MA53188A1 - Composés aromatiques et leurs utilisations pharmaceutiques - Google Patents
Composés aromatiques et leurs utilisations pharmaceutiquesInfo
- Publication number
- MA53188A1 MA53188A1 MA53188A MA53188A MA53188A1 MA 53188 A1 MA53188 A1 MA 53188A1 MA 53188 A MA53188 A MA 53188A MA 53188 A MA53188 A MA 53188A MA 53188 A1 MA53188 A1 MA 53188A1
- Authority
- MA
- Morocco
- Prior art keywords
- diseases
- phospholipid
- prodrug
- solvate
- relates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
- C07C65/28—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups having unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
- C07C63/64—Monocyclic acids with unsaturation outside the aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/53—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/54—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
- C07C63/04—Monocyclic monocarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
Abstract
La présente invention concerne des composés de formule générale (i) : dans laquelle r1, r2, r3, r4, r5, r6 et r7 peuvent être choisis parmi différents substituants; n vaut 0, 1 ou 2; et x est un hydroxyméthyle ou un acide carboxylique ou un dérivé de celui-ci, tel qu'un carboxylate, ester carboxylique, glycéride, anhydride, phospholipide, carboxamide, phospholipide, ou un promédicament de celui-ci; ou un sel, solvate, solvate de ce sel ou promédicament pharmaceutiquement acceptable de celui-ci. La présente invention concerne également des compositions pharmaceutiques et des compositions lipidiques comprenant au moins un composé selon l'invention, ainsi que des composés destinés à être utilisés comme médicaments ou en thérapie, en particulier dans le traitement de maladies relatives au domaine des maladies métaboliques et hépatiques, telles que la stéatose hépatique non alcoolique et des maladies de la cholestase.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862744461P | 2018-10-11 | 2018-10-11 | |
PCT/IB2019/001139 WO2020074964A1 (fr) | 2018-10-11 | 2019-10-10 | Composés aromatiques et leurs utilisations pharmaceutiques |
Publications (1)
Publication Number | Publication Date |
---|---|
MA53188A1 true MA53188A1 (fr) | 2021-12-31 |
Family
ID=68655570
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA53188A MA53188A1 (fr) | 2018-10-11 | 2019-10-10 | Composés aromatiques et leurs utilisations pharmaceutiques |
Country Status (17)
Country | Link |
---|---|
US (1) | US20210380521A1 (fr) |
EP (1) | EP3864001A1 (fr) |
JP (1) | JP2022504707A (fr) |
KR (1) | KR20210091150A (fr) |
CN (1) | CN113166024A (fr) |
AU (1) | AU2019358595A1 (fr) |
BR (1) | BR112021006907A2 (fr) |
CA (1) | CA3112073A1 (fr) |
CL (1) | CL2021000846A1 (fr) |
CO (1) | CO2021006087A2 (fr) |
EA (1) | EA202190890A1 (fr) |
IL (1) | IL282134A (fr) |
MA (1) | MA53188A1 (fr) |
MX (1) | MX2021003750A (fr) |
PH (1) | PH12021550744A1 (fr) |
SG (1) | SG11202103011YA (fr) |
WO (1) | WO2020074964A1 (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2023065200A1 (fr) * | 2021-10-21 | 2023-04-27 | Givaudan Sa | Composés organiques |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100959356B1 (ko) * | 2001-06-12 | 2010-05-20 | 웰스테트 테라퓨틱스 코포레이션 | 대사 질환의 치료용 화합물 |
AU2003261935A1 (en) * | 2002-09-06 | 2004-03-29 | Takeda Pharmaceutical Company Limited | Furan or thiophene derivative and medicinal use thereof |
