ECSP045396A - Proceso para preparar derivados de 6-alquiliden penem - Google Patents

Proceso para preparar derivados de 6-alquiliden penem

Info

Publication number
ECSP045396A
ECSP045396A EC2004005396A ECSP045396A ECSP045396A EC SP045396 A ECSP045396 A EC SP045396A EC 2004005396 A EC2004005396 A EC 2004005396A EC SP045396 A ECSP045396 A EC SP045396A EC SP045396 A ECSP045396 A EC SP045396A
Authority
EC
Ecuador
Prior art keywords
penem
rent
prepare derivatives
derivatives
prepare
Prior art date
Application number
EC2004005396A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of ECSP045396A publication Critical patent/ECSP045396A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/881—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with a hydrogen atom or an unsubstituted hydrocarbon radical, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

La presente invención provee un proceso para hacer compuestos de Fórmula (I), los cuales son útiles para el tratamiento de la infección bacterial o enfermedad.
EC2004005396A 2002-05-01 2004-10-29 Proceso para preparar derivados de 6-alquiliden penem ECSP045396A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37704802P 2002-05-01 2002-05-01

Publications (1)

Publication Number Publication Date
ECSP045396A true ECSP045396A (es) 2005-01-03

Family

ID=29401435

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2004005396A ECSP045396A (es) 2002-05-01 2004-10-29 Proceso para preparar derivados de 6-alquiliden penem

Country Status (23)

Country Link
US (1) US20040053913A1 (es)
EP (1) EP1499620B1 (es)
JP (1) JP2005523937A (es)
KR (1) KR20050007369A (es)
CN (1) CN100516069C (es)
AR (1) AR039476A1 (es)
AT (1) ATE456569T1 (es)
AU (2) AU2003228773A1 (es)
BR (1) BR0309753A (es)
CA (1) CA2483533A1 (es)
CR (1) CR7512A (es)
DE (1) DE60331138D1 (es)
EC (1) ECSP045396A (es)
IL (1) IL164900A0 (es)
MX (1) MXPA04010661A (es)
NO (1) NO20044548L (es)
NZ (1) NZ536183A (es)
RU (1) RU2317297C2 (es)
SG (1) SG165159A1 (es)
TW (1) TW200403248A (es)
UA (1) UA78047C2 (es)
WO (1) WO2003093277A1 (es)
ZA (1) ZA200409687B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR039774A1 (es) * 2002-05-01 2005-03-02 Wyeth Corp 6-alquiliden-penems biciclicos como inhibidores de beta-lactamasas
US20040132708A1 (en) * 2002-05-01 2004-07-08 Wyeth Process for preparing 6-alkylidene penem derivatives
AR039475A1 (es) * 2002-05-01 2005-02-23 Wyeth Corp 6-alquiliden-penems triciclicos como inhibidores de beta-lactamasa
MXPA05012113A (es) 2003-05-16 2006-02-08 Wyeth Corp Procedimiento para sintetizar intermediarios inhibidores de beta-lactamasa.
TW200716104A (en) * 2005-06-01 2007-05-01 Wyeth Corp Tricyclic 6-alkylidene-penems as class-D β -lactamases inhibitors
TW200716102A (en) * 2005-06-01 2007-05-01 Wyeth Corp Bicyclic 6-alkylidene-penems as class-D β -lactamases inhibitors
CA2615886A1 (en) * 2005-07-27 2007-02-08 Wyeth Bicyclic 6-alkylidene-penem beta-lactamase inhibitors and beta-lactam antibiotic combination: a broad spectrum antibiotic
JP2009502932A (ja) * 2005-07-27 2009-01-29 ワイス 三環式６−アルキリデンペネムβ−ラクタマーゼ阻害剤およびβ−ラクタム抗生物質の組み合わせ：広範なスペクトルの抗生物質
GT200600380A (es) * 2005-08-24 2007-03-29 Proceso para la preparacion de inhibidores de beta-lactamasa
US20090018332A1 (en) * 2007-06-28 2009-01-15 Wyeth Processes For Preparing Bicyclic Oxazine Carboxaldehyde and Beta-Lactamase Inhibitors
US20100063023A1 (en) * 2008-09-10 2010-03-11 Wyeth Bicyclic and Tricyclic Substituted 6-Methylidene Carbapenems as Broad Spectrum Beta-Lactamase Inhibitors
CN102020615B (zh) * 2009-09-11 2012-08-29 中国中化股份有限公司 一种吗啉酮衍生物及其制备方法
CN102020658B (zh) * 2009-09-11 2012-05-23 中国中化股份有限公司 2-氯-6，8-二氢-5H-咪唑[2，1-c]-[1，4]噁嗪及其制备方法
US20110288063A1 (en) * 2010-05-19 2011-11-24 Naeja Pharmaceutical Inc. Novel fused bridged bicyclic heteroaryl substituted 6-alkylidene penems as potent beta-lactamase inhibitors
JP6285937B2 (ja) 2012-09-25 2018-02-28 バイエル・クロップサイエンス・アクチェンゲゼルシャフト 除草性および殺真菌性の５−オキシ置換３−フェニルイソオキサゾリン−５−カルボキサミドおよび５−オキシ置換３−フェニルイソオキサゾリン−５−チオアミド

