MX2020010417A - Inhibidor de ret para uso en tratar cancer que tiene una alteracion de ret. - Google Patents
Inhibidor de ret para uso en tratar cancer que tiene una alteracion de ret.Info
- Publication number
- MX2020010417A MX2020010417A MX2020010417A MX2020010417A MX2020010417A MX 2020010417 A MX2020010417 A MX 2020010417A MX 2020010417 A MX2020010417 A MX 2020010417A MX 2020010417 A MX2020010417 A MX 2020010417A MX 2020010417 A MX2020010417 A MX 2020010417A
- Authority
- MX
- Mexico
- Prior art keywords
- ret
- alteration
- treating cancer
- inhibitor
- ret inhibitor
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Se describe en la presente el tratamiento de un sujeto afectado por un cáncer que tiene una alteración de RET activadora al administrar una cantidad efectiva de un inhibidor de RET selectivo, por ejemplo, Compuesto 1 o sales farmacéuticamente aceptables del mismo, incluyendo, por ejemplo, administrar una cantidad de 300 mg a 400 mg del inhibidor de RET selectivo una vez al día.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862652284P | 2018-04-03 | 2018-04-03 | |
US201862656297P | 2018-04-11 | 2018-04-11 | |
US201862657605P | 2018-04-13 | 2018-04-13 | |
US201862741683P | 2018-10-05 | 2018-10-05 | |
PCT/US2019/025655 WO2019195471A1 (en) | 2018-04-03 | 2019-04-03 | Ret inhibitor for use in treating cancer having a ret alteration |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2020010417A true MX2020010417A (es) | 2021-01-08 |
Family
ID=66223846
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020010417A MX2020010417A (es) | 2018-04-03 | 2019-04-03 | Inhibidor de ret para uso en tratar cancer que tiene una alteracion de ret. |
Country Status (24)
Country | Link |
---|---|
US (4) | US20210100795A1 (es) |
EP (2) | EP4353317A3 (es) |
JP (3) | JP7422084B2 (es) |
KR (1) | KR20200139749A (es) |
AU (1) | AU2019247766A1 (es) |
BR (1) | BR112020020273A2 (es) |
CA (1) | CA3096043A1 (es) |
CL (1) | CL2020002544A1 (es) |
CR (1) | CR20200522A (es) |
DK (1) | DK3773589T3 (es) |
ES (1) | ES2970041T3 (es) |
FI (1) | FI3773589T3 (es) |
HR (1) | HRP20240124T1 (es) |
IL (1) | IL277629A (es) |
LT (1) | LT3773589T (es) |
MX (1) | MX2020010417A (es) |
PE (1) | PE20210096A1 (es) |
PL (1) | PL3773589T3 (es) |
PT (1) | PT3773589T (es) |
RS (1) | RS65127B1 (es) |
SG (1) | SG11202009681YA (es) |
SI (1) | SI3773589T1 (es) |
WO (1) | WO2019195471A1 (es) |
ZA (1) | ZA202006072B (es) |
Families Citing this family (5)
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US10202365B2 (en) | 2015-02-06 | 2019-02-12 | Blueprint Medicines Corporation | 2-(pyridin-3-yl)-pyrimidine derivatives as RET inhibitors |
JP6807385B2 (ja) | 2015-11-02 | 2021-01-06 | ブループリント メディシンズ コーポレイション | Retの阻害剤 |
CA3096043A1 (en) | 2018-04-03 | 2019-10-10 | Blueprint Medicines Corporation | Ret inhibitor for use in treating cancer having a ret alteration |
US11666570B2 (en) * | 2019-07-11 | 2023-06-06 | The Board Of Trustees Of The Leland Stanford Junior University | Diagnosis and regulation of epidermal differentiation and cancer cell activity |
US11946935B2 (en) * | 2020-08-25 | 2024-04-02 | Regents Of The University Of Minnesota | Circulating tumor markers for meningiomas |
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2019
- 2019-04-03 CA CA3096043A patent/CA3096043A1/en active Pending
- 2019-04-03 PL PL19718531.7T patent/PL3773589T3/pl unknown
- 2019-04-03 US US17/044,884 patent/US20210100795A1/en active Pending
- 2019-04-03 WO PCT/US2019/025655 patent/WO2019195471A1/en active Application Filing
- 2019-04-03 CR CR20200522A patent/CR20200522A/es unknown
- 2019-04-03 HR HRP20240124TT patent/HRP20240124T1/hr unknown
- 2019-04-03 JP JP2020553633A patent/JP7422084B2/ja active Active
- 2019-04-03 MX MX2020010417A patent/MX2020010417A/es unknown
- 2019-04-03 SG SG11202009681YA patent/SG11202009681YA/en unknown
- 2019-04-03 DK DK19718531.7T patent/DK3773589T3/da active
- 2019-04-03 AU AU2019247766A patent/AU2019247766A1/en active Pending
- 2019-04-03 BR BR112020020273-8A patent/BR112020020273A2/pt unknown
- 2019-04-03 LT LTEPPCT/US2019/025655T patent/LT3773589T/lt unknown
- 2019-04-03 EP EP23199171.2A patent/EP4353317A3/en active Pending
- 2019-04-03 ES ES19718531T patent/ES2970041T3/es active Active
- 2019-04-03 SI SI201930702T patent/SI3773589T1/sl unknown
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- 2019-04-03 PE PE2020001523A patent/PE20210096A1/es unknown
- 2019-04-03 KR KR1020207031426A patent/KR20200139749A/ko unknown
- 2019-04-03 EP EP19718531.7A patent/EP3773589B1/en active Active
- 2019-04-03 RS RS20240107A patent/RS65127B1/sr unknown
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2020
- 2020-09-27 IL IL277629A patent/IL277629A/en unknown
- 2020-09-30 ZA ZA2020/06072A patent/ZA202006072B/en unknown
- 2020-10-01 CL CL2020002544A patent/CL2020002544A1/es unknown
- 2020-10-02 US US17/061,743 patent/US11963958B2/en active Active
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2021
- 2021-07-16 US US17/377,885 patent/US11872192B2/en active Active
- 2021-12-09 JP JP2021199945A patent/JP2022022391A/ja active Pending
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2023
- 2023-09-28 JP JP2023167564A patent/JP2023165937A/ja active Pending
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