MA33341B1 - Acides gras polyinsaturés pour le traitement de maladies relatives au domaine des maladies cardiovasculaires, métaboliques et inflammatoires - Google Patents
Acides gras polyinsaturés pour le traitement de maladies relatives au domaine des maladies cardiovasculaires, métaboliques et inflammatoiresInfo
- Publication number
- MA33341B1 MA33341B1 MA34421A MA34421A MA33341B1 MA 33341 B1 MA33341 B1 MA 33341B1 MA 34421 A MA34421 A MA 34421A MA 34421 A MA34421 A MA 34421A MA 33341 B1 MA33341 B1 MA 33341B1
- Authority
- MA
- Morocco
- Prior art keywords
- metabolic
- diseases
- treatment
- field
- cardiovascular
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
- C07C57/03—Monocarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- C07D263/26—Oxygen atoms attached in position 2 with hetero atoms or acyl radicals directly attached to the ring nitrogen atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/60—Unsaturated compounds containing ether groups, groups, groups, or groups the non-carboxylic part of the ether being unsaturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
- C07C69/675—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids of saturated hydroxy-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
- C07C69/675—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids of saturated hydroxy-carboxylic acids
- C07C69/68—Lactic acid esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
- C07C69/708—Ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Abstract
LA PRÉSENTE INVENTION CONCERNE DES COMPOSÉS LIPIDIQUES DE LA FORMULE GÉNÉRALE (I): R1-O-C(R2)(R3) -X (I) DANS LAQUELLE R1 EST UN GROUPE ALKYLE C10-C22, UN GROUPE ALCÉNYLE C10-C22 AYANT 1 À 6 DOUBLES LIAISONS, OU UN GROUPE ALKYNYLE C10-C22 AYANT 1 À 6 TRIPLES LIAISONS; R2 ET R3 SONT IDENTIQUES OU DIFFÉRENTS ET PEUVENT ÊTRE CHOISIS PARMI DIFFÉRENTS SUBSTITUANTS; ET X EST UN ACIDE CARBOXYLIQUE OU UN DÉRIVÉ DE CELUI-CI, TEL QU'UN ESTER CARBOXYLIQUE, UN ANHYDRIDE CARBOXYLIQUE, UN PHOSPHOLIPIDE, UN TRIGLYCÉRIDE OU UN CARBOXAMIDE; OU UN SEL PHARMACEUTIQUEMENT ACCEPTABLE, UN SOLVATE, UN SOLVATE DE CE SEL ET UN PROMÉDICAMENT DE CELUI-CI. LA PRÉSENTE INVENTION CONCERNE ÉGALEMENT DES COMPOSITIONS PHARMACEUTIQUES ET DES COMPOSITIONS LIPIDIQUES COMPRENANT AU MOINS UN COMPOSÉ DE CETTE INVENTION, AINSI QUE DES COMPOSÉS DESTINÉS À ÊTRE UTILISÉS COMME MÉDICAMENTS OU EN THÉRAPIE, EN PARTICULIER DANS LE TRAITEMENT DE MALADIES RELATIVES AU DOMAINE DES MALADIES CARDIO-VASCULAIRES, MÉTABOLIQUES ET INFLAMMATOIRES.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17650309P | 2009-05-08 | 2009-05-08 | |
PCT/IB2010/001251 WO2010128401A1 (fr) | 2009-05-08 | 2010-05-07 | Acides gras polyinsaturés pour le traitement de maladies relatives au domaine des maladies cardiovasculaires, métaboliques et inflammatoires. |
Publications (1)
Publication Number | Publication Date |
---|---|
MA33341B1 true MA33341B1 (fr) | 2012-06-01 |
Family
ID=43050039
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA34421A MA33341B1 (fr) | 2009-05-08 | 2010-05-07 | Acides gras polyinsaturés pour le traitement de maladies relatives au domaine des maladies cardiovasculaires, métaboliques et inflammatoires |