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4206067A (en) * 1978-10-02 1980-06-03 Chevron Research Company Thermally stabilized erosion-inhibited functional fluids containing perhalometal compounds and an organic base
GB8518416D0 (en) * 1985-07-22 1985-08-29 Beecham Group Plc Compounds
EP0232966B1 (en) * 1986-01-17 1997-10-08 Beecham Group Plc Process for the preparation of penem compounds and intermediates for this preparation
US4891369A (en) * 1986-12-03 1990-01-02 Taiho Pharmaceutical Company, Limited 2β-Substituted-methylpenicillanic acid derivatives, and salts and esters thereof
US4977256A (en) * 1987-12-07 1990-12-11 Lederle (Japan), Ltd. Method of eliminating protective groups
GB8729613D0 (en) * 1987-12-18 1988-02-03 Beecham Group Plc Novel compounds
GB9222700D0 (en) * 1992-10-29 1992-12-09 Smithkline Beecham Plc Chemical compounds
AU690685B2 (en) * 1994-04-25 1998-04-30 Smithkline Beecham Plc Pharmaceutical formulations containing a beta-lactamase inhibiting penem in combination with a beta-lactam antibiotic and their use in the treatment of bacterial infections
CA2346813A1 (en) * 1998-10-15 2000-04-20 Sarawak Medichem Pharmaceuticals Incorporated Method and composition for treating and preventing tuberculosis
GB9928290D0 (en) * 1999-12-01 2000-01-26 Univ Belfast Process for preparing ambient temperature ionic liquids
AR039475A1 (es) * 2002-05-01 2005-02-23 Wyeth Corp 6-alquiliden-penems triciclicos como inhibidores de beta-lactamasa
US20040132708A1 (en) * 2002-05-01 2004-07-08 Wyeth Process for preparing 6-alkylidene penem derivatives
AR039774A1 (es) * 2002-05-01 2005-03-02 Wyeth Corp 6-alquiliden-penems biciclicos como inhibidores de beta-lactamasas
AR046041A1 (es) * 2003-10-03 2005-11-23 Aventis Pharma Inc Procedimiento para la preparacion de compuestos heterociclicos n-amino sustituidos

Also Published As

Publication number Publication date
TW200403248A (en) 2004-03-01
IL164900A0 (en) 2005-12-18
RU2317297C2 (ru) 2008-02-20
MXPA04010661A (es) 2005-01-25
SG165159A1 (en) 2010-10-28
RU2004135088A (ru) 2006-01-20
EP1499620A1 (en) 2005-01-26
AU2010200930A1 (en) 2010-04-01
NO20044548L (no) 2004-11-26
ATE456569T1 (de) 2010-02-15
WO2003093277A1 (en) 2003-11-13
CR7512A (es) 2005-01-05
ZA200409687B (en) 2009-02-25
CN1649881A (zh) 2005-08-03
JP2005523937A (ja) 2005-08-11
CN100516069C (zh) 2009-07-22
UA78047C2 (en) 2007-02-15
BR0309753A (pt) 2005-03-08
AR039476A1 (es) 2005-02-23
DE60331138D1 (de) 2010-03-18
KR20050007369A (ko) 2005-01-17
US20040053913A1 (en) 2004-03-18
CA2483533A1 (en) 2003-11-13
NZ536183A (en) 2006-07-28
AU2003228773A1 (en) 2003-11-17
EP1499620B1 (en) 2010-01-27

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