US5756747A
(en)
*
|
1989-02-27 |
1998-05-26 |
Riker Laboratories, Inc. |
1H-imidazo 4,5-c!quinolin-4-amines
|
ES2094141T3
(es)
*
|
1989-02-27 |
1997-01-16 |
Riker Laboratories Inc |
1h-imidazo(4,5-c)quinolin-4-aminas como antivirales.
|
US4988815A
(en)
*
|
1989-10-26 |
1991-01-29 |
Riker Laboratories, Inc. |
3-Amino or 3-nitro quinoline compounds which are intermediates in preparing 1H-imidazo[4,5-c]quinolines
|
ATE121088T1
(de)
*
|
1990-10-05 |
1995-04-15 |
Minnesota Mining & Mfg |
Verfahren zur herstellung von imidazo(4,5- c>chinolin-4-aminen.
|
US5389640A
(en)
*
|
1991-03-01 |
1995-02-14 |
Minnesota Mining And Manufacturing Company |
1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines
|
US5175296A
(en)
*
|
1991-03-01 |
1992-12-29 |
Minnesota Mining And Manufacturing Company |
Imidazo[4,5-c]quinolin-4-amines and processes for their preparation
|
US5268376A
(en)
*
|
1991-09-04 |
1993-12-07 |
Minnesota Mining And Manufacturing Company |
1-substituted 1H-imidazo[4,5-c]quinolin-4-amines
|
US5266575A
(en)
*
|
1991-11-06 |
1993-11-30 |
Minnesota Mining And Manufacturing Company |
2-ethyl 1H-imidazo[4,5-ciquinolin-4-amines
|
IL105325A
(en)
*
|
1992-04-16 |
1996-11-14 |
Minnesota Mining & Mfg |
Immunogen/vaccine adjuvant composition
|
US6608201B2
(en)
|
1992-08-28 |
2003-08-19 |
3M Innovative Properties Company |
Process for preparing 1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines
|
US5395937A
(en)
*
|
1993-01-29 |
1995-03-07 |
Minnesota Mining And Manufacturing Company |
Process for preparing quinoline amines
|
US5352784A
(en)
*
|
1993-07-15 |
1994-10-04 |
Minnesota Mining And Manufacturing Company |
Fused cycloalkylimidazopyridines
|
EP0708772B1
(en)
*
|
1993-07-15 |
2000-08-23 |
Minnesota Mining And Manufacturing Company |
IMIDAZO [4,5-c]PYRIDIN-4-AMINES
|
US5648516A
(en)
*
|
1994-07-20 |
1997-07-15 |
Minnesota Mining And Manufacturing Company |
Fused cycloalkylimidazopyridines
|
US5644063A
(en)
*
|
1994-09-08 |
1997-07-01 |
Minnesota Mining And Manufacturing Company |
Imidazo[4,5-c]pyridin-4-amine intermediates
|
US5482936A
(en)
*
|
1995-01-12 |
1996-01-09 |
Minnesota Mining And Manufacturing Company |
Imidazo[4,5-C]quinoline amines
|
US5741908A
(en)
|
1996-06-21 |
1998-04-21 |
Minnesota Mining And Manufacturing Company |
Process for reparing imidazoquinolinamines
|
KR100518903B1
(ko)
|
1996-10-25 |
2005-10-06 |
미네소타 마이닝 앤드 매뉴팩춰링 캄파니 |
Th2 매개 질병 및 관련 질병의 치료용 면역 반응 조절 화합물
|
US6069149A
(en)
*
|
1997-01-09 |
2000-05-30 |
Terumo Kabushiki Kaisha |
Amide derivatives and intermediates for the synthesis thereof
|
AU2002300985B2
(en)
*
|
1997-12-11 |
2004-12-02 |
Minnesota Mining And Manufacturing Company |
Imidazonaphthyridines And Their Use In Inducing Cytokine Biosynthesis
|
UA67760C2
(uk)
*
|
1997-12-11 |
2004-07-15 |
Міннесота Майнінг Енд Мануфакчурінг Компані |
Імідазонафтиридин та тетрагідроімідазонафтиридин, фармацевтична композиція, спосіб індукування біосинтезу цитокінів та спосіб лікування вірусної інфекції, проміжні сполуки
|
DK1512685T3
(da)
*
|
1997-12-11 |
2006-11-20 |
Minnesota Mining & Mfg |
Imidazonaphthyridiner og deres anvendelse til induktion af cytokinbiosyntese
|
US6110929A
(en)
|
1998-07-28 |
2000-08-29 |
3M Innovative Properties Company |
Oxazolo, thiazolo and selenazolo [4,5-c]-quinolin-4-amines and analogs thereof
|
US6518280B2
(en)
*
|
1998-12-11 |
2003-02-11 |
3M Innovative Properties Company |
Imidazonaphthyridines
|
US6486168B1
(en)
|
1999-01-08 |
2002-11-26 |
3M Innovative Properties Company |
Formulations and methods for treatment of mucosal associated conditions with an immune response modifier
|
US20020058674A1
(en)
|
1999-01-08 |
2002-05-16 |
Hedenstrom John C. |
Systems and methods for treating a mucosal surface
|
NZ512628A
(en)
|
1999-01-08 |
2004-03-26 |
3M Innovative Properties Co |
Formulations and methods for treatment of mucosal associated conditions with an immune response modifier
|
US6558951B1
(en)
*
|
1999-02-11 |
2003-05-06 |
3M Innovative Properties Company |
Maturation of dendritic cells with immune response modifying compounds
|
US6541485B1
(en)
|
1999-06-10 |
2003-04-01 |
3M Innovative Properties Company |
Urea substituted imidazoquinolines
|
US6331539B1
(en)
|
1999-06-10 |
2001-12-18 |
3M Innovative Properties Company |
Sulfonamide and sulfamide substituted imidazoquinolines
|
US6573273B1
(en)
|
1999-06-10 |
2003-06-03 |
3M Innovative Properties Company |
Urea substituted imidazoquinolines
|
US6451810B1
(en)
|
1999-06-10 |
2002-09-17 |
3M Innovative Properties Company |
Amide substituted imidazoquinolines
|
US6756382B2
(en)
|
1999-06-10 |
2004-06-29 |
3M Innovative Properties Company |