Country Status (29)
Country | Link |
---|---|
US (2) | US8735436B2 (fr) |
EP (1) | EP2427415B1 (fr) |
JP (2) | JP5843755B2 (fr) |
KR (1) | KR101783817B1 (fr) |
CN (1) | CN102459142B (fr) |
AR (2) | AR078507A1 (fr) |
AU (1) | AU2010244136B2 (fr) |
BR (1) | BRPI1015120B8 (fr) |
CA (1) | CA2760877C (fr) |
CL (1) | CL2011002745A1 (fr) |
CO (1) | CO6430454A2 (fr) |
DK (1) | DK2427415T3 (fr) |
EA (1) | EA021177B1 (fr) |
ES (1) | ES2726765T3 (fr) |
HR (1) | HRP20190732T1 (fr) |
IL (1) | IL216171A (fr) |
MA (1) | MA33341B1 (fr) |
MX (2) | MX2011011614A (fr) |
MY (1) | MY165292A (fr) |
NZ (2) | NZ596386A (fr) |
PH (1) | PH12015500930A1 (fr) |
PL (1) | PL2427415T3 (fr) |
PT (1) | PT2427415T (fr) |
SG (1) | SG175401A1 (fr) |
TR (1) | TR201905768T4 (fr) |
TW (1) | TWI558395B (fr) |
UA (1) | UA109528C2 (fr) |
WO (1) | WO2010128401A1 (fr) |
ZA (2) | ZA201108163B (fr) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2733353T3 (es) | 2007-11-09 | 2019-11-28 | Basf As | Compuestos lípidos para uso en productos cosméticos, como suplemento alimenticio o como un medicamento |
NZ588603A (en) | 2008-03-26 | 2012-03-30 | Oramed Ltd | Methods and compositions for oral administration of a protein of up to 100000 Daltaons, a first protease inhibitor and a second protease inhibitor wherein said protease inhibitors inhibit trypsin |
EP2147910A1 (fr) | 2008-07-15 | 2010-01-27 | Pronova BioPharma Norge AS | Nouveaux composés lipidiques |
SG175401A1 (en) | 2009-05-08 | 2011-12-29 | Pronova Biopharma Norge As | Polyunsaturated fatty acids for the treatment of diseases related to cardiovascular, metabolic and inflammatory disease areas |
NZ599618A (en) | 2009-10-30 | 2014-08-29 | Tharos Ltd | Solvent-free process for obtaining phospholipids and neutral enriched krill oils |
GB201014633D0 (en) | 2010-09-02 | 2010-10-13 | Avexxin As | Rheumatoid arthritis treatment |
MY170076A (en) * | 2010-11-05 | 2019-07-03 | Pronova Biopharma Norge As | Methods of treatment using lipid compounds |
WO2014083528A2 (fr) * | 2012-12-02 | 2014-06-05 | Mahesh Kandula | Compositions et méthodes pour le traitement de maladies cardio-vasculaires et de troubles lipidiques |
EP4215205A1 (fr) | 2013-01-03 | 2023-07-26 | Oramed Ltd. | Procédés et compositions pour le traitement de nafld, de la stéatose hépatique et de ses séquelles |
WO2014132134A1 (fr) * | 2013-02-28 | 2014-09-04 | Pronova Biopharma Norge As | Composition comprenant un composé lipidique, un triglycéride et un tensioactif, et procédés d'utilisation associés |
CN107673964B (zh) * | 2013-02-28 | 2021-03-23 | 普罗诺瓦生物医药挪威公司 | 制备2-((5z,8z,11z,14z,17z)-二十碳-5,8,11,14,17-五烯基氧基)丁酸的方法 |
GB201409363D0 (en) | 2014-05-27 | 2014-07-09 | Avexxin As | Skin cancer treatment |
US20180110747A1 (en) * | 2015-04-01 | 2018-04-26 | Pronova Biopharma Norge As | Use of thia oxo compounds for lowering apo c3 |
JP7341916B2 (ja) * | 2015-04-01 | 2023-09-11 | ビーエーエスエフ エーエス | アポc3を低下させるためのチアオキソ化合物の使用 |
