CS747588A2 - Method of 5-deoxy-5-fluorcytidine's new derivatives production - Google Patents

Method of 5-deoxy-5-fluorcytidine's new derivatives production

Info

Publication number
CS747588A2
CS747588A2 CS887475A CS747588A CS747588A2 CS 747588 A2 CS747588 A2 CS 747588A2 CS 887475 A CS887475 A CS 887475A CS 747588 A CS747588 A CS 747588A CS 747588 A2 CS747588 A2 CS 747588A2
Authority
CS
Czechoslovakia
Prior art keywords
fluorcytidine
deoxy
new derivatives
derivatives production
production
Prior art date
Application number
CS887475A
Other languages
English (en)
Other versions
CS274486B2 (en
Inventor
Morio Fujiu
Hideo Ishitsuka
Masanori Miwa
Isao Umeda
Kazuteru Yokose
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of CS747588A2 publication Critical patent/CS747588A2/cs
Publication of CS274486B2 publication Critical patent/CS274486B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/067—Pyrimidine radicals with ribosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
CS747588A 1987-11-17 1988-11-15 Method of 5-deoxy-5-fluorcytidine's new derivatives production CS274486B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP87116926 1987-11-17

Publications (2)

Publication Number Publication Date
CS747588A2 true CS747588A2 (en) 1990-09-12
CS274486B2 CS274486B2 (en) 1991-04-11

Family

ID=8197450

Family Applications (1)

Application Number Title Priority Date Filing Date
CS747588A CS274486B2 (en) 1987-11-17 1988-11-15 Method of 5-deoxy-5-fluorcytidine's new derivatives production

Country Status (34)

Country Link
US (1) US4966891A (cs)
EP (1) EP0316704B1 (cs)
JP (1) JPH0678350B2 (cs)
KR (1) KR970000241B1 (cs)
CN (1) CN1022688C (cs)
AR (1) AR247217A1 (cs)
AT (1) ATE124951T1 (cs)
AU (1) AU619220B2 (cs)
CA (1) CA1327358C (cs)
CS (1) CS274486B2 (cs)
DE (2) DE10199027I2 (cs)
DK (1) DK170893B1 (cs)
DZ (1) DZ1270A1 (cs)
ES (1) ES2074429T3 (cs)
FI (1) FI89804C (cs)
GR (1) GR3017686T3 (cs)
HU (1) HU199866B (cs)
IE (1) IE883430L (cs)
IL (1) IL88363A0 (cs)
IS (1) IS1895B (cs)
LT (1) LT2185B (cs)
LU (1) LU90769I2 (cs)
LV (1) LV5624A3 (cs)
MC (1) MC1992A1 (cs)
MX (1) MX173347B (cs)
NL (1) NL300045I2 (cs)
NO (2) NO171167C (cs)
NZ (1) NZ226923A (cs)
PH (1) PH25641A (cs)
PT (1) PT89009B (cs)
SU (1) SU1736342A3 (cs)
UA (1) UA19333A (cs)
YU (1) YU47122B (cs)
ZA (1) ZA888428B (cs)

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US3404144A (en) * 1965-12-23 1968-10-01 Research Corp 1-beta-d-arabinofuranosyl-5-fluorocytosine compounds
GB1379410A (en) * 1971-06-08 1975-01-02 Upjohn Co 1-beta-d-arabino-furanosyl-n4-alpha-aminoacylcytosines
JPS52153977A (en) * 1976-06-11 1977-12-21 Daikin Ind Ltd Synthesis of 5-fluorouracil and its derivatives
US4071680A (en) * 1976-12-20 1978-01-31 Hoffmann-La Roche Inc. 5'-Deoxy-5-fluoropyrimidine nucleosides
CH633810A5 (en) * 1978-01-01 1982-12-31 Hoffmann La Roche Novel nucleosides and process for their preparation
FR2528311B1 (fr) * 1982-06-14 1985-06-14 Synthelabo Compositions pharmaceutiques a base de xylosides et lyxosides de bases puriques et pyrimidiques
JPS61112093A (ja) * 1984-11-05 1986-05-30 Wakunaga Seiyaku Kk ヌクレオチド誘導体

Also Published As

Publication number Publication date
IL88363A0 (en) 1989-06-30
SU1736342A3 (ru) 1992-05-23
EP0316704A2 (de) 1989-05-24
NL300045I1 (nl) 2001-08-01
DE10199027I1 (de) 2001-08-02
ES2074429T3 (es) 1995-09-16
NL300045I2 (nl) 2002-01-02
FI885329A0 (fi) 1988-11-17
PT89009B (pt) 1993-02-26
IE883430L (en) 1989-05-17
HK1003114A1 (en) 1998-10-09
ZA888428B (en) 1989-06-28
PH25641A (en) 1991-08-21
DZ1270A1 (fr) 2004-09-13
DK640388D0 (da) 1988-11-16
NO171167C (no) 1993-02-03
DK640388A (da) 1989-05-18
DE3854148D1 (de) 1995-08-17
KR890008162A (ko) 1989-07-10
HUT48267A (en) 1989-05-29
HU199866B (en) 1990-03-28
PT89009A (pt) 1988-12-01
EP0316704B1 (de) 1995-07-12
AU619220B2 (en) 1992-01-23
NO885106D0 (no) 1988-11-16
IS3412A7 (is) 1989-05-18
NO2001013I2 (no) 2006-05-01
FI89804C (fi) 1993-11-25
DE10199027I2 (de) 2002-01-31
FI89804B (fi) 1993-08-13
YU47122B (sh) 1994-12-28
NO885106L (no) 1989-05-18
CA1327358C (en) 1994-03-01
CS274486B2 (en) 1991-04-11
LT2185B (lt) 1993-10-15
IS1895B (is) 2003-10-20
AU2516888A (en) 1989-05-25
CN1022688C (zh) 1993-11-10
NO171167B (no) 1992-10-26
YU209188A (en) 1990-08-31
NZ226923A (en) 1990-10-26
US4966891A (en) 1990-10-30
LV5624A3 (lv) 1994-05-10
MC1992A1 (fr) 1989-11-30
CN1033183A (zh) 1989-05-31
UA19333A (uk) 1997-12-25
DK170893B1 (da) 1996-03-04
ATE124951T1 (de) 1995-07-15
JPH01153696A (ja) 1989-06-15
AR247217A1 (es) 1994-11-30
EP0316704A3 (en) 1990-11-22
JPH0678350B2 (ja) 1994-10-05
MX173347B (es) 1994-01-03
GR3017686T3 (en) 1996-01-31
MX13836A (es) 1993-10-01
KR970000241B1 (ko) 1997-01-08
FI885329L (fi) 1989-05-18
LU90769I2 (fr) 2001-07-02

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IF00 In force as of 2000-06-30 in czech republic
MK4A Patent expired

Effective date: 20081115