DE602005024382D1 - Polycyclische pyrimidine als kaliumionenkanal-modulatoren - Google Patents

Polycyclische pyrimidine als kaliumionenkanal-modulatoren

Info

Publication number
DE602005024382D1
DE602005024382D1 DE602005024382T DE602005024382T DE602005024382D1 DE 602005024382 D1 DE602005024382 D1 DE 602005024382D1 DE 602005024382 T DE602005024382 T DE 602005024382T DE 602005024382 T DE602005024382 T DE 602005024382T DE 602005024382 D1 DE602005024382 D1 DE 602005024382D1
Authority
DE
Germany
Prior art keywords
pyrimidines
polycyclic
caliumional
channel modulators
modulators
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005024382T
Other languages
English (en)
Inventor
Xiadong Wang
Kerry Leigh Spear
Alan Bradley Fulp
Darrick Seconi
Takeshi Suzuki
Takahiro Ishii
Ayako Moritomo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Inc
Icagen Inc
Original Assignee
Astellas Pharma Inc
Icagen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Pharma Inc, Icagen Inc filed Critical Astellas Pharma Inc
Publication of DE602005024382D1 publication Critical patent/DE602005024382D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
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    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
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    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
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    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
DE602005024382T 2004-04-13 2005-04-13 Polycyclische pyrimidine als kaliumionenkanal-modulatoren Active DE602005024382D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56199004P 2004-04-13 2004-04-13
PCT/US2005/012696 WO2005099711A1 (en) 2004-04-13 2005-04-13 Polycyclic pyrimidines as potassium ion channel modulators

Publications (1)

Publication Number Publication Date
DE602005024382D1 true DE602005024382D1 (de) 2010-12-09

Family

ID=34969928

Family Applications (1)

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DE602005024382T Active DE602005024382D1 (de) 2004-04-13 2005-04-13 Polycyclische pyrimidine als kaliumionenkanal-modulatoren

Country Status (8)

Country Link
US (1) US7560464B2 (de)
EP (1) EP1742634B1 (de)
JP (2) JP2007532669A (de)
AT (1) ATE485824T1 (de)
AU (1) AU2005232745A1 (de)
CA (1) CA2561895A1 (de)
DE (1) DE602005024382D1 (de)
WO (1) WO2005099711A1 (de)

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WO2009119528A1 (ja) * 2008-03-24 2009-10-01 武田薬品工業株式会社 複素環化合物
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WO2010026087A1 (en) * 2008-09-02 2010-03-11 Neurosearch A/S Pyrazolyl-pyrimidine derivatives and their use as potassium channel modulators
WO2010055114A1 (en) * 2008-11-14 2010-05-20 Bayer Cropscience Sa Substituted (pyridyl)-azinylamine derivatives as plant protection agents
GB0821307D0 (en) * 2008-11-21 2008-12-31 Summit Corp Plc Compounds for treatment of duchenne muscular dystrophy
US8415381B2 (en) 2009-07-30 2013-04-09 Novartis Ag Heteroaryl compounds and their uses
AR077999A1 (es) 2009-09-02 2011-10-05 Vifor Int Ag Antagonistas de pirimidin y triazin-hepcidina
DE102010002558A1 (de) 2009-11-20 2011-06-01 Symrise Ag Verwendung physiologischer Kühlwirkstoffe und Mittel enthaltend solche Wirkstoffe
AR079814A1 (es) * 2009-12-31 2012-02-22 Otsuka Pharma Co Ltd Compuestos heterociclicos, composiciones farmaceuticas que los contienen y sus usos
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JP5914667B2 (ja) 2011-09-22 2016-05-11 ファイザー・インク ピロロピリミジンおよびプリン誘導体
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JP2014237590A (ja) * 2011-09-30 2014-12-18 アステラス製薬株式会社 ２−（ピリジン−２−イル）ピリミジン−４−アミン化合物又はその塩
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AP2015008707A0 (en) 2013-03-14 2015-09-30 Novartis Ag 3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant idh
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US7560464B2 (en) 2009-07-14
JP2007532669A (ja) 2007-11-15
ATE485824T1 (de) 2010-11-15
JP2008247916A (ja) 2008-10-16
CA2561895A1 (en) 2005-10-27
US20050267089A1 (en) 2005-12-01
WO2005099711A1 (en) 2005-10-27
EP1742634B1 (de) 2010-10-27
EP1742634A1 (de) 2007-01-17
AU2005232745A1 (en) 2005-10-27

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