CR20200522A - Inhibidor de ret para uso en tratar cáncer que tiene una alteración de ret - Google Patents
Inhibidor de ret para uso en tratar cáncer que tiene una alteración de retInfo
- Publication number
- CR20200522A CR20200522A CR20200522A CR20200522A CR20200522A CR 20200522 A CR20200522 A CR 20200522A CR 20200522 A CR20200522 A CR 20200522A CR 20200522 A CR20200522 A CR 20200522A CR 20200522 A CR20200522 A CR 20200522A
- Authority
- CR
- Costa Rica
- Prior art keywords
- ret
- treating cancer
- alteration
- inhibitor
- ret inhibitor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862652284P | 2018-04-03 | 2018-04-03 | |
| US201862656297P | 2018-04-11 | 2018-04-11 | |
| US201862657605P | 2018-04-13 | 2018-04-13 | |
| US201862741683P | 2018-10-05 | 2018-10-05 | |
| PCT/US2019/025655 WO2019195471A1 (en) | 2018-04-03 | 2019-04-03 | Ret inhibitor for use in treating cancer having a ret alteration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR20200522A true CR20200522A (es) | 2021-02-17 |
Family
ID=66223846
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR20200522A CR20200522A (es) | 2018-04-03 | 2019-04-03 | Inhibidor de ret para uso en tratar cáncer que tiene una alteración de ret |
Country Status (26)
| Country | Link |
|---|---|
| US (5) | US20210100795A1 (enExample) |
| EP (2) | EP3773589B1 (enExample) |
| JP (3) | JP7422084B2 (enExample) |
| KR (1) | KR20200139749A (enExample) |
| AU (1) | AU2019247766A1 (enExample) |
| BR (1) | BR112020020273A2 (enExample) |
| CA (1) | CA3096043A1 (enExample) |
| CL (1) | CL2020002544A1 (enExample) |
| CR (1) | CR20200522A (enExample) |
| DK (1) | DK3773589T3 (enExample) |
| ES (1) | ES2970041T3 (enExample) |
| FI (1) | FI3773589T3 (enExample) |
| HR (1) | HRP20240124T1 (enExample) |
| HU (1) | HUE065374T2 (enExample) |
| IL (1) | IL277629A (enExample) |
| LT (1) | LT3773589T (enExample) |
| MX (1) | MX2020010417A (enExample) |
| MY (1) | MY203645A (enExample) |
| PE (1) | PE20210096A1 (enExample) |
| PL (1) | PL3773589T3 (enExample) |
| PT (1) | PT3773589T (enExample) |
| RS (1) | RS65127B1 (enExample) |
| SG (1) | SG11202009681YA (enExample) |
| SI (1) | SI3773589T1 (enExample) |
| WO (1) | WO2019195471A1 (enExample) |
| ZA (1) | ZA202006072B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016127074A1 (en) | 2015-02-06 | 2016-08-11 | Blueprint Medicines Corporation | 2-(pyridin-3-yl)-pyrimidine derivatives as ret inhibitors |
| IL302209B2 (en) | 2015-11-02 | 2024-06-01 | Blueprint Medicines Corp | Inhibitors of ret |
| PT3773589T (pt) | 2018-04-03 | 2024-02-06 | Blueprint Medicines Corp | Inibidor de ret para utilização no tratamento de cancro com alteração de ret |
| US11666570B2 (en) * | 2019-07-11 | 2023-06-06 | The Board Of Trustees Of The Leland Stanford Junior University | Diagnosis and regulation of epidermal differentiation and cancer cell activity |
| CA3183728A1 (en) | 2020-05-29 | 2021-12-02 | Blueprint Medicines Corporation | Solid forms of pralsetinib |
| US11946935B2 (en) * | 2020-08-25 | 2024-04-02 | Regents Of The University Of Minnesota | Circulating tumor markers for meningiomas |
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| EP3740491A1 (en) | 2018-01-18 | 2020-11-25 | Array Biopharma, Inc. | Substituted pyrrolo[2,3-d]pyrimidines compounds as ret kinase inhibitors |
