PE20141228A1 - Derivados de pirrolopirimidina y purina - Google Patents
Derivados de pirrolopirimidina y purinaInfo
- Publication number
- PE20141228A1 PE20141228A1 PE2014000403A PE2014000403A PE20141228A1 PE 20141228 A1 PE20141228 A1 PE 20141228A1 PE 2014000403 A PE2014000403 A PE 2014000403A PE 2014000403 A PE2014000403 A PE 2014000403A PE 20141228 A1 PE20141228 A1 PE 20141228A1
- Authority
- PE
- Peru
- Prior art keywords
- methyl
- independently
- cyane
- pyrrolopyrimidine
- purine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161538103P | 2011-09-22 | 2011-09-22 | |
| US201261639639P | 2012-04-27 | 2012-04-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20141228A1 true PE20141228A1 (es) | 2014-10-01 |
Family
ID=47116127
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2014000403A PE20141228A1 (es) | 2011-09-22 | 2012-09-10 | Derivados de pirrolopirimidina y purina |
Country Status (29)
| Country | Link |
|---|---|
| US (2) | US9040547B2 (OSRAM) |
| EP (1) | EP2758402B9 (OSRAM) |
| JP (1) | JP5914667B2 (OSRAM) |
| KR (1) | KR20140059246A (OSRAM) |
| CN (1) | CN103814030A (OSRAM) |
| AP (1) | AP2014007475A0 (OSRAM) |
| AR (1) | AR088760A1 (OSRAM) |
| AU (1) | AU2012311184A1 (OSRAM) |
| BR (1) | BR112014006840A2 (OSRAM) |
| CA (1) | CA2847540C (OSRAM) |
| CL (2) | CL2014002726A1 (OSRAM) |
| CO (1) | CO6910196A2 (OSRAM) |
| CR (1) | CR20140132A (OSRAM) |
| DO (1) | DOP2014000055A (OSRAM) |
| EA (1) | EA201490673A1 (OSRAM) |
| ES (1) | ES2575710T3 (OSRAM) |
| IL (1) | IL231592A0 (OSRAM) |
| MA (1) | MA35451B1 (OSRAM) |
| MD (1) | MD20140023A2 (OSRAM) |
| MX (1) | MX2014003501A (OSRAM) |
| NI (1) | NI201400023A (OSRAM) |
| PE (1) | PE20141228A1 (OSRAM) |
| PH (1) | PH12014500638A1 (OSRAM) |
| SG (1) | SG2014014450A (OSRAM) |
| TN (1) | TN2014000115A1 (OSRAM) |
| TW (1) | TWI492946B (OSRAM) |
| UA (1) | UA110259C2 (OSRAM) |
| UY (1) | UY34342A (OSRAM) |
| WO (1) | WO2013042006A1 (OSRAM) |
Families Citing this family (55)
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| CN103501612B (zh) | 2011-05-04 | 2017-03-29 | 阿里亚德医药股份有限公司 | 抑制表皮生长因子受体导致的癌症中细胞增殖的化合物 |
| CN103958510B (zh) | 2011-10-03 | 2016-10-19 | 北卡罗来纳大学教堂山分校 | 用于治疗癌症的吡咯并嘧啶化合物 |
| JP6469567B2 (ja) | 2012-05-05 | 2019-02-13 | アリアド・ファーマシューティカルズ・インコーポレイテッド | Egfr発動性がんの細胞増殖阻害用化合物 |
| CN104302627A (zh) | 2012-05-22 | 2015-01-21 | 北卡罗来纳大学教堂山分校 | 用于治疗癌症的嘧啶化合物 |
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| CN105524068B (zh) | 2014-09-30 | 2017-11-24 | 上海海雁医药科技有限公司 | 氮杂双环衍生物、其制法与医药上的用途 |
| CN105085489B (zh) * | 2014-11-05 | 2019-03-01 | 益方生物科技(上海)有限公司 | 嘧啶或吡啶类化合物、其制备方法和医药用途 |
| HK1245260A1 (zh) | 2014-12-23 | 2018-08-24 | Dana-Farber Cancer Institute, Inc. | 细胞周期蛋白依赖性激酶7(cdk7)的抑制剂 |
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| JP6861166B2 (ja) | 2015-03-27 | 2021-04-21 | ダナ−ファーバー キャンサー インスティテュート, インコーポレイテッド | サイクリン依存性キナーゼの阻害剤 |
| CN112932416A (zh) | 2015-06-04 | 2021-06-11 | 松下知识产权经营株式会社 | 生物体信息检测装置及生物体信息检测方法 |
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| EP3587422A4 (en) | 2017-02-22 | 2020-05-06 | Daegu-Gyeongbuk Medical Innovation Foundation | PYRROLO-PYRIMIDINE DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR THE PREVENTION OR TREATMENT OF A PROTEIN KINASE-RELATED DISEASE |
| KR102398659B1 (ko) * | 2017-03-17 | 2022-05-16 | 주식회사 대웅제약 | 카이네이즈 저해제로서의 피롤로트리아진 유도체 |
| WO2019075386A1 (en) | 2017-10-13 | 2019-04-18 | The Regents Of The University Of California | MODULATORS OF MTORC1 |
| CN111433208B (zh) * | 2017-12-05 | 2023-06-30 | 奥斯考泰克公司 | 作为lrrk2抑制剂的吡咯并(吡唑并)嘧啶衍生物 |
| KR102577242B1 (ko) * | 2017-12-28 | 2023-09-11 | 주식회사 대웅제약 | 카이네이즈 저해제로서의 아미노-메틸피페리딘 유도체 |
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