FR2845991B1 - Derives d'alpha-phenyl acetanilides et leur application en therapeutique humaine - Google Patents

Derives d'alpha-phenyl acetanilides et leur application en therapeutique humaine

Info

Publication number
FR2845991B1
FR2845991B1 FR0212855A FR0212855A FR2845991B1 FR 2845991 B1 FR2845991 B1 FR 2845991B1 FR 0212855 A FR0212855 A FR 0212855A FR 0212855 A FR0212855 A FR 0212855A FR 2845991 B1 FR2845991 B1 FR 2845991B1
Authority
FR
France
Prior art keywords
alpha
human therapeutics
phenyl acetanilide
acetanilide derivatives
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0212855A
Other languages
English (en)
Other versions
FR2845991A1 (fr
Inventor
Jean Francois Patoiseau
Jean Marie Autin
Andre Delhon
Didier Junquero
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Original Assignee
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0212855A priority Critical patent/FR2845991B1/fr
Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Priority to CNA2003801016613A priority patent/CN1705648A/zh
Priority to CA002502505A priority patent/CA2502505A1/fr
Priority to BR0315347-9A priority patent/BR0315347A/pt
Priority to MXPA05004064A priority patent/MXPA05004064A/es
Priority to EP03780228A priority patent/EP1558590A1/fr
Priority to US10/531,234 priority patent/US20060135785A1/en
Priority to JP2004544391A priority patent/JP2006512302A/ja
Priority to PCT/FR2003/003038 priority patent/WO2004035552A1/fr
Priority to AU2003288327A priority patent/AU2003288327A1/en
Publication of FR2845991A1 publication Critical patent/FR2845991A1/fr
Application granted granted Critical
Publication of FR2845991B1 publication Critical patent/FR2845991B1/fr
Priority to ZA200502694A priority patent/ZA200502694B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR0212855A 2002-10-16 2002-10-16 Derives d'alpha-phenyl acetanilides et leur application en therapeutique humaine Expired - Fee Related FR2845991B1 (fr)

Priority Applications (11)

Application Number Priority Date Filing Date Title
FR0212855A FR2845991B1 (fr) 2002-10-16 2002-10-16 Derives d'alpha-phenyl acetanilides et leur application en therapeutique humaine
PCT/FR2003/003038 WO2004035552A1 (fr) 2002-10-16 2003-10-15 Derives d’alpha-phenil acetanilides presentant une activite inhibitrice de l’acat et leur application en therapeutique
BR0315347-9A BR0315347A (pt) 2002-10-16 2003-10-15 Derivados de alfa-fenil acetanilidas e sua aplicação em terapêutica humana
MXPA05004064A MXPA05004064A (es) 2002-10-16 2003-10-15 Derivados de alfa-fenil acetanilida que tienen una actividad inhibidora de acil coa colesterol o-acil transferasa y la aplicacion terapeutica de los mismos.
EP03780228A EP1558590A1 (fr) 2002-10-16 2003-10-15 Derives d'alpha-phenyl acetanilides presentant une activite inhibitrice de l'acat et leur application en therapeutique
US10/531,234 US20060135785A1 (en) 2002-10-16 2003-10-15 Alpha-phenyl acetanilide derivatives having an acat inhibiting activity and the therapeutic application thereof
CNA2003801016613A CN1705648A (zh) 2002-10-16 2003-10-15 具有ACAT抑制活性的а－苯基N－乙酰苯胺衍生物及其治疗应用
CA002502505A CA2502505A1 (fr) 2002-10-16 2003-10-15 Derives d'alpha-phenyl acetanilides et leur application en therapeutique humaine
AU2003288327A AU2003288327A1 (en) 2002-10-16 2003-10-15 Alpha-phenyl acetanilide derivatives having an acat inhibiting activity and the therapeutic application thereof
JP2004544391A JP2006512302A (ja) 2002-10-16 2003-10-15 ＡＣＡＴ阻害活性を有するα−フェニルアセトアニリド誘導体およびその治療的適用
ZA200502694A ZA200502694B (en) 2002-10-16 2005-04-04 Aplha-phenyl acetanilide derivatives having an acat inhibiting activity and therapeutic application thereof.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0212855A FR2845991B1 (fr) 2002-10-16 2002-10-16 Derives d'alpha-phenyl acetanilides et leur application en therapeutique humaine

Publications (2)

Publication Number Publication Date
FR2845991A1 FR2845991A1 (fr) 2004-04-23
FR2845991B1 true FR2845991B1 (fr) 2005-02-04

Family

ID=32050433

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0212855A Expired - Fee Related FR2845991B1 (fr) 2002-10-16 2002-10-16 Derives d'alpha-phenyl acetanilides et leur application en therapeutique humaine

Country Status (11)

