CS276993B6 - Oxadiazolylalkylpurine derivatives, processes of their preparation and pharmaceuticals comprising thereof - Google Patents

Oxadiazolylalkylpurine derivatives, processes of their preparation and pharmaceuticals comprising thereof Download PDF

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Publication number
CS276993B6
CS276993B6 CS877327A CS732787A CS276993B6 CS 276993 B6 CS276993 B6 CS 276993B6 CS 877327 A CS877327 A CS 877327A CS 732787 A CS732787 A CS 732787A CS 276993 B6 CS276993 B6 CS 276993B6
Authority
CS
Czechoslovakia
Prior art keywords
methyl
dihydro
oxadiazol
dione
purine
Prior art date
Application number
CS877327A
Other languages
Czech (cs)
English (en)
Other versions
CS732787A3 (en
Inventor
Dezso Dr Ing Korbonits
Emil Dr Minker
Zoltan Dr Vargai
Gergely Dr Ing Heja
Gabor Dr Ing Kovacs
Agnes Dr Ing Gottsegen
Sandor Dr Ing Antus
Sandor Dr Virag
Andrea Ing Bolehovszky
Jeno Dr Marton
Katalin Ing Marmarosi
Lorand Dr Debreczeni
Laszlo Dr Tardos
Peter Dr Kormoczy
Vera Dr Gergely
Gabor Dr Horvath
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of CS732787A3 publication Critical patent/CS732787A3/cs
Publication of CS276993B6 publication Critical patent/CS276993B6/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
CS877327A 1986-10-09 1987-10-09 Oxadiazolylalkylpurine derivatives, processes of their preparation and pharmaceuticals comprising thereof CS276993B6 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU864230A HU197574B (en) 1986-10-09 1986-10-09 Process for production of derivatives of 3,7-dihydro-3-methil-7-//1,2,4-oxadiasole/-3-il/alkylenil/-1h-purin-2,6-dion and medical compositions containing these substances

Publications (2)

Publication Number Publication Date
CS732787A3 CS732787A3 (en) 1992-04-15
CS276993B6 true CS276993B6 (en) 1992-11-18

Family

ID=10967389

Family Applications (1)

Application Number Title Priority Date Filing Date
CS877327A CS276993B6 (en) 1986-10-09 1987-10-09 Oxadiazolylalkylpurine derivatives, processes of their preparation and pharmaceuticals comprising thereof

Country Status (28)

Country Link
US (1) US4840949A (fi)
EP (1) EP0264081B1 (fi)
JP (1) JPS63107980A (fi)
KR (1) KR960003612B1 (fi)
CN (1) CN1018644B (fi)
AT (1) ATE99685T1 (fi)
AU (1) AU595384B2 (fi)
BG (1) BG60403B2 (fi)
CS (1) CS276993B6 (fi)
CY (1) CY1843A (fi)
DD (1) DD262658A5 (fi)
DE (1) DE3788701D1 (fi)
DK (1) DK167806B1 (fi)
ES (1) ES2061465T3 (fi)
FI (1) FI87215C (fi)
GE (3) GEP19970842B (fi)
HK (1) HK78995A (fi)
HU (1) HU197574B (fi)
IL (1) IL84030A (fi)
LT (1) LT3685B (fi)
LV (1) LV10868B (fi)
NO (1) NO166323C (fi)
PL (2) PL268147A1 (fi)
RU (1) RU2007404C1 (fi)
SU (2) SU1602862A1 (fi)
UA (2) UA26368A (fi)
YU (1) YU47545B (fi)
ZA (1) ZA877333B (fi)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU197574B (en) * 1986-10-09 1989-04-28 Chinoin Gyogyszer Es Vegyeszet Process for production of derivatives of 3,7-dihydro-3-methil-7-//1,2,4-oxadiasole/-3-il/alkylenil/-1h-purin-2,6-dion and medical compositions containing these substances
IT1199320B (it) * 1986-12-16 1988-12-30 Malesci Sas 8-azaxantine alchilaminoalchil o eterociclilalchil sostituite sul nucleo triazolico,loro sali fisiologicamente accettabili,loro composizioni farmaceutiche ad attivita'antibroncospastica e relativo procedimento di preparazione
HU198933B (en) * 1987-11-02 1989-12-28 Chinoin Gyogyszer Es Vegyeszet Process for producing new xanthine derivatives and pharmaceutical compositions comprising same as active ingredient
HU206884B (en) * 1990-11-22 1993-01-28 Chinoin Gyogyszer Es Vegyeszet Process for producing purin derivatives and pharmaceutical compositions containing them
HUP9700654A2 (hu) 1997-03-26 1999-09-28 Dezső Korbonits Teobromin tartalmú köhögéscsillapító készítmények
US7914828B2 (en) * 2008-10-17 2011-03-29 Levine Brian M Combination herbal product to benefit respiratory tract
US8106234B2 (en) * 2009-05-07 2012-01-31 OptMed, Inc Methylidene malonate process
US10414839B2 (en) 2010-10-20 2019-09-17 Sirrus, Inc. Polymers including a methylene beta-ketoester and products formed therefrom
US8361519B2 (en) 2010-11-18 2013-01-29 Aadvantics Pharmaceuticals, Inc. Combination herbal product to benefit respiratory tract in people exposed to smoke
US9221739B2 (en) 2011-10-19 2015-12-29 Sirrus, Inc. Methylene beta-diketone monomers, methods for making methylene beta-diketone monomers, polymerizable compositions and products formed therefrom
JP6553505B2 (ja) 2012-03-30 2019-07-31 シラス・インコーポレイテッド 複合材およびラミネート物品ならびにこれらを作製するための重合系
EP3848402A1 (en) 2012-03-30 2021-07-14 Sirrus, Inc. Ink and coating formulations and polymerizable systems for producing the same
WO2013181600A2 (en) 2012-06-01 2013-12-05 Bioformix Inc. Optical material and articles formed therefrom
EP2920231B1 (en) 2012-11-16 2020-05-06 Sirrus, Inc. Plastics bonding systems and methods
US10607910B2 (en) 2012-11-30 2020-03-31 Sirrus, Inc. Composite compositions for electronics applications
US9334430B1 (en) 2015-05-29 2016-05-10 Sirrus, Inc. Encapsulated polymerization initiators, polymerization systems and methods using the same
US9217098B1 (en) 2015-06-01 2015-12-22 Sirrus, Inc. Electroinitiated polymerization of compositions having a 1,1-disubstituted alkene compound
RU2754735C1 (ru) * 2020-12-14 2021-09-06 Федеральное государственное бюджетное образовательное учреждение высшего образования "Ярославский государственный технический университет" ФГБОУВО "ЯГТУ" Способ получения 3,5-дизамещенных 1,2,4-оксадиазолов, содержащих алкенильный фрагмент

