CY1110596T1 - L-ιστιδινη σε οφθαλμικα διαλυματα - Google Patents

L-ιστιδινη σε οφθαλμικα διαλυματα

Info

Publication number
CY1110596T1
CY1110596T1 CY20101100066T CY101100066T CY1110596T1 CY 1110596 T1 CY1110596 T1 CY 1110596T1 CY 20101100066 T CY20101100066 T CY 20101100066T CY 101100066 T CY101100066 T CY 101100066T CY 1110596 T1 CY1110596 T1 CY 1110596T1
Authority
CY
Cyprus
Prior art keywords
eye
weight
testidine
contact lenses
lenses
Prior art date
Application number
CY20101100066T
Other languages
English (en)
Inventor
Francis Xavier Smith
Original Assignee
Fxs Ventures, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fxs Ventures, Llc filed Critical Fxs Ventures, Llc
Publication of CY1110596T1 publication Critical patent/CY1110596T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/327—Peroxy compounds, e.g. hydroperoxides, peroxides, peroxyacids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4172—Imidazole-alkanecarboxylic acids, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/40—Peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A61L12/086—Container, accessories or devices therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A61L12/12—Non-macromolecular oxygen-containing compounds, e.g. hydrogen peroxide or ozone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A61L12/12—Non-macromolecular oxygen-containing compounds, e.g. hydrogen peroxide or ozone
    • A61L12/124—Hydrogen peroxide; Peroxy compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
    • A61L12/141—Biguanides, e.g. chlorhexidine
    • A61L12/142—Polymeric biguanides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame

Abstract

Η εφεύρεση αναφέρεται σε ένα υδατικό οφθαλμικό διάλυμα περιλαμβάνον από 0,01 έως περίπου 1,0% κατά βάρος L-ιστιδίνη· 0,01 έως 0,0001% κατά βάρος υπεροξείδιο του υδρογόνου˙ 0,1 έως 500 μέρη ανά εκατομμύριο ενός κατιονικού πολυμερούς συντηρητικού το οποίο προσφέρει ανώτερη συντηρητική αποτελεσματικότητα ιδιαίτερα κατά των μικροβιακών μυκήτων. Αυτά τα διαλύματα μπορούν να χρησιμοποιηθούν με διάφορους τρόπους περιλαμβανομένου του καθαρισμού των φακών επαφής, της πλύσεως των φακών επαφής ενώ ευρίσκονται στον οφθαλμό, της αποθηκεύσεως των φακών και στη διανομή δραστικών φαρμακευτικών παραγόντων στον οφθαλμό.
CY20101100066T 2000-11-08 2010-01-21 L-ιστιδινη σε οφθαλμικα διαλυματα CY1110596T1 (el)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US24668900P 2000-11-08 2000-11-08
US24670700P 2000-11-08 2000-11-08
US24670900P 2000-11-08 2000-11-08
US24670800P 2000-11-08 2000-11-08
EP01993437A EP1339414B1 (en) 2000-11-08 2001-11-08 L-histidine in ophthalmic solutions

Publications (1)

Publication Number Publication Date
CY1110596T1 true CY1110596T1 (el) 2015-04-29

Family

ID=27500231

Family Applications (3)

Application Number Title Priority Date Filing Date
CY20081101189T CY1108439T1 (el) 2000-11-08 2008-10-23 Βελτιωμενα οφθαλμικα διαλυματα και διαλυματα φακων επαφης με μια πηγη υπεροξειδιου και ενα κατιονικο πολυμερικο συντηρητικο
CY20081101188T CY1108438T1 (el) 2000-11-08 2008-10-23 Βελτιωμενα οφθαλμικα διαλυματα και διαλυματα φακων επαφης που περιεχουν μορφες βιταμινης β
CY20101100066T CY1110596T1 (el) 2000-11-08 2010-01-21 L-ιστιδινη σε οφθαλμικα διαλυματα

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CY20081101189T CY1108439T1 (el) 2000-11-08 2008-10-23 Βελτιωμενα οφθαλμικα διαλυματα και διαλυματα φακων επαφης με μια πηγη υπεροξειδιου και ενα κατιονικο πολυμερικο συντηρητικο
CY20081101188T CY1108438T1 (el) 2000-11-08 2008-10-23 Βελτιωμενα οφθαλμικα διαλυματα και διαλυματα φακων επαφης που περιεχουν μορφες βιταμινης β

Country Status (13)

