MX390627B - Uso de pridopidina para el tratamiento de la disminucion funcional. - Google Patents
Uso de pridopidina para el tratamiento de la disminucion funcional.Info
- Publication number
- MX390627B MX390627B MX2019002265A MX2019002265A MX390627B MX 390627 B MX390627 B MX 390627B MX 2019002265 A MX2019002265 A MX 2019002265A MX 2019002265 A MX2019002265 A MX 2019002265A MX 390627 B MX390627 B MX 390627B
- Authority
- MX
- Mexico
- Prior art keywords
- functional capacity
- pridopidine
- functional
- decreasing
- treatment
- Prior art date
Links
- YGKUEOZJFIXDGI-UHFFFAOYSA-N pridopidine Chemical compound C1CN(CCC)CCC1C1=CC=CC(S(C)(=O)=O)=C1 YGKUEOZJFIXDGI-UHFFFAOYSA-N 0.000 title abstract 3
- 229950003764 pridopidine Drugs 0.000 title abstract 3
- 230000003247 decreasing effect Effects 0.000 title 1
- 230000007423 decrease Effects 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Psychology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Esta invención proporciona un método para mantener la capacidad funcional, mejorar la capacidad funcional o retardar la disminución de la capacidad funcional en un paciente humano que comprende administrar periódicamente por vía oral al paciente una composición farmacéutica que comprende pridopidina de manera que se administre una dosis de 90-225 mg de pridopidina al paciente por día, para mantener así la capacidad funcional, mejorar la capacidad funcional o retardar la disminución de la capacidad funcional en el paciente humano.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662379175P | 2016-08-24 | 2016-08-24 | |
| US201662395263P | 2016-09-15 | 2016-09-15 | |
| US201662411511P | 2016-10-21 | 2016-10-21 | |
| US201662416685P | 2016-11-02 | 2016-11-02 | |
| PCT/US2017/048461 WO2018039477A1 (en) | 2016-08-24 | 2017-08-24 | Use of pridopidine for treating functional decline |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2019002265A MX2019002265A (es) | 2019-10-30 |
| MX390627B true MX390627B (es) | 2025-03-21 |
Family
ID=61241181
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019002265A MX390627B (es) | 2016-08-24 | 2017-08-24 | Uso de pridopidina para el tratamiento de la disminucion funcional. |
| MX2022003072A MX2022003072A (es) | 2016-08-24 | 2019-02-25 | Uso de pridopidina para el tratamiento de la disminucion funcional. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2022003072A MX2022003072A (es) | 2016-08-24 | 2019-02-25 | Uso de pridopidina para el tratamiento de la disminucion funcional. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US11207310B2 (es) |
| EP (2) | EP4516356A3 (es) |
| JP (2) | JP6912574B2 (es) |
| CN (2) | CN115671103A (es) |
| AU (2) | AU2017315783C1 (es) |
| BR (1) | BR112019003732A2 (es) |
| CA (2) | CA3035092C (es) |
| CL (2) | CL2019000485A1 (es) |
| DK (1) | DK3504187T3 (es) |
| ES (1) | ES3025836T3 (es) |
| FI (1) | FI3504187T3 (es) |
| HU (1) | HUE071008T2 (es) |
| IL (1) | IL311081A (es) |
| MX (2) | MX390627B (es) |
| PL (1) | PL3504187T3 (es) |
| PT (1) | PT3504187T (es) |
| WO (1) | WO2018039477A1 (es) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2611759A1 (en) | 2010-09-03 | 2013-07-10 | Ivax International Gmbh | Deuterated analogs of pridopidine useful as dopaminergic stabilizers |
