CL2021002966A1 - Combinación de inhibidores de pd-1 e inhibidores de lag-3 para mejorar la eficacia en el tratamiento del cancer. - Google Patents

Combinación de inhibidores de pd-1 e inhibidores de lag-3 para mejorar la eficacia en el tratamiento del cancer.

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Publication number
CL2021002966A1
CL2021002966A1 CL2021002966A CL2021002966A CL2021002966A1 CL 2021002966 A1 CL2021002966 A1 CL 2021002966A1 CL 2021002966 A CL2021002966 A CL 2021002966A CL 2021002966 A CL2021002966 A CL 2021002966A CL 2021002966 A1 CL2021002966 A1 CL 2021002966A1
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CL
Chile
Prior art keywords
inhibitors
lag
combination
inhibitor
cancer treatment
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CL2021002966A
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English (en)
Inventor
Glenn Kroog
Tasha N Sims
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Regeneron Pharma
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Publication date
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Publication of CL2021002966A1 publication Critical patent/CL2021002966A1/es

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Abstract

La presente descripción proporciona métodos para tratar o inhibir el crecimiento del cáncer que comprende seleccionar un paciente con cáncer y administrar una cantidad terapéuticamente eficaz de un inhibidor de LAG-3 en combinación con una cantidad terapéuticamente eficaz de un inhibidor de PD-1 (por ejemplo, un anticuerpo anti-PD-1 o fragmento de unión al antígeno de este). En determinadas modalidades, la administración del inhibidor de PD-1 mejora la eficacia de un inhibidor de LAG-3 (por ejemplo, un anticuerpo anti-LAG-3 o fragmento de unión al antígeno de este) en la inhibición del crecimiento del cáncer.
CL2021002966A 2019-05-13 2021-11-10 Combinación de inhibidores de pd-1 e inhibidores de lag-3 para mejorar la eficacia en el tratamiento del cancer. CL2021002966A1 (es)

Applications Claiming Priority (1)

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US201962847068P 2019-05-13 2019-05-13

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CL2021002966A1 true CL2021002966A1 (es) 2022-08-26

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US (1) US20220249659A1 (es)
EP (1) EP3969040A1 (es)
JP (1) JP2022532490A (es)
KR (1) KR20220007593A (es)
CN (1) CN113825527A (es)
AU (1) AU2020276242A1 (es)
BR (1) BR112021021713A2 (es)
CA (1) CA3136568A1 (es)
CL (1) CL2021002966A1 (es)
EA (1) EA202192528A1 (es)
IL (1) IL287728A (es)
MA (1) MA55965A (es)
MX (1) MX2021013815A (es)
SG (1) SG11202111262XA (es)
WO (1) WO2020232019A1 (es)

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CA3136568A1 (en) 2020-11-19
WO2020232019A1 (en) 2020-11-19
EP3969040A1 (en) 2022-03-23
AU2020276242A1 (en) 2021-12-02
US20220249659A1 (en) 2022-08-11
JP2022532490A (ja) 2022-07-15
MX2021013815A (es) 2021-12-14
CN113825527A (zh) 2021-12-21
IL287728A (en) 2021-12-01
MA55965A (fr) 2022-03-23
SG11202111262XA (en) 2021-11-29
EA202192528A1 (ru) 2022-01-27
BR112021021713A2 (pt) 2022-04-19
KR20220007593A (ko) 2022-01-18

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