Country Link
US (1) US20060078626A1 (el)
EP (5) EP3045168A1 (el)
JP (6) JP5258139B2 (el)
CN (3) CN1212848C (el)
AT (3) ATE454157T1 (el)
AU (5) AU2002251685B8 (el)
CA (3) CA2428997A1 (el)
CY (3) CY1108439T1 (el)
DE (3) DE60135478D1 (el)
DK (3) DK1331902T3 (el)
ES (4) ES2337446T3 (el)
PT (3) PT1331902E (el)
WO (3) WO2002038077A2 (el)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030129083A1 (en) * 1997-11-26 2003-07-10 Advanced Medical Optics, Inc. Multi purpose contact lens care compositions including propylene glycol or glycerin
US20060127496A1 (en) * 2000-11-08 2006-06-15 Bioconcept Laboratories L-histidine in ophthalmic solutions
US9492582B2 (en) * 2000-11-08 2016-11-15 Fxs Ventures, Llc Ophthalmic and contact lens solutions containing simple saccharides as preservative enhancers
US20070098813A1 (en) * 2000-11-08 2007-05-03 Fxs Ventures, Llc Ophthalmic and contact lens solutions with a peroxide source and a preservative
US9308264B2 (en) 2000-11-08 2016-04-12 Fxs Ventures, Llc Ophthalmic contact lens solutions containing forms of vitamin B
US20070110782A1 (en) * 2000-11-08 2007-05-17 Fxs Ventures, Llc L-histidine in ophthalmic solutions
US20070104744A1 (en) * 2000-11-08 2007-05-10 Fxs Ventures, Llc Ophthalmic and contact lens solutions containing forms of vitamin b
EP1347787B2 (en) 2001-01-09 2010-09-08 Louis Johan Wagenaar Use of dexpanthenol in contact lens care compositions
US8541472B2 (en) 2001-12-05 2013-09-24 Aseptica, Inc. Antiseptic compositions, methods and systems
JP4634024B2 (ja) * 2003-10-23 2011-02-16 株式会社シード コンタクトレンズ用溶液
US20050214382A1 (en) 2004-03-29 2005-09-29 Erning Xia Zinc preservative composition and method of use
EP2147686A1 (en) * 2004-10-01 2010-01-27 Menicon Co., Ltd. Method for packaging contact lenses
EP2957174A1 (en) * 2005-10-25 2015-12-23 Dow Global Technologies Llc Antimicrobial composition and method
EP1948251B1 (en) 2005-11-16 2012-08-01 Novartis AG Lens care solutions
US20090092574A1 (en) 2006-12-29 2009-04-09 Scott Richard W Ophthalmic And Otic Compositions Of Facially Amphiphilic Polymers And Oligomers And Uses Thereof
TWI478915B (zh) * 2008-10-27 2015-04-01 Cellceutix Corp 宿主防禦之合成模擬物及其用途
KR20120106990A (ko) * 2010-01-07 2012-09-27 폴리메딕스, 인코포레이티드 항-헤파린 화합물
RU2450515C1 (ru) * 2010-12-01 2012-05-20 Федеральное государственное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова Федерального агентства по высокотехнологичной медицинской помощи" Средство для консервации донорской роговицы
RU2013133648A (ru) 2010-12-21 2015-01-27 Басф Се Композиция для электролитического осаждения металлов, содержащая выравнивающий агент
TWI480039B (zh) * 2011-03-10 2015-04-11 Pegavision Corp 一種用於隱形眼鏡之液態組成物
DK2709619T3 (en) 2011-05-16 2018-01-15 Cellceutix Corp RELATIONSHIPS FOR USING THE TREATMENT OF MUCOSITIS
DE102012014581A1 (de) * 2012-07-24 2014-01-30 Azoba Health Care Ag Vitaminzubereitung
JP2015147759A (ja) * 2014-01-08 2015-08-20 日油株式会社 点眼剤
CN105168221A (zh) * 2015-10-14 2015-12-23 康普药业股份有限公司 一种治疗脚气病的药物组合物
TWI634205B (zh) * 2016-06-27 2018-09-01 晶碩光學股份有限公司 用以處理隱形眼鏡之溶液
EP3552601A1 (de) 2018-04-11 2019-10-16 Karl Bodenschatz Pharmazeutische zusammensetzung enthaltend dexpanthenol und polihexanid
CN109381480B (zh) * 2018-11-15 2021-02-09 江苏聚锦生物医疗科技有限责任公司 复配聚六亚甲基双胍消毒液及其制备方法
WO2021248008A1 (en) 2020-06-05 2021-12-09 Innovation Pharmaceuticals Inc. Arylamide compounds for treatment and prevention of viral infections