| CN108341782A (zh) | 2018-03-30 | 2018-07-31 | 南京哈柏医药科技有限公司 | 3-氨基-5-甲基吡唑的合成工艺 |
| PT3773589T (pt) | 2018-04-03 | 2024-02-06 | Blueprint Medicines Corp | Inibidor de ret para utilização no tratamento de cancro com alteração de ret |
| WO2020033838A2 (en) | 2018-08-10 | 2020-02-13 | Blueprint Medicines Corporation | Treatment of egfr-mutant cancer |
| CN111362923A (zh) | 2020-03-25 | 2020-07-03 | 魏威 | 制备ret抑制剂普拉塞替尼的方法、以及普拉塞替尼的中间体及其制备方法 |
| CN111440151A (zh) | 2020-03-25 | 2020-07-24 | 魏威 | 制备抗肿瘤药普拉赛替尼的方法 |
| CA3183728A1 (en) | 2020-05-29 | 2021-12-02 | Blueprint Medicines Corporation | Solid forms of pralsetinib |
| IL298525A (en) | 2020-05-29 | 2023-01-01 | Blueprint Medicines Corp | Pralsetinib pharmaceutical compositions |
| EP4255892A1 (en) | 2020-12-04 | 2023-10-11 | Blueprint Medicines Corporation | Method of preparing pralsetinib |
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2019
- 2019-04-03 PT PT197185317T patent/PT3773589T/pt unknown
- 2019-04-03 WO PCT/US2019/025655 patent/WO2019195471A1/en not_active Ceased
- 2019-04-03 CR CR20200522A patent/CR20200522A/es unknown
- 2019-04-03 DK DK19718531.7T patent/DK3773589T3/da active
- 2019-04-03 SI SI201930702T patent/SI3773589T1/sl unknown
- 2019-04-03 EP EP19718531.7A patent/EP3773589B1/en active Active
- 2019-04-03 MX MX2020010417A patent/MX2020010417A/es unknown
- 2019-04-03 JP JP2020553633A patent/JP7422084B2/ja active Active
- 2019-04-03 PL PL19718531.7T patent/PL3773589T3/pl unknown
- 2019-04-03 RS RS20240107A patent/RS65127B1/sr unknown
- 2019-04-03 EP EP23199171.2A patent/EP4353317A3/en not_active Withdrawn
- 2019-04-03 FI FIEP19718531.7T patent/FI3773589T3/fi active
- 2019-04-03 ES ES19718531T patent/ES2970041T3/es active Active
- 2019-04-03 KR KR1020207031426A patent/KR20200139749A/ko not_active Withdrawn
- 2019-04-03 HU HUE19718531A patent/HUE065374T2/hu unknown
- 2019-04-03 US US17/044,884 patent/US20210100795A1/en not_active Abandoned
- 2019-04-03 MY MYPI2020005148A patent/MY203645A/en unknown
- 2019-04-03 HR HRP20240124TT patent/HRP20240124T1/hr unknown
- 2019-04-03 SG SG11202009681YA patent/SG11202009681YA/en unknown
- 2019-04-03 AU AU2019247766A patent/AU2019247766A1/en not_active Withdrawn
- 2019-04-03 CA CA3096043A patent/CA3096043A1/en active Pending
- 2019-04-03 BR BR112020020273-8A patent/BR112020020273A2/pt not_active Application Discontinuation
- 2019-04-03 PE PE2020001523A patent/PE20210096A1/es unknown
- 2019-04-03 LT LTEPPCT/US2019/025655T patent/LT3773589T/lt unknown
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2020
- 2020-09-27 IL IL277629A patent/IL277629A/en unknown
- 2020-09-30 ZA ZA2020/06072A patent/ZA202006072B/en unknown
- 2020-10-01 CL CL2020002544A patent/CL2020002544A1/es unknown
- 2020-10-02 US US17/061,743 patent/US11963958B2/en active Active
- 2020-12-18 US US17/127,041 patent/US11273160B2/en active Active
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2021
- 2021-07-16 US US17/377,885 patent/US11872192B2/en active Active
- 2021-12-09 JP JP2021199945A patent/JP2022022391A/ja active Pending
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2023
- 2023-09-28 JP JP2023167564A patent/JP2023165937A/ja not_active Withdrawn
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2024
- 2024-03-15 US US18/606,346 patent/US20250041297A1/en active Pending
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