Amide substituted imidazoquinolines
|
US6916925B1
(en)
|
1999-11-05 |
2005-07-12 |
3M Innovative Properties Co. |
Dye labeled imidazoquinoline compounds
|
US6376669B1
(en)
|
1999-11-05 |
2002-04-23 |
3M Innovative Properties Company |
Dye labeled imidazoquinoline compounds
|
JP3436512B2
(ja)
*
|
1999-12-28 |
2003-08-11 |
株式会社デンソー |
アクセル装置
|
US6894060B2
(en)
*
|
2000-03-30 |
2005-05-17 |
3M Innovative Properties Company |
Method for the treatment of dermal lesions caused by envenomation
|
US6677347B2
(en)
|
2000-12-08 |
2004-01-13 |
3M Innovative Properties Company |
Sulfonamido ether substituted imidazoquinolines
|
UA74593C2
(en)
*
|
2000-12-08 |
2006-01-16 |
3M Innovative Properties Co |
Substituted imidazopyridines
|
UA74852C2
(en)
*
|
2000-12-08 |
2006-02-15 |
3M Innovative Properties Co |
Urea-substituted imidazoquinoline ethers
|
US6664264B2
(en)
*
|
2000-12-08 |
2003-12-16 |
3M Innovative Properties Company |
Thioether substituted imidazoquinolines
|
US6545016B1
(en)
|
2000-12-08 |
2003-04-08 |
3M Innovative Properties Company |
Amide substituted imidazopyridines
|
US6664260B2
(en)
|
2000-12-08 |
2003-12-16 |
3M Innovative Properties Company |
Heterocyclic ether substituted imidazoquinolines
|
US6525064B1
(en)
|
2000-12-08 |
2003-02-25 |
3M Innovative Properties Company |
Sulfonamido substituted imidazopyridines
|
CA2598144A1
(en)
*
|
2000-12-08 |
2006-08-31 |
3M Innovative Properties Company |
Compositions and methods for targeted delivery of immune response modifiers
|
WO2002046749A2
(en)
*
|
2000-12-08 |
2002-06-13 |
3M Innovative Properties Company |
Screening method for identifying compounds that selectively induce interferon alpha
|
US6667312B2
(en)
|
2000-12-08 |
2003-12-23 |
3M Innovative Properties Company |
Thioether substituted imidazoquinolines
|
US6677348B2
(en)
*
|
2000-12-08 |
2004-01-13 |
3M Innovative Properties Company |
Aryl ether substituted imidazoquinolines
|
US6660747B2
(en)
|
2000-12-08 |
2003-12-09 |
3M Innovative Properties Company |
Amido ether substituted imidazoquinolines
|
US6664265B2
(en)
|
2000-12-08 |
2003-12-16 |
3M Innovative Properties Company |
Amido ether substituted imidazoquinolines
|
US6660735B2
(en)
|
2000-12-08 |
2003-12-09 |
3M Innovative Properties Company |
Urea substituted imidazoquinoline ethers
|
US6545017B1
(en)
*
|
2000-12-08 |
2003-04-08 |
3M Innovative Properties Company |
Urea substituted imidazopyridines
|
US7226928B2
(en)
*
|
2001-06-15 |
2007-06-05 |
3M Innovative Properties Company |
Methods for the treatment of periodontal disease
|
JP2005501550A
(ja)
*
|
2001-08-30 |
2005-01-20 |
スリーエム イノベイティブ プロパティズ カンパニー |
免疫反応調整剤分子を用いた形質細胞様樹状細胞を成熟させる方法
|
EP1478371A4
(en)
*
|
2001-10-12 |
2007-11-07 |
Univ Iowa Res Found |
METHODS AND PRODUCTS FOR ENHANCING IMMUNE RESPONSES USING IMIDAZOQUINOLINE COMPOUND
|
JP2005513021A
(ja)
*
|
2001-11-16 |
2005-05-12 |
スリーエム イノベイティブ プロパティズ カンパニー |
Irm化合物およびトール様受容体経路に関する方法および組成物
|
MXPA04005023A
(es)
*
|
2001-11-29 |
2004-08-11 |
3M Innovative Properties Co |
Formulaciones farmaceuticas que comprenden un modificador de respuesta inmune.
|
CA2365732A1
(en)
*
|
2001-12-20 |
2003-06-20 |
Ibm Canada Limited-Ibm Canada Limitee |
Testing measurements
|
US6677349B1
(en)
|
2001-12-21 |
2004-01-13 |
3M Innovative Properties Company |
Sulfonamide and sulfamide substituted imidazoquinolines
|
NZ534566A
(en)
*
|
2002-02-22 |
2007-02-23 |
3M Innovative Properties Co |
Method of reducing and treating UVB-induced immunosuppression
|
WO2003080112A2
(en)
*
|
2002-03-19 |
2003-10-02 |
Powdermed Limited |
Imidazoquinolineamines as adjuvants in hiv dna vaccination
|
AU2003216851B2
(en)
*
|
2002-03-19 |
2008-04-17 |
Powderject Research Limited |
Imidazoquinoline adjuvants for vaccines
|
NZ573064A
(en)
*
|
2002-04-04 |
2011-02-25 |
Coley Pharm Gmbh |
Immunostimulatory G,U-containing oligoribonucleotides
|
GB0211649D0
(en)
*
|
2002-05-21 |
2002-07-03 |
Novartis Ag |
Organic compounds
|
US6743920B2
(en)
|
2002-05-29 |
2004-06-01 |
3M Innovative Properties Company |
Process for imidazo[4,5-c]pyridin-4-amines
|
NZ537054A
(en)
*
|
2002-06-07 |
2006-10-27 |
3M Innovative Properties Co |
Ether substituted imidazopyridines
|
EP2269632B1
(en)
|
2002-08-15 |
2014-01-01 |
3M Innovative Properties Co. |
Immunostimulatory compositions and methods of stimulating an immune response
|
JP2006503068A
(ja)
*
|
2002-09-26 |
2006-01-26 |
スリーエム イノベイティブ プロパティズ カンパニー |
1h−イミダゾダイマー
|
WO2004053452A2
(en)
*
|
2002-12-11 |
2004-06-24 |
3M Innovative Properties Company |
Assays relating to toll-like receptor activity
|
WO2004053057A2
(en)
*
|
2002-12-11 |
2004-06-24 |
3M Innovative Properties Company |
Gene expression systems and recombinant cell lines