Family Cites Families (120)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US482689A (en) * 1892-09-13 James mcdermott
US2976576A (en) * 1956-04-24 1961-03-28 Wichterle Otto Process for producing shaped articles from three-dimensional hydrophilic high polymers
US3429576A (en) * 1965-08-28 1969-02-25 Yoshiaki Ikeda Golf club having level indicating means and weight means
US3503393A (en) * 1966-05-19 1970-03-31 Blease Anaesthetic Equip Ltd Patient controlled respiratory apparatus
GB1167285A (en) * 1967-03-15 1969-10-15 Ceskoslovenska Akademie Ved Method of Preserving Hydrophilic Gels
US3689673A (en) * 1970-11-10 1972-09-05 Barnes Hind Pharm Inc The process of soaking and sterilizing hydrophilic soft contact lenses with chlorhexidene
US3755561A (en) * 1971-03-22 1973-08-28 Burton Parsons & Co Inc Bactericidal contact lens solution
FR2199470B1 (el) * 1971-06-21 1977-12-30 Wave Energy Systems
US4022834A (en) * 1972-03-16 1977-05-10 A/S Farmaceutisk Industri Antibacterially active hexamethylene-bis-biguanides
US3888782A (en) * 1972-05-08 1975-06-10 Allergan Pharma Soft contact lens preserving solution
US3876768A (en) * 1972-11-06 1975-04-08 Hydrophilics Int Inc Sterilization of soft, hydrophilic acrylate and methacrylate copolymer materials
US3911107A (en) * 1972-12-18 1975-10-07 Flow Pharma Inc Iodine composition and dissipating solution
US3910296A (en) * 1973-04-20 1975-10-07 Allergan Pharma Method of removing proteinaceous deposits from contact lenses
US3943251A (en) * 1973-06-27 1976-03-09 Medow Norman B Ophthamological use of hydrastis compounds
US4029817A (en) * 1973-09-24 1977-06-14 Allergan Pharmaceuticals Soft contact lens preserving solutions
GB1562899A (en) * 1975-06-17 1980-03-19 Wellcome Found Pharmaceutical compositions containing substituted 9-( -d-arabnofuranosyl)purine-5'-phosphate and salts thereof
US4046706A (en) * 1976-04-06 1977-09-06 Flow Pharmaceuticals, Inc. Contact lens cleaning composition
IT1063325B (it) * 1976-05-19 1985-02-11 Brevitex Ets Exploit Dispositivo di stesura della tramanei telai a crochet
US4136173A (en) * 1977-01-31 1979-01-23 American Home Products Corp. Mixed xanthan gum and locust beam gum therapeutic compositions
US4209817A (en) * 1978-03-15 1980-06-24 Square D Company Circuit breaker having an electronic fault sensing and trip initiating unit
US4394381A (en) * 1979-04-13 1983-07-19 George F. And Irene Sherrill 1978 Trust No. 1 Method for the relief of pain
US4361549A (en) * 1979-04-26 1982-11-30 Ortho Pharmaceutical Corporation Complement-fixing monoclonal antibody to human T cells, and methods of preparing same
JPS599600B2 (ja) * 1980-11-14 1984-03-03 花王株式会社 シヤンプ−組成物
US4361548A (en) * 1980-11-28 1982-11-30 Bausch & Lomb Incorporated Contact lens disinfecting and preserving solution (polymeric)
US4361458A (en) * 1981-02-13 1982-11-30 The Wurlitzer Company Piano soundboard and method of making same
US4354952A (en) * 1981-03-12 1982-10-19 Bausch & Lomb Incorporated Contact lens disinfecting and preserving solution comprising chlorhexidine and salts thereof
US4525346A (en) * 1981-09-28 1985-06-25 Alcon Laboratories, Inc. Aqueous antimicrobial ophthalmic solutions
US4820352A (en) * 1983-01-10 1989-04-11 Bausch & Lomb Incorporated Cleaning and conditioning solutions for contact lenses and methods of use
JPS6038323A (ja) * 1983-08-10 1985-02-27 Sankyo Co Ltd 眼科用消炎剤
US4836986A (en) * 1984-09-28 1989-06-06 Bausch & Lomb Incorporated Disinfecting and preserving systems and methods of use