WO2006066894A1 (fr) * | 2004-12-24 | 2006-06-29 | Ctg Pharma S.R.L. | Composes destines au traitement d'un syndrome metabolique |
NZ542072A (en) * | 2003-02-13 | 2007-11-30 | Wellstat Therapeutics Corp | Compounds for the treatment of metabolic disorders |
UA83509C2 (en) * | 2003-10-15 | 2008-07-25 | Оси Фармасьютикалз, Инк. | Imidazopyrazines as tyrosine kinase inhibitors |
CA2547547A1 (fr) * | 2003-12-05 | 2005-06-16 | Actelion Pharmaceuticals Ltd | Derives de diazabicyclononene et leur utilisation en tant qu'inhibiteurs de la renine |
TW200724138A (en) * | 2005-03-29 | 2007-07-01 | Sk Corp | Substituted carboxylic acid derivatives for the treatment of diabetes and lipid disorders, their preparation and use |
CN101218199A (zh) * | 2005-05-09 | 2008-07-09 | 阿斯利康(瑞典)有限公司 | 新化合物ⅰ |
GB0522433D0 (en) * | 2005-11-03 | 2005-12-14 | Astrazeneca Ab | Therapeutic agents |
RU2008136898A (ru) * | 2006-02-15 | 2010-03-20 | Санофи-Авентис (Fr) | Азациклил-замещенные арилдигидроизохинолиноны, способ их получения и их применение в качестве лекарственных средств |
MX2009011615A (es) * | 2007-06-05 | 2009-11-10 | Sanofi Aventis | Acidos benzoilamino-indan-2-carboxilicos sustituidos y compuestos relacionados. |
BRPI0907987A2 (pt) * | 2008-03-13 | 2015-11-24 | Basf Se | uso de malonatos de benzilideno, processo para a preparação de compostos, preparação cosmética, e compostos |
US20090298923A1 (en) * | 2008-05-13 | 2009-12-03 | Genmedica Therapeutics Sl | Salicylate Conjugates Useful for Treating Metabolic Disorders |
EP2313360B1 (fr) * | 2008-07-28 | 2012-09-05 | Syddansk Universitet | Composés destinés au traitement de troubles métaboliques |
MX366137B (es) * | 2009-05-08 | 2019-06-28 | Pronova Biopharma Norge As | Acidos grasos poliinsaturados para el tratamiento de trastornos relacionados a las areas de los trastornos cardiovasculares, metabolicos e inflamatorios. |
US9242987B2 (en) * | 2009-10-20 | 2016-01-26 | Cellzome Limited | Heterocyclyl pyrazolopyrimidine analogues as JAK inhibitors |
EA020849B1 (ru) * | 2009-11-26 | 2015-02-27 | Женфит | Применение 1,3-дифенилпроп-2-ен-1-оновых производных для лечения заболеваний печени |
WO2013173441A2 (fr) * | 2012-05-16 | 2013-11-21 | Glaxosmithkline Llc | Inhibiteurs d'homologue d'activateur de zeste 2 |
US20170305943A1 (en) * | 2014-05-21 | 2017-10-26 | Taxis Pharmaceuticals, Inc. | Compounds for the treatment of bacterial infections |
GB2543478A (en) * | 2015-09-07 | 2017-04-26 | Manchester Metropolitan Univ | Glycomimetics |
-
2019
- 2019-10-10 JP JP2021519840A patent/JP2022504707A/ja active Pending
- 2019-10-10 AU AU2019358595A patent/AU2019358595A1/en active Pending
- 2019-10-10 EA EA202190890A patent/EA202190890A1/ru unknown
- 2019-10-10 SG SG11202103011YA patent/SG11202103011YA/en unknown
- 2019-10-10 US US17/284,022 patent/US20210380521A1/en active Pending
- 2019-10-10 EP EP19809143.1A patent/EP3864001A1/fr active Pending
- 2019-10-10 BR BR112021006907-0A patent/BR112021006907A2/pt unknown
- 2019-10-10 WO PCT/IB2019/001139 patent/WO2020074964A1/fr unknown
- 2019-10-10 KR KR1020217014095A patent/KR20210091150A/ko unknown
- 2019-10-10 MA MA53188A patent/MA53188A1/fr unknown
- 2019-10-10 CN CN201980067283.2A patent/CN113166024A/zh active Pending
