CO6341636A2 - Derivados de dioxa-biciclo[3.2.1]octano-2,3,4-triol - Google Patents

Derivados de dioxa-biciclo[3.2.1]octano-2,3,4-triol

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Publication number
CO6341636A2
CO6341636A2 CO11022222A CO11022222A CO6341636A2 CO 6341636 A2 CO6341636 A2 CO 6341636A2 CO 11022222 A CO11022222 A CO 11022222A CO 11022222 A CO11022222 A CO 11022222A CO 6341636 A2 CO6341636 A2 CO 6341636A2
Authority
CO
Colombia
Prior art keywords
dioxa
triol
octano
treatment
derivatives
Prior art date
Application number
CO11022222A
Other languages
English (en)
Inventor
Vincent Mascitti
Banjamin Micah Collman
Original Assignee
Pfizer
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41208284&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO6341636(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Publication of CO6341636A2 publication Critical patent/CO6341636A2/es

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08Bridged systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04Cyclic acetals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invención se refiere a derivados de dioxa-biciclo [3.2.1] octano-2,3,4-triol, y los usos de los mismos para el tratamiento de enfermedades, afecciones y/o trastornos mediados por inhibidores del transportador de glucosa dependiente de sodio (en particular, inhibidores de SGLT2). Los compuestos aquí revelados son útiles para la prevención y tratamiento de la obesidad y enfermedades asociadas, en particular a diabetes de Tipo II.
CO11022222A 2008-08-28 2011-02-23 Derivados de dioxa-biciclo[3.2.1]octano-2,3,4-triol CO6341636A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9247008P 2008-08-28 2008-08-28
US22721209P 2009-07-21 2009-07-21

Publications (1)

Publication Number Publication Date
CO6341636A2 true CO6341636A2 (es) 2011-11-21

Family

ID=41208284

Family Applications (1)

Application Number Title Priority Date Filing Date
CO11022222A CO6341636A2 (es) 2008-08-28 2011-02-23 Derivados de dioxa-biciclo[3.2.1]octano-2,3,4-triol

Country Status (47)

Country Link
US (1) US8080580B2 (es)
EP (1) EP2334687B9 (es)
JP (1) JP4825322B1 (es)
KR (2) KR101446454B1 (es)
CN (2) CN103497199B (es)
AP (1) AP2728A (es)
AR (1) AR073138A1 (es)
AT (1) ATE540040T1 (es)
AU (1) AU2009286380B2 (es)
BR (1) BRPI0918841B8 (es)
CA (1) CA2733795C (es)
CL (1) CL2011000394A1 (es)
CO (1) CO6341636A2 (es)
CR (1) CR20110077A (es)
CY (2) CY1112497T1 (es)
DK (1) DK2334687T5 (es)
DO (1) DOP2011000058A (es)
EA (1) EA018492B1 (es)
EC (1) ECSP11010854A (es)
ES (1) ES2380408T3 (es)
FR (1) FR18C1036I2 (es)
GE (1) GEP20135803B (es)
HK (2) HK1156616A1 (es)
HN (1) HN2009001652A (es)
HR (1) HRP20120104T1 (es)
HU (1) HUS1800031I1 (es)
IL (2) IL211226A (es)
LT (1) LTC2334687I2 (es)
MA (1) MA32590B1 (es)
ME (1) ME01285A (es)
MX (1) MX2011002166A (es)
MY (1) MY155418A (es)
NI (1) NI201100043A (es)
NL (1) NL300943I2 (es)
NO (1) NO2018019I2 (es)
NZ (1) NZ591027A (es)
PA (1) PA8840801A1 (es)
PE (1) PE20110288A1 (es)
PL (1) PL2334687T3 (es)
PT (1) PT2334687E (es)
RS (1) RS52236B (es)
SI (1) SI2334687T1 (es)
SV (1) SV2011003842A (es)
TW (1) TWI387598B (es)
UY (1) UY32073A (es)
WO (1) WO2010023594A1 (es)
ZA (1) ZA201101341B (es)

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