US4758595A (en) * 1984-12-11 1988-07-19 Bausch & Lomb Incorporated Disinfecting and preserving systems and methods of use
US4748189A (en) * 1985-04-19 1988-05-31 Ciba-Geigy Corporation Ophthalmic solutions and methods for improving the comfort and safety of contact lenses
USRE32672E (en) * 1985-09-09 1988-05-24 Allergan, Inc. Method for simultaneously cleaning and disinfecting contact lenses using a mixture of peroxide and proteolytic enzyme
JPH0672866B2 (ja) * 1986-03-19 1994-09-14 本田技研工業株式会社 酸素濃度検出装置
US4863900A (en) * 1987-01-15 1989-09-05 The Research Foundation Of State University Of New York Method for reducing viral transmission with poly-L-histidine
US4783488A (en) * 1987-01-31 1988-11-08 Bausch & Lomb Incorporated Contact lens wetting solution
US5246708A (en) * 1987-10-28 1993-09-21 Pro-Neuron, Inc. Methods for promoting wound healing with deoxyribonucleosides
US5624958A (en) * 1987-12-31 1997-04-29 Isaacs; Charles E. Disinfecting contact lenses
US5192535A (en) * 1988-02-08 1993-03-09 Insite Vision Incorporated Ophthalmic suspensions
JPH01211595A (ja) * 1988-02-18 1989-08-24 Kikkoman Corp 新規Ｎ−アセチル−β−Ｄ−グルコサミン誘導体、その製法及びＮ−アセチル−β−Ｄ−グルコサミニダーゼ活性測定用試薬への利用
ES2091204T3 (es) * 1988-08-04 1996-11-01 Ciba Geigy Ag Metodo y composiciones para conservar soluciones oftalmicas.
US5607698A (en) * 1988-08-04 1997-03-04 Ciba-Geigy Corporation Method of preserving ophthalmic solution and compositions therefor
US5089261A (en) * 1989-01-23 1992-02-18 Cetus Corporation Preparation of a polymer/interleukin-2 conjugate
US4891423A (en) * 1989-03-20 1990-01-02 Stockel Richard F Polymeric biguanides
US5182258A (en) * 1989-03-20 1993-01-26 Orbon Corporation Systemic delivery of polypeptides through the eye
US5175161A (en) * 1989-04-06 1992-12-29 Sankyo Company, Limited Occular hypotensive agents
JP2893537B2 (ja) * 1989-07-20 1999-05-24 東海電化工業株式会社 ヒスチジン―過酸化水素付加物およびその製造法
US4988710A (en) * 1989-08-25 1991-01-29 Washington University Aryl-cycloalkyl-alkanolamines for treatment of cholinergic neurotoxins
US5078908A (en) * 1989-10-02 1992-01-07 Allergan, Inc. Methods for generating chlorine dioxide and compositions for disinfecting
US5279673A (en) * 1990-01-05 1994-01-18 Allergan, Inc. Methods to disinfect contact lenses
US4997626A (en) * 1990-01-05 1991-03-05 Allergan, Inc. Methods to disinfect contact lenses
US5300296A (en) * 1989-11-06 1994-04-05 Frank J. Holly Antimicrobial agent for opthalmic formulations
GB9002422D0 (en) * 1990-02-03 1990-04-04 Boots Co Plc Anti-microbial compositions
US5174872A (en) * 1990-06-08 1992-12-29 Technicon Instruments Corporation Metal-free buffer for ion selective electrode-based assays
CA2098299C (en) * 1990-12-27 1997-05-20 Mary Mowrey-Mckee Method and composition for disinfecting contact lenses
JPH04226666A (ja) * 1990-12-29 1992-08-17 Tome Sangyo Kk コンタクトレンズの消毒洗浄方法
US5460808A (en) 1991-05-15 1995-10-24 Chanel, Inc. Mascara composition
US5523012A (en) * 1991-07-19 1996-06-04 Ciba-Geigy Corporation Hydrogen peroxide disinfection solutions
NZ243749A (en) * 1991-08-30 1994-11-25 Allergan Inc Composition for neutralising and indicating the absence of peroxide comprising a neutralising compound and vitamin b-12
US5439572A (en) * 1991-12-02 1995-08-08 Isoclear, Inc. Lens protective encasement packet
DE69414836T2 (de) * 1993-01-07 1999-06-17 Polymer Technology Corp Schutzmittel für lösungen für kontaktlinsen
AU6363694A (en) * 1993-03-18 1994-10-11 Polymer Technology Corporation Alcohol-containing abrasive composition for cleaning contact lenses