- 2019-10-10 MX MX2021003750A patent/MX2021003750A/es unknown
- 2019-10-10 CA CA3112073A patent/CA3112073A1/fr active Pending
-
2021
- 2021-04-05 PH PH12021550744A patent/PH12021550744A1/en unknown
- 2021-04-05 CL CL2021000846A patent/CL2021000846A1/es unknown
- 2021-04-07 IL IL282134A patent/IL282134A/en unknown
- 2021-05-11 CO CONC2021/0006087A patent/CO2021006087A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
JP2022504707A (ja) | 2022-01-13 |
SG11202103011YA (en) | 2021-04-29 |
CL2021000846A1 (es) | 2021-11-12 |
US20210380521A1 (en) | 2021-12-09 |
CO2021006087A2 (es) | 2021-08-09 |
AU2019358595A1 (en) | 2021-05-27 |
EA202190890A1 (ru) | 2021-09-10 |
WO2020074964A1 (fr) | 2020-04-16 |
KR20210091150A (ko) | 2021-07-21 |
EP3864001A1 (fr) | 2021-08-18 |
MX2021003750A (es) | 2021-06-15 |
CA3112073A1 (fr) | 2020-04-16 |
IL282134A (en) | 2021-05-31 |
CN113166024A (zh) | 2021-07-23 |
BR112021006907A2 (pt) | 2021-09-08 |
PH12021550744A1 (en) | 2022-02-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MA33341B1 (fr) | Acides gras polyinsaturés pour le traitement de maladies relatives au domaine des maladies cardiovasculaires, métaboliques et inflammatoires | |
MA44721A (fr) | Inhibiteurs de mcl1 macrocycliques pour le traitement du cancer | |
MA37762B1 (fr) | Composés n-aryltriazole utilisés comme antagonistes de lpar | |
MA37764A1 (fr) | Composés n-alkyltriazole utilisés comme antagonistes de lpar | |
MA33083B1 (fr) | Nouveaux lipides contenant du soufre pour utilisation en tant que supplément alimentaire ou médicament | |
MA33105B1 (fr) | Esters (1-phényl-2-pyridin-4-yl) éthyliques d'acide benzoïque en tant qu'inhibiteurs de la phosphodiestérase | |
MA32798B1 (fr) | Acides naphtylacétiques | |
MA29775B1 (fr) | Derives de pyrazolone | |
MA34903B1 (fr) | Derives de type azaindazole ou diazaindazole utilises comme medicaments | |
SK147097A3 (en) | Fatty acid esters as bioactive compounds | |
FR2356424A1 (fr) | Compositions pharmaceutiques a base d'acide phophono-formique utiles pour lutter contre les infections virales | |
TNSN08445A1 (fr) | Derives de triazolopyrazine utiles comme agent anticancereux | |
MA32009B1 (fr) | Nouveaux derives de pyrazolo [3,4-d]pyrimidine en tant qu'agents anticancereux | |
MA29311B1 (fr) | Derives d'isoxazolines et son nouveau procede de production | |
MA37765A1 (fr) | Composés de pyrazole substitués utilisés comme antagonistes de lpar | |
MA33462B1 (fr) | Formulation pharmaceutique | |
MA32108B1 (fr) | Derives d'indazole | |
MA53188A1 (fr) | Composés aromatiques et leurs utilisations pharmaceutiques | |
JPH08506347A (ja) | 皮膚炎の治療のための3,4−ジアリールクロマン | |
US20100160427A1 (en) | Method of treating vascular injuries induced by an excess of plasma lipids using combinations of vasoprotective agents | |
MA47082B1 (fr) | Amides aromatiques d'acide carboxylique en tant qu'antagonistes des recepteurs bradykinin b1 | |
FR2405067A1 (fr) | Compositions pharmaceutiques contenant des derives monofonctionnels du psoralene pour le traitement des affections cutanees | |
MA57379B1 (fr) | Modulateurs du recepteur alpha associe aux oestrogenes (err-alpha) | |
CA2366829A1 (fr) | Nouveaux derives de morpholine, procede pour leur preparation et compositions pharmaceutiques les contenant | |
FR3057772B1 (fr) | Derives d'acides quiniques polysubstitues et leurs utilisations |