| US11090297B2 (en) | 2013-06-21 | 2021-08-17 | Prilenia Neurotherapeutics Ltd. | Pridopidine for treating huntington's disease |
| SG11201509729YA (en) | 2013-06-21 | 2015-12-30 | Teva Pharmaceuticals Int Gmbh | Use of high dose pridopidine for treating huntington's disease |
| TW201613859A (en) * | 2014-06-30 | 2016-04-16 | Teva Pharma | Analogs of PRIDOPIDINE, their preparation and use |
| US11471449B2 (en) | 2015-02-25 | 2022-10-18 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine to improve cognitive function and for treating Alzheimer's disease |
| MX378579B (es) | 2015-02-25 | 2025-03-11 | Prilenia Neurotherapeutics Ltd | Uso de pridopidina para mejorar la funcion cognitiva y para tratamiento de enfermedad de alzheimer. |
| EP4516356A3 (en) | 2016-08-24 | 2025-05-14 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine for treating functional decline |
| MX2019002190A (es) | 2016-08-24 | 2019-09-11 | Prilenia Therapeutics Dev Ltd | Uso de pridopidina para tratar distonías. |
| BR112019003320B1 (pt) | 2016-09-15 | 2024-02-20 | Boehringer Ingelheim International Gmbh | Compostos de heteroaril carboxamida, sal farmaceuticamente aceitável dos mesmos, composição farmacêutica e seus usos como inibidores de ripk2 |
| US12102627B2 (en) | 2016-09-16 | 2024-10-01 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine for treating rett syndrome |
| US12036213B2 (en) | 2017-09-08 | 2024-07-16 | Prilenia Neurotherapeutics Ltd. | Pridopidine for treating drug induced dyskinesias |
| EP3678664A1 (en) | 2017-09-08 | 2020-07-15 | Prilenia Neurotherapeutics Ltd. | Pridopidine for treating drug induced dyskinesias |
| CN113365551A (zh) * | 2019-01-31 | 2021-09-07 | 豪夫迈·罗氏有限公司 | 评估亨廷顿氏病的进展 |
| WO2020161707A1 (en) | 2019-02-04 | 2020-08-13 | Prilenia Neurotherapeutics Ltd. | Low dose pridopidine for parkinson's disease and other diseases associated with parkinsonism |
| HRP20260072T1 (hr) * | 2019-06-12 | 2026-02-27 | Prilenia Neurotherapeutics Ltd. | Supstanca koja obuhvaća pridopidin i njegov analog za liječenje huntingtonove bolesti i njezinih simptoma |
| AU2021266476B2 (en) * | 2020-05-04 | 2024-10-10 | Prilenia Neurotherapeutics Ltd. | Treatment of viral infection, disease or disorder using a selective S1R agonist |
| EP4322946A4 (en) * | 2021-04-14 | 2025-02-26 | Prilenia Neurotherapeutics Ltd. | TREATMENT OF PRODROMAL HUNTINGTON'S DISEASE |
| WO2025164698A1 (ja) * | 2024-01-31 | 2025-08-07 | 株式会社ケイファーマ | ハンチントン病治療剤及び治療用組成物 |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9702716D0 (sv) | 1997-07-15 | 1997-07-15 | Ross Nicholas Waters | Substituted phenylazacycloalkanes in the treatment of cognitive disorders |
| USRE46117E1 (en) | 1999-12-22 | 2016-08-23 | Teva Pharmaceuticals International Gmbh | Modulators of dopamine neurotransmission |
| SE9904724D0 (sv) | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission I |
| EP1713486A4 (en) * | 2003-12-02 | 2009-04-29 | Sheldon Leslie James | COMBINED THERAPY FOR THE TREATMENT OF DEMENTIA, DEPRESSION AND APATHY |
| GT200500063A (es) | 2004-04-01 | 2005-10-14 | Metodo para tratar la esquizofrenia y/o anormalidades glucoregulatorias | |