US20180104201A1 (en) | 2015-04-28 | 2018-04-19 | Pronova Biopharma Norge As | Use of structurally enhanced fatty acids containing sulphur for preventing and or treating non alcoholic steatohepatitis |
GB201521085D0 (en) * | 2015-11-30 | 2016-01-13 | Biozep As | Use |
GB201604316D0 (en) | 2016-03-14 | 2016-04-27 | Avexxin As | Combination therapy |
AU2017329957B2 (en) | 2016-09-21 | 2020-05-07 | Avexxin As | Pharmaceutical composition |
WO2019083816A1 (fr) | 2017-10-23 | 2019-05-02 | Epitracker, Inc. | Analogues d'acides gras et leur utilisation dans le traitement des états liés au syndrome métabolique |
KR20200096791A (ko) | 2017-12-06 | 2020-08-13 | 바스프 에이에스 | 비알콜성 지방간염 치료용 지방산 유도체 |
WO2019222254A1 (fr) * | 2018-05-16 | 2019-11-21 | Epitracker, Inc. | Compositions et procédés de diagnostic et de traitement d'états liés au vieillissement |
JP2021526552A (ja) * | 2018-05-23 | 2021-10-07 | ノースシー セラピューティクス ベスローテン フェンノートシャップ | 血糖制御を改善し、炎症性腸疾患を処置するための構造修飾脂肪酸 |
US20210380521A1 (en) * | 2018-10-11 | 2021-12-09 | Basf As | Aromatic compounds and pharmaceutical uses thereof |
BR112022001488A2 (pt) | 2019-07-29 | 2022-04-19 | Heparegenix Gmbh | Inibidores de proteínas quinases de pirazolo-piridina substituída com heteroarila para promover regeneração do fígado ou redução ou prevenção de morte de hepatócitos |
CN114981267A (zh) | 2020-01-15 | 2022-08-30 | 海帕瑞吉尼克斯股份有限公司 | 用于治疗肝脏疾病的mkk4抑制剂3-苯甲酰基-1h-吡咯并[2,3-b]吡啶衍生物 |
EP4267124A1 (fr) | 2020-12-22 | 2023-11-01 | Northsea Therapeutics B.V. | Polythérapies comprenant des acides gras structuralement améliorés contenant de l'oxygène pour le traitement de la stéatohépatite non alcoolique |
Family Cites Families (77)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2909554A (en) | 1956-07-23 | 1959-10-20 | Monsanto Chemicals | Process for the manufacture of (alkylmercapto) alkyl sulfates |
GB1038723A (fr) | 1962-03-26 | |||
US4040781A (en) | 1974-06-06 | 1977-08-09 | Lever Brothers Company | Novel 2-(alkylsulfinyl)ethyl sulfates and compositions employing same |
US4032564A (en) * | 1974-09-09 | 1977-06-28 | Zoecon Corporation | Esters of cyclopropylalkanols |
GB1523276A (en) | 1974-09-20 | 1978-08-31 | Lafon Labor | Sulphur-containing amino compounds |
US4009211A (en) | 1975-07-29 | 1977-02-22 | Gulf Research & Development Company | Beta,beta-dialkylethylmercaptoethoxylate as new compounds |
US4209410A (en) | 1976-04-28 | 1980-06-24 | Phillips Petroleum Company | Lubricants |
DE2861974D1 (en) | 1977-11-11 | 1982-09-16 | Ciba Geigy Ag | Pyridine dicarboxylic acid derivatives, their mixtures with metallic stabilisers and their use in stabilising chlorine-containing thermoplasts |
JPS5570841A (en) | 1978-11-24 | 1980-05-28 | Konishiroku Photo Ind Co Ltd | Forming method of dye image |
US4368190A (en) | 1980-04-17 | 1983-01-11 | Merck & Co., Inc. | Immunologically active dipeptidyl 4-O-,6-O-acyl-2-amino-2-deoxy-D-glucose derivatives and methods for their preparation |
DE3164332D1 (en) | 1980-10-21 | 1984-07-26 | Boehringer Mannheim Gmbh | Phospholipids that contain sulphur, process for their preparation and medicines containing these compounds |