|
WO2004058759A1
(en)
*
|
2002-12-20 |
2004-07-15 |
3M Innovative Properties Company |
Aryl / hetaryl substituted imidazoquinolines
|
JP2006512391A
(ja)
|
2002-12-30 |
2006-04-13 |
スリーエム イノベイティブ プロパティズ カンパニー |
組み合わせ免疫賦活薬
|
US7375180B2
(en)
*
|
2003-02-13 |
2008-05-20 |
3M Innovative Properties Company |
Methods and compositions related to IRM compounds and Toll-like receptor 8
|
WO2004075865A2
(en)
*
|
2003-02-27 |
2004-09-10 |
3M Innovative Properties Company |
Selective modulation of tlr-mediated biological activity
|
AU2004218349A1
(en)
|
2003-03-04 |
2004-09-16 |
3M Innovative Properties Company |
Prophylactic treatment of UV-induced epidermal neoplasia
|
JP2006519877A
(ja)
*
|
2003-03-07 |
2006-08-31 |
スリーエム イノベイティブ プロパティズ カンパニー |
1−アミノ1h−イミダゾキノリン
|
US7163947B2
(en)
*
|
2003-03-07 |
2007-01-16 |
3M Innovative Properties Company |
1-Amino 1H-imidazoquinolines
|
CA2518445A1
(en)
*
|
2003-03-13 |
2004-09-23 |
3M Innovative Properties Company |
Method of tattoo removal
|
CA2518082C
(en)
*
|
2003-03-13 |
2013-02-12 |
3M Innovative Properties Company |
Methods for diagnosing skin lesions
|
CN100558361C
(zh)
*
|
2003-03-13 |
2009-11-11 |
3M创新有限公司 |
改善皮肤质量的方法
|
US20040192585A1
(en)
|
2003-03-25 |
2004-09-30 |
3M Innovative Properties Company |
Treatment for basal cell carcinoma
|
ES2423800T3
(es)
|
2003-03-28 |
2013-09-24 |
Novartis Vaccines And Diagnostics, Inc. |
Uso de compuestos orgánicos para la inmunopotenciación
|
US20040265351A1
(en)
|
2003-04-10 |
2004-12-30 |
Miller Richard L. |
Methods and compositions for enhancing immune response
|
AU2004244962A1
(en)
*
|
2003-04-10 |
2004-12-16 |
3M Innovative Properties Company |
Delivery of immune response modifier compounds using metal-containing particulate support materials
|
US7731967B2
(en)
|
2003-04-30 |
2010-06-08 |
Novartis Vaccines And Diagnostics, Inc. |
Compositions for inducing immune responses
|
WO2004110992A2
(en)
*
|
2003-06-06 |
2004-12-23 |
3M Innovative Properties Company |
Process for imidazo[4,5-c] pyridin-4-amines
|
WO2004110991A2
(en)
*
|
2003-06-06 |
2004-12-23 |
3M Innovative Properties Company |
PROCESS FOR IMIDAZO[4,5-c]PYRIDIN-4-AMINES
|
AU2004261243A1
(en)
*
|
2003-07-31 |
2005-02-10 |
3M Innovative Properties Company |
Bioactive compositions comprising triazines
|
CA2534313C
(en)
*
|
2003-08-05 |
2013-03-19 |
3M Innovative Properties Company |
Formulations containing an immune response modifier
|
MXPA06001669A
(es)
|
2003-08-12 |
2006-04-28 |
3M Innovative Properties Co |
Compuestos que contienen imidazo-oxima sustituidos.
|
CA2535338C
(en)
*
|
2003-08-14 |
2013-05-28 |
3M Innovative Properties Company |
Substituted 1h-imidazo[4,5-c]pyridin-4-amines,1h-imidazo[4,5-c]quinolin -4-amines and 1h-imidazo[4,5-c]naphthyridin-4-amines as immune response modifiers
|
US8961477B2
(en)
*
|
2003-08-25 |
2015-02-24 |
3M Innovative Properties Company |
Delivery of immune response modifier compounds
|
US20050048072A1
(en)
*
|
2003-08-25 |
2005-03-03 |
3M Innovative Properties Company |
Immunostimulatory combinations and treatments
|
US7897597B2
(en)
|
2003-08-27 |
2011-03-01 |
3M Innovative Properties Company |
Aryloxy and arylalkyleneoxy substituted imidazoquinolines
|
CA2536578A1
(en)
*
|
2003-09-02 |
2005-03-10 |
3M Innovative Properties Company |
Methods related to the treatment of mucosal associated conditions
|
WO2005023190A2
(en)
|
2003-09-05 |
2005-03-17 |
3M Innovative Properties Company |
Treatment for cd5+ b cell lymphoma
|
JP2007505629A
(ja)
*
|
2003-09-17 |
2007-03-15 |
スリーエム イノベイティブ プロパティズ カンパニー |
Tlr遺伝子発現の選択的調節
|
WO2005033049A2
(en)
*
|
2003-10-01 |
2005-04-14 |
Taro Pharmaceuticals U.S.A., Inc. |
METHOD OF PREPARING 4-AMINO-1H-IMIDAZO(4,5-c)QUINOLINES AND ACID ADDITION SALTS THEREOF
|
US8871782B2
(en)
|
2003-10-03 |
2014-10-28 |
3M Innovative Properties Company |
Alkoxy substituted imidazoquinolines
|
CA2540598C
(en)
|
2003-10-03 |
2013-09-24 |
3M Innovative Properties Company |
Pyrazolopyridines and analogs thereof
|
US7544697B2
(en)
*
|
2003-10-03 |
2009-06-09 |
Coley Pharmaceutical Group, Inc. |
Pyrazolopyridines and analogs thereof
|
US20050096259A1
(en)
*
|
2003-10-31 |
2005-05-05 |
3M Innovative Properties Company |
Neutrophil activation by immune response modifier compounds
|
CA2545774A1
(en)
*
|
2003-11-14 |
2005-06-02 |
3M Innovative Properties Company |
Oxime substituted imidazo ring compounds
|
CA2545825A1
(en)
|
2003-11-14 |
2005-06-02 |
3M Innovative Properties Company |
Hydroxylamine substituted imidazo ring compounds
|
ES2308272T3
(es)
*
|
2003-11-21 |
2008-12-01 |
Novartis Ag |
Derivados de 1h-imidazoquinolina como inhibidores de la proteina quinasa.