| WO2006040155A1 (en) | 2004-10-13 | 2006-04-20 | Neurosearch Sweden Ab | Process for the synthesis of 4-(3-methanesulfonylphenyl)-1-n-propyl-piperidine |
| DOP2006000273A (es) | 2005-12-08 | 2007-10-15 | Aventis Pharma Inc | Uso de un antagonista de cb1 para tratar efectos secundarios y sintomas negativos de la esquizofrenia |
| EP1815857A1 (en) | 2006-02-02 | 2007-08-08 | LEK Pharmaceuticals D.D. | A pharmaceutical composition comprising perindopril |
| US20070286902A1 (en) | 2006-06-07 | 2007-12-13 | Abrika Pharmaceuticals | Dosage forms comprising a short acting sedative-hypnotic or salt thereof |
| WO2008127188A1 (en) | 2007-04-12 | 2008-10-23 | Allbay Ab | N-oxide and/or di-n-oxide derivatives of dopamine receptor stabilizers/modulators displaying improved cardiovascular side-effects profiles |
| US8669048B2 (en) * | 2008-06-24 | 2014-03-11 | Parkinson's Institute | Pluripotent cell lines and methods of use thereof |
| US8384755B2 (en) | 2009-08-26 | 2013-02-26 | Intouch Technologies, Inc. | Portable remote presence robot |
| KR101762460B1 (ko) | 2009-09-24 | 2017-07-27 | 캡슈겔 벨지엄 엔브이 | 내산성 캡슐 |
| US20110206782A1 (en) | 2010-02-24 | 2011-08-25 | Auspex Pharmaceuticals, Inc. | Piperidine modulators of dopamine receptor |
| WO2011107583A1 (en) * | 2010-03-04 | 2011-09-09 | Nsab, Filial Af Neurosearch Sweden Ab, Sverige | Substituted 4-phenyl-n-alkyl-piperidines for preventing onset or slowing progression of neurodegenerative disorders |
| US20130216856A1 (en) | 2010-07-02 | 2013-08-22 | Marco Burtchen | Mechanical component and method of surface hardening |
| EP2611759A1 (en) | 2010-09-03 | 2013-07-10 | Ivax International Gmbh | Deuterated analogs of pridopidine useful as dopaminergic stabilizers |
| US8703763B2 (en) | 2011-03-02 | 2014-04-22 | Hoffmann-La Roche Inc. | Bridged piperidine derivatives |
| EP2710041A4 (en) | 2011-05-18 | 2014-11-05 | Parkinson S Inst | ASSAY FOR DETERMINING LRRK2 ACTIVITY IN MORBUS PARKINSON |
| CA2847736A1 (en) | 2011-09-07 | 2013-03-14 | IVAX International GmbH | A new polymorphic form of pridopidine hydrochloride |
| TWI579272B (zh) | 2011-12-08 | 2017-04-21 | 梯瓦製藥國際有限責任公司 | 普多比啶(pridopidine)之氫溴酸鹽 |
| US9744155B2 (en) * | 2012-03-28 | 2017-08-29 | Ixcela, Inc. | IPA as a therapeutic agent, as a protective agent, and as a biomarker of disease risk |
| JP6177875B2 (ja) | 2012-04-04 | 2017-08-09 | テバ・ファーマシューティカルズ・インターナショナル・ゲーエムベーハーTeva Pharmaceuticals International GmbH | 併用療法のための医薬組成物 |
| IN2015DN03219A (es) | 2012-09-27 | 2015-10-02 | Teva Pharma | |
| WO2014052935A2 (en) | 2012-09-27 | 2014-04-03 | Teva Pharmaceutical Industries Ltd. | Combination of rasagiline and pridopidine for treating neurodegenerative disorders, in particular huntington's disease |
| SG11201509729YA (en) * | 2013-06-21 | 2015-12-30 | Teva Pharmaceuticals Int Gmbh | Use of high dose pridopidine for treating huntington's disease |
| US11090297B2 (en) | 2013-06-21 | 2021-08-17 | Prilenia Neurotherapeutics Ltd. | Pridopidine for treating huntington's disease |
| EA201691454A1 (ru) | 2014-01-22 | 2017-01-30 | Тева Фармасьютикалз Интернэшнл Гмбх | Композиции придопидина модифицированного высвобождения |
