CO6341577A2 - Oligonucleotidos antisentido dirigidos contra el factor de crecimiento del tejido conectivo y usos de los mismos - Google Patents

Oligonucleotidos antisentido dirigidos contra el factor de crecimiento del tejido conectivo y usos de los mismos

Info

Publication number
CO6341577A2
CO6341577A2 CO11034740A CO11034740A CO6341577A2 CO 6341577 A2 CO6341577 A2 CO 6341577A2 CO 11034740 A CO11034740 A CO 11034740A CO 11034740 A CO11034740 A CO 11034740A CO 6341577 A2 CO6341577 A2 CO 6341577A2
Authority
CO
Colombia
Prior art keywords
growth factor
antisentido
oligonucleotid
same
directed against
Prior art date
Application number
CO11034740A
Other languages
English (en)
Spanish (es)
Inventor
Nicholas M Dean
J Gordon Foulkes
Niall Odonnell
Frank Bennett
Susan M Freier
Original Assignee
Excaliard Pharmaceuticals Inc
Isis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Excaliard Pharmaceuticals Inc, Isis Pharmaceuticals Inc filed Critical Excaliard Pharmaceuticals Inc
Publication of CO6341577A2 publication Critical patent/CO6341577A2/es

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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7115—Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/712—Nucleic acids or oligonucleotides having modified sugars, i.e. other than ribose or 2'-deoxyribose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
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    • C12N2310/323—Chemical structure of the sugar modified ring structure
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CO11034740A 2008-08-25 2011-03-22 Oligonucleotidos antisentido dirigidos contra el factor de crecimiento del tejido conectivo y usos de los mismos CO6341577A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19012108P 2008-08-25 2008-08-25

Publications (1)

Publication Number Publication Date
CO6341577A2 true CO6341577A2 (es) 2011-11-21

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CO11034740A CO6341577A2 (es) 2008-08-25 2011-03-22 Oligonucleotidos antisentido dirigidos contra el factor de crecimiento del tejido conectivo y usos de los mismos

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Country Link
US (6) US8252762B2 (OSRAM)
EP (2) EP3081648A1 (OSRAM)
JP (5) JP5420668B2 (OSRAM)
KR (2) KR101877698B1 (OSRAM)
CN (2) CN103429270B (OSRAM)
AU (2) AU2009275387B2 (OSRAM)
BR (1) BRPI0912923A8 (OSRAM)
CA (1) CA2733262C (OSRAM)
CO (1) CO6341577A2 (OSRAM)
DK (1) DK2331141T3 (OSRAM)
EA (1) EA022207B1 (OSRAM)
ES (1) ES2566508T3 (OSRAM)
GB (1) GB2465902B (OSRAM)
IL (3) IL211230A (OSRAM)
MX (2) MX2011002143A (OSRAM)
NZ (2) NZ591416A (OSRAM)
SG (1) SG196769A1 (OSRAM)
WO (1) WO2010042281A2 (OSRAM)
ZA (1) ZA201101549B (OSRAM)

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