|
AU2004293078B2
(en)
*
|
2003-11-25 |
2012-01-19 |
3M Innovative Properties Company |
Substituted imidazo ring systems and methods
|
WO2005051324A2
(en)
*
|
2003-11-25 |
2005-06-09 |
3M Innovative Properties Company |
Hydroxylamine and oxime substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines
|
US8940755B2
(en)
*
|
2003-12-02 |
2015-01-27 |
3M Innovative Properties Company |
Therapeutic combinations and methods including IRM compounds
|
US20050226878A1
(en)
*
|
2003-12-02 |
2005-10-13 |
3M Innovative Properties Company |
Therapeutic combinations and methods including IRM compounds
|
AU2004315771A1
(en)
*
|
2003-12-04 |
2005-08-25 |
3M Innovative Properties Company |
Sulfone substituted imidazo ring ethers
|
CA2552101A1
(en)
*
|
2003-12-29 |
2005-07-21 |
3M Innovative Properties Company |
Piperazine, [1,4]diazepane, [1,4]diazocane, and [1,5]diazocane fused imidazo ring compounds
|
EP1701955A1
(en)
|
2003-12-29 |
2006-09-20 |
3M Innovative Properties Company |
Arylalkenyl and arylalkynyl substituted imidazoquinolines
|
CA2551399A1
(en)
*
|
2003-12-30 |
2005-07-21 |
3M Innovative Properties Company |
Imidazoquinolinyl, imidazopyridinyl, and imidazonaphthyridinyl sulfonamides
|
WO2005067500A2
(en)
*
|
2003-12-30 |
2005-07-28 |
3M Innovative Properties Company |
Enhancement of immune responses
|
EP1729768B1
(en)
|
2004-03-15 |
2018-01-10 |
Meda AB |
Immune response modifier formulations and methods
|
EP1730143A2
(en)
|
2004-03-24 |
2006-12-13 |
3M Innovative Properties Company |
Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
|
JP2007532572A
(ja)
*
|
2004-04-09 |
2007-11-15 |
スリーエム イノベイティブ プロパティズ カンパニー |
免疫反応調整剤を送達させるための方法、組成物および調製物
|
CN101426524A
(zh)
*
|
2004-04-28 |
2009-05-06 |
3M创新有限公司 |
用于粘膜接种疫苗的组合物和方法
|
EP1766034B1
(en)
|
2004-05-21 |
2014-03-19 |
Novartis Vaccines and Diagnostics, Inc. |
Alphavirus vectors for influenza virus vaccines
|
US20050267145A1
(en)
*
|
2004-05-28 |
2005-12-01 |
Merrill Bryon A |
Treatment for lung cancer
|
WO2005123079A2
(en)
*
|
2004-06-14 |
2005-12-29 |
3M Innovative Properties Company |
Urea substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
|
WO2005123080A2
(en)
|
2004-06-15 |
2005-12-29 |
3M Innovative Properties Company |
Nitrogen-containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
|
US7915281B2
(en)
|
2004-06-18 |
2011-03-29 |
3M Innovative Properties Company |
Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and method
|
WO2006009826A1
(en)
|
2004-06-18 |
2006-01-26 |
3M Innovative Properties Company |
Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
|
WO2006038923A2
(en)
|
2004-06-18 |
2006-04-13 |
3M Innovative Properties Company |
Aryl substituted imidazonaphthyridines
|
US8541438B2
(en)
|
2004-06-18 |
2013-09-24 |
3M Innovative Properties Company |
Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines
|
US7884207B2
(en)
*
|
2004-06-18 |
2011-02-08 |
3M Innovative Properties Company |
Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines
|
ITMI20041282A1
(it)
*
|
2004-06-24 |
2004-09-24 |
Dipharma Spa |
Procedimento per la preparazione di imiquimod
|
US20110104186A1
(en)
|
2004-06-24 |
2011-05-05 |
Nicholas Valiante |
Small molecule immunopotentiators and assays for their detection
|
EP2277595A3
(en)
|
2004-06-24 |
2011-09-28 |
Novartis Vaccines and Diagnostics, Inc. |
Compounds for immunopotentiation
|
WO2006026470A2
(en)
*
|
2004-08-27 |
2006-03-09 |
3M Innovative Properties Company |
Hiv immunostimulatory compositions
|
CA2578741C
(en)
*
|
2004-09-02 |
2014-01-14 |
3M Innovative Properties Company |
1-alkoxy 1h-imidazo ring systems and methods
|
EP1784180A4
(en)
|
2004-09-02 |
2009-07-22 |
3M Innovative Properties Co |
2-AMINO-1H-IMIDAZO RING SYSTEMS AND METHOD
|
EP1804583A4
(en)
*
|
2004-10-08 |
2009-05-20 |
3M Innovative Properties Co |
ADJUVANT FOR DNA VACCINE
|
US8080560B2
(en)
*
|
2004-12-17 |
2011-12-20 |
3M Innovative Properties Company |
Immune response modifier formulations containing oleic acid and methods
|
US8436176B2
(en)
*
|
2004-12-30 |
2013-05-07 |
Medicis Pharmaceutical Corporation |
Process for preparing 2-methyl-1-(2-methylpropyl)-1H-imidazo[4,5-c][1,5]naphthyridin-4-amine
|
AU2005322898B2
(en)
|
2004-12-30 |
2011-11-24 |
3M Innovative Properties Company |
Chiral fused (1,2)imidazo(4,5-c) ring compounds
|
EP1830876B1
(en)
|
2004-12-30 |
2015-04-08 |
Meda AB |
Use of imiquimod for the treatment of cutaneous metastases derived from a breast cancer tumor
|
JP5313502B2
(ja)
|
2004-12-30 |
2013-10-09 |
スリーエム イノベイティブ プロパティズ カンパニー |
置換キラル縮合[1,2]イミダゾ[4,5−c]環状化合物
|
JP2008526751A
(ja)
*
|
2004-12-30 |
2008-07-24 |
武田薬品工業株式会社 |
1−(2−メチルプロピル)−1h−イミダゾ[4,5−c][1,5]ナフチリジン−4−アミンエタンスルホナート及び1−(2−メチルプロピル)−1h−イミダゾ[4,5−c][1,5]ナフチリジン−4−アミンメタンスルホナート
|
AU2006210392A1
(en)
|
2005-02-04 |
