MX384234B - Uso de pridopidina para el tratamiento de enfermedad de huntington. - Google Patents

Uso de pridopidina para el tratamiento de enfermedad de huntington.

Info

Publication number
MX384234B
MX384234B MX2015017307A MX2015017307A MX384234B MX 384234 B MX384234 B MX 384234B MX 2015017307 A MX2015017307 A MX 2015017307A MX 2015017307 A MX2015017307 A MX 2015017307A MX 384234 B MX384234 B MX 384234B
Authority
MX
Mexico
Prior art keywords
pridopidine
huntington
disease
patient
treatment
Prior art date
Application number
MX2015017307A
Other languages
English (en)
Other versions
MX2015017307A (es
Inventor
Teige Wickenberg Anna Kristina Sveinsdotter
Eli Eyal
Esther Lukasiewicz Hagai
Merav Bassan
Original Assignee
Prilenia Neurotherapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52105289&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX384234(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Prilenia Neurotherapeutics Ltd filed Critical Prilenia Neurotherapeutics Ltd
Publication of MX2015017307A publication Critical patent/MX2015017307A/es
Publication of MX384234B publication Critical patent/MX384234B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

La invención proporciona un método de tratamiento de un paciente humano afectado por la enfermedad de Huntington, que comprende la administración periódica vía oral de una composición farmacéutica que comprende pridopidina o una sal farmacéuticamente aceptable de la misma de tal manera que se administren más de 135 mg de pridopidina al paciente por día. Esta invención proporciona además un método de tratamiento de un paciente humano que padece de enfermedad de Huntington, que comprende administrar oralmente de manera periódica al paciente una composición farmacéutica que comprende clorhidrato de pridopidina de tal manera que se administren más de 90 mg de pridopidina al paciente por día.
MX2015017307A 2013-06-21 2014-06-19 Uso de pridopidina para el tratamiento de enfermedad de huntington. MX384234B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361837928P 2013-06-21 2013-06-21
US201361877832P 2013-09-13 2013-09-13
PCT/US2014/043204 WO2014205229A1 (en) 2013-06-21 2014-06-19 Use of high dose pridopidine for treating huntington's disease

Publications (2)

Publication Number Publication Date
MX2015017307A MX2015017307A (es) 2016-08-03
MX384234B true MX384234B (es) 2025-03-14

Family

ID=52105289

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015017307A MX384234B (es) 2013-06-21 2014-06-19 Uso de pridopidina para el tratamiento de enfermedad de huntington.

Country Status (24)

Country Link
US (1) US10322119B2 (es)
EP (1) EP3010506B1 (es)
JP (1) JP2016523862A (es)
KR (1) KR102316933B1 (es)
CN (1) CN105592848A (es)
AU (1) AU2014281414A1 (es)
BR (1) BR112015029918A2 (es)
CA (1) CA2913781C (es)
CL (1) CL2015003690A1 (es)
DK (1) DK3010506T3 (es)
EA (1) EA201690069A1 (es)
ES (1) ES2879631T3 (es)
HK (1) HK1221646A1 (es)
HU (1) HUE054783T2 (es)
IL (1) IL242804B (es)
MX (1) MX384234B (es)
PE (2) PE20160195A1 (es)
PH (1) PH12015502691A1 (es)
PL (1) PL3010506T3 (es)
SG (1) SG11201509729YA (es)
TW (1) TW201529069A (es)
UA (1) UA122999C2 (es)
UY (1) UY35624A (es)
WO (1) WO2014205229A1 (es)