| TW201613859A (en) | 2014-06-30 | 2016-04-16 | Teva Pharma | Analogs of PRIDOPIDINE, their preparation and use |
| CA2970799A1 (en) | 2014-12-22 | 2016-06-30 | Teva Pharmaceuticals International Gmbh | L-tartrate salt of pridopidine |
| MX378579B (es) | 2015-02-25 | 2025-03-11 | Prilenia Neurotherapeutics Ltd | Uso de pridopidina para mejorar la funcion cognitiva y para tratamiento de enfermedad de alzheimer. |
| WO2016138135A1 (en) | 2015-02-25 | 2016-09-01 | Teva Pharmaceuticals International Gmbh | Sigma-1 receptor modulators for treating huntington's disease |
| AR105434A1 (es) | 2015-07-22 | 2017-10-04 | Teva Pharmaceuticals Int Gmbh | Proceso para preparar pridopidina |
| CA2993183A1 (en) | 2015-07-22 | 2017-01-26 | Teva Pharmaceuticals International Gmbh | Pridopidine base formulations and their use |
| WO2017048457A1 (en) | 2015-09-18 | 2017-03-23 | Teva Pharmaceuticals Industries Ltd. | Combination of laquinimod and pridopidine to treat multiple sclerosis |
| DK3419622T3 (da) | 2016-02-24 | 2024-06-03 | Prilenia Neurotherapeutics Ltd | Behandling af neurodegenerativ øjensygdom med pridopidin |
| EP4516356A3 (en) | 2016-08-24 | 2025-05-14 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine for treating functional decline |
| MX2019002190A (es) | 2016-08-24 | 2019-09-11 | Prilenia Therapeutics Dev Ltd | Uso de pridopidina para tratar distonías. |
| US20200375966A1 (en) | 2016-09-15 | 2020-12-03 | Prilenia Therapeutics Development Ltd | Use of pridopidine for the treatment of anxiety and depression |
| WO2018053275A1 (en) | 2016-09-16 | 2018-03-22 | Teva Pharmaceuticals International Gmbh | Use of pridopidine for the treatment of familial dysautonomia |
| PL4005570T3 (pl) | 2016-09-16 | 2024-09-23 | Prilenia Neurotherapeutics Ltd. | Pridopidyna do zastosowania w leczeniu zespołu retta |
| PL3570940T3 (pl) | 2017-01-20 | 2024-06-17 | Prilenia Neurotherapeutics Ltd. | Pridopidyna do zastosowania w leczeniu zespołu łamliwego chromosomu x |
| EP4620471A3 (en) | 2017-08-14 | 2025-11-26 | Prilenia Neurotherapeutics Ltd. | Treating amyotrophic lateral sclerosis with pridopidine |
| EA202090542A1 (ru) | 2017-08-30 | 2020-06-08 | Приления Ньюротерапьютикс Лтд. | Высококонцентрированные лекарственные формы придопидина |
-
2017
- 2017-08-24 EP EP25152698.4A patent/EP4516356A3/en active Pending
- 2017-08-24 AU AU2017315783A patent/AU2017315783C1/en active Active
- 2017-08-24 CA CA3035092A patent/CA3035092C/en active Active
- 2017-08-24 BR BR112019003732-2A patent/BR112019003732A2/pt not_active Application Discontinuation
- 2017-08-24 CN CN202211419342.8A patent/CN115671103A/zh active Pending
- 2017-08-24 US US15/685,993 patent/US11207310B2/en active Active
- 2017-08-24 EP EP17844433.7A patent/EP3504187B8/en active Active
- 2017-08-24 CN CN201780066778.4A patent/CN109923102B/zh active Active
- 2017-08-24 MX MX2019002265A patent/MX390627B/es unknown
- 2017-08-24 FI FIEP17844433.7T patent/FI3504187T3/fi active
- 2017-08-24 DK DK17844433.7T patent/DK3504187T3/da active
- 2017-08-24 PT PT178444337T patent/PT3504187T/pt unknown
- 2017-08-24 CA CA3151507A patent/CA3151507C/en active Active
- 2017-08-24 IL IL311081A patent/IL311081A/en unknown
- 2017-08-24 PL PL17844433.7T patent/PL3504187T3/pl unknown