DE4345199C2 (de) * 1993-05-22 1995-10-12 Asta Medica Ag Verwendung von Dihydroliponsäure zur Unterdrückung von Unverträglichkeitsreaktionen im Grenzbereich von Implantaten mit lebendem Körpergewebe
ES2122288T3 (es) * 1993-05-26 1998-12-16 Fresenius Ag Antiinfeccioso.
US5561107A (en) * 1993-06-04 1996-10-01 Demeter Biotechnologies, Ltd. Method of enhancing wound healing by stimulating fibroblast and keratinocyte growth in vivo, utilizing amphipathic peptides
US5968904A (en) * 1993-06-04 1999-10-19 Demegen, Inc. Modified arginine containing lytic peptides and method of making the same by glyoxylation
IL109762A0 (en) * 1993-06-18 1994-08-26 Allergan Inc Method for treating hypoxia-associated ocular complications
US5661130A (en) * 1993-06-24 1997-08-26 The Uab Research Foundation Absorption enhancers for drug administration
US5449658A (en) * 1993-12-07 1995-09-12 Zeneca, Inc. Biocidal compositions comprising polyhexamethylene biguanide and EDTA, and methods for treating commercial and recreational water
US5591773A (en) * 1994-03-14 1997-01-07 The Trustees Of Columbia University In The City Of New York Inhibition of cataract formation, diseases resulting from oxidative stress, and HIV replication by caffeic acid esters
US5361287A (en) * 1994-03-29 1994-11-01 B&W Fuel Company Nuclear fuel assembly lower end fitting
WO1995026734A1 (en) * 1994-04-04 1995-10-12 Freeman William R Use of phosphonylmethoxyalkyl nucleosides for the treatment of raised intraocular pressure
US5674450A (en) * 1994-04-28 1997-10-07 Johnson & Johnson Medical, Inc. Vapor sterilization using a non-aqueous source of hydrogen peroxide
US5547990A (en) * 1994-05-20 1996-08-20 Lonza, Inc. Disinfectants and sanitizers with reduced eye irritation potential
AU3070395A (en) * 1994-07-22 1996-02-22 Alcon Laboratories, Inc. Use of low molecular weight amino acids in ophthalmic compositions
US5494937A (en) * 1994-07-22 1996-02-27 Alcon Laboratories, Inc. Saline solution for treating contact lenses
US5849291A (en) * 1994-10-17 1998-12-15 Symbollon Corporation Opthalmic non-irritating iodine medicament
DE69535413T2 (de) * 1994-10-20 2007-11-29 Sysmex Corp. Reagenz und Verfahren zur Analyse fester Bestandteile im Harn
JP3968131B2 (ja) * 1994-11-28 2007-08-29 サンスター株式会社 抗菌製剤
JP3442168B2 (ja) * 1994-11-30 2003-09-02 旭化成アイミー株式会社 ケア用品
US6024954A (en) * 1994-12-12 2000-02-15 Allergan Compositions and methods for disinfecting contact lenses and preserving contact lens care products
US5739178A (en) * 1995-05-15 1998-04-14 Allergan Polymer, article and method for inhibiting the growth of ocular pathogens in eye care products
US5611464A (en) * 1995-05-30 1997-03-18 Ciba Geigy Corporation Container for preserving media in the tip of a solution dispenser
US5718895A (en) * 1995-11-16 1998-02-17 Alcon Laboratories, Inc. Enzymes with low isoelectric points for use in contact lens cleaning
US5780450A (en) * 1995-11-21 1998-07-14 Alcon Laboratories, Inc. Use of adenosine uptake inhibitors for treating retinal or optic nerve head damage
US5965736A (en) * 1996-01-16 1999-10-12 Lumigen, Inc. Compositions and methods for generating red chemiluminescence
WO1997026923A1 (en) * 1996-01-22 1997-07-31 Bausch & Lomb Incorporated Dual neutralization system for iodine treatment of contact lenses
AU720405B2 (en) * 1996-02-16 2000-06-01 Regents Of The University Of California, The Antimicrobial peptides and methods of use