2006-08-10 |
Coley Pharmaceutical Group, Inc. |
Aqueous gel formulations containing immune response modifiers
|
JP2008530252A
(ja)
|
2005-02-09 |
2008-08-07 |
コーリー ファーマシューティカル グループ,インコーポレイテッド |
オキシムおよびヒドロキシルアミンで置換されたチアゾロ[4,5−c]環化合物ならびに方法
|
CA2597324C
(en)
|
2005-02-09 |
2015-06-30 |
Coley Pharmaceutical Group, Inc. |
Alkyloxy substituted thiazoloquinolines and thiazolonaphthyridines
|
JP2008530113A
(ja)
|
2005-02-11 |
2008-08-07 |
コーリー ファーマシューティカル グループ,インコーポレイテッド |
オキシムおよびヒドロキシラミン置換イミダゾ[4,5−c]環化合物および方法
|
EP1845988A2
(en)
|
2005-02-11 |
2007-10-24 |
3M Innovative Properties Company |
Substituted imidazoquinolines and imidazonaphthyridines
|
EP1858919B1
(en)
|
2005-02-18 |
2012-04-04 |
Novartis Vaccines and Diagnostics, Inc. |
Immunogens from uropathogenic escherichia coli
|
EP1858920B1
(en)
|
2005-02-18 |
2016-02-03 |
GlaxoSmithKline Biologicals SA |
Proteins and nucleic acids from meningitis/sepsis-associated escherichia coli
|
AU2006223634A1
(en)
|
2005-02-23 |
2006-09-21 |
Coley Pharmaceutical Group, Inc. |
Hydroxyalkyl substituted imidazoquinolines
|
JP2008538203A
(ja)
|
2005-02-23 |
2008-10-16 |
コーリー ファーマシューティカル グループ,インコーポレイテッド |
インターフェロンの生合成を優先的に誘導する方法
|
JP2008531567A
(ja)
|
2005-02-23 |
2008-08-14 |
コーリー ファーマシューティカル グループ,インコーポレイテッド |
ヒドロキシアルキル置換イミダゾキノリン化合物および方法
|
EP1851220A2
(en)
|
2005-02-23 |
2007-11-07 |
3M Innovative Properties Company |
Hydroxyalkyl substituted imidazonaphthyridines
|
CN101175493A
(zh)
*
|
2005-03-14 |
2008-05-07 |
3M创新有限公司 |
治疗光化性角化病的方法
|
AU2006232377A1
(en)
|
2005-04-01 |
2006-10-12 |
Coley Pharmaceutical Group, Inc. |
Pyrazolopyridine-1,4-diamines and analogs thereof
|
WO2006107851A1
(en)
|
2005-04-01 |
2006-10-12 |
Coley Pharmaceutical Group, Inc. |
1-substituted pyrazolo (3,4-c) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases
|
JP2008539252A
(ja)
*
|
2005-04-25 |
2008-11-13 |
スリーエム イノベイティブ プロパティズ カンパニー |
免疫活性化組成物
|
GB0510390D0
(en)
*
|
2005-05-20 |
2005-06-29 |
Novartis Ag |
Organic compounds
|
WO2007011777A2
(en)
|
2005-07-18 |
2007-01-25 |
Novartis Ag |
Small animal model for hcv replication
|
ES2577514T3
(es)
*
|
2005-08-22 |
2016-07-15 |
The Regents Of The University Of California |
Antagonistas de TLR
|
ZA200803029B
(en)
*
|
2005-09-09 |
2009-02-25 |
Coley Pharm Group Inc |
Amide and carbamate derivatives of alkyl substituted /V-[4-(4-amino-1H-imidazo[4,5-c] quinolin-1-yl)butyl] methane-sulfonamides and methods
|
US8476292B2
(en)
|
2005-09-09 |
2013-07-02 |
3M Innovative Properties Company |
Amide and carbamate derivatives of N-{2-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c] quinolin-1-Yl]-1,1-dimethylethyl}methanesulfonamide and methods
|
US8889154B2
(en)
|
2005-09-15 |
2014-11-18 |
Medicis Pharmaceutical Corporation |
Packaging for 1-(2-methylpropyl)-1H-imidazo[4,5-c] quinolin-4-amine-containing formulation
|
US7629027B2
(en)
*
|
2005-10-14 |
2009-12-08 |
3M Innovative Properties Company |
Method for making chromonic nanoparticles
|
US7718716B2
(en)
*
|
2005-10-14 |
2010-05-18 |
3M Innovative Properties Company |
Chromonic nanoparticles containing bioactive compounds
|
WO2007047749A1
(en)
|
2005-10-18 |
2007-04-26 |
Novartis Vaccines And Diagnostics Inc. |
Mucosal and systemic immunizations with alphavirus replicon particles
|
US20070100146A1
(en)
*
|
2005-11-03 |
2007-05-03 |
Trevor Dzwiniel |
Process for the preparation of imidazo[4,5-c]-quinolin-4-amines
|
NZ592713A
(en)
|
2005-11-04 |
2012-12-21 |
Novartis Vaccines & Diagnostic |
Adjuvanted influenza vaccines including a cytokine-inducing agents other than an agonist of Toll-Like Receptor 9
|
EP2368572B1
(en)
|
2005-11-04 |
2020-03-04 |
Seqirus UK Limited |
Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture
|
EP1948173B1
(en)
|
2005-11-04 |
2013-07-17 |
3M Innovative Properties Company |
Hydroxy and alkoxy substituted 1h-imidazoquinolines and methods
|
JP2009514850A
(ja)
|
2005-11-04 |
2009-04-09 |
ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル |
アジュバントとして減少した量の水中油型エマルションを有するインフルエンザワクチン
|
NZ568211A
(en)
|
2005-11-04 |
2011-11-25 |
Novartis Vaccines & Diagnostic |
Influenza vaccines including combinations of particulate adjuvants and immunopotentiators
|
WO2007081447A2
(en)
|
2005-11-22 |
2007-07-19 |
Novartis Vaccines And Diagnostics, Inc. |
Norovirus and sapovirus antigens
|
US20070128291A1
(en)
*
|
2005-12-07 |
2007-06-07 |
Tokie Jeffrey H |
Method and Apparatus for Forming Chromonic Nanoparticles
|
US7807661B2
(en)
*
|
2005-12-08 |
2010-10-05 |
3M Innovative Properties Company |
Silver ion releasing articles and methods of manufacture
|
US7323568B2
(en)
*
|
2005-12-12 |
2008-01-29 |
Chemagis Ltd. |
Process for preparing Imiquimod
|
JO2660B1
(en)
|
2006-01-20 |
2012-06-17 |
نوفارتيس ايه جي |
Pi-3 inhibitors and methods of use
|
