifetime DE69528583T2 (de) 1994-04-22 1995-04-19 Kolon-spezifisches arzneistofffreisetzungssystem
DE69535432T Expired - Lifetime DE69535432T2 (de) 1994-04-22 1995-04-19 Kolon-spezifisches Arzneistofffreisetzungssystem

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69535432T Expired - Lifetime DE69535432T2 (de) 1994-04-22 1995-04-19 Kolon-spezifisches Arzneistofffreisetzungssystem

Country Status (12)

Country Link
US (2) US6368629B1 (de)
EP (2) EP1252896B1 (de)
JP (1) JP3867171B2 (de)
KR (1) KR100388569B1 (de)
CN (1) CN1072964C (de)
AT (2) ATE357221T1 (de)
AU (1) AU689250B2 (de)
DE (2) DE69528583T2 (de)
ES (2) ES2283503T3 (de)
RU (1) RU2155605C2 (de)
TW (1) TW422701B (de)
WO (1) WO1995028963A1 (de)

Families Citing this family (94)

* Cited by examiner, † Cited by third party
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DE69528583T2 (de) * 1994-04-22 2003-07-10 Yamanouchi Pharma Co Ltd Kolon-spezifisches arzneistofffreisetzungssystem
US5912014A (en) * 1996-03-15 1999-06-15 Unigene Laboratories, Inc. Oral salmon calcitonin pharmaceutical products
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US5948892A (en) * 1996-12-16 1999-09-07 Amgen Inc. Analogs of macrophage stimulating protein
AU5775398A (en) * 1996-12-17 1998-07-15 Poli Industria Chimica S.P.A. Site-specific controlled release dosage formulation for mesalamine
DK0955058T3 (da) * 1997-01-09 2004-08-30 Morinaga Milk Industry Co Ltd Lactoferrintabletter
DE19732903A1 (de) 1997-07-30 1999-02-04 Falk Pharma Gmbh Pellet-Formulierung zur Behandlung des Intestinaltraktes
US6099859A (en) * 1998-03-20 2000-08-08 Andrx Pharmaceuticals, Inc. Controlled release oral tablet having a unitary core
DE69915818T2 (de) * 1998-04-30 2005-01-05 Morinaga Milk Industry Co. Ltd. Zuckerbeschichtete tabletten
WO2000040089A1 (en) * 1999-01-05 2000-07-13 Massachusetts Eye And Ear Infirmary Targeted transscleral controlled release drug delivery to the retina and choroid
US6355270B1 (en) * 1999-01-11 2002-03-12 The Regents Of The University Of California Particles for oral delivery of peptides and proteins
IT1312569B1 (it) * 1999-05-21 2002-04-22 Raffaele Ansovini Uso dell'enzima gssg reduttasi per il trattamento terapeutico e laprofilassi di pazienti infettati da hiv.
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PT1183014E (pt) 1999-06-14 2003-12-31 Cosmo Spa Composicoes farmaceuticas orais de libertacao controlada e de dissimulacao de sabor
US8895064B2 (en) 1999-06-14 2014-11-25 Cosmo Technologies Limited Controlled release and taste masking oral pharmaceutical composition
EP1197228A4 (de) 1999-07-02 2004-03-10 Hisamitsu Pharmaceutical Co Arzneimittel für die behandlung von kolorektalem krebs
DE60035421T2 (de) 1999-08-09 2008-03-13 Dainippon Sumitomo Pharma Co., Ltd. Chitosanpulver enthaltende feste zubereitungen und verfahren zu deren herstellung
JP4524009B2 (ja) * 1999-08-09 2010-08-11 大日本住友製薬株式会社 大腸内放出性カプセル製剤
US7892586B2 (en) 2001-02-22 2011-02-22 Suzanne Jaffe Stillman Water containing soluble fiber
US8178150B2 (en) 2000-02-22 2012-05-15 Suzanne Jaffe Stillman Water containing soluble fiber
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US20050175687A1 (en) * 2001-01-30 2005-08-11 Mcallister Stephen M. Pharmaceutical formulations
