NO20044548L - Fremgangsmate for fremstilling av 6-alkaliden-penemderivater - Google Patents

Fremgangsmate for fremstilling av 6-alkaliden-penemderivater

Info

Publication number
NO20044548L
NO20044548L NO20044548A NO20044548A NO20044548L NO 20044548 L NO20044548 L NO 20044548L NO 20044548 A NO20044548 A NO 20044548A NO 20044548 A NO20044548 A NO 20044548A NO 20044548 L NO20044548 L NO 20044548L
Authority
NO
Norway
Prior art keywords
preparation
alkalidene
penem derivatives
penem
derivatives
Prior art date
Application number
NO20044548A
Other languages
English (en)
Inventor
Hiroshi Matsunaga
Takao Abe
Chisato Sato
Ado Mihira
Aranapakam Mudumbai Venkatesan
Tsuyoshi Takasaki
Tarek Suhayl Mansour
Hideki Ushirogochi
Koichi Sato
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of NO20044548L publication Critical patent/NO20044548L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/881—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with a hydrogen atom or an unsubstituted hydrocarbon radical, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Foreliggende oppfinnelse tilveiebringer en fremgangsmåte for fremstilling av forbindelser med formel I, som er anvendelige for behandling av bakterieinfeksjon eller sykdom.
NO20044548A 2002-05-01 2004-10-22 Fremgangsmate for fremstilling av 6-alkaliden-penemderivater NO20044548L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37704802P 2002-05-01 2002-05-01
PCT/US2003/013429 WO2003093277A1 (en) 2002-05-01 2003-04-30 Process for preparing 6-alkylidene penem derivatives

Publications (1)

Publication Number Publication Date
NO20044548L true NO20044548L (no) 2004-11-26

Family

ID=29401435

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20044548A NO20044548L (no) 2002-05-01 2004-10-22 Fremgangsmate for fremstilling av 6-alkaliden-penemderivater

Country Status (23)

Country Link
US (1) US20040053913A1 (no)
EP (1) EP1499620B1 (no)
JP (1) JP2005523937A (no)
KR (1) KR20050007369A (no)
CN (1) CN100516069C (no)
AR (1) AR039476A1 (no)
AT (1) ATE456569T1 (no)
AU (2) AU2003228773A1 (no)
BR (1) BR0309753A (no)
CA (1) CA2483533A1 (no)
CR (1) CR7512A (no)
DE (1) DE60331138D1 (no)
EC (1) ECSP045396A (no)
IL (1) IL164900A0 (no)
MX (1) MXPA04010661A (no)
NO (1) NO20044548L (no)
NZ (1) NZ536183A (no)
RU (1) RU2317297C2 (no)
SG (1) SG165159A1 (no)
TW (1) TW200403248A (no)
UA (1) UA78047C2 (no)
WO (1) WO2003093277A1 (no)
ZA (1) ZA200409687B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR039475A1 (es) * 2002-05-01 2005-02-23 Wyeth Corp 6-alquiliden-penems triciclicos como inhibidores de beta-lactamasa
AR039774A1 (es) * 2002-05-01 2005-03-02 Wyeth Corp 6-alquiliden-penems biciclicos como inhibidores de beta-lactamasas
US20040132708A1 (en) * 2002-05-01 2004-07-08 Wyeth Process for preparing 6-alkylidene penem derivatives
CA2525507A1 (en) * 2003-05-16 2004-12-02 Wyeth Holdings Corporation Process for synthesizing .beta.-lactamase inhibitor intermediates
TW200716104A (en) * 2005-06-01 2007-05-01 Wyeth Corp Tricyclic 6-alkylidene-penems as class-D β -lactamases inhibitors
TW200716102A (en) * 2005-06-01 2007-05-01 Wyeth Corp Bicyclic 6-alkylidene-penems as class-D β -lactamases inhibitors
RU2008102912A (ru) * 2005-07-27 2009-09-10 Вайет (Us) Сочетание ингибиторов бетта-лактазмы бициклического 6-алкилиденпенема с бетта-лактанным антибиотиком: антибиотик широкого спектра
BRPI0613928A2 (pt) * 2005-07-27 2011-02-15 Wyeth Corp método para o tratamento de uma infecção ou doença bacteriana; composição; produto; e uso de cefepima ou de um sal farmaceuticamente aceitável da mesma e um composto de fórmula i ou um sal farmaceuticamente aceitável ou éster hidrolisável in vivo do mesmo
GT200600380A (es) * 2005-08-24 2007-03-29 Proceso para la preparacion de inhibidores de beta-lactamasa
US20090018332A1 (en) * 2007-06-28 2009-01-15 Wyeth Processes For Preparing Bicyclic Oxazine Carboxaldehyde and Beta-Lactamase Inhibitors
US20100063023A1 (en) * 2008-09-10 2010-03-11 Wyeth Bicyclic and Tricyclic Substituted 6-Methylidene Carbapenems as Broad Spectrum Beta-Lactamase Inhibitors
CN102020658B (zh) * 2009-09-11 2012-05-23 中国中化股份有限公司 2-氯-6，8-二氢-5H-咪唑[2，1-c]-[1，4]噁嗪及其制备方法
CN102020615B (zh) * 2009-09-11 2012-08-29 中国中化股份有限公司 一种吗啉酮衍生物及其制备方法
US20110288063A1 (en) * 2010-05-19 2011-11-24 Naeja Pharmaceutical Inc. Novel fused bridged bicyclic heteroaryl substituted 6-alkylidene penems as potent beta-lactamase inhibitors
MX354745B (es) 2012-09-25 2018-03-16 Bayer Cropscience Ag 3-fenilisoxazolin-5-carboxamidas 5-oxi-sustituidas y 3-fenilisoxazolin-5-tioamidas 5-oxi-sustituidas herbicidas y fungicidas.

