CY1112100T1 - ΝΕΑ ΕΝΩΣΗ ΤΡΙΣΥΠΟΚΑΤΕΣΤΗΜΕΝΗΣ 8Η-ΠΥΡΙΔΟ[2,3-d]ΠΥΡΙΜΙΔΙΝ-7-ΟΝΗΣ ΓΙΑ ΤΗ ΘΕΡΑΠΕΥΤΙΚΗ ΑΓΩΓΗ ΑΣΘΕΝΕΙΩΝ, ΟΙ ΟΠΟΙΕΣ ΕΧΟΥΝ ΠΡΟΚΛΗΘΕΙ ΜΕ ΤΗ ΜΕΣΟΛΑΒΗΣΗ CSBP/p38 ΚΙΝΑΣΗΣ - Google Patents

ΝΕΑ ΕΝΩΣΗ ΤΡΙΣΥΠΟΚΑΤΕΣΤΗΜΕΝΗΣ 8Η-ΠΥΡΙΔΟ[2,3-d]ΠΥΡΙΜΙΔΙΝ-7-ΟΝΗΣ ΓΙΑ ΤΗ ΘΕΡΑΠΕΥΤΙΚΗ ΑΓΩΓΗ ΑΣΘΕΝΕΙΩΝ, ΟΙ ΟΠΟΙΕΣ ΕΧΟΥΝ ΠΡΟΚΛΗΘΕΙ ΜΕ ΤΗ ΜΕΣΟΛΑΒΗΣΗ CSBP/p38 ΚΙΝΑΣΗΣ

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Publication number
CY1112100T1
CY1112100T1 CY20111101140T CY111101140T CY1112100T1 CY 1112100 T1 CY1112100 T1 CY 1112100T1 CY 20111101140 T CY20111101140 T CY 20111101140T CY 111101140 T CY111101140 T CY 111101140T CY 1112100 T1 CY1112100 T1 CY 1112100T1
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CY
Cyprus
Prior art keywords
pyrimidin
trispipatically
pyridene
those
therapeutic purpose
Prior art date
Application number
CY20111101140T
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English (en)
Inventor
Jerry L Adams
Jeffrey C Boehm
Ralph Hall
Qi Jin
Jiri Kasparec
Domingos J Silva
John J Taggart
Original Assignee
Glaxosmithkline Llc
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Publication date
Application filed by Glaxosmithkline Llc filed Critical Glaxosmithkline Llc
Publication of CY1112100T1 publication Critical patent/CY1112100T1/el

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    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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Abstract

Νέες ενώσεις υποκατεστημένης 2,4,8-τρισυποκατεστημένης 8Η-πυριδο[2,3-d]πυριμιδιν-7-όνης και συνθέσεις για χρήση στην θεραπευτική αγωγή ως αναστολέων κινάσης CSBP/p38.
CY20111101140T 2000-10-23 2011-11-23 ΝΕΑ ΕΝΩΣΗ ΤΡΙΣΥΠΟΚΑΤΕΣΤΗΜΕΝΗΣ 8Η-ΠΥΡΙΔΟ[2,3-d]ΠΥΡΙΜΙΔΙΝ-7-ΟΝΗΣ ΓΙΑ ΤΗ ΘΕΡΑΠΕΥΤΙΚΗ ΑΓΩΓΗ ΑΣΘΕΝΕΙΩΝ, ΟΙ ΟΠΟΙΕΣ ΕΧΟΥΝ ΠΡΟΚΛΗΘΕΙ ΜΕ ΤΗ ΜΕΣΟΛΑΒΗΣΗ CSBP/p38 ΚΙΝΑΣΗΣ CY1112100T1 (el)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US24246100P 2000-10-23 2000-10-23
US31034901P 2001-08-06 2001-08-06
US32661801P 2001-10-02 2001-10-02
EP01994463A EP1333833B1 (en) 2000-10-23 2001-10-23 Novel trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compound for the treatment of CSBP/p38 kinase mediated diseases

Publications (1)

Publication Number Publication Date
CY1112100T1 true CY1112100T1 (el) 2015-11-04

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ID=27399571

Family Applications (1)

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CY20111101140T CY1112100T1 (el) 2000-10-23 2011-11-23 ΝΕΑ ΕΝΩΣΗ ΤΡΙΣΥΠΟΚΑΤΕΣΤΗΜΕΝΗΣ 8Η-ΠΥΡΙΔΟ[2,3-d]ΠΥΡΙΜΙΔΙΝ-7-ΟΝΗΣ ΓΙΑ ΤΗ ΘΕΡΑΠΕΥΤΙΚΗ ΑΓΩΓΗ ΑΣΘΕΝΕΙΩΝ, ΟΙ ΟΠΟΙΕΣ ΕΧΟΥΝ ΠΡΟΚΛΗΘΕΙ ΜΕ ΤΗ ΜΕΣΟΛΑΒΗΣΗ CSBP/p38 ΚΙΝΑΣΗΣ

Country Status (22)

Country Link
US (8) US7323472B2 (el)
EP (2) EP1333833B1 (el)
JP (3) JP4524072B2 (el)
KR (1) KR100850812B1 (el)
CN (2) CN1847229B (el)
AT (1) ATE521353T1 (el)
AU (1) AU2002246855B2 (el)
BR (1) BR0114829A (el)
CA (1) CA2426654C (el)
CY (1) CY1112100T1 (el)
CZ (1) CZ20031125A3 (el)
DK (1) DK1333833T3 (el)
ES (1) ES2372028T3 (el)
HK (1) HK1059562A1 (el)
HU (1) HU229471B1 (el)
IL (5) IL155367A0 (el)
MX (1) MXPA03003612A (el)
NO (1) NO326830B1 (el)
NZ (1) NZ524806A (el)
PL (1) PL362049A1 (el)
PT (1) PT1333833E (el)
WO (1) WO2002059083A2 (el)

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