- 2017-08-24 JP JP2019531547A patent/JP6912574B2/ja active Active
- 2017-08-24 ES ES17844433T patent/ES3025836T3/es active Active
- 2017-08-24 HU HUE17844433A patent/HUE071008T2/hu unknown
- 2017-08-24 WO PCT/US2017/048461 patent/WO2018039477A1/en not_active Ceased
-
2019
- 2019-02-22 CL CL2019000485A patent/CL2019000485A1/es unknown
- 2019-02-25 MX MX2022003072A patent/MX2022003072A/es unknown
- 2019-12-31 CL CL2019003924A patent/CL2019003924A1/es unknown
-
2020
- 2020-08-27 AU AU2020223736A patent/AU2020223736B2/en active Active
-
2021
- 2021-05-06 JP JP2021078504A patent/JP2021119186A/ja active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX390627B (es) | Uso de pridopidina para el tratamiento de la disminucion funcional. | |
| MX384234B (es) | Uso de pridopidina para el tratamiento de enfermedad de huntington. | |
| MX2024010140A (es) | Nuevos metodos. | |
| MX2021004639A (es) | Combinaciones de inhibidores de desmetilasa-1 especifica de lisina (lsd1) para uso en el tratamiento de tumores solidos. | |
| MX2020004467A (es) | Metodos para el tratamiento o la prevencion del asma mediante la administracion de antagonista de il-4r. | |
| CY1119490T1 (el) | Παραγωγα πυραζολοπυρρολιδινης και η χρηση τους στην θεραπεια νοσηματων | |
| MX378579B (es) | Uso de pridopidina para mejorar la funcion cognitiva y para tratamiento de enfermedad de alzheimer. | |
| MX379286B (es) | INHIBIDORES DE PCSK9 PARA USARSE EN EL TRATAMIENTO DE PACIENTES CON HIPERCOLESTEROLEMIA FAMILIAR HETEROCIGOTA (HFHe). | |
| MX2021013139A (es) | Composicion farmaceutica para la prevencion y/o tratamiento de dermatitis atopica que comprende antagonista de interleucina 31 (il-31) como ingrediente activo. | |
| CR20180253A (es) | Composiciones terapéuticas para el tratamiento del virus de unmunodeficiencia humana | |
| MX2023014492A (es) | Compuestos utiles en la terapia para el vih. | |
| EA201492010A1 (ru) | Применение высокой дозы лахинимода для лечения рассеянного склероза | |
| SG10201805267UA (en) | Piperazine derivatives having multimodal activity against pain | |
| TW201613578A (en) | Pharmaceutical combinations | |
| PH12016502352A1 (en) | Pharmaceutical composition | |
| MX381440B (es) | Composicion farmaceutica para tratar colitis ulcerativa. | |
| MX379253B (es) | Formulaciones de oximetazolina estabilizadas y sus usos. | |
| MX374938B (es) | Un método para el tratamiento de trastornos del movimiento con befiradol. | |
| BR112015010223A2 (pt) | compostos tricíclicos para o uso no tratamento e/ou controle de obesidade | |
| BR112015015938A2 (pt) | uso de cloridrato de fenilefrina e paracetamol, medicamento, método de tratamento de congestão das mucosas do trato respiratório superior em um humano adulto | |
| MX2019009909A (es) | Composiciones farmaceuticas para terapia de combinacion. | |
| MX2018004774A (es) | Derivados de morfolina sustituidos que tienen actividad contra el dolor. | |
| MX384394B (es) | Compuesto para uso en la prevención y tratamiento de enfermedades neurodegenerativas. | |
| ECSP19024033A (es) | Composiciones de tesofensina | |
| EA202090416A1 (ru) | Способы лечения симптомов гастропареза с использованием велусетрага |