EP0888249A4 (en) * 1996-03-18 2000-01-19 Bio Lab Inc COMPOSITIONS FOR WATER PURIFICATION
US6358897B1 (en) * 1996-06-07 2002-03-19 Alcon Laboratories, Inc. Alkyl trypsin compositions and methods of use in contact lens cleaning and disinfecting systems
US5719110A (en) * 1996-08-14 1998-02-17 Allergan Contact lens care compositions with inositol phosphate components
JP3829380B2 (ja) * 1996-12-18 2006-10-04 住友化学株式会社 害虫忌避剤及び害虫忌避方法
US5952320A (en) * 1997-01-07 1999-09-14 Abbott Laboratories Macrocyclic inhibitors of matrix metalloproteinases and TNFα secretion
US5945446A (en) * 1997-02-10 1999-08-31 Laubc Biochemicals, Corporation Process for preparing synthetic soil-extract materials and medicaments based thereon
US6022732A (en) * 1997-04-09 2000-02-08 Allergan Hydrogen peroxide destroying compositions and methods of using same
RU2127100C1 (ru) * 1997-04-17 1999-03-10 Борзенок Сергей Анатольевич Глазные капли "пиротоник"
US5811446A (en) * 1997-04-18 1998-09-22 Cytos Pharmaceuticals Llc Prophylactic and therapeutic methods for ocular degenerative diseases and inflammations and histidine compositions therefor
US5925320A (en) * 1997-06-04 1999-07-20 Jones; John P. Air purification system
JPH11137649A (ja) * 1997-11-10 1999-05-25 Tomey Technology Kk コンタクトレンズの洗浄消毒方法
ID24946A (id) * 1997-11-12 2000-08-31 Bausch & Lomb Perawatan lensa kontak dengan larutan berair yang terdiri dari alkali karbonat
US6056920A (en) * 1997-12-12 2000-05-02 Vertex Pharmaceuticals Incorporated Process for identifying a solvent condition suitable for determining a biophysical property of a protein
JPH11249087A (ja) * 1997-12-18 1999-09-17 Tome:Kk コンタクトレンズ用液剤
JPH11189533A (ja) * 1997-12-25 1999-07-13 Taisho Pharmaceut Co Ltd 点眼薬
JP4065591B2 (ja) * 1998-01-07 2008-03-26 Ｈｏｙａヘルスケア株式会社 コンタクトレンズ用液およびそれを用いたコンタクトレンズの洗浄方法
US6156563A (en) * 1998-01-29 2000-12-05 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Method for clarifying cane sugar juice
JP3883739B2 (ja) * 1998-05-22 2007-02-21 株式会社メニコン コンタクトレンズ用殺菌液
US6117869A (en) * 1998-08-04 2000-09-12 Warner-Lambert Company Compounds for and methods of inhibiting matrix metalloproteinases
US6162393A (en) * 1998-08-06 2000-12-19 Ndt, Inc. Contact lens and ophthalmic solutions
US6432893B1 (en) * 1998-08-21 2002-08-13 Senju Pharmaceutical Co., Ltd. Method for removal of protein from contact lenses
US6309596B1 (en) * 1998-12-15 2001-10-30 Bausch & Lomb Incorporated Treatment of contact lenses with aqueous solution comprising a biguanide disinfectant stabilized by a poloxamine
JP2000347142A (ja) * 1999-06-02 2000-12-15 Tomey Corp コンタクトレンズ用洗浄・保存液剤
US7678836B2 (en) * 1999-11-04 2010-03-16 Fxs Ventures, Llc Method for rendering a contact lens wettable
JP2001302518A (ja) * 2000-02-15 2001-10-31 Rohto Pharmaceut Co Ltd 官能改善方法および官能改善剤
JP2002104971A (ja) * 2000-09-27 2002-04-10 Lion Corp 眼科用組成物
US20040052877A1 (en) * 2000-10-03 2004-03-18 Hisayuki Nakayama Eye drops
US8557868B2 (en) * 2000-11-04 2013-10-15 Fxs Ventures, Llc Ophthalmic and contact lens solutions using low molecular weight amines
MY128762A (en) * 2001-01-12 2007-02-28 Novartis Ag Lens care product containing dexpanthenol
US6550862B2 (en) * 2001-06-14 2003-04-22 Cosco Management, Inc. Juvenile vehicle seat cup holder
US6624203B1 (en) * 2001-11-08 2003-09-23 Francis X. Smith Nucleic acid bases used in ophthalmic solutions
US6617291B1 (en) * 2001-11-08 2003-09-09 Francis X. Smith Ophthalmic and contact lens solutions

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