KR20110110853A
(ko)
|
2006-01-27 |
2011-10-07 |
노파르티스 파르마 아게 |
적혈구응집소 및 기질 단백질을 함유한 인플루엔자 백신
|
PE20070978A1
(es)
*
|
2006-02-14 |
2007-11-15 |
Novartis Ag |
COMPUESTOS HETEROCICLICOS COMO INHIBIDORES DE FOSFATIDILINOSITOL 3-QUINASAS (PI3Ks)
|
US8951528B2
(en)
*
|
2006-02-22 |
2015-02-10 |
3M Innovative Properties Company |
Immune response modifier conjugates
|
WO2007106854A2
(en)
|
2006-03-15 |
2007-09-20 |
Coley Pharmaceutical Group, Inc. |
Hydroxy and alkoxy substituted 1h-imidazonaphthyridines and methods
|
ES2388556T3
(es)
*
|
2006-03-23 |
2012-10-16 |
Novartis Ag |
Compuestos inmunopotenciadores
|
US20100010217A1
(en)
*
|
2006-03-23 |
2010-01-14 |
Valiante Nicholas M |
Methods for the preparation of imidazole-containing compounds
|
EP2357184B1
(en)
|
2006-03-23 |
2015-02-25 |
Novartis AG |
Imidazoquinoxaline compounds as immunomodulators
|
US20100068223A1
(en)
|
2006-03-24 |
2010-03-18 |
Hanno Scheffczik |
Storage of Influenza Vaccines Without Refrigeration
|
CA2647942A1
(en)
|
2006-03-31 |
2007-11-08 |
Novartis Ag |
Combined mucosal and parenteral immunization against hiv
|
TW200808739A
(en)
*
|
2006-04-06 |
2008-02-16 |
Novartis Vaccines & Diagnostic |
Quinazolines for PDK1 inhibition
|
US20070275185A1
(en)
*
|
2006-05-23 |
2007-11-29 |
3M Innovative Properties Company |
Method of making ordered nanostructured layers
|
CA2653941C
(en)
|
2006-05-31 |
2013-01-08 |
The Regents Of The University Of California |
Substituted amino purine derivatives and uses thereof
|
EP2054431B1
(en)
|
2006-06-09 |
2011-08-31 |
Novartis AG |
Conformers of bacterial adhesins
|
US20100129403A1
(en)
|
2006-06-20 |
2010-05-27 |
Transgene S.A. |
Recombinant viral vaccine
|
US7906506B2
(en)
|
2006-07-12 |
2011-03-15 |
3M Innovative Properties Company |
Substituted chiral fused [1,2] imidazo [4,5-c] ring compounds and methods
|
GB0614460D0
(en)
|
2006-07-20 |
2006-08-30 |
Novartis Ag |
Vaccines
|
EP2586790A3
(en)
|
2006-08-16 |
2013-08-14 |
Novartis AG |
Immunogens from uropathogenic Escherichia coli
|
WO2008030511A2
(en)
|
2006-09-06 |
2008-03-13 |
Coley Pharmaceuticial Group, Inc. |
Substituted 3,4,6,7-tetrahydro-5h, 1,2a,4a,8-tetraazacyclopenta[cd]phenalenes
|
CA3016948A1
(en)
|
2006-09-11 |
2008-03-20 |
Seqirus UK Limited |
Making influenza virus vaccines without using eggs
|
CN106045993A
(zh)
*
|
2006-11-20 |
2016-10-26 |
诺华股份有限公司 |
化合物的盐和晶型
|
PL2121011T3
(pl)
|
2006-12-06 |
2014-10-31 |
Novartis Ag |
Szczepionki zawierające antygeny czterech szczepów wirusa grypy
|
US20080149123A1
(en)
*
|
2006-12-22 |
2008-06-26 |
Mckay William D |
Particulate material dispensing hairbrush with combination bristles
|
GB0700562D0
(en)
|
2007-01-11 |
2007-02-21 |
Novartis Vaccines & Diagnostic |
Modified Saccharides
|
US7943771B2
(en)
*
|
2007-01-24 |
2011-05-17 |
Chemagis Ltd. |
Imiquimod production process
|
SI2510946T1
(sl)
|
2007-02-07 |
2015-12-31 |
The Regents Of The University Of California |
Konjugati sintetičnih agonistov TLR in njihove uporabe
|
US7659398B2
(en)
*
|
2007-02-14 |
2010-02-09 |
Chemagis Ltd. |
Imiquimod production process
|
EA201070066A1
(ru)
|
2007-06-27 |
2010-06-30 |
Новартис Аг |
Вакцины против гриппа с низким содержанием добавок
|
GB0714963D0
(en)
|
2007-08-01 |
2007-09-12 |
Novartis Ag |
Compositions comprising antigens
|
AU2008299376B2
(en)
|
2007-09-12 |
2013-02-28 |
Glaxosmithkline Biologicals S.A. |
GAS57 mutant antigens and GAS57 antibodies
|
GB0810305D0
(en)
|
2008-06-05 |
2008-07-09 |
Novartis Ag |
Influenza vaccination
|
GB0818453D0
(en)
|
2008-10-08 |
2008-11-12 |
Novartis Ag |
Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom
|
AU2008340053A1
(en)
|
2007-12-20 |
2009-07-02 |
Novartis Ag |
Thiazole derivatives used as PI 3 kinase inhibitors
|
BRPI0821240B8
(pt)
|
2007-12-21 |
2022-10-04 |
Novartis Ag |
formas mutantes de estreptolisina o
|
EA201001264A1
(ru)
*
|
2008-02-07 |
2011-04-29 |
Дзе Регентс Оф Дзе Юниверсити Оф Калифорния |
Способ лечения заболеваний мочевого пузыря с помощью активатора tlr7
|
EP2268309B1
(en)
|
2008-03-18 |
2015-01-21 |
Novartis AG |
Improvements in preparation of influenza virus vaccine antigens
|
US20100160368A1
(en)
*
|
2008-08-18 |
2010-06-24 |
Gregory Jefferson J |
Methods of Treating Dermatological Disorders and Inducing Interferon Biosynthesis With Shorter Durations of Imiquimod Therapy
|
AU2010204139A1
(en)
|
2009-01-12 |
2011-08-11 |
Novartis Ag |
Cna_B domain antigens in vaccines against gram positive bacteria
|
WO2010088924A1
(en)
|
2009-02-06 |
2010-08-12 |
Telormedix Sa |
Pharmaceutical compositions comprising imidazoquinolin(amines) and derivatives thereof suitable for local administration
|
MX2011008500A
(es)
*
|
2009-02-11 |
2011-09-26 |
Univ California |
Moduladores del receptor tipo toll y tratamiento de enfermedades.