US4411808A (en) | 1982-08-04 | 1983-10-25 | Exxon Research & Engineering Co. | Multifunctional additive for power transmission shift fluids |
US4775223A (en) | 1984-09-20 | 1988-10-04 | Canon Kabushiki Kaisha | Lactic acid derivative, liquid crystal composition containing same and liquid crystal device |
JPS6176438A (ja) * | 1984-09-20 | 1986-04-18 | Canon Inc | 乳酸誘導体 |
CA2010000A1 (fr) | 1989-04-07 | 1990-10-07 | Paul B. Merkel | Materiau d'enregistrement photographique contenant un coupleur de formation de colorant bleu-vert |
JPH0451149A (ja) | 1990-06-19 | 1992-02-19 | Fuji Photo Film Co Ltd | ハロゲン化銀カラー写真感光材料 |
FR2663928B1 (fr) | 1990-06-27 | 1994-04-08 | Norsolor | Nouveaux composes acryliques soufres, un procede pour leur preparation et leur application a la synthese de nouveaux polymeres. |
EP0487809A1 (fr) | 1990-11-28 | 1992-06-03 | Monsanto Europe S.A./N.V. | Compositions de caoutchouc ayant une usinabilité améliorée et ayant des meilleures propriétés dans leurs vulcanisats |
JPH0543529A (ja) | 1991-08-10 | 1993-02-23 | Taisho Pharmaceut Co Ltd | アルカンアミドアンモニウム化合物 |
JP2755279B2 (ja) | 1992-03-19 | 1998-05-20 | 三井化学株式会社 | 熱可塑性樹脂組成物およびその成形体 |
JP2793458B2 (ja) | 1992-03-19 | 1998-09-03 | 三井化学株式会社 | コネクター用ポリアミド系樹脂組成物およびコネクター |
WO1994028908A2 (fr) | 1993-06-10 | 1994-12-22 | Wake Forest University | (phospho)lipides contre l'infection a virus de l'hepatite b |
JP3110918B2 (ja) | 1993-06-18 | 2000-11-20 | 富士写真フイルム株式会社 | ハロゲン化銀写真感光材料 |
US5523430A (en) * | 1994-04-14 | 1996-06-04 | Bristol-Myers Squibb Company | Protein farnesyl transferase inhibitors |
GB2290789B (en) | 1994-07-01 | 1998-09-16 | Ciba Geigy Ag | Titanium and zirconium complexes of carboxylic acids as corrosion inhibitors |
EP0869941B1 (fr) | 1994-10-13 | 2001-12-12 | Peptech Limited | Acides gras polyinsatures modifies |
US7517858B1 (en) | 1995-06-07 | 2009-04-14 | The Regents Of The University Of California | Prodrugs of pharmaceuticals with improved bioavailability |
FR2741619B1 (fr) * | 1995-11-28 | 1998-02-13 | Pf Medicament | Nouveaux derives de 2,3,5-trimethyl-4-hydroxy-anilides, leur preparation et leur application en therapeutique |
CA2251780A1 (fr) * | 1996-04-12 | 1997-10-23 | Peptide Technology Pty. Limited | Procedes permettant de traiter des immunopathologies au moyen d'acides gras polyinsatures |
US6060515A (en) * | 1997-01-24 | 2000-05-09 | The Regents Of The University Of California | Treatment of skin conditions by use of PPARα activators |
JP2001509165A (ja) * | 1997-01-24 | 2001-07-10 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | バリヤ機能の回復、表皮の分化の促進及び増殖の抑制のためのFXR、PPARα及びLXRαの活性剤の使用 |
WO1999016801A1 (fr) * | 1997-10-01 | 1999-04-08 | The Procter & Gamble Company | Compose glyoxylique comprenant un ou plusieurs ingredients actifs |
JPH11180929A (ja) | 1997-12-19 | 1999-07-06 | Asahi Glass Co Ltd | エステル誘導体 |
WO1999058120A1 (fr) | 1998-05-08 | 1999-11-18 | Rolf Berge | Utilisation d'analogues d'acides gras non beta-oxydables pour traiter les etats lies au syndrome x |
FR2786187B1 (fr) | 1998-11-19 | 2001-11-09 | Univ Paris Curie | Composes du type 2-acylamino-2-deoxy-glucono-1,5-lactone, procede d'obtention, compositions les comportant et utilisations |
