NO20080394L - N-(arylalkyl)-1H-pyrrolopyridin-2-karboksamidderivater, fremstilling og anvendelse derav - Google Patents
N-(arylalkyl)-1H-pyrrolopyridin-2-karboksamidderivater, fremstilling og anvendelse deravInfo
- Publication number
- NO20080394L NO20080394L NO20080394A NO20080394A NO20080394L NO 20080394 L NO20080394 L NO 20080394L NO 20080394 A NO20080394 A NO 20080394A NO 20080394 A NO20080394 A NO 20080394A NO 20080394 L NO20080394 L NO 20080394L
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- pyrrolopyridine
- arylalkyl
- carboxamide derivatives
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Abstract
Foreliggende oppfinnelse angår forbindelser med generell formel (I): hvor variablene er som definert i kravene. Oppfinnelsen angår også en fremgangsmåte for fremstilling av nevnte forbindelser og deres terapeutiske anvendelse.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0507804A FR2888848B1 (fr) | 2005-07-22 | 2005-07-22 | Derives de n-(arylalkyl)-1h-pyrrrolopyridine-2-carboxamides, leur preparation et leur application en therapeutique |
PCT/FR2006/001767 WO2007010138A2 (fr) | 2005-07-22 | 2006-07-19 | Derives de ν-(arylalkyl)-1h-pyrrolopyridine-2-carboxamides, leur preparation et leur application en therapeutique |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20080394L true NO20080394L (no) | 2008-03-14 |
Family
ID=36039505
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20080394A NO20080394L (no) | 2005-07-22 | 2008-01-21 | N-(arylalkyl)-1H-pyrrolopyridin-2-karboksamidderivater, fremstilling og anvendelse derav |
Country Status (35)
Country | Link |
---|---|
US (2) | US7763636B2 (no) |
EP (1) | EP1912644B1 (no) |
JP (1) | JP4938012B2 (no) |
KR (1) | KR101257969B1 (no) |
CN (1) | CN101247808B (no) |
AR (1) | AR057668A1 (no) |
AT (1) | ATE451923T1 (no) |
AU (1) | AU2006271518B2 (no) |
BR (1) | BRPI0614066A2 (no) |
CA (1) | CA2615676C (no) |
CR (1) | CR9643A (no) |
CY (1) | CY1109891T1 (no) |
DE (1) | DE602006011170D1 (no) |
DK (1) | DK1912644T3 (no) |
EA (1) | EA013747B1 (no) |
EC (1) | ECSP088105A (no) |
ES (1) | ES2338363T3 (no) |
FR (1) | FR2888848B1 (no) |
HR (1) | HRP20100150T1 (no) |
IL (1) | IL188520A (no) |
MA (1) | MA29617B1 (no) |
MX (1) | MX2008001018A (no) |
MY (1) | MY145062A (no) |
NI (1) | NI200800021A (no) |
NO (1) | NO20080394L (no) |
NZ (1) | NZ564870A (no) |
PL (1) | PL1912644T3 (no) |
PT (1) | PT1912644E (no) |
RS (1) | RS51233B (no) |
SI (1) | SI1912644T1 (no) |
TN (1) | TNSN07485A1 (no) |
TW (1) | TWI386407B (no) |
UA (1) | UA93881C2 (no) |
WO (1) | WO2007010138A2 (no) |
ZA (1) | ZA200800439B (no) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2888847B1 (fr) | 2005-07-22 | 2007-08-31 | Sanofi Aventis Sa | Derives de n-(heteriaryl)-1-heteorarylalkyl-1h-indole-2- carboxamides, leur preparation et application en therapeutique |
FR2910473B1 (fr) | 2006-12-26 | 2009-02-13 | Sanofi Aventis Sa | Derives de n-(amino-heteroaryl)-1h-pyrrolopyridine-2- carboxamides, leur preparation et leur application en therapeutique. |
FR2911605B1 (fr) * | 2007-01-19 | 2009-04-17 | Sanofi Aventis Sa | Derives de pyrrolopyridine-2-carbowamides, leur preparation et leur application en therapeutique |
JP5580735B2 (ja) * | 2007-06-12 | 2014-08-27 | ジェネンテック, インコーポレイテッド | N−置換アザインドール類及び使用方法 |
FR2919610B1 (fr) * | 2007-08-02 | 2009-10-16 | Sanofi Aventis Sa | Derives de n-heteroaryl-carboxamides tricycliques,leur preparation et leur application en therapeutique |
FR2926554B1 (fr) | 2008-01-22 | 2010-03-12 | Sanofi Aventis | Derives de carboxamides azabicycliques, leur preparation et leur application en therapeutique |
FR2926555B1 (fr) | 2008-01-22 | 2010-02-19 | Sanofi Aventis | Derives bicycliques de carboxamides azabicycliques, leur preparation et leur application en therapeutique |
FR2926556B1 (fr) * | 2008-01-22 | 2010-02-19 | Sanofi Aventis | Derives de carboxamides n-azabicycliques, leur preparation et leur application en therapeutique |