|
JP2012519482A
(ja)
|
2009-03-06 |
2012-08-30 |
ノバルティス アーゲー |
クラミジア抗原
|
CN103800906B
(zh)
|
2009-03-25 |
2017-09-22 |
德克萨斯大学系统董事会 |
用于刺激哺乳动物对病原体的先天免疫抵抗力的组合物
|
US8679505B2
(en)
|
2009-04-14 |
2014-03-25 |
Novartis Ag |
Compositions for immunising against Staphylococcus aureus
|
DE102010018462A1
(de)
|
2009-04-27 |
2011-04-07 |
Novartis Ag |
Impfstoffe zum Schutz gegen Influenza
|
US8629151B2
(en)
|
2009-05-27 |
2014-01-14 |
Selecta Biosciences, Inc. |
Immunomodulatory agent-polymeric compounds
|
US8293753B2
(en)
|
2009-07-02 |
2012-10-23 |
Novartis Ag |
Substituted 2-carboxamide cycloamino ureas
|
AU2010274097B2
(en)
|
2009-07-13 |
2016-06-16 |
Medicis Pharmaceutical Corporation |
Lower dosage strength imiquimod formulations and short dosing regimens for treating genital and perianal warts
|
ES2918381T3
(es)
|
2009-07-15 |
2022-07-15 |
Glaxosmithkline Biologicals Sa |
Composiciones de proteína F de VRS y métodos para producir las mismas
|
JP2012532626A
(ja)
|
2009-07-16 |
2012-12-20 |
ノバルティス アーゲー |
無毒化されたEscherichiacoli免疫原
|
US20110033515A1
(en)
*
|
2009-08-04 |
2011-02-10 |
Rst Implanted Cell Technology |
Tissue contacting material
|
GB0918392D0
(en)
|
2009-10-20 |
2009-12-02 |
Novartis Ag |
Diagnostic and therapeutic methods
|
GB0919690D0
(en)
|
2009-11-10 |
2009-12-23 |
Guy S And St Thomas S Nhs Foun |
compositions for immunising against staphylococcus aureus
|
US9597326B2
(en)
|
2010-04-13 |
2017-03-21 |
Glaxosmithkline Biologicals Sa |
Benzonapthyridine compositions and uses thereof
|
EP2575773A4
(en)
|
2010-05-26 |
2014-06-25 |
Selecta Biosciences Inc |
SYNTHETIC NANOTRÄGERKOMBINATIONSIMPFSTOFFE
|
WO2011149564A1
(en)
|
2010-05-28 |
2011-12-01 |
Tetris Online, Inc. |
Interactive hybrid asynchronous computer game infrastructure
|
GB201009861D0
(en)
|
2010-06-11 |
2010-07-21 |
Novartis Ag |
OMV vaccines
|
US9192661B2
(en)
|
2010-07-06 |
2015-11-24 |
Novartis Ag |
Delivery of self-replicating RNA using biodegradable polymer particles
|
AR082418A1
(es)
|
2010-08-02 |
2012-12-05 |
Novartis Ag |
Formas cristalinas de 1-(4-metil-5-[2-(2,2,2-trifluoro-1,1-dimetil-etil)-piridin-4-il]-tiazol-2-il)-amida de 2-amida del acido (s)-pirrolidin-1,2-dicarboxilico
|
EP3222621B1
(en)
|
2010-08-17 |
2023-03-08 |
3M Innovative Properties Company |
Lipidated immune response modifier compound and its medical use
|
PT2667892T
(pt)
|
2011-01-26 |
2019-06-07 |
Glaxosmithkline Biologicals Sa |
Regime de imunização contra o vsr
|
AU2012213080B2
(en)
|
2011-01-31 |
2014-03-27 |
Novartis Ag |
Novel heterocyclic derivatives
|
JP2014519819A
(ja)
|
2011-05-13 |
2014-08-21 |
ノバルティス アーゲー |
融合前rsvf抗原
|
JP6415979B2
(ja)
|
2011-06-03 |
2018-10-31 |
スリーエム イノベイティブ プロパティズ カンパニー |
ヒドラジノ1h−イミダゾキノリン−4−アミン及びこれから調製された複合体
|
MX347240B
(es)
|
2011-06-03 |
2017-04-20 |
3M Innovative Properties Co |
Ligadores heterobifuncionales con segmentos polietilenglicol y conjugados modificadores de la respuesta inmunitaria elaborados a partir de los mismos.