FR2792312B1 (fr) | 1999-04-15 | 2001-06-08 | Oreal | Composes (poly)thia-alcynoiques et leurs derives, compositions les comprenant et leur utilisation |
CA2375822A1 (fr) | 1999-06-01 | 2000-12-07 | The University Of Texas Southwestern Medical Center | Composes de diarylether substitues |
US6723717B1 (en) | 1999-06-01 | 2004-04-20 | The University Of Texas Southwestern Medical Center | Sulfur-containing thyroxane derivatives and their use as hair growth promotors |
NO328803B1 (no) | 2000-03-03 | 2010-05-18 | Thia Medica | Nye fettsyreanaloger |
UA72625C2 (uk) * | 2000-05-26 | 2005-03-15 | Ніппон Сіняку Ко., Лтд. | Гетероциклічні сполуки |
UA75083C2 (uk) | 2000-06-22 | 2006-03-15 | Тераванс, Інк. | Похідні глікопептидфосфонатів |
FR2828487B1 (fr) | 2001-08-09 | 2005-05-27 | Genfit S A | Nouveaux composes derives d'acides gras, preparation et utilisations |
US20030147814A1 (en) | 2001-12-21 | 2003-08-07 | 3M Innovative Properties Company | Medicinal aerosol formulations comprising ion pair complexes |
GB2383355A (en) | 2001-12-22 | 2003-06-25 | Schlumberger Holdings | An aqueous viscoelastic fluid containing hydrophobically modified polymer and viscoelastic surfactant |
BR0307265B1 (pt) | 2002-01-31 | 2012-11-27 | composição substancialmente isenta de solvente, emulsão concentrada, e processo para tratamento e conferência de repelência à água a materiais fibrosos, couro, peles e têxteis. | |
US7273852B2 (en) | 2002-06-13 | 2007-09-25 | The Research Foundation Of The City University Of New York | Synthetic C-glycolipid and its use for treating cancer, infectious diseases and autoimmune diseases |
FR2845991B1 (fr) | 2002-10-16 | 2005-02-04 | Pf Medicament | Derives d'alpha-phenyl acetanilides et leur application en therapeutique humaine |
US8372430B2 (en) | 2002-12-17 | 2013-02-12 | The Procter & Gamble Company | Compositions, methods, and kits useful for the alleviation of gastrointestinal effects |
WO2004076404A1 (fr) | 2003-02-28 | 2004-09-10 | Kaneka Corpration | Procedes pour la production de composes optiquement actifs comportant des substituants en position 2 |
DE10326303A1 (de) | 2003-06-11 | 2004-12-30 | Celares Gmbh | Reagenzien zur Modifikation von Biopharmazeutika, deren Herstellung und Anwendung |
WO2005073164A1 (fr) | 2004-01-30 | 2005-08-11 | Peplin Biolipids Pty Ltd | Molecules porteuses et therapeutiques |
JP4563114B2 (ja) | 2004-08-30 | 2010-10-13 | 出光興産株式会社 | 潤滑剤用添加剤 |
WO2006109491A1 (fr) | 2005-03-31 | 2006-10-19 | Yamaguchi University | Convertisseur d'energie houlomotrice |
CN101213281B (zh) * | 2005-05-04 | 2013-03-13 | 普罗诺瓦生物医药挪威公司 | 新的dha衍生物及其作为药物的用途 |
CN102050720B (zh) * | 2005-05-04 | 2013-03-13 | 普罗诺瓦生物医药挪威公司 | 新的dha衍生物及其作为药物的用途 |
US20070167529A1 (en) | 2006-01-17 | 2007-07-19 | Walton Rebecca A | Antimicrobial compositions for treating fabrics and surfaces |
EP2004169B1 (fr) | 2006-04-12 | 2012-08-08 | Unilever PLC | Composition orale comprenant un acide gras polyinsaturé et de l'acide salicylique destinée à produire un effet anti-inflammatoire dans la peau |
