CY1111871T1 - Υποκατεστημενα βενζιμιδαζολια και μεθοδοι παρασκευης - Google Patents

Υποκατεστημενα βενζιμιδαζολια και μεθοδοι παρασκευης

Info

Publication number
CY1111871T1
CY1111871T1 CY20111100607T CY111100607T CY1111871T1 CY 1111871 T1 CY1111871 T1 CY 1111871T1 CY 20111100607 T CY20111100607 T CY 20111100607T CY 111100607 T CY111100607 T CY 111100607T CY 1111871 T1 CY1111871 T1 CY 1111871T1
Authority
CY
Cyprus
Prior art keywords
preparation
methods
substituted benzimidazoles
formula
benzimidazoles
Prior art date
Application number
CY20111100607T
Other languages
English (en)
Inventor
Martin Dimitroff
Bridget R Miller
Brady S Stillwell
David A Siesel
Tyson Swiftney
Brian Diaz
Danlin Gu
Dyck Jonathan P Van
David Ryckman
Daniel J Poon
Teresa E Pick
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CY1111871T1 publication Critical patent/CY1111871T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Παρέχεται μέθοδος για παρασκευή νέων υποκατεστημένων ενώσεων βενζιμιδαζολίου που έχουν το συντακτικό τύπο (I) χρήσιμων για θεραπεία διαταραχών που προκαλούνται από κινάση όπου τα R1, R2, R3, R4 a, b, και c ορίζονται εδώ στον συνταντικό τύπο (I).
CY20111100607T 2005-08-30 2011-06-27 Υποκατεστημενα βενζιμιδαζολια και μεθοδοι παρασκευης CY1111871T1 (el)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US71253905P 2005-08-30 2005-08-30
US71310805P 2005-08-30 2005-08-30
US73159105P 2005-10-27 2005-10-27
US77468406P 2006-02-17 2006-02-17
EP06790127A EP1924577B1 (en) 2005-08-30 2006-08-30 Substituted benzimidazoles and methods of preparation

Publications (1)

Publication Number Publication Date
CY1111871T1 true CY1111871T1 (el) 2015-11-04

Family

ID=37434025

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20111100607T CY1111871T1 (el) 2005-08-30 2011-06-27 Υποκατεστημενα βενζιμιδαζολια και μεθοδοι παρασκευης
CY20111101214T CY1112157T1 (el) 2005-08-30 2011-12-06 Υποκαθιστουμενες βενζιμιδαζολες ως αναστολεις κινασης

Family Applications After (1)

Application Number Title Priority Date Filing Date
CY20111101214T CY1112157T1 (el) 2005-08-30 2011-12-06 Υποκαθιστουμενες βενζιμιδαζολες ως αναστολεις κινασης

Country Status (37)

Country Link
US (6) US20070049622A1 (el)
EP (2) EP1926722B1 (el)
JP (4) JP5210867B2 (el)
KR (2) KR20080039965A (el)
AR (2) AR057109A1 (el)
AT (2) ATE526325T1 (el)
AU (2) AU2006287688B2 (el)
BR (2) BRPI0615314A2 (el)
CA (2) CA2619966A1 (el)
CR (1) CR9716A (el)
CU (1) CU23784B7 (el)
CY (2) CY1111871T1 (el)
DE (1) DE602006021036D1 (el)
DK (2) DK1926722T3 (el)
EA (1) EA014230B1 (el)
EC (2) ECSP088210A (el)
ES (1) ES2374451T3 (el)
GE (1) GEP20105004B (el)
GT (1) GT200600394A (el)
HK (2) HK1117519A1 (el)
HN (1) HN2008000317A (el)
HR (2) HRP20110312T1 (el)
IL (2) IL189080A (el)
MA (2) MA29772B1 (el)
MY (2) MY148694A (el)
NI (1) NI200800060A (el)
NO (1) NO20081476L (el)
NZ (2) NZ565450A (el)
PE (2) PE20070427A1 (el)
PL (2) PL1924577T3 (el)
PT (2) PT1924577E (el)
RS (1) RS52099B (el)
SI (2) SI1924577T1 (el)
SM (1) SMAP200800022A (el)
TN (2) TNSN08089A1 (el)
TW (2) TWI387592B (el)
WO (2) WO2007027950A1 (el)

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