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EP2611759A1 (en) 2010-09-03 2013-07-10 Ivax International Gmbh Deuterated analogs of pridopidine useful as dopaminergic stabilizers
TWI579272B (zh) 2011-12-08 2017-04-21 梯瓦製藥國際有限責任公司 普多比啶（ｐｒｉｄｏｐｉｄｉｎｅ）之氫溴酸鹽
US11090297B2 (en) 2013-06-21 2021-08-17 Prilenia Neurotherapeutics Ltd. Pridopidine for treating huntington's disease
EA201691454A1 (ru) * 2014-01-22 2017-01-30 Тева Фармасьютикалз Интернэшнл Гмбх Композиции придопидина модифицированного высвобождения
TW201613859A (en) 2014-06-30 2016-04-16 Teva Pharma Analogs of PRIDOPIDINE, their preparation and use
CA2970799A1 (en) 2014-12-22 2016-06-30 Teva Pharmaceuticals International Gmbh L-tartrate salt of pridopidine
US11471449B2 (en) * 2015-02-25 2022-10-18 Prilenia Neurotherapeutics Ltd. Use of pridopidine to improve cognitive function and for treating Alzheimer's disease
MX378579B (es) * 2015-02-25 2025-03-11 Prilenia Neurotherapeutics Ltd Uso de pridopidina para mejorar la funcion cognitiva y para tratamiento de enfermedad de alzheimer.
CA2993183A1 (en) * 2015-07-22 2017-01-26 Teva Pharmaceuticals International Gmbh Pridopidine base formulations and their use
AR105434A1 (es) 2015-07-22 2017-10-04 Teva Pharmaceuticals Int Gmbh Proceso para preparar pridopidina
DK3419622T3 (da) 2016-02-24 2024-06-03 Prilenia Neurotherapeutics Ltd Behandling af neurodegenerativ øjensygdom med pridopidin
MX2019002190A (es) 2016-08-24 2019-09-11 Prilenia Therapeutics Dev Ltd Uso de pridopidina para tratar distonías.
EP4516356A3 (en) * 2016-08-24 2025-05-14 Prilenia Neurotherapeutics Ltd. Use of pridopidine for treating functional decline
US20200375966A1 (en) * 2016-09-15 2020-12-03 Prilenia Therapeutics Development Ltd Use of pridopidine for the treatment of anxiety and depression
PL4005570T3 (pl) 2016-09-16 2024-09-23 Prilenia Neurotherapeutics Ltd. Pridopidyna do zastosowania w leczeniu zespołu retta
US12102627B2 (en) 2016-09-16 2024-10-01 Prilenia Neurotherapeutics Ltd. Use of pridopidine for treating rett syndrome
PL3570940T3 (pl) 2017-01-20 2024-06-17 Prilenia Neurotherapeutics Ltd. Pridopidyna do zastosowania w leczeniu zespołu łamliwego chromosomu x
EP4620471A3 (en) * 2017-08-14 2025-11-26 Prilenia Neurotherapeutics Ltd. Treating amyotrophic lateral sclerosis with pridopidine
EA202090542A1 (ru) 2017-08-30 2020-06-08 Приления Ньюротерапьютикс Лтд. Высококонцентрированные лекарственные формы придопидина
EP3678664A1 (en) 2017-09-08 2020-07-15 Prilenia Neurotherapeutics Ltd. Pridopidine for treating drug induced dyskinesias
US12036213B2 (en) 2017-09-08 2024-07-16 Prilenia Neurotherapeutics Ltd. Pridopidine for treating drug induced dyskinesias
CN113365551A (zh) * 2019-01-31 2021-09-07 豪夫迈·罗氏有限公司 评估亨廷顿氏病的进展
WO2020161707A1 (en) 2019-02-04 2020-08-13 Prilenia Neurotherapeutics Ltd. Low dose pridopidine for parkinson's disease and other diseases associated with parkinsonism
HRP20260072T1 (hr) * 2019-06-12 2026-02-27 Prilenia Neurotherapeutics Ltd. Supstanca koja obuhvaća pridopidin i njegov analog za liječenje huntingtonove bolesti i njezinih simptoma
WO2021055443A1 (en) * 2019-09-17 2021-03-25 Hoffmann-La Roche Inc. Improvements in personalized healthcare for patients with movement disorders
WO2022094565A1 (en) * 2020-10-28 2022-05-05 Buck Institute For Research On Aging N-propargylglycine: a unique inhibitor of proline dehydrogenase with brain-enhancing mitohormesis properties capable of mitigating neurodegenerative disorders
WO2025181805A1 (en) * 2024-02-27 2025-09-04 Prilenia Neurotherapeutics Ltd. Pridopidine and sigma 2 antagonist agent for treating huntington disease and symptoms thereof