Country Link
US (1) US20060135785A1 (fr)
EP (1) EP1558590A1 (fr)
JP (1) JP2006512302A (fr)
CN (1) CN1705648A (fr)
AU (1) AU2003288327A1 (fr)
BR (1) BR0315347A (fr)
CA (1) CA2502505A1 (fr)
FR (1) FR2845991B1 (fr)
MX (1) MXPA05004064A (fr)
WO (1) WO2004035552A1 (fr)
ZA (1) ZA200502694B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8741966B2 (en) 2007-11-09 2014-06-03 Pronova Biopharma Norge As Lipid compounds for use in cosmetic products, as food supplement or as a medicament
EP2147910A1 (fr) * 2008-07-15 2010-01-27 Pronova BioPharma Norge AS Nouveaux composés lipidiques
AU2010244136B2 (en) 2009-05-08 2016-05-12 Pronova Biopharma Norge As Polyunsaturated fatty acids for the treatment of diseases related to cardiovascular, metabolic and inflammatory disease areas
JP2014505017A (ja) 2010-11-05 2014-02-27 プロノヴァ・バイオファーマ・ノルゲ・アーエス 脂質化合物を用いる処置方法
JP6537980B2 (ja) 2013-02-28 2019-07-03 プロノヴァ・バイオファーマ・ノルゲ・アーエスＰｒｏｎｏｖａ ＢｉｏＰｈａｒｍａ Ｎｏｒｇｅ ＡＳ 脂質化合物、トリグリセリドおよび界面活性剤を含む組成物、ならびにその使用方法
CN115025079A (zh) 2015-04-28 2022-09-09 普罗诺瓦生物医药挪威公司 结构增强的含硫脂肪酸在预防和/或治疗非酒精性脂肪性肝炎中的用途
CN105418527A (zh) * 2015-12-28 2016-03-23 青岛友诚高新技术有限公司 一种具有抗乳腺导管癌活性的化合物及其制备方法、用途
CN105541741A (zh) * 2016-01-14 2016-05-04 青岛友诚高新技术有限公司 一种具有治疗冠心病活性的化合物及其制备方法
WO2019111048A1 (fr) 2017-12-06 2019-06-13 Basf As Dérivés d'acide gras pour le traitement de la stéatohépatite non alcoolique
WO2022115207A1 (fr) * 2020-11-25 2022-06-02 Trustees Of Dartmouth College Méthode permettant d'atténuer la neuroinflammation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0600950T3 (da) * 1991-08-22 1997-04-21 Warner Lambert Co Tetrazolamider som inhibitorer af ACAT
FR2741619B1 (fr) * 1995-11-28 1998-02-13 Pf Medicament Nouveaux derives de 2,3,5-trimethyl-4-hydroxy-anilides, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
MXPA05004064A (es) 2005-06-08
JP2006512302A (ja) 2006-04-13
WO2004035552A1 (fr) 2004-04-29
AU2003288327A1 (en) 2004-05-04
EP1558590A1 (fr) 2005-08-03
US20060135785A1 (en) 2006-06-22
CA2502505A1 (fr) 2004-04-29
ZA200502694B (en) 2005-11-10
CN1705648A (zh) 2005-12-07
FR2845991A1 (fr) 2004-04-23
BR0315347A (pt) 2005-08-23

Similar Documents

Publication Publication Date Title
ID22565A (id) Penggunaan nanodispersi dalam formulasi akhir obat
DK1354888T3 (da) Glukopyranosyloxypyrazolderivater og anvendelse deraf i medikamenter
EE05067B1 (et) Aminoproplfosfiinhapped ning nende kasutamine meditsiinis
EE05157B1 (et) N-[(asendatud bensüül)-4-piperidinüüli v?i pürrolidinüül]aminohüdroksüalkoksüfenüülide derivaadid, meetod nende valmistamiseks ning nende kasutamine meditsiinis
CY2013032I2 (el) Συζυγη της εξενδινης-4 και η φαρμακευτικη τους χρηση
CY2008019I2 (el) Υποκατεστημενες οξαζολιδινονες και η χρηση των στο πεδιο της πηξης αιματος
NO20014560D0 (no) Quinasoliner og terapautisk anvendelse derav
FR2866884B1 (fr) Derives d'aryl-et d'heteroaryl-piperidinecarboxylates, leur preparation et leur application en therapeutique
MA28845B1 (fr) Derives de n-(1 h-indolyl)-i h-ind0le-2-carb0xamides, leur preparation et leur application en therapeutique
FR2850377B1 (fr) Derives d'arylalkylcarbamates, leur preparation et leur application en therapeutique
EE200200271A (et) Ravimkombinatsioonid ning nende kasutamine
IS6966A (is) Cýanó-tengd díhýdrópýrimídín efnasambönd og notkun þeirra við meðhöndlun sjúkdóma
IS6967A (is) Ný cýanó-tengd díhýdrópýrimídín efnasambönd og notkun þeirra við meðhöndlun sjúkdóma
FR2845991B1 (fr) Derives d'alpha-phenyl acetanilides et leur application en therapeutique humaine
ID27576A (id) Penggunaan siklosporin dalam pengobatan penyakit-penyakit peradangan autoimun
FR2857588B1 (fr) Utilisation de beta-endorphine, d'agents exercant une activite beta-endorphine-like en cosmetique et dermatologie
FR2880023B1 (fr) Derives de n-[(4,5-diphenyl-3-alkyl-2-thienyl) methyl] amine leur preparation et leur application en therapeutique
FR2805461B1 (fr) Nouveaux agents de gommage cutane et nouvelles compositions cosmetiques
EE200400074A (et) Koostised ning nende kasutamine proliferatiivsetehaiguste raviks
FR2838960B1 (fr) Composition comprenant des photochromes et son utilisation en cosmetique
FR2850380B1 (fr) Derives d'acylaminothiazole, leur preparation et leur utilisation en therapeutique
FR2816502B1 (fr) Composition cosmetique comprenant un derive d'aminophenol et un isoflavonoide
FR2842527B1 (fr) Derives d'acyloxypyrolidine, leur preparation et leur application en therapeutique
PT1228027E (pt) Derivados de 15-hete com heteroatomo substituinte em posicao 3 e homologos com dois carbonos e metodos de utilizacao
NO20000184D0 (no) Nye purinderivater og medisinsk anvendelse derav

Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20070629