PA8655401A1 - Nueva composicion farmaceutica que contiene por lo menos un derivado de dolastatina-10 - Google Patents
Nueva composicion farmaceutica que contiene por lo menos un derivado de dolastatina-10Info
- Publication number
- PA8655401A1 PA8655401A1 PA20058655401A PA8655401A PA8655401A1 PA 8655401 A1 PA8655401 A1 PA 8655401A1 PA 20058655401 A PA20058655401 A PA 20058655401A PA 8655401 A PA8655401 A PA 8655401A PA 8655401 A1 PA8655401 A1 PA 8655401A1
- Authority
- PA
- Panama
- Prior art keywords
- pharmaceutical composition
- dolastatin
- derivative
- new pharmaceutical
- cisplatino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/282—Platinum compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A UNA COMPOSICION FARMACEUTICA, QUE CONTIENE POR LO MENOS UN COMPUESTO DE LA FORMULA (I) EN COMBINACION CON LA CAPECITABINA, EL TRASTUZUMAB, EL PERTUZUMAB, EL CISPLATINO O EL IRINOTECAN PARA LA ADMINISTRACION SIMULTANEA, SUCESIVA O SEPARADA EN EL TRATAMIENTO DEL CANCER.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04106522 | 2004-12-13 | ||
EP05100866 | 2005-02-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
PA8655401A1 true PA8655401A1 (es) | 2006-08-03 |
Family
ID=36113901
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PA20058655401A PA8655401A1 (es) | 2004-12-13 | 2005-12-12 | Nueva composicion farmaceutica que contiene por lo menos un derivado de dolastatina-10 |
Country Status (15)
Country | Link |
---|---|
US (1) | US20060292158A1 (es) |
EP (1) | EP1827603A2 (es) |
JP (1) | JP2008523002A (es) |
KR (1) | KR20070086123A (es) |
AR (1) | AR052046A1 (es) |
AU (1) | AU2005315912A1 (es) |
BR (1) | BRPI0519023A2 (es) |
CA (1) | CA2590431A1 (es) |
GT (1) | GT200500364A (es) |
MX (1) | MX2007006430A (es) |
PA (1) | PA8655401A1 (es) |
PE (1) | PE20060747A1 (es) |
RU (1) | RU2007126358A (es) |
TW (1) | TW200635609A (es) |
WO (1) | WO2006063707A2 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9200034B2 (en) | 2011-03-16 | 2015-12-01 | Council Of Scientific & Industrial Research | Oligopeptides and process for preparation thereof |
MX368259B (es) | 2013-04-16 | 2019-09-25 | Genentech Inc | Variantes de pertuzumab y su evaluacion. |
WO2015095953A1 (en) | 2013-12-27 | 2015-07-02 | The Centre For Drug Research And Development | Sulfonamide-containing linkage systems for drug conjugates |
CA3230737A1 (en) | 2021-09-03 | 2023-03-09 | Toray Industries, Inc. | Pharmaceutical composition for cancer treatment and/or prevention |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4287523B2 (ja) * | 1998-12-28 | 2009-07-01 | あすか製薬株式会社 | 抗腫瘍剤 |
EP2266607A3 (en) * | 1999-10-01 | 2011-04-20 | Immunogen, Inc. | Immunoconjugates for treating cancer |
US6737409B2 (en) * | 2001-07-19 | 2004-05-18 | Hoffmann-La Roche Inc. | Dolastatin 10 derivatives |
US7968569B2 (en) * | 2002-05-17 | 2011-06-28 | Celgene Corporation | Methods for treatment of multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione |
-
2005
- 2005-12-05 WO PCT/EP2005/012992 patent/WO2006063707A2/en active Application Filing
- 2005-12-05 BR BRPI0519023-1A patent/BRPI0519023A2/pt not_active Application Discontinuation
- 2005-12-05 JP JP2007544793A patent/JP2008523002A/ja active Pending
- 2005-12-05 EP EP05813987A patent/EP1827603A2/en not_active Withdrawn
- 2005-12-05 AU AU2005315912A patent/AU2005315912A1/en not_active Abandoned
- 2005-12-05 MX MX2007006430A patent/MX2007006430A/es not_active Application Discontinuation
- 2005-12-05 RU RU2007126358/15A patent/RU2007126358A/ru not_active Application Discontinuation
- 2005-12-05 KR KR1020077013301A patent/KR20070086123A/ko not_active Application Discontinuation
- 2005-12-05 CA CA002590431A patent/CA2590431A1/en not_active Abandoned
- 2005-12-08 US US11/297,716 patent/US20060292158A1/en not_active Abandoned
- 2005-12-09 PE PE2005001424A patent/PE20060747A1/es not_active Application Discontinuation
- 2005-12-09 TW TW094143767A patent/TW200635609A/zh unknown
- 2005-12-12 AR ARP050105194A patent/AR052046A1/es not_active Application Discontinuation
- 2005-12-12 PA PA20058655401A patent/PA8655401A1/es unknown
- 2005-12-12 GT GT200500364A patent/GT200500364A/es unknown
Also Published As
Publication number | Publication date |
---|---|
EP1827603A2 (en) | 2007-09-05 |
CA2590431A1 (en) | 2006-06-22 |
MX2007006430A (es) | 2007-07-19 |
WO2006063707A2 (en) | 2006-06-22 |
GT200500364A (es) | 2006-08-02 |
KR20070086123A (ko) | 2007-08-27 |
PE20060747A1 (es) | 2006-09-01 |
US20060292158A1 (en) | 2006-12-28 |
JP2008523002A (ja) | 2008-07-03 |
RU2007126358A (ru) | 2009-01-20 |
BRPI0519023A2 (pt) | 2008-12-23 |
AR052046A1 (es) | 2007-02-28 |
TW200635609A (en) | 2006-10-16 |
WO2006063707A3 (en) | 2006-10-26 |
AU2005315912A1 (en) | 2006-06-22 |
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