|
EP3508219A1
(en)
|
2011-07-06 |
2019-07-10 |
GlaxoSmithKline Biologicals S.A. |
Self-replicating rna prime - protein boost vaccines
|
ES2656050T3
(es)
|
2011-07-06 |
2018-02-22 |
Glaxosmithkline Biologicals Sa |
Composiciones de combinación inmunogénica y usos de las mismas
|
US20130023736A1
(en)
|
2011-07-21 |
2013-01-24 |
Stanley Dale Harpstead |
Systems for drug delivery and monitoring
|
CN103702687A
(zh)
|
2011-07-29 |
2014-04-02 |
西莱克塔生物科技公司 |
产生体液和细胞毒性t淋巴细胞(ctl)免疫应答的合成纳米载体
|
WO2013061305A1
(en)
|
2011-10-28 |
2013-05-02 |
Novartis Ag |
Novel purine derivatives and their use in the treatment of disease
|
US9493517B2
(en)
|
2011-11-07 |
2016-11-15 |
Glaxosmithkline Biologicals Sa |
Conjugates comprising an antigen and a carrier molecule
|
WO2013108272A2
(en)
|
2012-01-20 |
2013-07-25 |
International Centre For Genetic Engineering And Biotechnology |
Blood stage malaria vaccine
|
CN105457021A
(zh)
|
2012-05-04 |
2016-04-06 |
辉瑞公司 |
前列腺相关抗原及基于疫苗的免疫治疗疗法
|
EP2849756A1
(en)
|
2012-05-16 |
2015-03-25 |
Novartis AG |
Dosage regimen for a pi-3 kinase inhibitor
|
EP2869842A1
(en)
|
2012-07-06 |
2015-05-13 |
Novartis AG |
Immunogenic compositions and uses thereof
|
WO2014107663A2
(en)
|
2013-01-07 |
2014-07-10 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for treating cutaneous t cell lymphoma
|
US9919029B2
(en)
|
2013-07-26 |
2018-03-20 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Methods and pharmaceutical compositions for the treatment of bacterial infections
|
SG10201803802YA
(en)
|
2013-11-05 |
2018-06-28 |
3M Innovative Properties Co |
Sesame oil based injection formulations
|
EP2870974A1
(en)
|
2013-11-08 |
2015-05-13 |
Novartis AG |
Salmonella conjugate vaccines
|
KR20160095035A
(ko)
|
2013-12-06 |
2016-08-10 |
노파르티스 아게 |
알파-이소형 선택성 포스파티딜이노시톨 3-키나제 억제제를 위한 투여 요법
|
WO2015092592A1
(en)
|
2013-12-17 |
2015-06-25 |
Pfizer Inc. |
Novel 3,4-disubstituted-1h-pyrrolo[2,3-b]pyridines and 4,5-disubstituted-7h-pyrrolo[2,3-c]pyridazines as lrrk2 inhibitors
|
US10421971B2
(en)
|
2014-01-15 |
2019-09-24 |
The University Of Chicago |
Anti-tumor therapy
|
JP6894237B2
(ja)
|
2014-03-26 |
2021-06-30 |
グラクソスミスクライン バイオロジカルズ ソシエテ アノニム |
変異体ブドウ球菌抗原
|
WO2016044839A2
(en)
|
2014-09-19 |
2016-03-24 |
The Board Of Regents Of The University Of Texas System |
Compositions and methods for treating viral infections through stimulated innate immunity in combination with antiviral compounds
|
CN108137586B
(zh)
|
2015-09-14 |
2021-04-13 |
辉瑞大药厂 |
作为LRRK2抑制剂的新颖咪唑并[4,5-c]喹啉和咪唑并[4,5-c][1,5]萘啶衍生物
|
US10526309B2
(en)
|
2015-10-02 |
2020-01-07 |
The University Of North Carolina At Chapel Hill |
Pan-TAM inhibitors and Mer/Axl dual inhibitors
|
JP2018532750A
(ja)
|
2015-11-02 |
2018-11-08 |
ノバルティス アーゲー |
ホスファチジルイノシトール3−キナーゼ阻害剤の投薬レジメン
|
US11697851B2
(en)
|
2016-05-24 |
2023-07-11 |
The Regents Of The University Of California |
Early ovarian cancer detection diagnostic test based on mRNA isoforms
|
WO2018060833A1
(en)
|
2016-09-27 |
2018-04-05 |
Novartis Ag |
Dosage regimen for alpha-isoform selective phosphatidylinositol 3-kinase inhibitor alpelisib
|
IL266562B1
(en)
|
2016-11-09 |
2024-07-01 |
Univ Texas |
Pharmaceutical compositions for immune regulation adapted for use in the patient sensitive to allergen-induced asthma
|
CN111511740B
(zh)
|
2017-12-20 |
2023-05-16 |
3M创新有限公司 |
用作免疫应答调节剂的带有支链连接基团的酰胺取代的咪唑并[4,5-c]喹啉化合物
|
CN109970572B
(zh)
*
|
2017-12-22 |
2022-04-22 |
万华化学集团股份有限公司 |
一种双键封端化合物的合成方法
|
US11059876B2
(en)
|
2018-02-28 |
2021-07-13 |
Pfizer Inc. |
IL-15 variants and uses thereof
|
JP7384835B2
(ja)
|
2018-05-23 |
2023-11-21 |
ファイザー・インク |
Cd3に特異的な抗体及びその使用
|
MX2020012607A
(es)
|
2018-05-23 |
2021-01-29 |
Pfizer |
Anticuerpos especificos para gucy2c y sus usos.
|
WO2020128893A1
(en)
|
2018-12-21 |
2020-06-25 |
Pfizer Inc. |
Combination treatments of cancer comprising a tlr agonist
|
WO2021116420A1
(en)
|
2019-12-13 |
2021-06-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of tlr7 and/or tlr8 agonists for the treatment of leptospirosis
|
CA3164623A1
(en)
|
2019-12-17 |
2021-06-24 |
Pfizer Inc. |
Antibodies specific for cd47, pd-l1, and uses thereof
|
AU2021308586A1
(en)
|
2020-07-17 |
2023-03-02 |
Pfizer Inc. |
Therapeutic antibodies and their uses
|