CN109651467A - 一种卡培他滨杂质及其制备方法 - Google Patents
一种卡培他滨杂质及其制备方法 Download PDFInfo
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- CN109651467A CN109651467A CN201910033766.2A CN201910033766A CN109651467A CN 109651467 A CN109651467 A CN 109651467A CN 201910033766 A CN201910033766 A CN 201910033766A CN 109651467 A CN109651467 A CN 109651467A
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- impurity
- capecitabine
- preparation
- deoxidation
- capecitabine impurity
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (10)
Priority Applications (1)
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CN201910033766.2A CN109651467A (zh) | 2019-01-15 | 2019-01-15 | 一种卡培他滨杂质及其制备方法 |
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CN201910033766.2A CN109651467A (zh) | 2019-01-15 | 2019-01-15 | 一种卡培他滨杂质及其制备方法 |
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CN109651467A true CN109651467A (zh) | 2019-04-19 |
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CN201910033766.2A Pending CN109651467A (zh) | 2019-01-15 | 2019-01-15 | 一种卡培他滨杂质及其制备方法 |
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Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3309359A (en) * | 1965-10-22 | 1967-03-14 | Hoffmann La Roche | N-mono-acyl-5-fluorocytosine derivatives and process |
CN1033183A (zh) * | 1987-11-17 | 1989-05-31 | 弗·哈夫曼-拉罗切有限公司 | 氟胞嘧啶核苷衍生物 |
CN1095070A (zh) * | 1992-12-18 | 1994-11-16 | 霍夫曼-拉罗奇有限公司 | 制备n4-酰基-5′-脱氧-5-氟胞苷衍生物的新方法 |
JP2016198075A (ja) * | 2015-04-14 | 2016-12-01 | プラズミア バイオテック,エス.エル. | シトシンヌクレオシドアナログの酵素産生 |
-
2019
- 2019-01-15 CN CN201910033766.2A patent/CN109651467A/zh active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3309359A (en) * | 1965-10-22 | 1967-03-14 | Hoffmann La Roche | N-mono-acyl-5-fluorocytosine derivatives and process |
CN1033183A (zh) * | 1987-11-17 | 1989-05-31 | 弗·哈夫曼-拉罗切有限公司 | 氟胞嘧啶核苷衍生物 |
CN1095070A (zh) * | 1992-12-18 | 1994-11-16 | 霍夫曼-拉罗奇有限公司 | 制备n4-酰基-5′-脱氧-5-氟胞苷衍生物的新方法 |
JP2016198075A (ja) * | 2015-04-14 | 2016-12-01 | プラズミア バイオテック,エス.エル. | シトシンヌクレオシドアナログの酵素産生 |
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Legal Events
Date | Code | Title | Description |
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PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
CB02 | Change of applicant information | ||
CB02 | Change of applicant information |
Address after: 250105 No. 849 Dong Jia town, Licheng District, Shandong, Ji'nan Applicant after: QILU TIANHE PHARMACEUTICAL Co.,Ltd. Applicant after: Shandong Anshun Pharmaceutical Co.,Ltd. Address before: 250105 No. 849 Dong Jia town, Licheng District, Shandong, Ji'nan Applicant before: QILU TIANHE PHARMACEUTICAL Co.,Ltd. Applicant before: QILU TIANHE (LAOLING) PHARMACEUTICAL Co.,Ltd. |
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TA01 | Transfer of patent application right | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20200320 Address after: No. 10678, Wenliang Road, Dongjia street, Licheng District, Jinan City, Shandong Province Applicant after: Shandong Anxin Pharmaceutical Co.,Ltd. Address before: 250105 No. 849 Dong Jia town, Licheng District, Shandong, Ji'nan Applicant before: QILU TIANHE PHARMACEUTICAL Co.,Ltd. Applicant before: Shandong Anshun Pharmaceutical Co.,Ltd. |
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RJ01 | Rejection of invention patent application after publication | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190419 |