GB0915892D0 (en) * | 2009-09-10 | 2009-10-14 | Smithkline Beecham Corp | Compounds |
MX2022009572A (es) * | 2020-02-05 | 2022-12-13 | Univ Rockefeller | Composiciones de pirrolo[2,3-b]piridina-3-carboxamida y métodos para mejorar la pérdida de audición. |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH08295667A (ja) * | 1995-04-27 | 1996-11-12 | Takeda Chem Ind Ltd | 複素環化合物、その製造法および剤 |
JP4241970B2 (ja) * | 1998-10-30 | 2009-03-18 | 中外製薬株式会社 | アミド結合を有するインドール誘導体、及びモノ又はジアザインドール誘導体 |
US6436965B1 (en) * | 2000-03-02 | 2002-08-20 | Merck Frosst Canada & Co. | PDE IV inhibiting amides, compositions and methods of treatment |
DE60325025D1 (de) * | 2002-02-15 | 2009-01-15 | Glaxo Group Ltd | Modulatoren des vanilloidrezeptors |
JP2004091480A (ja) * | 2002-07-11 | 2004-03-25 | Takeda Chem Ind Ltd | ピロロピリジン誘導体およびその用途 |
US7582651B2 (en) * | 2002-07-11 | 2009-09-01 | Takeda Pharmaceutical Company Limited | Pyrrolopyridine derivative and use thereof |
US7531558B2 (en) * | 2003-02-14 | 2009-05-12 | Glaxo Group Limited | Carboxamide derivatives |
US7544803B2 (en) * | 2004-01-23 | 2009-06-09 | Amgen Inc. | Vanilloid receptor ligands and their use in treatments |
FR2897061B1 (fr) * | 2006-02-03 | 2010-09-03 | Sanofi Aventis | Derives de n-heteroaryl-carboxamides tricycliques contenant un motif benzimidazole, leur preparation et leur application en therapeutique. |
-
2005
- 2005-07-22 FR FR0507804A patent/FR2888848B1/fr not_active Expired - Fee Related
-
2006
- 2006-07-19 AU AU2006271518A patent/AU2006271518B2/en not_active Ceased
- 2006-07-19 SI SI200630591T patent/SI1912644T1/sl unknown
- 2006-07-19 JP JP2008522019A patent/JP4938012B2/ja not_active Expired - Fee Related
- 2006-07-19 EA EA200800402A patent/EA013747B1/ru not_active IP Right Cessation
- 2006-07-19 WO PCT/FR2006/001767 patent/WO2007010138A2/fr active Application Filing
- 2006-07-19 DK DK06778888.5T patent/DK1912644T3/da active
- 2006-07-19 KR KR1020087001597A patent/KR101257969B1/ko not_active IP Right Cessation
- 2006-07-19 ZA ZA200800439A patent/ZA200800439B/xx unknown
- 2006-07-19 PL PL06778888T patent/PL1912644T3/pl unknown
- 2006-07-19 CA CA2615676A patent/CA2615676C/fr not_active Expired - Fee Related
- 2006-07-19 CN CN200680030739.0A patent/CN101247808B/zh not_active Expired - Fee Related
- 2006-07-19 RS RSP-2010/0116A patent/RS51233B/sr unknown
- 2006-07-19 NZ NZ564870A patent/NZ564870A/en not_active IP Right Cessation
- 2006-07-19 MX MX2008001018A patent/MX2008001018A/es active IP Right Grant
- 2006-07-19 PT PT06778888T patent/PT1912644E/pt unknown
- 2006-07-19 BR BRPI0614066-1A patent/BRPI0614066A2/pt active Search and Examination
- 2006-07-19 ES ES06778888T patent/ES2338363T3/es active Active
- 2006-07-19 EP EP06778888A patent/EP1912644B1/fr active Active
- 2006-07-19 DE DE602006011170T patent/DE602006011170D1/de active Active
- 2006-07-19 UA UAA200802257A patent/UA93881C2/ru unknown
- 2006-07-19 AT AT06778888T patent/ATE451923T1/de active
- 2006-07-20 AR ARP060103112A patent/AR057668A1/es unknown
- 2006-07-20 MY MYPI20063489A patent/MY145062A/en unknown
- 2006-07-21 TW TW095126724A patent/TWI386407B/zh not_active IP Right Cessation
-
2007
- 2007-12-26 TN TNP2007000485A patent/TNSN07485A1/fr unknown
- 2007-12-31 IL IL188520A patent/IL188520A/en not_active IP Right Cessation
-
2008
- 2008-01-07 MA MA30554A patent/MA29617B1/fr unknown
- 2008-01-08 CR CR9643A patent/CR9643A/es unknown
- 2008-01-08 US US11/970,886 patent/US7763636B2/en not_active Expired - Fee Related
- 2008-01-14 EC EC2008008105A patent/ECSP088105A/es unknown
- 2008-01-18 NI NI200800021A patent/NI200800021A/es unknown
- 2008-01-21 NO NO20080394A patent/NO20080394L/no not_active Application Discontinuation
-
2010
- 2010-03-12 CY CY20101100239T patent/CY1109891T1/el unknown
- 2010-03-16 HR HR20100150T patent/HRP20100150T1/hr unknown
- 2010-06-15 US US12/815,593 patent/US20100249183A1/en not_active Abandoned
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