CR20140132A - Derivados de pirrolopirimidina y purina - Google Patents
Derivados de pirrolopirimidina y purinaInfo
- Publication number
- CR20140132A CR20140132A CR20140132A CR20140132A CR20140132A CR 20140132 A CR20140132 A CR 20140132A CR 20140132 A CR20140132 A CR 20140132A CR 20140132 A CR20140132 A CR 20140132A CR 20140132 A CR20140132 A CR 20140132A
- Authority
- CR
- Costa Rica
- Prior art keywords
- pirrolopirimidine
- purine derivatives
- purine
- derivatives
- compounds
- Prior art date
Links
- 229940083251 peripheral vasodilators purine derivative Drugs 0.000 title 1
- 150000003212 purines Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161538103P | 2011-09-22 | 2011-09-22 | |
| US201261639639P | 2012-04-27 | 2012-04-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR20140132A true CR20140132A (es) | 2014-05-16 |
Family
ID=47116127
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR20140132A CR20140132A (es) | 2011-09-22 | 2014-03-20 | Derivados de pirrolopirimidina y purina |
Country Status (29)
| Country | Link |
|---|---|
| US (2) | US9040547B2 (OSRAM) |
| EP (1) | EP2758402B9 (OSRAM) |
| JP (1) | JP5914667B2 (OSRAM) |
| KR (1) | KR20140059246A (OSRAM) |
| CN (1) | CN103814030A (OSRAM) |
| AP (1) | AP2014007475A0 (OSRAM) |
| AR (1) | AR088760A1 (OSRAM) |
| AU (1) | AU2012311184A1 (OSRAM) |
| BR (1) | BR112014006840A2 (OSRAM) |
| CA (1) | CA2847540C (OSRAM) |
| CL (2) | CL2014002726A1 (OSRAM) |
| CO (1) | CO6910196A2 (OSRAM) |
| CR (1) | CR20140132A (OSRAM) |
| DO (1) | DOP2014000055A (OSRAM) |
| EA (1) | EA201490673A1 (OSRAM) |
| ES (1) | ES2575710T3 (OSRAM) |
| IL (1) | IL231592A0 (OSRAM) |
| MA (1) | MA35451B1 (OSRAM) |
| MD (1) | MD20140023A2 (OSRAM) |
| MX (1) | MX2014003501A (OSRAM) |
| NI (1) | NI201400023A (OSRAM) |
| PE (1) | PE20141228A1 (OSRAM) |
| PH (1) | PH12014500638A1 (OSRAM) |
| SG (1) | SG2014014450A (OSRAM) |
| TN (1) | TN2014000115A1 (OSRAM) |
| TW (1) | TWI492946B (OSRAM) |
| UA (1) | UA110259C2 (OSRAM) |
| UY (1) | UY34342A (OSRAM) |
| WO (1) | WO2013042006A1 (OSRAM) |
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| EP2571361A4 (en) | 2010-05-19 | 2013-11-13 | Univ North Carolina | PYRAZOLOPYRIMIDINE COMPOUNDS FOR CANCER TREATMENT |
| LT2585470T (lt) * | 2010-06-23 | 2017-04-10 | Hanmi Science Co., Ltd. | Nauji kondensuoti pirimidino dariniai tirozino kinazės aktyvumo slopinimui |
| EP2704572B1 (en) | 2011-05-04 | 2015-12-30 | Ariad Pharmaceuticals, Inc. | Compounds for inhibiting cell proliferation in egfr-driven cancers |
| KR102063098B1 (ko) | 2011-10-03 | 2020-01-08 | 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 | 암 치료를 위한 피롤로피리미딘 화합물 |
| JP6469567B2 (ja) | 2012-05-05 | 2019-02-13 | アリアド・ファーマシューティカルズ・インコーポレイテッド | Ｅｇｆｒ発動性がんの細胞増殖阻害用化合物 |
| CN104302627A (zh) | 2012-05-22 | 2015-01-21 | 北卡罗来纳大学教堂山分校 | 用于治疗癌症的嘧啶化合物 |
| WO2014062774A1 (en) | 2012-10-17 | 2014-04-24 | The University Of North Carolina At Chapel Hill | Pyrazolopyrimidine compounds for the treatment of cancer |
| EP2925752A4 (en) | 2012-11-27 | 2016-06-01 | Univ North Carolina | PYRIMIDINE COMPOUNDS FOR CANCER TREATMENT |
| US9346812B2 (en) | 2013-01-16 | 2016-05-24 | Signal Pharmaceuticals, Llc | Substituted pyrrolopyrimidine compounds, compositions thereof, and methods of treatment therewith |
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| JP6427599B2 (ja) * | 2014-05-19 | 2018-11-21 | チャンスー ヘンルイ メディシン カンパニー，リミテッド | チロシンキナーゼ阻害剤としての置換エチニルヘテロ二環式化合物 |
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| KR102398659B1 (ko) * | 2017-03-17 | 2022-05-16 | 주식회사 대웅제약 | 카이네이즈 저해제로서의 피롤로트리아진 유도체 |
| US10807951B2 (en) | 2017-10-13 | 2020-10-20 | The Regents Of The University Of California | mTORC1 modulators |
| CA3083583A1 (en) * | 2017-12-05 | 2019-06-13 | Oscotec Inc. | Pyrrolo(pyrazolo)pyrimidine derivative as lrrk2 inhibitor |
| MX2020006799A (es) | 2017-12-28 | 2020-09-03 | Daewoong Pharmaceutical Co Ltd | Derivados de oxi-fluoropiperidina como inhibidor de cinasa. |
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| EP3842435A4 (en) * | 2018-09-20 | 2022-05-11 | Hanmi Pharm. Co., Ltd. | NEW SULFONAMIDE DERIVATIVE PRESENTING A FUSED PYRIMIDINE SKELETON, HAVING AN INHIBITOR EFFECT OF EPIDERMAL GROWTH FACTOR RECEPTOR MUTATION |
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