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU190377B (en) * 1982-03-12 1986-08-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing theophyllinyl-alkyl-oxadiazoles
HU197574B (en) * 1986-10-09 1989-04-28 Chinoin Gyogyszer Es Vegyeszet Process for production of derivatives of 3,7-dihydro-3-methil-7-//1,2,4-oxadiasole/-3-il/alkylenil/-1h-purin-2,6-dion and medical compositions containing these substances

Also Published As

Publication number Publication date
KR890006647A (ko) 1989-06-15
NO166323B (no) 1991-03-25
EP0264081B1 (de) 1994-01-05
DK167806B1 (da) 1993-12-20
UA5572A1 (uk) 1994-12-28
FI87215B (fi) 1992-08-31
RU2007404C1 (ru) 1994-02-15
CY1843A (en) 1996-03-08
AU7946287A (en) 1988-04-14
YU47545B (sh) 1995-10-03
LT3685B (en) 1996-01-25
HUT46003A (en) 1988-09-28
EP0264081A2 (de) 1988-04-20
NO874216L (no) 1988-04-11
ZA877333B (en) 1988-04-08
GEP19970817B (en) 1997-01-30
DD262658A5 (de) 1988-12-07
NO874216D0 (no) 1987-10-08
PL268147A1 (en) 1988-09-01
EP0264081A3 (en) 1989-11-15
IL84030A0 (en) 1988-02-29
HU197574B (en) 1989-04-28
IL84030A (en) 1991-01-31
DE3788701D1 (de) 1994-02-17
DK527087D0 (da) 1987-10-08
LV10868A (lv) 1995-10-20
DK527087A (da) 1988-04-10
ATE99685T1 (de) 1994-01-15
CN1018644B (zh) 1992-10-14
PL151110B1 (fi) 1990-08-31
FI874456A (fi) 1988-04-10
SU1635901A3 (ru) 1991-03-15
US4840949A (en) 1989-06-20
AU595384B2 (en) 1990-03-29
PL151206B1 (en) 1990-08-31
UA26368A (uk) 1999-08-30
BG60403B2 (bg) 1995-02-28
GEP19970842B (en) 1997-02-06
GEP19960657B (en) 1996-12-24
SU1602862A1 (ru) 1990-10-30
ES2061465T3 (es) 1994-12-16
CN87107785A (zh) 1988-07-20
FI87215C (fi) 1992-12-10
LTIP1455A (en) 1995-05-25
FI874456A0 (fi) 1987-10-09
JPH0546348B2 (fi) 1993-07-13
LV10868B (en) 1996-06-20
JPS63107980A (ja) 1988-05-12
HK78995A (en) 1995-05-26
YU185787A (sh) 1993-05-28
CS732787A3 (en) 1992-04-15
NO166323C (no) 1991-07-03
KR960003612B1 (ko) 1996-03-20

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of fee

Effective date: 19991009