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US20030044458A1 (en) * 2001-08-06 2003-03-06 Curtis Wright Oral dosage form comprising a therapeutic agent and an adverse-effect agent
AU2011205217B2 (en) * 2001-08-06 2013-06-13 Euro-Celtique S.A. Oral dosage form comprising a therapeutic agent and an adverse-effect agent
US7196059B2 (en) * 2001-09-07 2007-03-27 Biocon Limited Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
JP2003201256A (ja) * 2001-12-28 2003-07-18 Hisamitsu Pharmaceut Co Inc 大腸送達性経口医薬製剤、大腸癌治療用経口医薬製剤および大腸炎治療用経口医薬製剤
US7923025B2 (en) 2002-01-16 2011-04-12 Astellas Pharma Inc. Pharmaceutical composition for oral use with improved absorption
WO2003092665A2 (en) * 2002-05-02 2003-11-13 Massachusetts Eye And Ear Infirmary Ocular drug delivery systems and use thereof
JP2004075582A (ja) * 2002-08-13 2004-03-11 Takeda Chem Ind Ltd 固形医薬組成物に処方される有効成分以外の成分の安定化方法
DE60330161D1 (de) * 2002-08-29 2009-12-31 Activbiotics Pharma Llc Rifalazil zur behandlung von infektionen mit clostridium difficile
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WO2004073551A2 (en) * 2003-02-18 2004-09-02 Massachusetts Eye And Ear Infirmary Transscleral drug delivery device and related methods
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US20050142191A1 (en) * 2003-06-23 2005-06-30 Neurochem (International) Limited Pharmaceutical formulations of amyloid inhibiting compounds
US20060079578A1 (en) * 2003-06-23 2006-04-13 Julie Laurin Pharmaceutical formulations of amyloid inhibiting compounds
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US7737133B2 (en) 2003-09-03 2010-06-15 Agi Therapeutics Ltd. Formulations and methods of treating inflammatory bowel disease
US7943179B2 (en) * 2003-09-23 2011-05-17 Massachusetts Institute Of Technology pH triggerable polymeric particles
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US20080287400A1 (en) * 2004-05-24 2008-11-20 Richard John Dansereau Low Dosage Forms Of Risedronate Or Its Salts
US20080286359A1 (en) * 2004-05-24 2008-11-20 Richard John Dansereau Low Dosage Forms Of Risedronate Or Its Salts
RU2284832C2 (ru) * 2004-08-30 2006-10-10 Николай Александрович Киселев Антимикробная композиция для перорального введения
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CN103120653B (zh) 2007-04-04 2015-09-30 希格默伊德药业有限公司 一种口服药物组合物
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Also Published As

Publication number Publication date
CN1072964C (zh) 2001-10-17
EP1252896A2 (de) 2002-10-30
EP1252896A3 (de) 2003-10-08
JP3867171B2 (ja) 2007-01-10
AU2266895A (en) 1995-11-16
RU2155605C2 (ru) 2000-09-10
US6506407B2 (en) 2003-01-14
KR100388569B1 (ko) 2003-10-11
US20020044975A1 (en) 2002-04-18
EP0759303B1 (de) 2002-10-16
ES2283503T3 (es) 2007-11-01
TW422701B (en) 2001-02-21
EP0759303A4 (de) 1998-05-06
DE69535432D1 (de) 2007-05-03
ATE226090T1 (de) 2002-11-15
EP0759303A1 (de) 1997-02-26
DE69528583D1 (de) 2002-11-21
ATE357221T1 (de) 2007-04-15
WO1995028963A1 (fr) 1995-11-02
AU689250B2 (en) 1998-03-26
CN1146158A (zh) 1997-03-26
EP1252896B1 (de) 2007-03-21
US6368629B1 (en) 2002-04-09
ES2188657T3 (es) 2003-07-01
DE69535432T2 (de) 2007-12-06

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