EP1849449A1 (fr) | 2006-04-26 | 2007-10-31 | 3M Innovative Properties Company | Composition contenant de la charge et precédé de fabrication et d'utilisation correspondants |
US7763607B2 (en) | 2006-04-27 | 2010-07-27 | Solvay Pharmaceuticals Gmbh | Pharmaceutical compositions comprising CBx cannabinoid receptor modulators and potassium channel modulators |
EA200802213A1 (ru) | 2006-05-09 | 2009-10-30 | Химекуэст Фармасьютикалз, Инк. | Способы лечения заболеваний крови |
EP2094640A4 (fr) | 2006-11-01 | 2015-05-20 | Pronova Biopharma Norge As | Lipides oméga-3 à substitution alpha en tant qu'activateurs ou modulateurs du récepteur activé par proliférateurs de peroxisome (ppar) |
WO2008053340A1 (fr) * | 2006-11-03 | 2008-05-08 | Pronova Biopharma Norge As | Produit de combinaison comprenant au moins un lipide substitué en position alpha et au moins un agent hypoglycémique |
CN101225064A (zh) | 2007-01-19 | 2008-07-23 | 上海汇瑞生物科技有限公司 | 一种制备β-硫杂-α-烷基脂肪酸的新方法 |
DE102007017179A1 (de) * | 2007-04-12 | 2008-10-23 | Clariant International Ltd. | Verfahren zur Herstellung von Alkylpolyglykolcarbonsäuren und Polyglykoldicarbonsäuren mittels Direktoxidation |
US8604004B2 (en) * | 2007-10-04 | 2013-12-10 | President And Fellows Of Harvard College | Moenomycin analogs, methods of synthesis, and uses thereof |
US20100267828A1 (en) * | 2007-10-31 | 2010-10-21 | Anne Kristin Holmeide | dha derivatives and their use as medicaments |
ES2733353T3 (es) | 2007-11-09 | 2019-11-28 | Basf As | Compuestos lípidos para uso en productos cosméticos, como suplemento alimenticio o como un medicamento |
WO2009149496A1 (fr) | 2008-06-10 | 2009-12-17 | Central Northern Adelaide Health Service | Traitement du diabète, de ses complications et de troubles associés |
FR2933006B1 (fr) | 2008-06-27 | 2010-08-20 | Inst Francais Du Petrole | Solution absorbante contenant un inhibiteur de degradation soufre a groupement carboxyle et methode pour limiter la degradation d'une solution absorbante |
US8173831B2 (en) | 2008-07-08 | 2012-05-08 | Catabasis Pharmaceuticals, Inc. | Fatty acid acetylated salicylates and their uses |
EP2147910A1 (fr) | 2008-07-15 | 2010-01-27 | Pronova BioPharma Norge AS | Nouveaux composés lipidiques |
SG175401A1 (en) | 2009-05-08 | 2011-12-29 | Pronova Biopharma Norge As | Polyunsaturated fatty acids for the treatment of diseases related to cardiovascular, metabolic and inflammatory disease areas |
JP5802209B2 (ja) | 2009-09-01 | 2015-10-28 | カタバシス ファーマシューティカルズ,インコーポレイテッド | 脂肪酸ナイアシン抱合体およびそれらの使用 |
EP2526084A1 (fr) | 2010-01-20 | 2012-11-28 | Pronova BioPharma Norge AS | Dérivés salicylates acide gras |
MY170076A (en) | 2010-11-05 | 2019-07-03 | Pronova Biopharma Norge As | Methods of treatment using lipid compounds |
WO2012115695A1 (fr) | 2011-02-25 | 2012-08-30 | Catabasis Pharmaceuticals, Inc. | Conjugués de bis-acides gras et leurs utilisations |
WO2013016531A2 (fr) | 2011-07-26 | 2013-01-31 | Purdue Research Foundation | Composés et méthodes de traitement d'une néoplasie ou d'un cancer |
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