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USRE46117E1 (en) 1999-12-22 2016-08-23 Teva Pharmaceuticals International Gmbh Modulators of dopamine neurotransmission
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CA2847736A1 (en) 2011-09-07 2013-03-14 IVAX International GmbH A new polymorphic form of pridopidine hydrochloride
TWI579272B (zh) * 2011-12-08 2017-04-21 梯瓦製藥國際有限責任公司 普多比啶（ｐｒｉｄｏｐｉｄｉｎｅ）之氫溴酸鹽
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JP6177875B2 (ja) 2012-04-04 2017-08-09 テバ・ファーマシューティカルズ・インターナショナル・ゲーエムベーハーＴｅｖａ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｔｅｒｎａｔｉｏｎａｌ ＧｍｂＨ 併用療法のための医薬組成物
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WO2014052935A2 (en) 2012-09-27 2014-04-03 Teva Pharmaceutical Industries Ltd. Combination of rasagiline and pridopidine for treating neurodegenerative disorders, in particular huntington's disease
EA201691454A1 (ru) 2014-01-22 2017-01-30 Тева Фармасьютикалз Интернэшнл Гмбх Композиции придопидина модифицированного высвобождения
TW201613859A (en) 2014-06-30 2016-04-16 Teva Pharma Analogs of PRIDOPIDINE, their preparation and use
CA2970799A1 (en) 2014-12-22 2016-06-30 Teva Pharmaceuticals International Gmbh L-tartrate salt of pridopidine
WO2016138135A1 (en) 2015-02-25 2016-09-01 Teva Pharmaceuticals International Gmbh Sigma-1 receptor modulators for treating huntington's disease
MX378579B (es) 2015-02-25 2025-03-11 Prilenia Neurotherapeutics Ltd Uso de pridopidina para mejorar la funcion cognitiva y para tratamiento de enfermedad de alzheimer.
AR105434A1 (es) 2015-07-22 2017-10-04 Teva Pharmaceuticals Int Gmbh Proceso para preparar pridopidina
CA2993183A1 (en) 2015-07-22 2017-01-26 Teva Pharmaceuticals International Gmbh Pridopidine base formulations and their use
WO2017048457A1 (en) 2015-09-18 2017-03-23 Teva Pharmaceuticals Industries Ltd. Combination of laquinimod and pridopidine to treat multiple sclerosis
EP4516356A3 (en) 2016-08-24 2025-05-14 Prilenia Neurotherapeutics Ltd. Use of pridopidine for treating functional decline
MX2019002190A (es) 2016-08-24 2019-09-11 Prilenia Therapeutics Dev Ltd Uso de pridopidina para tratar distonías.
US20200375966A1 (en) 2016-09-15 2020-12-03 Prilenia Therapeutics Development Ltd Use of pridopidine for the treatment of anxiety and depression
WO2018053275A1 (en) 2016-09-16 2018-03-22 Teva Pharmaceuticals International Gmbh Use of pridopidine for the treatment of familial dysautonomia
PL4005570T3 (pl) 2016-09-16 2024-09-23 Prilenia Neurotherapeutics Ltd. Pridopidyna do zastosowania w leczeniu zespołu retta

Also Published As

Publication number Publication date
US20140378508A1 (en) 2014-12-25
IL242804B (en) 2022-02-01
CA2913781C (en) 2022-05-10
CL2015003690A1 (es) 2016-10-28
AU2014281414A1 (en) 2016-01-21
ES2879631T3 (es) 2021-11-22
WO2014205229A8 (en) 2015-04-09
PE20160195A1 (es) 2016-05-14
KR102316933B1 (ko) 2021-10-26
HUE054783T2 (hu) 2021-09-28
PE20170302A1 (es) 2017-03-31
CN105592848A (zh) 2016-05-18
EP3010506A1 (en) 2016-04-27
BR112015029918A2 (pt) 2017-07-25
HK1221646A1 (zh) 2017-06-09
KR20160055122A (ko) 2016-05-17
US10322119B2 (en) 2019-06-18
TW201529069A (zh) 2015-08-01
UA122999C2 (uk) 2021-02-03
UY35624A (es) 2015-01-30
WO2014205229A1 (en) 2014-12-24
CA2913781A1 (en) 2014-12-24
EP3010506A4 (en) 2017-02-08
SG11201509729YA (en) 2015-12-30
PL3010506T3 (pl) 2021-11-02
EA201690069A1 (ru) 2016-06-30
MX2015017307A (es) 2016-08-03
JP2016523862A (ja) 2016-08-12
EP3010506B1 (en) 2021-05-12
DK3010506T3 (da) 2021-07-12
PH12015502691A1 (en) 2016-03-14

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