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4206067A (en) * 1978-10-02 1980-06-03 Chevron Research Company Thermally stabilized erosion-inhibited functional fluids containing perhalometal compounds and an organic base
GB8518416D0 (en) * 1985-07-22 1985-08-29 Beecham Group Plc Compounds
DE3752124T2 (de) * 1986-01-17 1998-03-26 Beecham Group Plc Verfahren zur Herstellung von Penem Derivaten und Zwischenprodukte zu dieser Herstellung
US4891369A (en) * 1986-12-03 1990-01-02 Taiho Pharmaceutical Company, Limited 2β-Substituted-methylpenicillanic acid derivatives, and salts and esters thereof
US4977256A (en) * 1987-12-07 1990-12-11 Lederle (Japan), Ltd. Method of eliminating protective groups
GB8729613D0 (en) * 1987-12-18 1988-02-03 Beecham Group Plc Novel compounds
GB9222700D0 (en) * 1992-10-29 1992-12-09 Smithkline Beecham Plc Chemical compounds
WO1995028935A1 (en) * 1994-04-25 1995-11-02 Smithkline Beecham Plc Pharmaceutical formulations containing a beta-lactamase inhibiting penem in combination with a beta-lactam antibiotic and their use in the treatment of bacterial infections
EP1143952B1 (en) * 1998-10-15 2003-02-26 Sarawak Medichem Pharmaceuticals Inc. Method and composition for treating and preventing tuberculosis
GB9928290D0 (en) * 1999-12-01 2000-01-26 Univ Belfast Process for preparing ambient temperature ionic liquids
AR039774A1 (es) * 2002-05-01 2005-03-02 Wyeth Corp 6-alquiliden-penems biciclicos como inhibidores de beta-lactamasas
US20040132708A1 (en) * 2002-05-01 2004-07-08 Wyeth Process for preparing 6-alkylidene penem derivatives
AR039475A1 (es) * 2002-05-01 2005-02-23 Wyeth Corp 6-alquiliden-penems triciclicos como inhibidores de beta-lactamasa
AR046041A1 (es) * 2003-10-03 2005-11-23 Aventis Pharma Inc Procedimiento para la preparacion de compuestos heterociclicos n-amino sustituidos

Also Published As

Publication number Publication date
ZA200409687B (en) 2009-02-25
AU2003228773A1 (en) 2003-11-17
ECSP045396A (es) 2005-01-03
CR7512A (es) 2005-01-05
DE60331138D1 (de) 2010-03-18
RU2317297C2 (ru) 2008-02-20
JP2005523937A (ja) 2005-08-11
NZ536183A (en) 2006-07-28
ATE456569T1 (de) 2010-02-15
IL164900A0 (en) 2005-12-18
TW200403248A (en) 2004-03-01
UA78047C2 (en) 2007-02-15
AR039476A1 (es) 2005-02-23
EP1499620B1 (en) 2010-01-27
AU2010200930A1 (en) 2010-04-01
KR20050007369A (ko) 2005-01-17
SG165159A1 (en) 2010-10-28
CN100516069C (zh) 2009-07-22
CN1649881A (zh) 2005-08-03
CA2483533A1 (en) 2003-11-13
EP1499620A1 (en) 2005-01-26
US20040053913A1 (en) 2004-03-18
RU2004135088A (ru) 2006-01-20
MXPA04010661A (es) 2005-01-25
WO2003093277A1 (en) 2003-11-13
BR0309753A (pt) 2005-03-08

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