CN1633286A - 作为中性白细胞存活和激活因子的中链长度的脂肪酸、甘油酯和类似物 - Google Patents

作为中性白细胞存活和激活因子的中链长度的脂肪酸、甘油酯和类似物 Download PDF

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Publication number
CN1633286A
CN1633286A CNA028094263A CN02809426A CN1633286A CN 1633286 A CN1633286 A CN 1633286A CN A028094263 A CNA028094263 A CN A028094263A CN 02809426 A CN02809426 A CN 02809426A CN 1633286 A CN1633286 A CN 1633286A
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patient
neutropenia
treats
mct
general formula
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Chinese (zh)
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L·加尼翁
J·巴拉比
P·劳林
C·彭尼
B·扎卡里
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Prometic Biosciences Inc
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Prometic Biosciences Inc
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    • C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
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    • C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
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  • Medicinal Chemistry (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CNA028094263A 2001-04-18 2002-04-18 作为中性白细胞存活和激活因子的中链长度的脂肪酸、甘油酯和类似物 Pending CN1633286A (zh)

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US28445801P 2001-04-18 2001-04-18
US60/284,458 2001-04-18

Publications (1)

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CN1633286A true CN1633286A (zh) 2005-06-29

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CNA028094263A Pending CN1633286A (zh) 2001-04-18 2002-04-18 作为中性白细胞存活和激活因子的中链长度的脂肪酸、甘油酯和类似物

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US (2) US7745488B2 (OSRAM)
EP (2) EP1900364B1 (OSRAM)
JP (3) JP5026655B2 (OSRAM)
KR (1) KR20030096323A (OSRAM)
CN (1) CN1633286A (OSRAM)
AP (1) AP1740A (OSRAM)
AU (2) AU2002308456B2 (OSRAM)
BG (1) BG66418B1 (OSRAM)
BR (1) BR0208984A (OSRAM)
CA (2) CA2444463C (OSRAM)
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EA (1) EA007322B1 (OSRAM)
EE (1) EE200300510A (OSRAM)
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HU (1) HUP0303817A3 (OSRAM)
IL (3) IL158322A0 (OSRAM)
MX (1) MXPA03009436A (OSRAM)
NO (1) NO335105B1 (OSRAM)
NZ (2) NZ528690A (OSRAM)
OA (1) OA12506A (OSRAM)
PL (2) PL223348B1 (OSRAM)
PT (2) PT1900364E (OSRAM)
SI (1) SI1385498T1 (OSRAM)
SK (1) SK12772003A3 (OSRAM)
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101903028A (zh) * 2007-12-19 2010-12-01 普罗米蒂克生物科学公司 与吉西他滨组合用于治疗胰腺癌的中等链长脂肪酸、盐类及三酸甘油酯
CN102099024B (zh) * 2008-06-19 2015-11-25 犹他大学研究基金会 硝化脂质在毒性医疗疗法的副作用的治疗上的用途
CN106535887A (zh) * 2014-05-15 2017-03-22 株式会社Enzychem生命科学 治疗白细胞减少症和血小板减少症的方法
CN111902389A (zh) * 2018-03-26 2020-11-06 株式会社Enzychem生命科学 1,2-二酰基甘油化合物、其制备方法和含有其作为活性成分的免疫调节剂

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WO2002083120A2 (en) * 2001-04-18 2002-10-24 Prometic Biosciences Inc. Medium-chain length fatty acids, glycerides and analogues as neutrophil survival and activation factors
AP2005003367A0 (en) * 2003-02-07 2005-09-30 Prometic Biosciences Inc Medium-chain length fatty acids, glycerides and analogues as stimulators of erythropoiesis.
PL1648851T3 (pl) 2003-07-25 2007-09-28 Prometic Biosciences Inc Wytwarzanie soli średniołańcuchowych kwasów tłuszczowych z metalami
KR20070044805A (ko) * 2004-04-15 2007-04-30 키아스마, 인코포레이티드 생물학적 장벽 투과를 촉진시킬 수 있는 조성물
US20070219131A1 (en) * 2004-04-15 2007-09-20 Ben-Sasson Shmuel A Compositions capable of facilitating penetration across a biological barrier
BRPI0515136A (pt) * 2004-09-03 2008-07-08 Prometic Biosciences Inc derivados de purinila substituìdos com atividade imunomoduladora e quimioprotetora, seus usos isolados ou com ácidos graxos ou glicerìdeos de comprimento de cadeia médio e respectivas composições
EP1804780B1 (en) * 2004-10-01 2011-11-16 ProMetic BioSciences Inc. Medium-chain length fatty alcohols as stimulators of hematopoiesis
US8071580B2 (en) 2004-10-01 2011-12-06 Prometic Biosciences Inc. Medium-chain length fatty alcohols as stimulators of hematopoiesis
WO2006090289A2 (en) * 2005-02-28 2006-08-31 Alphabeta Ab Compounds for reducing aggregation of amyloid beta-peptide
JP2009537137A (ja) * 2006-05-17 2009-10-29 コグネート セラピューティクス，インコーポレーテッド 脂肪吸引後の脂肪吸引物からの造血幹細胞の単離および精製
WO2009017802A1 (en) 2007-08-01 2009-02-05 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Nitro-fattyacid modulation of type ii diabetes
CA2704286C (en) * 2007-11-02 2016-08-23 Prometic Biosciences Inc. Medium-chain length fatty acids and glycerides as nephroprotection agents
US20090326070A1 (en) 2008-05-01 2009-12-31 Complexa Inc. Vinyl substituted fatty acids
US20140024713A1 (en) 2008-06-19 2014-01-23 University Of Utah Research Foundation Use of nitrated lipids for treatment of side effects of toxic medical therapies
JP5623406B2 (ja) 2008-09-17 2014-11-12 キアズマ インコーポレイテッド 医薬組成物および関連する送達方法
EP2165713B1 (en) * 2008-09-19 2012-11-14 Nestec S.A. Whey and thymus function
JP2013500966A (ja) 2009-07-31 2013-01-10 ユニバーシティー オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケーション 抗炎症剤としての脂肪酸
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